Publications

 2016
Aller vers : 

 • 

"Ruthenium Lewis Acid Catalyzed Asymmetric Diels–Alder Reactions: Reverse Face Selectivity for α,β-Unsaturated Aldehydes and Ketones"
Thamapipol, S.; Ludwig, B.; Besnard, C.; Saudan, C.; Kündig, E. P.
Helv. Chim. Acta 2016, 99, 774-789 archive ouverte unige:88119

Acrolein, methacrolein, methylvinylketone, ethylvinylketone, 3-methyl-3-en-2-one, and divinylketone were coordinated to a cationic cyclopentadienyl ruthenium(II) Lewis acid incorporating the electron-poor bidentate BIPHOP–F ligand. Analysis by NOESY and ROESY NMR techniques allowed the determination of conformations of enals and enones present in solution in CD2Cl2. The results were compared to solid state structures and to the facial selectivities of catalytic asymmetric Diels–Alder reactions with cyclopentadiene. X-Ray structures of four Ru-enal and Ru-enone complexes show the α,β-unsaturated carbonyl compounds to adopt an anti-s-trans conformation. In solution, enals assume both anti-s-trans and anti-s-cis conformations. An additional conformation, syn-s-trans, is present in enone complexes. Enantioface selectivity in the cycloaddition reactions differs for enals and enones. Reaction products indicate enals to react exclusively in the anti-s-trans conformation whereas with enones, the major product results from the syn-s-trans conformation. The alkene in s-cis conformations, while present in solution, is shielded and cannot undergo cycloaddition. A syn-s-trans conformation is found in the solid state of the bulky 6,6-dimethyl cyclohexanone-Ru(II) complex. The X-ray structure of divinyl ketone is unique in that the Ru(II) center binds the enone via a η2 bond to one of the alkene moieties. In solution coordination to Ru-carbonyl oxygen is adopted. A comparison of facial preference is also made to the corresponding indenyl Lewis acids.

 • 

"Asymmetric Dearomatization with Chiral Auxiliaries and Reagents"
Kündig, E. P.
In Asymmetric Dearomatization Reactions; You, S.-L. (Ed.); Wiley-VCH Verlag: Weinheim, Germany, 2016; Chapter 2; p. 9-31

 • 

"Regioselective Synthesis and Characterization of Multinuclear Convex-bound Ruthenium-[n]Cycloparaphenylene (n=5 and 6) Complexes"
Kayahara, E.; Patel, V. K.; Mercier, A.; Kündig, E. P.; Yamago, S.
Angew. Chem. Int. Ed. 2016, 55, 302-306 archive ouverte unige:79705 texte intégral [accès restreint]

Mono- and multinuclear complexes of ruthenium and [n]cycloparaphenylene (CPP, n=5 and 6) were synthesized in excellent yields through ligand exchange of the cationic complex [(Cp)Ru(CH3CN)3](PF6) with CPP. In the multinuclear complexes, ruthenium selectively coordinated to alternate paraphenylene units to give bis- and tris-coordinated Ru complexes for [5] and [6]CPPs, respectively. Single-crystal X-ray analysis revealed the Ru was coordinated with η6-hapticity on the convex surface of CPP.

 2015
Aller vers : 

 • 

"Asymmetric bromine–lithium exchange: on the importance of both the diamine ligand and the organolithium reagent"
Praz, J.; Graff, J.; Egger, L.; Guénée, L.; Wagschal, S.; Kündig, E. P.; Alexakis, A.
Chem. Commun. 2015, 51, 16912-16915 archive ouverte unige:77587 texte intégral [accès restreint]

The asymmetric lithium-bromine exchange is described on a series of prochiral biphenyls. As in many asymmetric organolithium reactions, the chiral ligand (here a diamine) is considered as the enantiocontroling element. We demonstrate herein that the organolithium reagent, which undergoes the exchange, also plays an important role.

 • 

"Editorial"
Kündig, E. P.; Spichiger, D.
CHIMIA 2015, 69, 385

 • 

"Mononuclear Iron(III) Complexes as Functional Models of Catechol Oxidases and Catalases"
Badetti, E.; Gjoka, B.; Nagy, E. M.; Bernardinelli, G.; Kündig, P. E.; Zonta, C.; Licini, G.
Eur. J. Inorg. Chem. 2015, 3478-3484 archive ouverte unige:74455 texte intégral [accès restreint]

 2014
Aller vers : 

 • 

"Palladium-N-Heterocyclic Carbene (NHC)-Catalyzed Asymmetric Synthesis of Indolines through Regiodivergent C(sp3)—H Activation: Scope and DFT Study"
Katayev, D.; Larionov, E.; Nakanishi, M.; Besnard, C.; Kündig, E. P.
Chem. Eur. J. 2014, 20, 15021-15030 archive ouverte unige:41531 texte intégral [accès restreint]

Two bulky, chiral, monodentate N-heterocyclic carbene ligands were applied to palladium-catalyzed asymmetric C—H arylation to incorporate C(sp3)—H bond activation. Racemic mixtures of the carbamate starting materials underwent regiodivergent reactions to afford different trans-2,3-substituted indolines. Although this CAr—Calkyl coupling requires high temperatures (140–160 °C), chiral induction is high. This regiodivergent reaction, when carried out with enantiopure starting materials, can lead to single structurally different enantiopure products, depending on the catalyst chirality. The C—H activation at a tertiary center was realized only in the case of a cyclopropyl group. No C—H activation takes place alpha to a tertiary center. A detailed DFT study is included and analyses of methyl versus methylene versus methine C—H activation is used to rationalize experimentally observed regio- and enantioselectivities.

 • 

"[Cover Profile] Palladium-N-Heterocyclic Carbene (NHC)-Catalyzed Asymmetric Synthesis of Indolines through Regiodivergent C(sp3)—H Activation: Scope and DFT Study"
Katayev, D.; Larionov, E.; Nakanishi, M.; Besnard, C.; Kündig, E. P.
Chem. Eur. J. 2014, 20, 14909 archive ouverte unige:41531 texte intégral [accès libre]

Invited for the cover of this issue is the group of E. Peter Kündig at the University of Geneva. The cover illustrates the regiodivergent reaction taken by two enantiomers when subjected to a chiral Pd(N-heterocyclic carbene) catalyst. The combination of a divergent reaction with an enantioselective C—H functionalization makes for fascinating chemistry.

 • 

"Editorial"
Kündig, E. P.; Spichiger, D.
CHIMIA 2014, 68, 469

 • 

"Synthesis of 1,3-dimethyl-3-(p-tolyl)-1H-pyrrolo[3,2-c]pyridin-2(3H)-one by Cu(II)-Mediated Direct Oxidative Coupling"
Dey, C.; Kündig, E. P.
Org. Synth. 2014, 91, 221-232 archive ouverte unige:38882 texte intégral [accès libre]

 • 

"Catalysis with Complexes Containing Stereogenic Metal Centers"
Kündig, E. P.
CHIMIA 2014, 68, 312-314 archive ouverte unige:37984 texte intégral [accès restreint]

 • 

"Asymmetric Pd-NHC*-catalyzed coupling reactions"
Kündig, E. P.
Chim. Oggi / Chem. Today 2014, 32, 9-13 archive ouverte unige:36556 texte intégral [accès restreint]

 • 

"Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric SuzukiMiyaura Coupling Reactions"
Benhamou, L.; Besnard, C.; Kündig, E. P.
Organometallics 2014, 33, 260-266 archive ouverte unige:33199 texte intégral [accès restreint]

PEPPSI complexes incorporating chiral N-heterocyclic carbene (NHC) ligands based on 2,2-dimethyl-1-(o-substituted aryl)propan-1-amines were synthesized. Two complexes, with one saturated and one unsaturated NHC ligand, were structurally characterized. The chiral PEPPSI complexes were used in asymmetric Suzuki–Miyaura reactions, giving atropisomeric biaryl products in modest to good enantiomeric ratios.

 2013
Aller vers : 

 • 

"Highly Enantiomerically Enriched Planar Chiral Cyclopentadienyl(indenyl)ruthenium Complexes"
Wagschal, S.; Mercier, A.; Kündig, E. P.
Organometallics 2013, 32, 7133-7140 archive ouverte unige:31950 texte intégral [accès restreint]

The functionalization of highly enantiomerically enriched planar chiral cyclopentadienyl(4-bromoindenyl)ruthenium complexes is detailed. Lithium/bromine exchange followed by an electrophilic quench using N,N-dimethylformamide (DMF), trimethylsilyl chloride, benzaldehyde, acetone, or 1,2-diiodoethane afforded the corresponding enantiomerically enriched planar chiral complexes. Suzuki–Miyaura cross-coupling led to cyclopentadienyl(indenyl)ruthenium complexes bearing aryl and alkenyl groups in high yields. Similarly, in situ generation of the boronate intermediate using 9-MeO-9-BBN and a metalated species in the Suzuki–Miyaura reaction gave heteroaryl, alkynyl, and alkyl cyclopentadienyl(indenyl)ruthenium complexes with retention of configuration and enantiomeric excess.

 • 

"Copper(II) chloride mediated (aza)oxindole synthesis by oxidative coupling of Csp2–H and Csp3–H centers: Substrate scope and DFT study"
Dey, C.; Larionov, E.; Kündig, E. P.
Org. Biomol. Chem. 2013, 11, 6734-6743 archive ouverte unige:29897 texte intégral [accès restreint]

A CuCl2 mediated direct intramolecular oxidative coupling of Csp2−H and Csp3−H centers gives access to 3,3-disubstituted oxindoles containing aromatic, heteroaromatic and alkyl substituents as well as heteroatom at the quaternary center in good to excellent yields. The reaction is carried out in the presence of NaOtBu and CuCl2 in DMF at 110 °C. The key step of this reaction is the formation of amidyl radical by one electron oxidation of amide enolate followed by intramolecular radical cyclization reaction (homolytic aromatic substitution reaction). A detailed DFT study shows that the cyclization of amidyl radical is the rate-limiting step in the oxindole synthesis, whereas the second single electron transfer (SET) becomes the rate-determining step in the aza-oxindole formation. Computational data are in agreement with experimentally observed relative reactivity and regioselectivity.

 • 

"Synthesis of 3,3-Disubstituted Oxindoles by Palladium-Catalyzed Asymmetric Intramolecular α-Arylation of Amides: Reaction Development and Mechanistic Studies"
Katayev, D.; Jia, Y.-X.; Sharma, A. K.; Banerjee, D.; Besnard, C.; Sunoj, R. B.; Kündig, E. P.
Chem. Eur. J. 2013, 19, 11916-11927 archive ouverte unige:29561 texte intégral [accès restreint]

Palladium complexes incorporating chiral N-heterocyclic carbene (NHC) ligands catalyze the asymmetric intramolecular α-arylation of amides producing 3,3-disubstituted oxindoles. Comprehensive DFT studies have been performed to gain insight into the mechanism of this transformation. Oxidative addition is shown to be rate-determining and reductive elimination to be enantioselectivity-determining. The synthesis of seven new NHC ligands is detailed and their performance is compared. One of them, L8, containing a tBu and a 1-naphthyl group at the stereogenic centre, proved superior and was very efficient in the asymmetric synthesis of fifteen new spiro-oxindoles and three azaspiro-oxindoles often in high yields (up to 99 %) and enantioselectivities (up to 97 % ee; ee=enantiomeric excess). Three palladacycle intermediates resulting from the oxidative addition of [Pd(NHC)] into the aryl halide bond were isolated and structurally characterized (X-ray). Using these intermediates as catalysts showed alkene additives to play an important role in increasing turnover number and frequency.

