PuBLICATIONS
2018-2025
Evidence for an interaction of paracingulin with microtubules
Flinois, A., Mutero-Maeda, A., Montessuit, S., Citi, S.
microPublication Biology (2024) 10.17912/micropub.biology. 001341, 2024
Cingulin-nonmuscle myosin interaction plays a role in epithelial morphogenesis and cingulin nanoscale organization
Rouaud, F., Mauperin, M., Mutero-Maeda, A.
J. Cell Sci (2024) May 1;137(9):jcs261776. doi: 10.1242/jcs.261776.Epub 2024 May 7.
A short guide to the tight junction
Citi, S. , Fromm, M., Furuse, M., Gonzalez-Mariscal, L., Nusrat, A., Tsukita, S., Turner, J.R.
J. Cell Sci (2024) Sep 15; 137(18):jcs262353. doi: 10.142/jcs.262353. Epub 2024 Sep 25.
Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial cell organization
Flinois, A., Méan, I., Mutero-Maeda, A., Guillemot, L., Citi, S.
J. Cell Sci (2024) 137 (5):jcs260745. doi:10.1242/jcs.260745. Epub2023 may 15
Knock out of CGN and CGNL1 in MDCK cells affects claudin-2 but has a minor impact on tight junction barrer function
Maupérin, M., Sassi, A., Méan, I., Feraille, E., Citi, S.
Cells (2023) 12 (15), 2004; https://doi.org/10.3390/cells12152004
Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membrane
Rouaud, F., Huang., W., Flinois, A., Jain, K., Vasileva, E., Di Mattia, T., Mauperin, M., Parry, D.A.D., Dugina, V., Chaponnier, C., Mean, I., Montessuit,, S., Mutero-Meda, A., Yan, J., Citi, S.
J. Cell Biol. (2023) 222 (7): e202208065. https://doi.org/10.1083/jcb202208065
Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial organization
Flinois, A., Mean I, Mutero-Meda, A., Guillemot, L., Citi, S.
J. Cell Sci. Chem. (2023) doi: 10.1242/jcs260745
The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells
Sluysmans, S., Salmaso, A., Rouaud, F., Méan, I., Brini, M., Citi, S.
J. Biol. Chem. (2022) 14; 102138, doi: 10.1016/j.jbc.2022.102138
Cingulin binds to the ZU5 domain of scaffolding protein ZO-1 to promote its extended conformation, stabilization and tight junction accumulation
Vasileva, E., Spadaro, D., Rouaud, F., King, J.M., Flinois, A., Shah, J., Sluysmans, S., Jond, L., Turner, J.R., Citi, S.
J. Biol. Chem. (2022) 298(4):101797, https://doi.org/10.1016/j.jbc.2022.101797
The ACE2 receptor for coronavirus entry is localized at apical cell-cell junctions
Rouaud, F., Méan, I., Citi, S.
Cells (2022), 11, 627, https://doi.org/10.3390/cells11040627
PLEKHA5, PLEKHA6 and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to th cell periphery and regulate copper homeostasis
Sluysmans, S., Méan, I., Xiao, T., Boukhatemi, A., Ferreira, F., Jond, L., Mutero, A., CHang, C.J., Citi, S.
Mol. Biol. Cell (2021) https://www.molbiolcell.org/doi/10.1091/mbc.E21-07-0355
WW, PH and C-terminal domains cooperate to direct the subcellular localizations of PLEKHA5, PLEKHA6 and PLEKHA7
Sluysmans, S., Méan, I., Jond, L., Citi, S.
Front. Cell Dev. Biol. (2021) https://doi.org/10.3389/fcell2021.729444
The tight junction protein cingulin regulates the vascular response to burn injury in a mouse model
Zhuravleva, K, Goertz, O., Wölkart, G., Guillemot, L., Petzelbauer P., Lehnhardt, M., Schmidt, K., Citi, S., Schossleitner, K.
Microvasc. Res. (2020) 1132: 104067.
Scaffolding proteins of vertebrate apical junctions: structure, functions and biophysics
Rouaud, F., Sluysmans, S., Flinois, A., Shah, J., Vasileva, E., Citi, S.
BBA - Biomembranes (2020) 1862, 183399. doi.org/10.1016/j.bbamem.2020.183399.
Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33
Rouaud, F., Tessaro, F., Aimaretti, L., Scapozza, L., Citi, S.
