264. S. Belot, K.A. Vogt, C. Besnard, N. Krause, A. Alexakis,
     “Enantioselective One-Pot Organocatalytic Michael Addition/Gold-Catalyzed Tandem Acetalization/Cyclization”
     Angew. Chem. Int. Ed. 2009, 48, 8923-8926.

Au-rganocatalytic reaction: A one-pot process consisting of a Michael addition to a nitroenyne and a subsequent acetalization/cyclization is reported (see scheme; TMS=trimethylsilyl), which results in the formation of nitro-substituted tetrahydrofuranyl ethers with high diastereo- and enantioselectivities. Organocatalysis and gold catalysis are compatible and complementary in a one-pot process.

DOI : 10.1002/anie.200903905 

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