 • 

"Regioselective Cyclometalation of Planar Chiral Pyridine and Oxazoline Derivatives: peri- versus ortho-C–H Functionalization"
Mercier, A.; Wagschal, S.; Guénée, L.; Besnard, C.; Kündig, E. P.
Organometallics 2013, 32, 3932-3942 archive ouverte unige:28959 texte intégral [accès restreint]

The cyclopalladation of highly enantioenriched cyclopentadienyl(indenyl)ruthenium complexes featuring pyridine or oxazoline functionalities as directing groups is detailed. Two competitive metalation sites inherent to the fused ring system were selectively activated after appropriate tuning of the reaction conditions, enabling the access to both six (peri)- and five-membered (ortho) membered chelates. A periortho isomerization was identified in the pyridine-based system, unveiling a kinetic preference for the peri-position and thermodynamic control for the ortho-cyclopalladation. In marked contrast, oxazoline derivatives incorporating a stereogenic center at C4 proved reluctant to form ortho-isomers and were exclusively converted into the corresponding peri-palladacyles at low temperatures.

 • 

"Scope and Mechanism of Asymmetric C(sp3)-H/C(Ar)-X Coupling Reactions: Computational and Experimental Study"
Larionov, E.; Nakanishi, M.; Katayev, D.; Besnard, C.; Kündig, E. P.
Chem. Sci. 2013, 4, 1995-2005 archive ouverte unige:27315 texte intégral [accès restreint]

Advances in the efficient palladium–NHC catalysed synthesis of highly enantioenriched 2,3-trans-fused and 2-alkyl indolines via asymmetric C(sp3)–H activation of an unactivated methylene/methyl group are reported. Very high asymmetric inductions (up to 99% ee) were achieved at reaction temperatures ranging from 120 to 160 °C. Factors influencing the efficiency of the reaction (halide, pseudohalide, N-protecting group) were investigated. The reaction pathway and enantioselection were probed by detailed density functional theory (DFT) calculations (M06-L functional). The combined theoretical and experimental study shows that the Pd–NHC catalysed C(sp3)–H arylation proceeds via a concerted metalation–deprotonation (CMD) mechanism. The CMD step is shown by DFT calculations and kinetic isotope effect measurements to be selectivity-determining. A good agreement between experimental enantioselectivities and calculated differences amongst diastereomeric activation barriers is observed.

 2012
Aller vers : 

 • 

"Catalytic Enantioselective Synthesis of a 3-Aryl-3-benzyloxindole (=3-Aryl-3-benzyl-1,3-dihydro-2H-indol-2-one) Exhibiting Antitumor Activity"
Katayev, D.; Kündig, E. P.
Helv. Chim. Acta 2012, 95, 2287-2295 archive ouverte unige:24335 texte intégral [accès restreint]

 • 

"Chiral N-Heterocyclic Carbene Gold Complexes: Synthesis, Properties, and Application in Asymmetric Catalysis"
Banerjee, D.; Buzas, A. K.; Besnard, C.; Kündig, E. P.
Organometallics 2012, 31, 8348-8354 archive ouverte unige:24435 texte intégral [accès restreint]

Nine new N-heterocyclic carbene gold chloride complexes (1018) were synthesized starting from bulky chiral imidazolium salts (19) developed in this laboratory. Full characterization of all complexes, including the X-ray structures of gold(I)(1,3-bis((S)-1-(2-methoxyphenyl)-2,2-dimethylpropyl)-1H-imidazol-2(3H)-ylidene) chloride (13) and gold(I)(1,3-bis((S)-2,2-dimethyl-1-(naphthalen-1-yl)propyl)-1H-imidazol-2(3H)-ylidene) chloride (16), is reported. The complexes 1018 were applied in the methoxycyclization of 1,6-enynes using AgNTf2 as an additive. Synthesis of the N-heterocyclic carbene gold triflimidate (19) was achieved by treating complex 12 with AgNTf2. The complex gold(I)(1,3-bis((R)-1-(2-methoxyphenyl)-2,2-dimethylpropyl)imidazolidin-2-ylidene)(1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methylsulfonamido) (19) was isolated and spectroscopically and structurally (X-ray) characterized.

 • 

"An expedient approach to the total synthesis of (+)-5-epi-eudesma-4(15)-ene-1β,6β-diol"
Parthasarathy, G.; Besnard, C.; Kündig, E. P.
Chem. Commun. 2012, 48, 11241-11243 archive ouverte unige:23573 texte intégral [accès restreint]

The first total synthesis of (+)-5-epi-eudesma-4(15)-ene-1β,6β-diol has been achieved in 12 steps by starting from the known (-)-cis-piperitol and using an Ireland-Claisen rearrangement of a glycolate ester and an intramolecular nitrile oxide dipolar cycloaddition as key steps.

 • 

"Desymmetrisation of meso-diols mediated by non-enzymatic acyl transfer catalysts"
Enríquez-García, Á.; Kündig, E. P.
Chem. Soc. Rev. 2012, 41, 7803-7831 archive ouverte unige:23855 texte intégral [accès restreint]

Complementary to enzymatic methods, catalytic enantioselective desymmetrisation of meso-diols (EDMD) by small molecule catalysts has emerged as a powerful tool that provides highly enantioenriched materials of considerable value in organic synthesis. This review traces the evolution of easily accessible catalysts used in the EDMD and compares their performance with the existing enzymatic methods.

 • 

"Aza-oxindole synthesis via base promoted Truce-Smiles rearrangement"
Dey, C.; Katayev, D.; Ylijoki, K.; Kündig, E. P.
Chem. Commun. 2012, 48, 10957-10959 archive ouverte unige:23521 texte intégral [accès restreint]

A novel efficient NaOtBu-mediated protocol for the synthesis of 3,3-disubstituted aza-oxindoles proceeds via a Truce–Smiles rearrangement–cyclisation pathway.

 • 

"A Synthetic and Mechanistic Investigation of the Chromium Tricarbonyl-Mediated Masamune-Bergman Cyclization. Direct Observation of a Ground-State Triplet p-Benzyne Biradical"
Ylijoki, K. E. O.; Lavy, S.; Fretzen, A.; Kündig, E. P.; Berclaz, T.; Bernardinelli, G.; Besnard, C.
Organometallics 2012, 31, 5396-5404 archive ouverte unige:22151 texte intégral [accès restreint]

A new room-temperature chromium tricarbonyl-mediated cycloaromatization of enediynes is reported. The reaction occurs with both cyclic and acyclic enediynes in the presence of [Cr(CO)36-naphthalene)] and both a coordinating solvent and a hydrogen atom source, providing chromium–arene complexes in reasonable yield and good diastereocontrol. The mechanism of the reaction has been probed through DFT computational and spectroscopic methods. These studies suggest that direct C1–C6 bond formation from an η6-enediyne complex is the lowest-energy path, forming a metal-bound p-benzyne biradical. NMR spectroscopy suggests that enediyne alkene coordination occurs in preference to alkyne coordination, forming a THF-stabilized olefin intermediate; subsequent alkyne coordination leads to cyclization. While biradical quenching occurs rapidly and primarily via the singlet biradical, the triplet state biradical is detectable by EPR spectroscopy, suggesting intersystem crossing to a triplet ground state.

 • 

"Asymmetric Pd-NHC*-catalyzed coupling reactions"
Kündig, E. P.; Jia, Y.; Katayev, D.; Nakanishi, M.
Pure Appl. Chem. 2012, 84, 1741-1748 archive ouverte unige:21935 texte intégral [accès libre]

 • 

"Asymmetric Synthesis of (+)-Vertine and (+)-Lythrine"
Chausset-Boissarie, L.; Arvai, R.; Cumming, G.; Guénée, L.; Kündig, E. P.
Org. Biomol. Chem. 2012, 10, 6473-6479 archive ouverte unige:21968 texte intégral [accès restreint]

The total syntheses of the Lythracea alkaloids (+)-vertine and (+)-lythrine are described. Enantioenriched pelletierine is used as a chiral building block and engaged into a two step pelletierine condensation leading to two quinolizidin-2-one diastereomers in a 8:1 ratio. The major product is used in the synthesis of (+)-vertine via aryl–aryl coupling and ring closing metathesis to provide a Z-alkene α to the lactone carbonyl function. The same procedure was used for (+)-lythrine after base induced epimerization of the main quinolizidin-2-one diastereomer. Alternative classical ring closure strategies like macrolactonisation or aryl–aryl coupling failed.

 • 

"Palladium-NHC Catalyzed Enantioselective Synthesis of Fused Indolines via Inert C(sp3)-H Activation"
Nakanishi, M.; Katayev, D.; Besnard, C.; Kündig, E. P.
CHIMIA 2012, 66, 241-243 archive ouverte unige:21496 texte intégral [accès restreint]

 • 

"Asymmetric C(sp3)-H/C(Ar) Coupling Reactions. Highly enantio-enriched Indolines via Regiodivergent Reaction of a Racemic Mixture"
Katayev, D.; Nakanishi, M.; Buergi, T.; Kündig, E. P.
Chem. Sci. 2012, 3, 1422-1425 archive ouverte unige:19404 texte intégral [accès restreint]

N-Aryl, N-branched alkyl carbamates react with an in situ generated chiral Pd-NHC catalyst by coupling a Pd-Ar moiety with an aliphatic C-H bond at high temperature to give enantioenriched 2-substituted and 2,3-disubstituted indolines. Prochiral precursors give single products with very high asymmetric induction. Chiral racemic precursors react in a regiodivergent reaction of a racemic mixture to yield enantioenriched indolines resulting from either methyl C-H activation or asymmetric methylene C-H activation. In favorable cases this can result in a complete separation of an enatiomeric mixture into two different highly enantioenriched indolines.

 • 

"Aza-oxindole Synthesis by Oxidative Coupling of Csp2-H and Csp3-H Centers"
Dey, C.; Kündig, E. P.
Chem. Commun. 2012, 48, 3064-3066 archive ouverte unige:18728 texte intégral [accès restreint]

A CuCl2 mediated oxidative Csp2-H and Csp3-H coupling protocol gives access to aza-oxindoles in good to excellent yield in the presence of NaOtBu as base and toluene as solvent.

 • 

"Chiral N-Heterocyclic Carbene Borane Complexes: Synthesis and Structural Analysis"
Banerjee, D.; Besnard, C.; Kündig, E. P.
Organometallics 2012, 31, 709-715 archive ouverte unige:18164 texte intégral [accès restreint]

A new family of chiral N-heterocyclic carbene borane complexes was synthesized starting from their corresponding imidazolium salts. The complexes were fully characterized. X-ray crystal structures of the complexes were obtained.

 • 

"Electronic effects in 1,3-dipolar cycloaddition reactions of N-alkyl and N-benzyl nitrones with dipolarophiles"
Bădoiu, A.; Kündig, E. P.
Org. Biomol. Chem. 2012, 10, 114-121 archive ouverte unige:17734 texte intégral [accès restreint]

1,3-Dipolar cycloadditions afforded fast access to isoxazolidines bearing N-alkyl or N-benzyl substituents. The electronic properties of the substituents in the nitrones define the activity of the dipoles and modulate diastereoselectivity in the non-catalyzed reactions. Using a chiral one-point binding ruthenium Lewis acid catalyst, products were obtained in good yields and with excellent regio-, diastereo-, and enantioselectivity.