J. Biol. Chem (2020) 295 (28): 9299-9312. doi/10.1074/jbc.RA120.012987
Cell Biology: tight junctions as biomolecular condensates
Citi, S.
Current Biology (2020) https://doi.org: 10.1016/j.cub.2019.11.060
The mechanobiology of tight junctions
Citi, S.
Biophysical Reviews (2019) doi: 10.1007/s12551-019-00582-7
R40-76 binds to the alpha domain of ZO-1: role of ZO-1 (alpha+) in epithelial differentiation and mechano-sensing
Rouaud, F., Vasileva, E., Spadaro, D., Tsukita, S., Citi, S.
Tissue Barriers (2019) 10: 1969. doi: 10.1080/21688370.2019.1653748
LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-b
Rossi, M., Bucci, G., Rizzotto, D., Bordo, D., Marzi, M.J., Puppo M., Flinois A., Spdaro D., Citi, S., Emionite, L., Cilli, M., Nicassio, F., Inga A., Briata P., Gherzi, R.
Nature Comm. (2019) 10: 1969. doi: 10.1038/s41467-019-09754-1.
A dock-and-lock mechanism clusters ADAM10 at cell-cell junctions to promote alpha-toxin cytotoxicity
Shah, J., Rouaud, F., Guerrera D., Vasileva E., Popov L.,:, Kelley W.L., Rubinstein E., Carette J.E., Amieva M.R., Citi, S.
Cell Reports (2018) 25(8): 2132-2147. doi: 10.1016/j.celrep.2018.10.088.
The role of microtubules in the regulation of epithelial junctions
Vasileva, E., Citi, S.
Tissue Barriers (2018) 5: 1-20. doi: 10.1080/21688370.2018.1539596
Intestinal barriers protect against disease
Citi, S.
Science (2018) 359: 1097-1098.
1998-2002
Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.
D’Atri, F., Nadalutti, F., Citi, S.
J. Biol. Chem. (2002) 277:27757-27764.
Molecular complexity of vertebrate tight junctions.
D’Atri, F., Citi, S.
Mol. Membr. Biol. (2002) 19: 103-112.
Cingulin interacts with F-actin in vitro.
D’Atri, F., Citi, S.
FEBS Lett. (2001) 507:21-24.
Tight junction protein expression in early Xenopus development and protein interaction studies.
Citi, S., D’Atri, F., Cordenonsi, M., Cardellini, P.
In “Cell-cell interactions- A Practical Approach” (2001) T.P. Fleming, ed. (series Editor BD Hames), Oxford University Press, Oxford, UK, pp 153-176.
The cytoplasmic plaque proteins of the tight junction.
Citi, S.
In “Tight junctions” 2nd ed. (2001), M. Cereijido and J.M. Anderson, eds., pp. 231-264.
Interaction of Junctional Adhesion Molecule with the Tight Junction Components ZO-1, Cingulin, and Occludin.
Bazzoni, G., Martinez Estrada O.M., Orsenigo, F., Cordenonsi, M., Citi, S., Dejana, E.
J. Biol. Chem. (2000) 275: 20520-20526.
Tight junction biogenesis in the early Xenopus embryo.
Fesenko, I., Kurth, T., Sheth, B., Fleming, T.P., Citi, S., Hausen, P.
Mech. Dev. (2000) 96: 51-65.
Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction.
Sheth, B., Fontaine, J., Ponza, E., McCallum, A., Page A,. Citi, S., Louvard, D., Zahraoui, A., Fleming, TP.
Mech. Dev. (2000) 97:93-104.
Human and Xenopus cingulin share a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly.
Citi, S., D’Atri, F., Parry, D.A.D.
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J.Struct. Biol. (2000) 131: 135-145.
Introduction: Opening Up Tight Junctions.
Citi, S.
In Seminars in Cell and Developmental Biology, issue “Tight Junctiuns” S. Citi Ed. (2000) 11(4), pp. 277-279.
Tight junctions
Citi, S., Editor
Seminars in Cell and Developmental Biology (2000) Vol. 11, Issue 4 (pp. 277-324).
Experimental colitis increases small intestine permeability in the rat.
Fries, W., Mazzon, E., Squarzoni, S., Martin, A., Martines, D., Micali, A., Sturniolo, G. C., Citi, S., Longo, G.
Lab .Invest. (1999) 79: 49-57.
Xenopus laevis occludin: identification of in vitro phosphorylation sites by protein kinase CK2 and association with cingulin.
