@Article{Organometallics_24_6104, author = {L. Vieille-Petit and G. S{\"u}ss-Fink and B. Therrien and T.R. Ward and H. Stœckli-Evans and G. Labat and L. Karmazin-Brelot and A. Neels and T. B{\"u}rgi and R.G. Finke and C.M. Hagen}, title = {{Synthesis and Characterization of Tetrahedral Ru$_3$O Clusters with Intrinsic Framework Chirality: A Chiral Probe of the Intact Cluster Catalysis Concept}}, journal= {Organometallics}, ISSN = {0276-7333}, volume= {24}, number= {25}, pages = {6104-6119}, url = {http://pubs.acs.org/doi/abs/10.1021/om050643t}, doi= {10.1021/om050643t}, abstract = {{To bring evidence for or against the hypothesis of catalytic hydrogenation by intact trinuclear arene ruthenium clusters containing an oxo cap, cationic Ru$_3$O clusters with three different arene ligands (intrinsically chiral tetrahedra) have been synthesized as racemic mixtures. By introduction of a chiral auxiliary substituent at one of the three different arene ligands, the separation of the two diastereomers was possible. The chiral Ru$_3$O framework was evidenced by X-ray crystallography, by circular dichroism in the UV and IR regions, and by chiral shift reagents in the NMR spectra. The catalytic hydrogenation of the prochiral substrate methyl 2-acetamidoacrylate using a chiral Ru$_3$O cluster showed no asymmetric induction, suggesting that the catalytically active species is not the intact Ru$_3$O cluster.}}, year = {2005} }