 2011
Aller vers : 

 • 

"Functionalization of Planar Chiral Fused Arene Ruthenium Complexes: Synthesis, X-ray Structures, and Spectroscopic Characterization of Monodentate Triarylphosphines"
Buchgraber, P.; Mercier, A.; Yeo, W. C.; Besnard, C.; Kündig, E. P.
Organometallics 2011, 30, 6303-6315 archive ouverte unige:17521

The efficient functionalization of planar chiral ruthenium naphthalene- and ruthenium indenyl-scaffolds is reported. Mild reaction conditions employing microwave heating have been developed for the derivatization of sensitive cationic naphthalene ruthenium complexes. In particular, a series of novel planar chiral monodentate phosphines and their gold(I) complexes have been synthesized and fully characterized by NMR spectroscopy and X-ray crystallography. Furthermore, the electronic properties of these phosphines (L) have been evaluated via the infrared CO stretching frequencies of the corresponding Ni(CO)3(L) complexes, providing valuable insight for the design and application of these chiral ligands in asymmetric catalysis.

 • 

"Intramolecular Diels-Alder reactions using chiral ruthenium Lewis acids and application in the total synthesis of ent-ledol"
Thamapipol, S.; Kündig, E. P.
Org. Biomol. Chem. 2011, 9, 7564-7570 archive ouverte unige:17738 texte intégral [accès restreint]

One-point binding chiral ruthenium Lewis acids incorporating the C2-symmetric electron-poor bidentate phosphinite ligand BIPHOP-F and a Cp or an indenyl ‘roof’ can efficiently catalyze asymmetric intramolecular Diels-Alder reactions of trienes to form bicyclic adducts with good to excellent asymmetric induction. This reaction forms the key step in a total synthesis of ent-ledol in 96% ee. The synthesis also helps to clarify the stereochemical assignment of ledol and inconsistencies in the measured optical rotation.

 • 

"The Preparation of 2H-1,4-benzoxazin-3-(4H)-ones via Palladium-Catalyzed Intramolecular C-O Bond Formation"
Ylijoki, K. E. O.; Kündig, E. P.
Chem. Commun. 2011, 47, 10608-10610 archive ouverte unige:17024

Pd/PtBu3-catalyzed intramolecular C-O bond formation has been used to access aryl- and alkyl-substituted benzoxazinones.

 • 

"Enantiopure Ti(IV) Amino Triphenolate Complexes as NMR Chiral Solvating Agents"
Zonta, C.; Kolarovic, A.; Mba, M.; Pontini, M.; Kündig, E. P.; Licini, G.
Chirality 2011, 23, 796-800 archive ouverte unige:16948 texte intégral [accès restreint]

 • 

"Fused Indolines by Palladium-Catalyzed Asymmetric C—C Coupling Involving an Unactivated Methylene Group"
Nakanishi, M.; Katayev, D.; Besnard, C.; Kündig, E. P.
Angew. Chem. Int. Ed. 2011, 50, 7438-7441 archive ouverte unige:16744 texte intégral [accès restreint]

[ Corrigendum: Angew. Chem. Int. Ed. 2011, 50, 9775 ]

Selectivity at high temperatures: Bulky, thermally stable, chiral palladium complexes generated from N-heterocyclic carbenes (NHCs; see picture) were successfully applied to the synthesis of highly enantioenriched trans-fused indolines. Remarkably, this reaction occurs at elevated temperatures with excellent asymmetric recognition of an enantiotopic C—H bond in an unactivated methylene unit.

 • 

"[Editorial] 2011: The International Year of Chemistry"
Kündig, E. P.; Viehweger, K. H.; Eggersdorfer, M.
CHIMIA 2011, 65, 200-201 archive ouverte unige:16320

 • 

"Asymmetric Intramolecular Diels-Alder Reactions of Trienals Catalyzed by Chiral Ruthenium Lewis Acids"
Thamapipol, S.; Kündig, E. P.
CHIMIA 2011, 65, 268-270 archive ouverte unige:16319 texte intégral [accès restreint]

 • 

"Highly efficient desymmetrisation of a tricarbonylchromium 1,4-dibromonaphthalene complex by asymmetric Suzuki–Miyaura coupling"
Urbaneja, X.; Mercier, A.; Besnard, C.; Kündig, E. P.
Chem. Commun. 2011, 47, 3739-3741 archive ouverte unige:14937 texte intégral [accès restreint]

Access to planar chiral complexes has been sought by catalytic desymmetrisation of a prochiral complex via asymmetric Suzuki-Miyaura cross-coupling. High selectivities of up to 98% ee were achieved using a bulky chiral palladium catalyst.

 2010
Aller vers : 

 • 

"Chiral Ruthenium Lewis Acid Catalyzed Intramolecular Diels-Alder Reactions"
Thamapipol, S.; Bernardinelli, G.; Besnard, C.; Kündig, E. P.
Org. Lett. 2010, 12, 5604-5607 archive ouverte unige:12856 texte intégral [accès restreint]

Single point binding ruthenium Lewis acid catalysts [Ru(acetone)(S,S)-BIPHOP-F)Cp][SbF6] ((S,S)-1b) and [Ru(acetone)(S,S)-BIPHOP-F)(indenyl)][SbF6] ((S,S)-1c) efficiently catalyze intramolecular Diels-Alder (IMDA) reactions under mild conditions to afford the endo cycloaddition products as the major product in excellent yields with high diastereo- and enantioselectivities.

 • 

"Efficient Enantioselective Syntheses of Sertraline, 2-Epicatalponol and Catalponol from Tetralin-1,4-dione"
Enriquez Garcia, A.; Ouizem, S.; Cheng, X.; Romanens, P.; Kündig, E. P.
Adv. Synth. Catal. 2010, 352, 2306-2314 archive ouverte unige:11952 texte intégral [accès restreint]

Tetralin-1,4-dione, the stable tautomer of dihydroxynaphthalene, was reduced with catecholborane in the presence of 3,3-diphenyl-1-butyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole as catalyst to give enantiomerically highly enriched 4-hydroxy-1-tetralone (99% ee) in an efficient one-pot procedure. The R-enantiomer provided a rapid access to sertraline while the S-enantiomer was converted into 2-epicatalponol and catalponol. A more selective enantioselective route to the antithermitic catalponol made use of the planar chiral tricarbonylchromium complex of hydroxytetralone. Its precursor chromium(tricarbonyl)[η6-(1-4,4a,8a)-tetralin-5,8-dione] was obtained via direct complexation of 1,4-dihydroxynaphthalene using chromium(tricarbonyl)- tris(ammonia) and boron trifluoride etherate as source of the chromium(tricarbonyl) fragment. Enolate prenylation was best carried out in the presence of a tetraamine ligand. Complete inversion of the stereogenic center bearing the prenyl group of the initially obtained tetralone complex was achieved via enolate formation followed by protonation.

 

 • 

"Total synthesis of (±)-Vertine with Z-selective RCM as a key step"
Chausset-Boissarie, L.; Àrvai, R.; Cumming, G. R.; Besnard, C.; Kündig, E. P.
Chem. Commun. 2010, 46, 6264-6266 archive ouverte unige:11663 texte intégral [accès restreint]

A concise total synthesis of the strained pentacyclic alkaloid (±)-Vertine has been achieved in eleven steps with the key steps being pelletierine condensation, Suzuki-Miyaura coupling, and ring-closing metathesis.

 • 

"Ruthenium Lewis Acid Catalyzed Asymmetric 1,3-Dipolar Cycloadditions between N-Methylnitrones and Enals"
Bădoiu, A.; Bernardinelli, G.; Kündig, E. P.
Synthesis 2010, 2207-2212 archive ouverte unige:8295 texte intégral [accès restreint]

 • 

"New Chiral N-Heterocyclic Carbene Ligands in Palladium-Catalyzed α-Arylations of Amides: Conformational Locking through Allylic Strain as a Device for Stereocontrol"
Jia, Y.-X.; Katayev, D.; Bernardinelli, G.; Seidel, T. M.; Kündig, E. P.
Chem. Eur. J. 2010, 16, 6300-6309 archive ouverte unige:6695 texte intégral [accès restreint]

New Enders/Herrmann-type chiral N-heterocyclic carbene (NHC) ligands have been developed and applied in asymmetric palladium-catalyzed intramolecular α-arylations of amides. The best ligands feature the bulky tert-butyl group and ortho-substituted aryl groups at the stereogenic centers. Aryl bromides readily react at room temperature and aryl chlorides at 50 °C. The highly enantiomerically enriched (up to 96 % ee) 3-alkyl-3-aryloxindole products were obtained in generally high yields (>95 %) except in cases of steric congestion. The critical roles both of the bulky alkyl group and of the ortho-aryl substituent at the stereogenic center of the ligand were revealed in the crystal structure of a [Pd(η3-allyl)(NHC-L*)(I)] complex. The ligand aryl location and orientation is fixed by conformational locking that minimizes A1,3-strain and enables optimal transfer of chiral information.

 • 

"Asymmetric Catalytic Hydrogenolysis of Aryl—Halide Bonds in Fused Arene Chromium and Ruthenium Complexes"
Mercier, A.; Urbaneja, X.; Yeo, W. C.; Chaudhuri, P. D.; Cumming, G. R.; House, D.; Bernardinelli, G.; Kündig, E. P.
Chem. Eur. J. 2010, 16, 6285-6299 archive ouverte unige:6696 texte intégral [accès restreint]

Access to highly enantioenriched planar chiral [Cr(5-bromonaphthalene)(CO)3] (6), [Ru(η5-C5R5)(5-bromonaphthalene)][PF6] (42) and [Ru(η5-C5R5)(4-bromoindene)] (44) was sought using asymmetric hydrogenolysis of [Cr(5,8-dibromonaphthalene)(CO)3] (5), [Ru(η5-C5R5)(5,8-dibromonaphthalene)] (39) and [Ru(η5-C5R5)(4,7-dibromoindene)] (40), respectively. Initial efforts focused on the chromium complex 5. Pd0 catalysts with dimethoxyethane as the solvent and LiBH4 or NaBH3CN as a hydride source worked best. Nineteen chiral bidentate phosphorus ligands were screened in this reaction. Asymmetric induction was low to modest with product ee′s in the range of 4 to 52 % and yields of 6 of up to 70 %. Chiral phosphoramidite ligands proved superior and a bulky ligand derived from a Whitesell amine and 3,3′-diphenyl-binaphtol afforded 6 with an ee of 97 %. The high enantioselectivity is largely due to the initial desymmetrization reaction though kinetic resolution also plays an important role as shown by the determination of a selectivity factor s=8.5 at -10 °C. Initially high ligand loadings (4 equiv/Pd) were necessary to achieve good asymmetric induction. This could be traced to the trapping of the chiral ligand by borane formed in the reaction. Addition of 1,4-diazabicyclo[2.2.2]octane (DABCO) suppressed this, and its addition led to the use of Pd and chiral ligand in a 1:1.2 ratio. Asymmetric hydrogenolysis of cationic dibromonaphthalene and neutral dibromoindenyl complexes of Ru cyclopentadienyl complexes was investigated and afforded the following results: [RuCp(5-bromonaphthalene)][PF6] (39 a; 75 %, 90 % ee), [RuCp*(5-bromonaphthalene)] [PF6] (39 b; 88 %, 99 % ee), [RuCp(4-bromoindenyl)] (44 a; 72 %, 96 % ee), and [RuCp*(4-bromoindenyl)] (44 b; 62 %, 68 % ee).