Cordenonsi, M., Turco, F., D’Atri, F., Hammar, E., Martinucci, G., Meggio, F., Citi, S.
Eur. J. Biochem. (1999) 264: 374-384.
Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3 and myosin.
Cordenonsi, M., D’Atri, F., Hammar, E., Parry, D.A.D., Kendrick-Jones, J., Shore, D., Citi, S.
J. Cell Biol. (1999) 147: 1569-1581.
The molecular basis for the structure, function and regulation of tight junctions.
Citi, S., Cordenonsi, M.
In: “Advances in Molecular and Cell Biology”, Vol. 28 (1999), JAI Press Inc., Stamford, CT, ed by Bittar, D.R. Garrod, A.J. North, M.A.S. Chidgey, pp. 203-233.
Cingulin.
Citi, S.
In: "Guidebook to the cytoskeletal and motor proteins" (1998), T. Kreis and R. Vale, eds, 2nd edition Oxford Univ. Press.
Tight junction proteins.
Citi, S., Cordenonsi, M. (1998).
Biochim. Biophys. Acta 1448: 1-11.
1991-1997 (Cornell University Medical College and University of Padova)
Hepatocyte tight-junctional permeability is increased in rat experimental colitis.
Lora, L., Mazzon, E., Martines, D., Fries, W., Muraca, M., Martin, A., D'Odorico, A., Naccarato, R., Citi, S.
Gastroenterology (1997) 113: 1347-1354.
Occludin dephosphorylation in early development of Xenopus laevis.
Cordenonsi, M., Mazzon, M., De Rigo, L., Baraldo, S., Meggio, F., Citi, S.
J. Cell Sci. (1997) 110: 3131-3139.
Tight junctions in early amphibian development: detection of junctional cingulin from the 2-cell stage and its localization at the boundary of distinct membrane domains in dividing blastomeres in low calcium.
Cardellini, P., Davanzo, G., Citi, S.
Dev. Dyn.207 (1996) 104-113.
Vascular smooth muscle cells of H-2Kb-tsA58 transgenic mice. Characterization of cell lines with distinct properties.
Ehler, E., Jat, P.S., Noble, M.D., Citi, S., Draeger, A.
Circulation (1995).92: 3289-3296.
Phosphorylation of the tight junction protein cingulin and the effect of protein kinase activators and inhibitors in MDCK epithelial cells.
Citi, S., Denisenko, N.
J. Cell Sci. (1995) 108: 2917-2926.
Different effects of protein kinase inhibitors on the localization of junctional proteins at cell-cell contact sites.
Denisenko, N., Burighel, P., Citi, S.
J. Cell Sci. (1994) 107, 969-981.
Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7.
Citi, S.,Volberg, T., Denisenko, N., Bershadsky, A., Geiger, B.
J. Cell Sci. (1994) 107, 683-692.
The effect of protein kinase inhibitor H-7 on the contractility, integrity and membrane anchorage of the microfilament system.
Volberg, T., Geiger, B., Citi, S., Bershadsky, A.D.
Cell Motil. Cytosk. (1994) 29, 321-338.
The molecular composition of tight junctions.
Citi, S.
In: "Molecular Mechanisms of epithelial cell junctions: from Development to Disease", S. Citi ed. (1994), RG Landes Biomedical Publishers, Austin, TX, pp 83-106.
Molecular Mechanisms of epithelial cell junctions: from Development to Disease
Citi, S.
(1994) RG Landes Biomedical Publishers, Austin, TX.
Tight junction protein cingulin is expressed by maternal and embryonic genomes during early mouse development.
Javed, Q., Fleming, T.P., Hay, M., Citi, S.
Development (1993) 117, 1135-1144.
Localization of tight junction protein cingulin is temporally and spatially regulated during early mouse development.
Fleming, T.P., Hay, M., Javed, Q., Citi, S.
Development (1993) 117, 1145-1151.
The molecular organization of tight junctions.
Citi, S.
J. Cell Biol. (1993) 121, 485-489
Cingulin.
Citi, S.
In: "Guidebook to the cytoskeletal and motor proteins", T. Kreis and R. Vale, eds. (1993), Oxford Univ. Press, pp 225-226.
Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells.
Citi, S.
-
J.Cell Biol. (1992). 117, 169-178.
Polarized functions and permeability properties of rat epididymal epithelial cells in vitro.
Byers, S.W., Citi, S., Anderson, J.M., Hoxter, B.
