237. A. Alexakis, M. Vuagnoux-d'Augustin, D. Martin, S. Kehrli,
     “Formation of all-carbon chiral quaternary centers by copper catalysed asymmetric cojugate addition”
     Latvija kimijas zurnals 2007, 373-377.

In summary, the copper-​catalyzed asym. conjugate addn. of both organoaluminum and organomagnesium reagents affords a viable methodol. for the creation of all-​carbon chiral quaternary centers.  Several applications in natural product synthesis are possible, particularly when an angular Me group is needed on bicyclic systems.

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