 • 

"An Efficient Entry to Planar Chiral Organometallic Complexes via Pd-Catalyzed Asymmetric Hydrogenolysis"
Mercier, A.; Yeo, W. C.; Urbaneja, X.; Kündig, E. P.
CHIMIA 2010, 64, 177-179 archive ouverte unige:6361 texte intégral [accès libre]

 • 

"Synthesis of 3-hydroxyoxindoles by Pd-catalysed intramolecular nucleophilic addition of aryl halides to α-ketoamides"
Jia, Y.-X.; Katayev, D.; Kündig, E. P.
Chem. Commun. 2010, 46, 130-132 archive ouverte unige:4865

Pd/PtBu3-catalysed intramolecular nucleophilic addition of aryl halides to α-ketoamides in the presence of nBuOH and base has been realized with high yields, providing a new, direct, and efficient synthetic strategy to obtain 3-hydroxyoxindoles.

 • 

"Asymmetric ruthenium-catalyzed 1,4-additions of aryl thiols to enones"
Bădoiu, A.; Bernardinelli, G.; Besnard, C.; Kündig, E. P.
Org. Biomol. Chem. 2010, 8, 193-200 archive ouverte unige:4864

Well defined, stable, one-point binding ruthenium complexes 1 and 2 selectively bind and activate α,β-unsaturated carbonyl compounds for cycloaddition reactions. These mild Lewis acids catalyze asymmetric 1,4-addition reactions of aryl thiols to enones with product selectivities up to 87% ee. 31P NMR experiments provide an insight into the intricate equilibria governing the reaction mechanism. The absolute configuration of the major products indicates enones to react in the syn-s-trans orientation. Models based on X-ray structures of the Ru complexes can be used to rationalize selectivity.

 2009
Aller vers : 

 • 

"Organic Chemistry à la Genevoise"
Mazet, C.; Zumbuehl, A.; Jeannerat, D.; Mareda, J.; Alexakis, A.; Kündig, E. P.; Lacour, J.; Matile, S.
CHIMIA 2009, 63, 816-821 archive ouverte unige:7946 texte intégral [accès restreint]

 • 

"Synthesis of highly enantiomerically enriched planar chiral ruthenium complexes via Pd-catalysed asymmetric hydrogenolysis"
Mercier, A.; Yeo, W. C.; Chou, J.; Chaudhuri, P. D.; Bernardinelli, G.; Kündig, E. P.
Chem. Commun. 2009, 5227-5229 archive ouverte unige:7030 texte intégral [accès restreint]

Key elements in this communication are a very efficient microwave synthesis of [RuCp(naphthalene)][PF6], the precursor of [RuCp(CH3CN)3][PF6], and a Pd-catalysed asymmetric hydrogenolysis to afford planar chiral ruthenium complexes with high levels of enantioselectivity using a bulky chiral phosphoramidite ligand.

 • 

"Iron- and Ruthenium-Lewis Acid Catalyzed Asymmetric 1,3-Dipolar Cycloaddition Reactions between Enals and Diaryl Nitrones"
Bădoiu, A.; Bernardinelli, G.; Mareda, J.; Kündig, E. P.; Viton, F.
Chem. Asian J. 2009, 4, 1021-1022 archive ouverte unige:8456 texte intégral [accès restreint]

[ Cet article corrige : Chem. Asian J. 2008, 3(8-9), 1298-1311 ]

 • 

"Oxindole Synthesis by direct coupling of C(sp2)—H and C(sp3)—H Centers"
Jia, Y.-X.; Kündig, E. P.
Angew. Chem. Int. Ed. 2009, 48, 1636-1639 archive ouverte unige:7026 texte intégral [accès restreint]

[ Selectionné pour Synfacts 2009, 484 ]

An sp2/sp3 get-together: A novel and efficient method can be used to synthesize 3,3-disubstitued oxindoles by the direct intramolecular oxidative coupling of an aryl Csp2—H and a Csp3—H center (see scheme, DMF=N,N-dimethylformamide).

 2008
Aller vers : 

 • 

"Diastereoselective and enantioselective reduction of tetralin- 1,4-dione"
Kündig, E. P.; Enriquez-Garcia, A.
Beilstein J. Org. Chem. 2008, 4, No. 37 archive ouverte unige:7935 texte intégral [accès restreint]

 • 

"Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis"
Jia, Y.-X.; Hillgren, J. M.; Watson, E. L.; Marsden, S. P.; Kündig, E. P.
Chem. Commun. 2008, 4040-4042 archive ouverte unige:7029 texte intégral [accès restreint]

[ Sélectionné comme hot paper ]

The Pd-catalysed asymmetric intramolecular α-arylation of amideenolates containing heteroatom substituents gives chiral 3-alkoxy or 3-aminooxindoles in high yield and with enantioselectivities up to 97% ee when a new chiral N-heterocyclic carbene ligand is used.

 • 

"Truncated Cinchona alkaloids as catalysts in enantioselective monobenzoylation of meso-1,2-diols"
Kündig, E. P.; Enriquez-Garcia, A.; Lomberget, T.; Perez Garcia, P.; Romanens, P.
Chem. Commun. 2008, 3519-3521 archive ouverte unige:6659 texte intégral [accès libre]

[ Sélectionné pour Synfacts 2008, 990 ]

Readily synthesised quincorine and quincoridine derived chiral diamines efficiently catalyse the asymmetric monobenzoylation of cyclic and acyclic meso-1,2-diols.

 • 

"Iron- and Ruthenium-Lewis Acid Catalyzed Asymmetric 1,3-Dipolar Cycloaddition Reactions between Enals and Diaryl Nitrones"
Bădoiu, A.; Bernardinelli, G.; Mareda, J.; Kündig, E. P.; Viton, F.
Chem. Asian J. 2008, 3, 1298-1311 archive ouverte unige:7027 texte intégral [accès restreint]

 • 

"Asymmetric Lewis Acid-Catalyzed 1,3-Dipolar Cycloadditions"
Bădoiu, A.; Brinkmann, Y.; Viton, F.; Kündig, E. P.
Pure Appl. Chem. 2008, 80, 1013-1018 archive ouverte unige:8006 texte intégral [accès restreint]

 • 

"Synthesis of a Bicyclo[8.3.1]enediyne via Chromium-Mediated Dearomatization of 2,6-Bis(trimethylsilyl)anisole"
Lavy, S.; Pérez-Luna, A.; Kündig, E. P.
Synlett 2008, 2621-2624 archive ouverte unige:7961 texte intégral [accès restreint]

 • 

"C3 Vanadium(V) Amine Triphenolate Complexes: Vanadium Haloperoxidase Structural and Functional Models"
Mba, M.; Pontini, M.; Lovat, S.; Zonta, C.; Bernardinelli, G.; Kündig, E. P.; Licini, G.
Inorg. Chem. 2008, 47, 8616-8618 archive ouverte unige:7037 texte intégral [accès restreint]

 • 

"Chiral Electron-poor P-Ligands in Metal-based Lewis Acids"
Kündig, E. P.; Bădoiu, A.
In Phosphorus Ligands in Asymmetric Catalysis; Börner, A. (Ed.); Wiley-VCH: Weinheim, 2008; Part II, Chap. 4.4.2; p. 437 archive ouverte unige:8371

 2007
Aller vers : 

 • 

"Bulky Chiral Carbene Ligands and Their Application in the Palladium-Catalyzed Asymmetric Intramolecular α-Arylation of Amides"
Kündig, E. P.; Seidel, T. M.; Jia, Y.-X.; Bernardinelli, G.
Angew. Chem. Int. Ed. 2007, 46, 8484-8487 archive ouverte unige:6900 texte intégral [accès restreint]

Bring on the big cats: New, C2-symmetric bulky N-heterocyclic carbene ligands bring major improvements in the palladium-catalyzed asymmetric intramolecular α-arylation of amides to give oxindoles (see picture, dba=trans,trans-dibenzylideneacetone), which are formed in high yield and excellent enantiomeric purity.

 • 

"Ruthenium–Lewis Acid Catalyzed Asymmetric Diels–Alder Reactions between Dienes and α,β-Unsaturated Ketones"
Rickerby, J.; Vallet, M.; Bernardinelli, G.; Viton, F.; Kündig, E. P.
Chem. Eur. J. 2007, 13, 3354-3368 archive ouverte unige:7731 texte intégral [accès restreint]

The complex [Ru(Cp)(R,R-BIPHOP-F)(acetone)][SbF6], (R,R)-1 a, was used as catalyst for asymmetric Diels–Alder reactions between dienes (cyclopentadiene, methylcyclopentadiene, isoprene, 2,3-dimethylbutadiene) and α,β-unsaturated ketones (methyl vinyl ketone (MVK), ethyl vinyl ketone, divinyl ketone, α-bromovinyl methyl ketone and α-chlorovinyl methyl ketone). The cycloaddition products were obtained in yields of 50–90 % and with enantioselectivities up to 96 % ee. Ethyl vinyl ketone, divinyl ketone and the halogenated vinyl ketones worked best and their reactions with acyclic dienes consistently provided products with >90 % ee. α-Chlorovinyl methyl ketone performed better than α-bromovinyl methyl ketone. The reaction also provided a [4.3.1]bicyclic ring system in 95 % ee through an intramolecular cycloaddition reaction. Crystal structure determinations of [Ru(Cp)((S,S)-BIPHOP-F)(mvk)][SbF6], (S,S)-1 b, and [Ru(Cp)((R,R)-Me4BIPHOP-F)(acrolein)][SbF6], (R,R)-2 b, provided the basis for a rationalization of the asymmetric induction.