J. Reprod. Fertil. (1992) 95, 385-396.
Cingulin, a specific protein component of tight junctions, is expressed in normal and neoplastic human epithelial tissues.
Citi, S., Amorosi, A., Franconi, F., Giotti, A., Zampi, G.C.
Am. J. Pathol. (1991) 138, 781-789.
Localization of myosin in the cytoskeleton of brush border cells using monoclonal antibodies and confocal laser-beam scanning microscopy.
Citi, S., Kendrick-Jones, J.
Tissue & Cell (1991) 23, 789-799.
The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells.
Nigam, S., Denisenko, N., Rodriguez-Boulan, E., Citi, S.
Biochem. Biophys. Res. Commun. (1991) 181, 548-553.
Molecular approaches to study tight junctions: characterization of ZO-1 and cingulin.
Citi, S., Kendrick-Jones, J., & Shore, D.
In "Form and function in zoology", G. Lanzavecchia and R. Valvassori eds. (1991), Selected Symposia Monographs UZI 5, Mucchi, Modena, pp. 103-121.
1986-1989 (S. CITI’S PHD AND POSTOC WORK IN J. KENDRICK-JONES AND B. GEIGER’s LABS)
Cingulin: characterization and localization.
Citi, S., Sabanay, H., Kendrick-Jones, J. & Geiger, B.
J. Cell Sci. (1989) 93, 107-122.
Parallel modulation of brush border myosin conformation and enzyme activity induced by monoclonal antibodies.
Citi, S., Cross, R.A., Bagshaw, C.R., & Kendrick-Jones, J.
J. Cell Biol. (1989) 109, 549-556.
ZO-1 and cingulin: tight junction proteins with distinct identities and localizations.
Stevenson, B.R., Heintzelman, M.B., Anderson, J.M., Citi, S., Mooseker, M.S.
Am. J.Physiol. (1989) 257, Cell Physiol. 26, C621-C628.
How phosphorylation controls the self-assembly of vertebrate smooth and nonmuscle myosins.
Cross, R.A., Citi, S. & Kendrick-Jones, J.
Biochem. Soc. Trans. (1988) 16, 501-503.
Cingulin, a new peripheral component of tight junctions.
Citi, S., Sabanay, H., Jakes, R., Geiger, B. & Kendrick-Jones, J.
Nature (1988) 333, 272-276.
Brush border myosin filament assembly and interaction with actin investigated with monoclonal antibodies
Citi, S. & Kendrick-Jones, J.
J. Muscle Res. Cell Motil. (1988) 9, 306-319.
Active site trapping of nucleotide by smooth and nonmuscle myosins.
Cross, R.A., Jackson, A.P., Citi, S., Kendrick-Jones, J., & Bagshaw, C.R.
J.Mol. Biol. (1988) 203, 173-181.
Modulation of cellular morphology and locomotory activity by antibodies against myosin
Hoener, B., Citi, S., Kendrick-Jones, J., & Jockusch, B.M.
J. Cell Biol. (1988) 107, 2181-2189.
Monoclonal antibodies as probes to modulate the conformation, filament assembly and enzymatic activities of myosin.
Citi, S. & Kendrick-Jones, J.
In : Sarcomeric and non-sarcomeric muscles: basic and applied research prospects for the 90's (U. Carraro ed.) (1988), Unipress Padova, Italy, pp. 739-743.
Studies on the structure and conformation of brush border myosin using monoclonal antibodies
Citi, S. & Kendrick-Jones, J.
Eur. J. Biochem. (1987) 165, 315-325.
The polymerisation of vertebrate smooth muscle and nonmuscle myosins.
Kendrick-Jones, J., Smith, R., Craig, R., & Citi, S.
J. Mol. Biol. (1987) 198, 241-252.
The effects of light chain phosphorylation and vertebrate skeletal myosin on the stability of nonmuscle myosin filaments.
Citi, S., Smith, R., & Kendrick-Jones, J.
J. Mol. Biol. (1987) 198, 253-262.
Regulation of nonmuscle myosin structure and function
Citi, S. & Kendrick-Jones, J.
Bioessays (1987) 7, 155-159.
Regulation of "contraction" in nonmuscle cells: the role of light chain phosphorylation.
Citi, S. & Kendrick-Jones, J.
In: Advances in Myochemistry (ed. G. Benzi), J. Libbey Eurotext, Paris (1987), pp 347-348.
Regulation and organization of nonmuscle myosins
Kendrick-Jones, J., Smith, R., Citi, S.
