The Pathology Department conducts research into anatomical and clinical correlations in human pathology, and in the fields of cell biology, general immunology and immunopathology.
Concerning cell biology, several teams study:
- growth factors and the oncogenes involved in the differentiation and functioning of the lymphohematopoietic system
- the functional role of certain parts of the cytoskeletal apparatus, in particular actin and intermediary filaments, and how they change in the course of the arterial pathology of scar-tissue formation and the development of epithelial tumours and conjunctive tissue
- the structure and function of the cell membrane
Research in immunology focusses on:
- Functional specialisation of T lymphocyte subsets under experimental and pathological conditions
- Synthesis and function of cytokines secreted by cells of the immune system under experimental and pathological conditions
- Regulation and function of antigen presentation under experimental and pathological conditions
Research in pathology focusses on:
- Cellular interactions promoting the development of spontaneous and provoked autoimmunity
- Role of antibodies and immune complexes in triggering vascular lesions
- Role of immune responses in pathological manifestations associated with infectious disease
- Intra- and inter-cellular communication leading to the development of cardiovascular disease
Research Groups
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- Beat Imhof - Honorary Professor
Adhesion molecules and the process of cell migration
- Marisa Jaconi
Cardiogenesis of human pluripotent stem cells and strategies of cell therapy
- Brenda Kwak
Connexins in cardiovascular disease
- Karl-Heinz Krause
Reactive oxygen species (ROS) and Embryonic stem cells
- Doron Merkler
Multiple Sclerosis
- Walter Reith
Regulation of antigen presentation and antigen presenting cells
- Thomas Braschler
The cellular microenvironment in cell transplantation
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Department of Clinical Pathology, Hospital Department of Medical Genetics, of Laboratory and Pathology
Affiliated Clinical Groups
- Constance Barazzone (Department of Paediatrics)
Factors influencing lung development: translational studies on animal and humans
- Wolf-Henning Boehncke (Department of Internal Medicine Specialities)
Mechanisms of the pathologies of the cutaneous inflammation
- Carlo Chizzolini (Department of Internal Medicine Specialities)
Inflammation, autoimmunity and extracellular matrix
- Cem Gabay (Department of Internal Medicine Specialities)
Mechanisms of articular inflammation and joint damage in arthritis
- Jorg Seebach (Department of Internal Medicine Specialities)
Laboratory for Transplantation Immunology
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- Claire-Anne Siegrist (Department of Pediatry)
Center of Vaccinology and Neonatal Immunology
- Patrice Lalive d'Epinay (Department of Clinical Neurosciences)
Neuroimmunology, Experimental autoimmune encephalitis, Multiple sclerosis.
- Monique Ghannage (Department of Internal Medicine Specialities)
Contribution of macroautophagy to the immune response during autoimmune diseases
- Jean Villard and Sylvie Ferrari-Lacraz (Department of Internal Medicine Specialities)
Transplantations and Osteoimmonology
- Pascal Senn (Department of Clinical Neurosciences)
Pascal Senn group
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