 • 

"Photoinitiation of Acrylate Polymerization with (Arene)chromium Complexes"
Kündig, E. P.; Xu, L.-H.; Kondratenko, M.; Cunningham Jr., A. F.; Kunz, M.
Eur. J. Inorg. Chem. 2007, 2934-2943 archive ouverte unige:7744 texte intégral [accès restreint]

 • 

"Tetrahydronaphthalene-1,4-dione and its Chromiumtricarbonyl Complex"
Garcia, Á. E.; Kündig, E. P.; Lomberget, T.; Bragg, R.; Poulard, C.; Bernardinelli, G.
CHIMIA 2007, 61, 169-171 archive ouverte unige:7737 texte intégral [accès restreint]

 • 

"Chiral ruthenium Lewis acid-catalyzed nitrile oxide cycloadditions"
Brinkmann, Y.; Madhushaw, R. J.; Jazzar, R.; Bernardinelli, G.; Kündig, E. P.
Tetrahedron 2007, 63, 8413-8419 archive ouverte unige:7057 texte intégral [accès restreint]

 • 

"Stereoselective dimerization of racemic C3-symmetric Ti(IV) amine triphenolate complexes"
Bernardinelli, G.; Seidel, T. M.; Kündig, E. P.; Prins, L. J.; Kolarvoic, A.; Mba, M.; Pontini, M.; Licini, G.
Dalton Trans. 2007, 1573-1576 archive ouverte unige:6911 texte intégral [accès restreint]

 2006
Aller vers : 

 • 

"Highly Enantiomerically Enriched Planar Chiral Naphtalene Tricarbonylchromium Complexes"
Cumming, G. R.; Bernardinelli, G.; Kündig, E. P.
Chem. Asian J. 2006, 1, 459-468 archive ouverte unige:6904 texte intégral [accès restreint]

 • 

"Synthesis of 4,5-trans-Substitued Cyclohexanones"
Kündig, E. P.; Sau, M.; Perez-Luna, A.
Synlett 2006, 2114-2118 archive ouverte unige:6936 texte intégral [accès restreint]

 • 

"Special topic issue on the theme of organometallics in organic synthesis - Preface"
Alexakis, A.; Kündig, E. P.
Pure Appl. Chem. 2006, 78, vi archive ouverte unige:8134

 • 

"The Future of Organic Synthesis"
Kündig, E. P.
Science 2006, 314, 430-431 archive ouverte unige:7756 texte intégral [accès restreint]

 • 

"1st European Chemistry Congress: Where Science Stands"
Lehn, J.-M.; Kündig, E. P.
Nachr. Chem. 2006, 54, 121-123 archive ouverte unige:7932 texte intégral [accès restreint]

 • 

"Synthesis of [6,n] cis-fused ring compounds via Cr-mediated dearomatisation-ring-closing metathesis"
Kündig, E. P.; Bellido, A.; Kaliappan, K. P.; Pape, A. R.; Radix, S.
Org. Biomol. Chem. 2006, 4, 342-351 archive ouverte unige:6927 texte intégral [accès restreint]

 • 

"Catalytic Enantioselective Hydrogenolysis of [Cr(CO)3(5,8-Dibromonaphthalene)]"
Kündig, E. P.; Chaudhuri, P. D.; House, D.; Bernardinelli, G.
Angew. Chem. Int. Ed. 2006, 45, 1092-1095 archive ouverte unige:6898 texte intégral [accès restreint]

 • 

"Rediscovery, Isolation, and Asymmetric Reduction of 1,2,3,4-Tetrahydronaphthalene-1,4-dione and Studies of Its [Cr(CO)3] Complex"
Kündig, E. P.; Enríquez García, A.; Lomberget, T.; Bernardinelli, G.
Angew. Chem. Int. Ed. 2006, 45, 98-101 archive ouverte unige:6896 texte intégral [accès restreint]

 2005
Aller vers : 

 • 

"Chromium-Mediated Dearomatization: Application to the Total Synthesis of Racemic 15-Acetoxytubipofuran and Asymmetric Synthesis of Both Enantiomers"
Kündig, E. P.; Laxmisha, M. S.; Cannas, R.; Tchertchian, S.; Ronggang, L.
Helv. Chim. Acta 2005, 88, 1063-1080 archive ouverte unige:7837 texte intégral [accès restreint]

 2004
Aller vers : 

 • 

"Synthesis of Substituted Arene Molybdenum Complexes by Arene Exchange"
Kündig, E. P.; Fabritius, C.-H.; Grossheimann, G.; Romanens, P.; Butenschön, H.; Wey, H. G.
Organometallics 2004, 23, 3741-3744 archive ouverte unige:6943 texte intégral [accès restreint]

 • 

"Toward an Understanding of the Anion Effect in CpRu-Based Diels-Alder Catalysts via PGSE-NMR Measurements"
Anil Kumar, P. G.; Pregosin, P. S.; Vallet, M.; Bernardinelli, G.; Jazzar, R. F.; Viton, F.; Kündig, E. P.
Organometallics 2004, 23, 5410-5418 archive ouverte unige:6944 texte intégral [accès restreint]

 • 

"Pd-catalysed one-pot coupling of allylamines, activated alkenes, and unsaturated halides (or triflate): an atom efficient synthesis of highly functionalized pyrrolidines"
Martinon, L.; Azoulay, S.; Monteiro, N.; Kündig, E. P.; Balme, G.
J. Organomet. Chem. 2004, 689, 3831-3836 archive ouverte unige:7064 texte intégral [accès restreint]

 • 

"Desymmetrization of a meso-diol complex derived from [Cr(CO)36-5,8-naphthoquinone)]: use of new diamine acylation catalysts"
Kündig, E. P.; Lomberget, T.; Bragg, R.; Poulard, C.; Bernardinelli, G.
Chem. Commun. 2004, 1548-1549 archive ouverte unige:6967 texte intégral [accès restreint]

 • 

"Efficient Synthesis of Tris(acetonitrile)-(η5-cyclopentadienyl)-ruthenium(II) Hexafluorophosphate via Ruthenocene"
Kündig, E. P.; Monnier, F. R.
Adv. Synth. Catal. 2004, 346, 901-904 archive ouverte unige:7887 texte intégral [accès restreint]

 • 

"Transition Metal Arene π-Complexes in Organic Synthesis and Catalysis"
Kündig, E. P. (Ed.);
Topics in Organometallic Chemistry, Volume 7; Springer: Berlin, 2004 archive ouverte unige:8368

 • 

"Ruthenium Lewis Acid Catalyzed Reactions"
Jazzar, R.; Kündig, E. P.
In Ruthenium in Organic Synthesis; Murahashi, S.-I. (Ed.); Wiley-VCH: Weinheim, 2004; chap. 10; p. 257-276 archive ouverte unige:8369

 • 

"Asymmetric Syntheses of 2-(1-Aminoethyl)phenols"
Kündig, E. P.; Botuha, C.; Lemercier, G.; Romanens, P.; Saudan, L.; Thibault, S.
Helv. Chim. Acta 2004, 87, 561-579 archive ouverte unige:7833 texte intégral [accès restreint]

 • 

"Synthesis of cationic (arene)IronCp complexes via arene exchange"
Kündig, E. P.; Jeger, P.; Bernardinelli, G.
Inorg. Chim. Acta 2004, 357, 1909-1919 archive ouverte unige:7921 texte intégral [accès restreint]

 • 

"[CpRu((R)-Binop-F)(H2O)][SbF6], a New Fluxional Chiral Lewis Acid Catalyst: Synthesis, Dynamic NMR, Asymmetric Catalysis, and Theoretical Studies"
Alezra, V.; Bernardinelli, G.; Corminboeuf, C.; Frey, U.; Kündig, E. P.; Merbach, A. E.; Saudan, C. M.; Viton, F.; Weber, J.
J. Am. Chem. Soc. 2004, 126, 4843-4853 archive ouverte unige:3518 texte intégral [accès libre]

 • 

"Stereoselective chromium- and molybdenum-mediated transformations of arenes"
Kündig, E. P.; Cannas, R.; Fabritus, C.-H.; Grossheimann, G.; Kandratenko, M.; Laxmisha, M.; Pache, S.; Ratni, H.; Robvieux, F.; Romanens, P.; Tchertchian, S.
Pure Appl. Chem. 2004, 76, 689-695 archive ouverte unige:8000 texte intégral [accès restreint]

 2003
Aller vers : 

 • 

"Conformational Studies of ortho-Substituted Benzaldehyde Chromium Tricarbonyl Complexes"
Pache, S.; Romanens, P.; Kündig, E. P.
Organometallics 2003, 22, 377-380 archive ouverte unige:6941 texte intégral [accès restreint]

 • 

"Chromium-Mediated Asymmetric Synthesis of Both Enantiomers of Acetoxytubipofuran"
Kündig, E. P.; Cannas, R.; Laxmisha, M.; Ronggang, L.; Tchertchian, S.
J. Am. Chem. Soc. 2003, 125, 5642-5643 archive ouverte unige:6986 texte intégral [accès restreint]

 • 

"Efficient Access to Fused Ring Compounds via Dearomatization/Ring-Closing Metathesis"
Kündig, E. P.; Bellido, A.; Kaliappan, K. P.; Pape, A. R.; Radix, S.
Synlett 2003, 2407-2409 archive ouverte unige:6201

 • 

"New Chromium Enolates"
Kündig, E. P.; Bernardinelli, G.; Kondratenko, M.; Robvieux, F.; Romanens, P.
Helv. Chim. Acta 2003, 86, 4169-4184 archive ouverte unige:7831 texte intégral [accès restreint]

 2002
Aller vers : 

 • 

"Product Class 4: Arene Organometallic Complexes of Chromium, Molybdenum, and Tungsten"
Kündig, E. P.; Pache, S. H.
In Category 1: Organometallics; Imamoto, T. (Ed.); Science of Synthesis, Vol. 2; Thieme: Stuttgart/New York, 2002; p. 155-228 archive ouverte unige:8367

 • 

"Iron and Ruthenium Lewis Acid Catalyzed Asymmetric 1,3-Dipolar Cycloaddition Reactions between Nitrones and Enals"
Viton, F.; Bernardinelli, G.; Kündig, E. P.
J. Am. Chem. Soc. 2002, 1224, 4968-4969 archive ouverte unige:6985 texte intégral [accès restreint]

 • 

"Towards the total synthesis (+)-vertin with planar arene chromium complexes"
Krishna Mohan, S.; Kündig, E. P.
Oriental J. Chem. 2002, 18, 179-182 archive ouverte unige:6255

Corrigendum: The retrosynthetic analysis and all reaction schemes in the above-mentioned paper have been copied from the 2001 Ph.D. thesis of Hassen Ratni (University of Geneva, Thesis No 3249). None of the reactions reported originates from Dr. S. Krishna Mohan. The paper was submitted without my knowledge and the rightful co-author is Hassen Ratni (now at Roche Pharma, Basel) and not S. Krishna Mohan. I also wish to express my deep concern about the committed scientific misconduct. ]

 • 

"trans-Addition of Two Carbon Substituents across a Benzene Double Bond in [(η6-Benzene)Mo(CO)3]"
Kündig, E. P.; Fabritius, C.-H.; Grossheimann, G.; Robvieux, F.; Romanens, P.; Bernardinelli, G.
Angew. Chem. Int. Ed. 2002, 41, 4577-4579 archive ouverte unige:7820 texte intégral [accès restreint]

 • 

"New Chromium Carbonyl Catalysts for [6+2] Cycloaddition Reactions"
Kündig, E. P.; Robvieux, F.; Kondratenko, M.
Synthesis 2002, 2053-2056 archive ouverte unige:6610

 2001
Aller vers : 

 • 

"Chiral Cyclopentadienyl-Iron and -Ruthenium Lewis Acids Containing the Electron-Poor BIPHOP-F Ligand: a Comparison as Catalysts in an Asymmetric Diels-Alder Reaction"
Kündig, E. P.; Saudan, C. M.; Viton, F.
Adv. Synth. Catal. 2001, 343, 51-56 archive ouverte unige:7886 texte intégral [accès restreint]

 • 

"Intramolecular Pd-Catalyzed Carbocyclization, Heck Reactions, and Aryl-Radical Cyclizations with Planar Chiral Arene Tricarbonyl Chromium Complexes"
Kündig, E. P.; Ratni, H.; Crousse, B.; Bernardinelli, G.
J. Org. Chem. 2001, 66, 1852-1860 archive ouverte unige:6947 texte intégral [accès restreint]

 • 

"[(Indenyl)Ru(biphop-F)]+: A Lewis Acid Catalyst That Controls both the Diene and the Dienophile Facial Selectivity in Diels-Alder Reactions"
Kündig, E. P.; Saudan, C. M.; Alezra, V.; Viton, F.; Bernardinelli, G.
Angew. Chem. Int. Ed. 2001, 40, 4481-4485 archive ouverte unige:7817 texte intégral [accès restreint]