In: "Nature and function of cytoskeletal proteins in motility and transport" (Progress in Zoology, Vol. 34, K.E. Wohlfarth-Botterman, ed. (1987)) Fischer-Verlag, Stuttgart, pp. 87-96.
Regulation in vitro of brush border myosin by light chain phosphorylation.
Citi, S., Kendrick.Jones, J.
-
J.Mol. Biol. (1986) 188, 369-382.
2003-2007
Tight junction formation in early Xenopus laevis embryos: identification and ultrastructural characterization of junctional crests and junctional vesicles.
Cardellini, P., Cirelli A., Citi, S.
Cell Tissue Res. (2007) 330:247-56.
Claudin-1 and claudin-5 expression patterns differentiate lung squamous cell carcinomas from adenocarcinomas.
Paschoud, S., Bongiovanni M., Pache J.C., Citi, S.
Mod. Pathol. (2007) 20: 947-954.
Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA.
Guillemot, L., Citi, S.
Mol. Biol. Cell (2006) 17:3569-3577.
Cingulin, a cytoskeleton-associated protein of the tight junction.
Guillemot, L., Citi, S.
In : Tight Junctions, 4th Edition (2006) (L. Gonzalez-Mariscal, ed.), Landes Bioscience Publishing.
Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition.
Aijaz, S. D’Atri, F., Citi, S., Balda, M.S., Matter, K.
Dev. Cell (2005) 8: 777-786.
Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression.
Guillemot, L., Hammar, E., Kaister, C., Ritz, J., Caille, D., Jond, L., Bauer, C., Meda, P., Citi, S.
J. Cell Sci. (2004) 117: 5245-5256.
Histone deacetylase inhibitors up-regulate the expression of tight junction proteins.
Bordin, M., D’Atri, F., Guillemot, L. , Citi, S.
Mol. Cancer Res. (2004) 2; 692-701.
What’s new in tight junctions.
Citi, S.
Cell Commun. Adhes. (2003)10: 51-54.
2008-2010
PLEKHA7 is an adherens junction protein with a tissue distribution and subcellular localization distinct from ZO-1 and E-cadherin.
Pulimeno, P., Bauer, C., Stutz, J., Citi, S.
PLoS ONE (2010) 5(8): e12207
The tight junction protein cingulin regulates gene expression and RhoA signaling.
Citi S., Paschoud S., Pulimeno P., Timolati F., De Robertis F., Jond L., Guillemot L.
Ann. NY Acad. Sci. (2009) 1165:88-98
Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression.
Paschoud, S., Citi, S.
Mol. Membr. Biol (2008) 25:1-13
Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions.
Guillemot, L., Paschoud, S., Jond, L., Foglia, A., Citi, S.
Mol. Biol. Cell (2008) 19:4442-4453
The cytoplasmic plaque of tight junctions: A scaffolding and signalling center.
Guillemot, L., Foglia, A., Paschoud, S., Pulimeno, P., Citi, S.
Biochim Biophys Acta (2008) 1778(3):601-13.
2011-2013
The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4.
Guillemot, L., Spadaro, D., Citi, S.
PLoS ONE (2013) 8 (2): e55873. doi10.1371/journal/pone.0055873
Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury.
Guillemot, L., Schneider, Y., Brun, P., Castagliuolo, I., Pizzuti, D., Martines, D., Jond, L., Bongiovanni, M., Citi, S.
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J.Cell Sci. (2012) 125: 5005-5014.
Distinct domains of paracingulin are involved in its targeting to the actin cytoskeleton and regulation of apical junction assembly.
Paschoud, S., Guillemot, L, Citi, S.
J. Biol. Chem. (2012) 287(16): 13159-13169.
The control of gene expression and cell proliferation by the epithelial apical junctional complex.
Spadaro, D., Tapia, R., Pulimeno, P., Citi, S.
Essays in Biochemistry (2012) 53:83-93.
Cingulin, paracingulin and PLEKHA7: signalling and cytoskeletal adaptors at the apical junctional complex.
Citi, S., Pulimeno P., Paschoud S.
Ann. NY Acad. Sci (2012) 1257:125-132.
Regulation of small GTPases at epithelial cell-cell junctions.
Citi, S., Spadaro, D., Schneider, Y., Stutz J. Pulimeno P.
Mol. Membr. Biol. (2011) 28:427-444.
Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions.
