Associative memory and spatial memory in the elderly. We developed original fMRI tasks tackling the neural basis of associative and spatial memory. Patients with Mild Cognitive Impairment (MCI) show a diminished activation during the associative memory task and we hope therefore to better predict patients at risk to develop Alzheimer’s disease. Current studies focus on algorithms using multivariate analysis. Spatial memory representing also a key function in MCI, we designed a new fMRI task pinpointing that particular network.  

Neuropsychology and spatial memory. We are currently applying the same experimental paradigm to stroke patients in order to verify our hypothesis (frontal ventral cortex and familiarity; parietal cortex and sequential analysis).

Language and neurodegenerative diseases. Recent data show that language is now considered as a marker of neurodegenerative disease, such as memory in Alzheimer’s disease. We conduct longitudinal studies on language in patients with progressive language disorders.

Gait and cognition. Dual-task (cognition and gait) analysis shows a close interrelationship between the two and its use in several neurodegenerative diseases. In collaborations with the Laboratoire de Cinésiologie, we are developing quantified methods of gait analysis in various neurological  disorders.

Behavioral neurology and case studies. Poorly understood neuropsychological phenomenon can be explored using experimental paradigms and fMRI.