 • 

"Diastereoselective Transformation of Arenes into Highly Enantiomerically Enriched Substituted Cyclohexadienes"
Bernardinelli, G.; Gillet, S.; Kündig, E. P.; Liu, R.; Ripa, A.; Saudan, L.
Synthesis 2001, 2040-2054 archive ouverte unige:8457

 • 

"Chiral Bidentate (Phosphinophenyl)benzoxazine Ligands in Asymmetric Catalysis"
Bernardinelli, G. H.; Kündig, E. P.; Meier, P.; Pfaltz, A.; Radkowski, K.; Zimmermann, N.; Neuburger-Zehnder, M.
Helv. Chim. Acta 2001, 84, 3233-3246 archive ouverte unige:7828 texte intégral [accès restreint]

 • 

"Dicarbonylbis(1,4-difluoro-2,3,5,6-tetramethyl-1,4-diboracyclohexa-2,5-diene)molybdenum"
Anderson, K. M.; Kündig, E. P.; Norman, N. C.; Orpen, A. G.; Pardoe, J. A. J.; Smith, D. W.; Timms, P. L.
Acta Crystallogr. Sect. E: Struct. Rep. Online 2001, E57, m419-m420 archive ouverte unige:7906 texte intégral [accès restreint]

 2000
Aller vers : 

 • 

"Diastereoselective synthesis of (5R,7R)- and (5R,7S)-5,7-dimethyl-6,7-dihydro-5H-dibenz[c,e]azepines"
Saudan, L. A.; Bernardinelli, G.; Kündig, E. P.
Synlett 2000, 483-486 archive ouverte unige:6200

 • 

"[n-Bu4N][Δ-TRISPHAT] Salt. Efficient NMR Chiral Shift Reagent for Neutral Planar Chiral Tricarbonyl Chromium Complexes"
Ratni, H.; Jodry, J. J.; Lacour, J.; Kündig, E. P.
Organometallics 2000, 19, 3997-3999 archive ouverte unige:6938 texte intégral [accès restreint]

 • 

"Transition-Metal-Mediated Dearomatization Reactions"
Pape, A. R.; Kaliappan, K. P.; Kündig, E. P.
Chem. Rev. 2000, 100, 2917-2940 archive ouverte unige:7911 texte intégral [accès restreint]

 • 

"Asymmetric Synthesis of Planar Chiral (Arene)tricarbonylchromium Complexes via Enantioselective Deprotonation by Conformationally Constrained Chiral Lithium-Amide Bases"
Pache, S.; Botuha, C.; Franz, R.; Kündig, E. P.; Einhorn, J.
Helv. Chim. Acta 2000, 83, 2436-2451 archive ouverte unige:7827 texte intégral [accès restreint]

 • 

"Transition Metal Lewis Acids: From Vanadium to Platinum"
Kündig, E. P.; Saudan, C. M.
In Lewis Acids in Organic Synthesis, Vol. 2; Yamamoto, H. (Ed.); Wiley-VCH: Weinheim, 2000; p. 597-652 archive ouverte unige:8366

 • 

"α-t-Butyl- and α-i-Propyl-ortho-hydroxybenzylamines: Racemic Synthesis/Resolution and Asymmetric Synthesis"
Bernardinelli, G.; Fernandez, D.; Gosmini, R.; Meier, P.; Ripa, A.; Schüpfer, P.; Treptow, B.; Kündig, E. P.
Chirality 2000, 12, 529-539 archive ouverte unige:7777 texte intégral [accès restreint]

 1999
Aller vers : 

 • 

"From Planar Chiral o-Chloro- and o-Iodo Benzaldehyde Tricarbonyl Chromium Complexes to Enantiopure Fused Hydroisoquinolines and Hydroquinolines"
Ratni, H.; Crousse, B.; Kündig, E. P.
Synlett 1999, 626-628 archive ouverte unige:6199

 • 

"Synthesis of (-)-Lasubine(I) via a Planar Chiral [(η6-Arene)Cr(CO)3] Complex"
Ratni, H.; Kündig, E. P.
Org. Lett. 1999, 1, 1997-1999 archive ouverte unige:6952 texte intégral [accès restreint]

[ Additions et corrections dans Org. Lett. 2000, 2, 1983-1984 ]

 • 

"Enantioselective Deprotonation/Electrophile Addition Reactions of Tricarbonyl(phenyl carbamate)chromium Complexes"
Quattropani, A.; Bernardinelli, G.; Kündig, E. P.
Helv. Chim. Acta 1999, 82, 90-104 archive ouverte unige:7826 texte intégral [accès restreint]

 • 

"A Stable and Recoverable Chiral Ru Lewis Acid: Synthesis, Asymmetric Diels-Alder Catalysis and Structure of the Lewis Acid Methacrolein Complex"
Kündig, E. P.; Saudan, C. M.; Bernardinelli, G.
Angew. Chem. Int. Ed. 1999, 38, 1219-1223 archive ouverte unige:7812 texte intégral [accès restreint]

 • 

"Synthesis of New Chiral Bidentate (Phosphinophenyl)benzoxazine P,N-Ligands"
Kündig, E. P.; Meier, P.
Helv. Chim. Acta 1999, 82, 1360-1370 archive ouverte unige:7825 texte intégral [accès restreint]

 1998
Aller vers : 

 • 

"Acrylate-Assisted Arene-Chromium Bond Cleavage: Generation of a [Cr(CO)2] Fragment under Mild Conditions"
Kündig, E. P.; Kondratenko, M.; Romanens, P.
Angew. Chem. Int. Ed. 1998, 37, 3146-3148 archive ouverte unige:7811 texte intégral [accès restreint]

 • 

"Arene Chromium Complexes: Heterocyclic Chiral Auxiliaries and Synthetic Targets"
Kündig, E. P.; Bernardinelli, G.; Beruben, D.; Crousse, B.; Fretzen, A.; Ratni, H.; Schnell, B.; Xu, L.-H.
ECHET98: Electronic Conference on Heterocyclic Chemistry 1998, 77-90 archive ouverte unige:8258

 • 

"1,2-Disubstituted [(η6-Arene)Cr(CO)3] Complexes by Sequential Nucleophilic Addition/endo-Hydride Abstraction"
Fretzen, A.; Ripa, A.; Liu, R.; Bernardinelli, G.; Kündig, E. P.
Chem. Eur. J. 1998, 4, 215-259 archive ouverte unige:7764 texte intégral [accès restreint]

 • 

"A New Chiral Ligand for the Fe-Lewis Acid Catalysed Asymmetric Diels-Alder Reaction"
Bruin, M. E.; Kündig, E. P.
Chem. Commun. 1998, 2635-2636 archive ouverte unige:6203

 • 

"Intramolecular Pd Catalyzed Carbocyclization Reactions with Planar Chiral Arene Tricarbonyl Chromium Complexes"
Crousse, B.; Xu, L.-H.; Bernardinelli, G.; Kündig, E. P.
Synlett 1998, 658-660 archive ouverte unige:6198

 1997
Aller vers : 

 • 

"Asymmetric Propargylation/Allylation/Pauson-Khand Cyclization of a Planar Chiral Anisole Tricarbonylchromium Complex"
Quattropani, A.; Anderson, G.; Bernardinelli, G.; Kündig, E. P.
J. Am. Chem. Soc. 1997, 119, 4773-4774 archive ouverte unige:7854 texte intégral [accès restreint]

 • 

"Chiral auxiliaries, ligands and arene chromium complexes"
Kündig, E. P.; Amurrio, D.; Anderson, G.; Beruben, D.; Khan, K.; Ripa, A.; Ronggang, L.
Pure Appl. Chem. 1997, 69, 543-546 archive ouverte unige:7998 texte intégral [accès restreint]

 • 

"Enantioselective Synthesis of Planar Chiral [Cr(η6-Arene)(CO)3] Complexes via Nucleophilic Addition/Hydride Abstraction"
Fretzen, A.; Kündig, E. P.
Helv. Chim. Acta 1997, 80, 2023-2026 archive ouverte unige:7824 texte intégral [accès restreint]

 1996
Aller vers : 

 • 

"Chiral CO-emulating ligands: From arene chromium chemistry to enantioselective catalysis"
Kündig, E. P.; Quattropani, A.; Inage, M.; Ripa, A.; Dupré, C.; Cunningham Jr., A. F.; Bourdin, B.
Pure Appl. Chem. 1996, 68, 97-104 archive ouverte unige:7996 texte intégral [accès restreint]

 • 

"Planar Chiral Tricarbonylchromium Complexes: Asymmetric Aza-Diels-Alder Reaction and Intramolecular Radical Cyclization to Indolizidines and Quinolizidines"
Kündig, E. P.; Xu, L.-H.; Romanens, P.; Bernardinelli, G.
Synlett 1996, 270-272 archive ouverte unige:6197

 • 

"Chiral Tricarbonyl(η6-cyclobutabenzene)chromium Complexes. Diastereoselective Synthesis and Use in Asymmetric Cycloaddition Reactions"
Kündig, E. P.; Leresche, J.; Saudan, L.; Bernardinelli, G.
Tetrahedron 1996, 52, 7363-7378 archive ouverte unige:6969 texte intégral [accès restreint]

 • 

"Intramolecular Vinyl Radical Cyclization Reactions of Cyclohexadienes Derived from Sequential Additions to (Arene)(tricarbonyl)chromium Complexes"
Beruben, D.; Kündig, E. P.
Helv. Chim. Acta 1996, 79, 1533-1536 archive ouverte unige:7822 texte intégral [accès restreint]

 • 

"Asymmetric Addition of Organolithium Reagents to Prochiral Arene Tricarbonylchromium Complexes"
Amurrio, D.; Khan, K.; Kündig, E. P.
J. Org. Chem. 1996, 61, 2258-2259 archive ouverte unige:6946 texte intégral [accès restreint]

 1995
Aller vers : 

 • 

"Asymmetric synthesis and catalysis with chiral arene and cyclopentadienyl complexes"
Kündig, E. P.; Leresche, J.; Xu, L.-H.; Ripa, A.; Liu, R.; Dupré, C.; Bourdin, B.
Stereoselective Reactions of Metal-Activated Molecules; Werner, H.; Sundermeyer, J. (Eds.); Vieweg: Wiesbaden, 1995; p. 125-136 archive ouverte unige:8370

[ Proceedings of the Second Symposium Held in Würzburg, September 21-23, 1994. (Book review in: Appl. Organomet. Chem. 1998,12, 145) ]

 • 

"1,2-Asymmetric Induction in Radical Reactions of β-Amino Acid Derivatives"
Kündig, E. P.; Xu, L.-H.; Romanens, P.
Tetrahedron Lett. 1995, 36, 4047-4050 archive ouverte unige:6998 texte intégral [accès restreint]

 • 

"Additions of Carbanions to a Cationic Cyclopentadienyl(naphthalene)iron Complex"
Kündig, E. P.; Jeger, P.; Bernardinelli, G.
Angew. Chem. Int. Ed. Engl. 1995, 34, 2161-2163 archive ouverte unige:6663

 1994
Aller vers : 

 • 

"Efficient Synthesis of Methyl 2-(tert-Butyl)acrylate and Analogous Esters"
Xu, L.-H.; Kündig, E. P.
Helv. Chim. Acta 1994, 77, 1480-1484 archive ouverte unige:6227

