Research Groups

[631] Eukaryotic translation initiation

Protein translation initiation is a key step in the regulation of cell growth. As a consequence, dysfunctions of the translational machinery are associated with many human tumours. Our group studies global and specific regulation of initiation in mammalian cells. The objective is to characterise the elements both cis and trans which control the recruitment of mRNAs onto polysomes under defined physiological conditions.

Group Publications