139. “Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis”
     Y.-X. Jia, J.M. Hillgren, E.L. Watson, S.P. Marsden, E.P. Kündig,
     Chem. Commun. 2008, 4040-4042.
     [ Sélectionné comme hot paper]

The Pd-catalysed asymmetric intramolecular α-arylation of amideenolates containing heteroatom substituents gives chiral 3-alkoxy or 3-aminooxindoles in high yield and with enantioselectivities up to 97% ee when a new chiral N-heterocyclic carbene ligand is used.

DOI : 10.1039/b810858g 

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