 • 

"New C2-Chiral Bidentate Ligands Bridging the Gap between Donor Phosphine and Acceptor Carbonyl Ligands"
Kündig, E. P.; Dupré, C.; Bourdin, B.; Cunningham Jr., A.; Pons, D.
Helv. Chim. Acta 1994, 77, 421-428 archive ouverte unige:6229

 • 

"Arenes to Substituted Cyclohexadienes: Nucleophile/Electrophile Additions across an Arene Double Bond"
Kündig, E. P.; Ripa, A.; Liu, R.; Bernardinelli, G.
Org. Chem. 1994, 59, 4773-4783 archive ouverte unige:7931 texte intégral [accès restreint]

 • 

"Planar chiral arene tricarbonylchromium complexes via enantioselective deprotonation/electrophile addition reactions"
Kündig, E. P.; Quattropani, A.
Tetrahedron Lett. 1994, 35, 3497-3500 archive ouverte unige:6669

 • 

"Planar Chiral Arylaldehydeimine Tricarbonylchromium Complexes in the Asymmetric Baylis-Hillman Coupling Reaction"
Kündig, E. P.; Xu, L.-H.; Schnell, B.
Synlett 1994, 413-414 archive ouverte unige:6196

 • 

"Asymmetric Diels-Alder reactions catalyzed by a chiral iron Lewis acid"
Kündig, E. P.; Bourdin, B.; Bernardinelli, G.
Angew. Chem. Int. Ed. Engl. 1994, 33, 1856-1858 archive ouverte unige:6664

 • 

"Quantum Chemical Investigation of the Structure and Reactivity of Indole Derivatives of Tricarbonylchromium(0)"
Furet, E.; Savary, F.; Weber, J.; Kündig, E. P.
Helv. Chim. Acta 1994, 77, 2117-2124 archive ouverte unige:2884

 1993
Aller vers : 

 • 

"Synthesis, Properties, and Reactions with C-Nucleophiles of (Phenyloxazoline)-, (Phenylmethanimine)-, and (Benzaldehyde Hydrazone)tricarbonylchromium(0) Complexes"
Kündig, E. P.; Ripa, A.; Liu, R.; Amurrio, D.; Bernardinelli, G.
Organometallics 1993, 12, 3724-3737 archive ouverte unige:7773 texte intégral [accès restreint]

 • 

"Agostic Complexes via Nucleophile Addition/Protonation Reactions of (η6-Benzene)tris(trifluorophosphine)chromium"
Kündig, E. P.; Amurrio, D.; Bernardinelli, G.; Chowdhury, R.
Organometallics 1993, 12, 4275-4277 archive ouverte unige:7774 texte intégral [accès restreint]

 • 

"Generation of and diastereoselective cycloaddition reactions to ortho-quinodimethane tricarbonylchromium intermediates"
Kündig, E. P.; Leresche, J.
Tetrahedron 1993, 49, 5599-5615 archive ouverte unige:6609

 • 

"Highly diastereoselective coupling reactions between chiral benzaldehyde tricarbonylchromium complexes and activated double bonds"
Kündig, E. P.; Xu, L.-H.; Romanens, P.; Bernardinelli, G.
Tetrahedron Lett. 1993, 34, 7049-7052 archive ouverte unige:6607

 1992
Aller vers : 

 • 

"Synthesis and reactivity of naphthalene sandwich complexes of molybdenum. X-ray structure of [Mo(η6-naphthalene){P(OMe)3}3] and [Mo(H)(η6-naphthalene){P(OMe)3}3][BF4]"
Do Thi, N. P.; Spichiger, S.; Paglia, P.; Bernardinelli, G.; Kündig, E. P.; Timms, P. L.
Helv. Chim. Acta 1992, 75, 2593-2607 archive ouverte unige:6224

 • 

"A New Asymmetric Synthesis of Tricarbonylchromium Complexes of ortho-Substituted Benzaldehydes"
Kündig, E. P.; Liu, R.; Ripa, A.
Helv. Chim. Acta 1992, 75, 2657-2660 archive ouverte unige:6225

 • 

"Diastereoselective Synthesis of Substituted Cyclohexadienes from Enantiomerically Pure Tricarbonyl(2-pheny1-4, 5-dihydrooxazole)chromium Complexes"
Kündig, E. P.; Ripa, A.; Bernardinelli, G.
Angew. Chem. Int. Ed. Engl. 1992, 31, 1071-1073 archive ouverte unige:6183

 • 

"Experimental and Theoretical Investigation of Asymmetric Induction in the Synthesis of Disubstituted Cyclohexadienes via Chiral Benzene Chromium Complexes"
Bernardinelli, G.; Cunningham, A.; Dupre, C.; Kündig, E. P.; Stussi, D.; Weber, J.
CHIMIA 1992, 46, 126-129 archive ouverte unige:2932 texte intégral [accès restreint]

 • 

"Development and Applications of an Extended-Hückel-Based Reactivity Index for Organometallic Complexes"
Weber, J.; Stussi, D.; Fluekiger, P.; Morgantini, P.-Y.; Kündig, E. P.
Comments Inorg. Chem. 1992, 14, 27-62 archive ouverte unige:2915

 1991
Aller vers : 

 • 

"Nucleophile / Electrophile Double Additions to (1-Methoxynaphthalene)tricarbonyl­chromium(0). Application in a Formal Synthesis of the Aklavinone AB Ring"
Kündig, E. P.; Inage, M.; Bernardinelli, G.
Organometallics 1991, 10, 2921-2930 archive ouverte unige:7772 texte intégral [accès restreint]

 • 

"Tricarbonylchromium Phenyloxazoline and -Imine Complexes: Highly Regioselective ortho-Additions of Carbon Nucleophiles"
Kündig, E. P.; Amurrio, D.; Liu, R.; Ripa, A.
Synlett 1991, 657-658 archive ouverte unige:6195

 • 

"Stereocontrolled and Regiocontrolled Addition of Two or Three Carbon Substituents across an Arene Double Bond of Phenyloxazolines and Phenylmethanimines Coordinated to the Tricarbonylchromium Group"
Kündig, E. P.; Bernardinelli, G.; Liu, R.; Ripa, A.
J. Am. Chem. Soc. 1991, 113, 9676-9677 archive ouverte unige:7846 texte intégral [accès restreint]

 • 

"Addition of Carbon Nucleophiles to Tricarbonylchromium Complexes of 1,2-Dihydrocyclobutabenzene, Indane, 1,2,3,4-Tetrahydronaphthalene and ortho-Xylene"
Kündig, E. P.; Grivet, C.; Wenger, E.; Bernardinelli, G.; Williams, A. F.
Helv. Chim. Acta 1991, 74, 2009-2023 archive ouverte unige:6223

 • 

"Generation of and cycloaddition to an enantiomerically pure α-oxy-ortho-quinodimethane-tricarbonylchromium complex intermediate"
Kündig, E. P.; Bernardinelli, G.; Leresche, J.
J. Chem. Soc., Chem. Commun. 1991, 1713-1715 archive ouverte unige:7799 texte intégral [accès restreint]

 1990
Aller vers : 

 • 

"Modeling of organometallic reactivity using a combination of extended Hueckel and molecular graphics techniques"
Morgantini, P. Y.; Fluekiger, P.; Weber, J.; Kündig, E. P.
Stud. Phys. Theor. Chem. 1990, 71, 313-321 archive ouverte unige:3052

 • 

"Intramolecular Interconversion of syn- and anti-Tricarbonyl(1-ethoxy-1,2-dihydrocyclobutabenzene)chromium. Trapping of the ortho-Quinodimethane Intermediate"
Kündig, E. P.; Bernardinelli, G.; Leresche, J.; Romanens, P.
Angew. Chem. Int. Ed. Engl. 1990, 29, 407-409 archive ouverte unige:6666

 • 

"trans-Disubstituted Cyclohexadienes via Sequential Addition of a Carbon Nucleophile and an Electrophile to (η6-Benzene)tricarbonylchromium: Scope of Carbon Electrophiles"
Kündig, E. P.; Cunningham Jr., A. F.; Paglia, P.; Simmons, D. P.; Bernardinelli, G.
Helv. Chim. Acta 1990, 73, 386-404 archive ouverte unige:6222

 • 

"Bicyclo[4.2.0]octa-1,3,5-triene: 2-Mono- and 2,5-Disubstituted Derivatives via Highly Regioselective Lithiation of Its Cr(CO)3 Complex and via Reductive Silylation/Oxidation"
Kündig, E. P.; Perret, C.; Rudolph, B.
Helv. Chim. Acta 1990, 73, 1970-1979 archive ouverte unige:6221

 1989
Aller vers : 

 • 

"Indanetricarbonylchromium: The Effect of 1-Syn- and 1-Anti Substituents on the Regioselectivity of Nucleophilic Addition. Crystal Structures of 1-Syn- and 1-Anti-methoxyindanetricarbonylchromium"
Ohlsson, B.; Ullenius, C.; Jagner, S.; Grivet, C.; Wenger, E.; Kündig, E. P.
J. Organomet. Chem. 1989, 365, 243-267 archive ouverte unige:6187

 • 

"Thermodynamic Control in the Addition of Carbanions to Arenetricarbonylchromium Complexes"
Kündig, E. P.; Desobry, V.; Simmons, D. P.; Wenger, E.
J. Am. Chem. Soc. 1989, 111, 1804-1814 archive ouverte unige:7845 texte intégral [accès restreint]

 1988
Aller vers : 

 • 

"1.3-Benzodithiole Tetraoxide (BDT) as a CH22- Synthon"
Kündig, E. P.; Cunningham Jr., A. F.
Tetrahedron 1988, 44, 6855-6860 archive ouverte unige:6205

 • 

"An Efficient Synthesis of Both Enantiomers of trans-1,2-Cyclopentanediol and Their Conversion to Two Novel Bidentate Phosphite and Fluorophosphinite Ligands"
Cunningham Jr., A. F.; Kündig, E. P.
J. Org. Chem. 1988, 53, 1823-1825 archive ouverte unige:7776 texte intégral [accès restreint]

 1987
Aller vers : 

 • 

"Selective Reactions on Arene Chromium Complexes"
Kündig, E. P.; Do Thi, N. P.; Paglia, P.; Simmons, D. P.; Spichiger, S.; Wenger, E.
Organometallics in Organic Synthesis; de Meijere, A.; tom Dieck, H. E. (Eds.); Springer Verlag: Berlin, 1987; p. 265-276 archive ouverte unige:8365

 • 

"Reversibility of the Lithiation of η6 Naphthalenetricarbonylchromium"
Kündig, E. P.; Grivet, C.; Spichiger, S.
J. Organomet. Chem. 1987, 332, C13-C16 archive ouverte unige:6186

 • 

"Regioselective Electrophilic Substitution via Lithiation and Intramolecular Arene Exchange (Haptotropic Rearrangement) in (Naphthalene)tricarbonylchromium"
Kündig, E. P.; Desobry, V.; Grivet, C.; Rudolph, B.; Spichiger, S.
Organometallics 1987, 6, 1173-1180 archive ouverte unige:7775 texte intégral [accès restreint]

 1985
Aller vers : 

 • 

"Arene Transformation Reactions via Chromium Complexes"
Kündig, E. P.; Uemura, M.
Kagakudojin 1985, 105, 175 archive ouverte unige:6252

