Biophysics and Cell Biology of Signaling
We want to understand in physical and molecular terms how cells talk to each other during development. This means our research is highly interdisciplinary: physics, cell biology, molecular biology, biochemistry, genetics... Indeed some of us in the lab are biologists, other physicists, chemists, engineers or mathematicians.
We are interested in the signaling events that control tissue growth: how is the shape and final size of a tissue achieved during embryogenesis?
We focus on two types of proliferation modes: growth control by morphogen gradients and asymmetric cell division in stem cells. We do this using two model systems: Drosophila and Zebrafish.