Paschoud, S., Yu, D., Pulimeno, P., Jond, L., Turner, J.R, Citi. S.
Mol. Membr. Biol. (2011) 28:123-135
A role for ZO-1 and PLEKHA7 in recruiting paracingulin to tight and adherens junctions of epithelial cells.
Pulimeno, P., Paschoud. S., Citi, S.
J. Biol. Chem. (2011) 286(19): 16743-50.
2014-2015
The adherens junctions control susceptibility to Staphylococcus aureus a-toxin
Popov, L.M., Marceau, C.,D., Starkl, P.M., Lumb, J.H., Shah, J., Guerrera, D., Cooper, R.L., Merakou, C., Bouley, D.M., Meng, W., , Kiyonari, H., Takeichi, M., Galli, S.J., Bagnoli, F., Citi, S., Carette, J.E., Amieva M.R.
Proc. Nat. Acad. Sci USA. (2015) 112: 14337-42. doi:10.1073/pnas.1510265112
Distinct cell-cell adhesion complexes regulate cell behavior either by engaging RNAi or via Src-p120 activity
Kourtidis A., Ngok, S.P., Pulimeno, P., Feathers, R.W., Carpio, L.R., Baker, T.R., Carr, J.M., Dachsel J.C., Perez, E.A., Storz, P., Copland, J.A., Thompson, E.A.,
Citi, S., Anastasiadis, P.Z.
Nature Cell Biol. (2015) 17: 1145-57. doi:10.1038/ncb3227
The expression of the zonula adhaerens protein PLEKHA7 is strongly decreased in high grade ductal and lobular breast carcinomas
Tille, J.C., Ho, L., Shah, J., Seyde, O., McKee, T.A., Citi, S.
PLoS One (2015) 10(8):e0135442. doi: 10.1371/journal.pone.0135442
Epithelial junctions and Rho family GTPases: the zonular signalosome
Citi, S., Guerrera, D., Spadaro, D., Shah, J.
Small GTPases (2014) DOI:10.4161/21541248.2014.97376036382. Link
Link to Research Gate full-text
ZO proteins redundantly regulate the transcription factor DbpA/ZONAB
Spadaro, D., Tapia, R., Jond, L., Sudol, M., Fanning, A.S., Citi, S.
J. Biol. Chem (2014) 289:22500-22511. Link
Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1
Ragupathy, S., Esmaeili, F., Paschoud, S., Sublet, E., Citi, S., Borchard, G.
Tissue Barriers (2014), 2: e29166. Link
MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly
Guillemot, L., Guerrera, D., Spadaro, D., Tapia, R., Jond, L., Citi, S.
Molecular Biology of the Cell (2014) mbc.E13-11-0680. Link
PLEKHA7 modulates epithelial tight junction barrier function
Paschoud, S., Jond, L., Guerrera, D., Citi, S.
Tissue Barriers (2014) 2:e28755. Link
2016-2017
Tension-dependent stretching activates ZO-1 to control the junctional localization of its interactors
Spadaro, D., Le, S., Laroche, T., Mean, I., Jond, L., Yan, J., Citi, S.
Current Biology (2017) 27:1-13; DOI: http://dx.doi.org/10.1016/j.cub.2017.11.014
Cell-specific diversity in the expression and organization of cytoplasmic plaque proteins of apical junctions
Vasileva, E., Sluysmans, S., Bochaton-Piallat, M-L., Citi, S. ,
Ann. N.Y. Acad. Sci (2017) Jun. 15; doi: 10.1111/nyas.13391. (Epub ahead of print)
The role of apical cell-cell junctions and associated cytoskeleton in mechanotransduction
Sluysmans, S., Vasileva, E., Spadaro, D., Shah, J., Rouaud, F., Citi, S. ,
Biol. Cell. (2017) Feb. 21; doi: 10.1111/boc.201600075 (Epub ahead of print). Review
Cingulin role in agonist-induced vascular endothelial permeability
Tian, Y., Gawlak, G., Tian, X., Shah, A.S., Sarich, N., Citi, S. , Birukova, A.A.
J. Biol. Chem. (2016) Sept. 02; pii: jbc.M116.720763 (Epub ahead of print)
Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells
Mangan, A. J., Sietsema, D.V., Li, D., Moore, J.K., Citi, S., Prekeris R.
Nature Comm. (2016) doi:10.1038/ncomms12426 (Epub 2016 Aug 3)
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Grete Kellenberger-Gujer: Molecular biology research pioneer
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