 • 

"The Electronic Structures of Bis(η6-benzene)- and Bis(η6-naphthalene)chromium(0)"
Weber, J.; Kündig, E. P.; Goursot, A.; Penigault, E.
Can. J. Chem. 1985, 63, 1734-1740 archive ouverte unige:7884 texte intégral [accès restreint]

 • 

"Naphthalene Complexes. V. Arene Exchange Reactions in Naphthalenechromium Complexes"
Kündig, E. P.; Perret, C.; Spichiger, S.; Bernardinelli, G.
J. Organomet. Chem. 1985, 286, 183-200 archive ouverte unige:6185

 • 

"Recent Advances in Arene Transformation Reactions via Chromium Complexes"
Kündig, E. P.
Pure Appl. Chem. 1985, 57, 1855-1864 archive ouverte unige:7997 texte intégral [accès restreint]

 1984
Aller vers : 

 • 

"The Synthesis and Structure of Pentacarbonyl (5H-dipyrrolo[1,2-c: 2',1'-e]imidazol-5-yl)manganese"
Burger, U.; Perret, C.; Bernardinelli, G.; Kündig, E. P.
Helv. Chim. Acta 1984, 67, 2063-2067 archive ouverte unige:6216

 1983
Aller vers : 

 • 

"Stopping a Chromium Carousel: X-Ray Crystallographic and Variable-Temperature 13C-NMR Studies on Dicarbonyl(hexaethylbenzene)thiocarbonylchromium(0) and Related Complexes"
McGlinchey, M. J.; Fletcher, J. L.; Sayer, B. G.; Bougeard, P.; Faggiani, R.; Lock, C. J.; Bain, A. D.; Rodger, C.; Kündig, E. P.; Astruc, D.; Hamon, J.-R.; Lemaux, P.; Top, S.; Jaouen, G.
J. Chem. Soc., Chem. Commun. 1983, 634-636 archive ouverte unige:7797 texte intégral [accès restreint]

 • 

"Reaction of Manganese Atoms with Cyclic Dienes and Cycloheptatriene: Crystal Structure of Carbonylbis(1-4-η-cyclohexa-1,3-diene)manganese"
Kündig, E. P.; Timms, P. L.; Kelly, B. A.; Woodward, P.
J. Chem. Soc., Dalton Trans. 1983, 901-904 archive ouverte unige:7925 texte intégral [accès restreint]

 • 

"The Transformation of Arenes into Acetyl Dienes via Nucleophilic Addition to Arene-Cr(CO)3 Complexes and Trapping with MeI"
Kündig, E. P.; Simmons, D. P.
J. Chem. Soc., Chem. Commun. 1983, 1320-1322 archive ouverte unige:7796 texte intégral [accès restreint]

 • 

"Regioselectivity in the Addition of Carbanions to (1,4-Dimethoxynaphthalene)tricarbonylchromium. A New Entry into Anthracyclinone Synthesis"
Kündig, E. P.; Desobry, V.; Simmons, D. P.
J. Am. Chem. Soc. 1983, 105, 6962-6963 archive ouverte unige:7840 texte intégral [accès restreint]

 1982
Aller vers : 

 • 

"Efficient Preparation of Allylic Grignard Reagents Using Slurries of Precondensed Magnesium"
Oppolzer, W.; Kündig, E. P.; Bishop, P. M.; Perret, C.
Tetrahedron Lett. 1982, 23, 3901-3904 archive ouverte unige:6236

 1981
Aller vers : 

 • 

"Low Temperature Grignard Reactions with Pure Mg Slurries. Trapping of Cyclopropylmethyl and Benzocyclobutenylmethyl Grignard Reagents with CO2"
Kündig, E. P.; Perret, C.
Helv. Chim. Acta 1981, 64, 2606-2613 archive ouverte unige:6213

 • 

"Naphthalene Complexes. Part 2. A 13C-NMR Study of Naphthalene Chromium Complexes. Correlation with Reactivity: Nucleophilic Aromatic Substitution Reactions"
Desobry, V.; Kündig, E. P.
Helv. Chim. Acta 1981, 64, 1288-1297 archive ouverte unige:6213

 1980
Aller vers : 

 • 

"Naphthalene Complexes. Part 1. Metal Vapour Preparation of Bis(η6-naphthalene)chromium(0) and its Arene Replacement Reactions"
Kündig, E. P.; Timms, P. L.
J. Chem. Soc., Dalton Trans. 1980, 991-995 archive ouverte unige:7924 texte intégral [accès restreint]

 1978
Aller vers : 

 • 

"Preparation of Diarenemetal Complexes by Potassium Atom Reduction"
Hawker, P. N.; Kündig, E. P.; Timms, P. L.
J. Chem. Soc., Chem. Commun. 1978, 730-731 archive ouverte unige:7795 texte intégral [accès restreint]

 1977
Aller vers : 

 • 

"Metal Atom Preparation and Ligand Displacement Reactions of Bisnaphthalene Chromium and Related Compounds"
Kündig, E. P.; Timms, P. L.
J. Chem. Soc., Chem. Commun. 1977, 912-913 archive ouverte unige:7794 texte intégral [accès restreint]

 • 

"Divanadium"
Ford, T. A.; Huber, H.; Klotzbücher, W.; Kündig, E. P.; Moskovits, M.; Ozin, G. A.
J. Chem. Phys. 1977, 66, 524-530 archive ouverte unige:6250

 1975
Aller vers : 

 • 

"Matrix Synthesis and Characterization of Dichromium"
Kündig, E. P.; Moskovits, M.; Ozin, G. A.
Nature 1975, 254, 503-504 archive ouverte unige:6253

 • 

"Transition Metal Atoms in the Synthesis of Binuclear Complexes"
Kündig, E. P.; Moskovits, M.; Ozin, G. A.
Angew. Chem. Int. Ed. Engl. 1975, 14, 292-303 archive ouverte unige:6207

 • 

"Reactions of Monoatomic and Diatomic Manganese with Carbon Monoxide. Matrix Infrared Spectroscopic Evidence for Pentacarbonylmanganese Mn(CO)5 and the Binuclear Carbonyls Mn2(CO)n (where n = 1 or 2)"
Huber, H.; Kündig, E. P.; Ozin, G. A.; Poë, A. J.
J. Am. Chem. Soc. 1975, 97, 308-314 archive ouverte unige:7868 texte intégral [accès restreint]

 • 

"Binary Copper Carbonyls. Synthesis and Characterization of Cu(CO)3, Cu(CO)2, Cu(CO) and Cu2(CO)6"
Huber, H.; Kündig, E. P.; Moskovits, M.; Ozin, G. A.
J. Am. Chem. Soc. 1975, 97, 2097-2106 archive ouverte unige:7867 texte intégral [accès restreint]

 • 

"Chemical Synthesis Using Metal Atoms. Matrix Infrared, Raman, Ultraviolet-Visible, and Electron Spin Resonance Studies of the Binary Carbonyls of Cobalt, Co(CO)n (where n = 1-4) and the Distortion Problem in Co(CO)4"
Hanlan, L. A.; Huber, H.; Kündig, E. P.; McGarvey, B. R.; Ozin, G. A.
J. Am. Chem. Soc. 1975, 97, 7054-7068 archive ouverte unige:7869 texte intégral [accès restreint]

 1974
Aller vers : 

 • 

"Trigonal Bipyramidal Chromium Pentacarbonyl and Its Implications to Structure and Bonding Considerations of Pentacarbonyls and Pentacarbonyl Anions"
Kündig, E. P.; Ozin, G. A.
J. Am. Chem. Soc. 1974, 96, 3820-3823 archive ouverte unige:7865 texte intégral [accès restreint]

 • 

"Matrix Infrared and Laser Raman Spectra, Molecular Structures and Normal Coordinate Analyses of Germanium Difluoride, Monomer GeF2, and Dimer (GeF2)2"
Huber, H.; Kündig, E. P.; Ozin, G. A.; Vander Voet, A.
Can. J. Chem. 1974, 52, 95-99 archive ouverte unige:7883 texte intégral [accès restreint]

 • 

"Synthesis and Infrared Spectroscopic Detection of Rhenium Pentacarbonyl"
Huber, H.; Kündig, E. P.; Ozin, G. A.
J. Am. Chem. Soc. 1974, 96, 5585-5586 archive ouverte unige:7866 texte intégral [accès restreint]

 1973
Aller vers : 

 • 

"Binary Mixed Dinitrogen-Carbonyl Complexes of Nickel(0); Ni(N2)m(CO)4-m where m = 1-3"
Kündig, E. P.; Moskovits, M.; Ozin, G. A.
Can. J. Chem. 1973, 51, 2737-2746 archive ouverte unige:7882 texte intégral [accès restreint]

 • 

"Binary Transition Metal Dinitrogen Complexes. Part II. Matrix Infrared and Raman Spectra, Structure and Bonding of Pt(N2)n where n = 1-3"
Kündig, E. P.; Moskovits, M.; Ozin, G. A.
Can. J. Chem. 1973, 51, 2710-2721 archive ouverte unige:7881 texte intégral [accès restreint]

 • 

"Binary Carbonyls of Platinum, Pt(CO)n (Where n = 1-4). A Comparative Study of the Chemical and Physical Properties of M(CO)n (where M = Ni, Pd or Pt; n = 1-4)"
Kündig, E. P.; McIntosh, D.; Moskovits, M.; Ozin, G. A.
J. Am. Chem. Soc. 1973, 95, 7234-7241 archive ouverte unige:7864 texte intégral [accès restreint]

 • 

"Binary Transition Metal Dinitrogen Complexes. I. Matrix Infrared and Raman Spectra, Structure, and Bonding of Ni(N2)n and Pd(N2)m (n = 1-4 and m = 1-3)"
Huber, H.; Kündig, E. P.; Moskovits, M.; Ozin, G. A.
J. Am. Chem. Soc. 1973, 95, 332-344 archive ouverte unige:7863 texte intégral [accès restreint]

 1972
Aller vers : 

 • 

"Matrix Infrared and Raman Spectroscopic Evidence for Pd(N2)3 in Solid Nitrogen"
Ozin, G. A.; Kündig, P.; Huber, H.; Moskovits, M.
Can. J. Chem. 1972, 50, 2385-2387 archive ouverte unige:7879 texte intégral [accès restreint]

 • 

"Matrix isolation laser Raman spectroscopy: a Raman and infrared spectral study including Raman polarisation data for the co-condensation reaction of Pd Spectroscopic and structural data for the new tetra-carbonyls Pd(CO)4 AND Pt(CO)4"
Kündig, P.; Moskovits, M.; Ozin, G. A.
J. Mol. Struct. 1972, 14, 137-144 archive ouverte unige:6241

 • 

"Intermediate Binary Carbonyls of Palladium Pd(CO)n (where n = 1-3). Preparation, Identification and Diffusion Kinetics by Matrix Isolation Infrared Spectroscopy"
Kündig, E. P.; Moskovits, M.; Ozin, G. A.
Can. J. Chem. 1972, 50, 3587-3593 archive ouverte unige:7880 texte intégral [accès restreint]

 • 

"Tetracarbonyls of Palladium and Platinum in Low Temperature Matrices"
Huber, H.; Moskovits, M.; Kündig, P.; Ozin, G. A.
Nature-Physical Science 1972, 235, 98-100 archive ouverte unige:6254