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Our research focuses on design, synthesis and study of organic functional systems; emphasis is on conceptual innovation - integrating unorthodox interactions and addressing lessons from and challenges in nature - for broad applications such as cellular uptake, fluorescent probes or catalysis.  Click here for application information.

Latest Publications


Humeniuk, H. V.; Rosspeintner, A.; Licari, G.; Kilin, V.; Bonacina, L.; Vauthey, E.; Sakai, N.; Matile, S. “White-Fluorescent Dual-Emission Mechanosensitive Membrane Probes that Function by Bending Rather than Twisting”, Angew. Chem. Int. Ed. 2018, in press.

López-Andarias, J.; Bauzá, A.; Sakai, N.; Frontera, A.; Matile, S. “Remote Control of Anion-π Catalysis on Fullerene-Centered Catalytic Triads”, Angew. Chem. Int. Ed. 2018, in press.

Okamoto, Y.; Kojima, R.; Schwizer, F.; Bartolami, E.; Heinisch, T.; Matile, S.; Fussenegger, M.; Ward, T. R. “A Cell-Penetrating Artificial Metalloenzyme Regulates a Gene Switch in a Designer Mammalian Cell”, Nat. Commun. 2018, 9, 1943.

What's New

April: Watch Eline in action.

March 2018: Press release on the discovery of pnictogen-bonding catalysis.

July: Quantitative: Sebastian Benz (chalcogen-bonding catalysis) and Le Liu (anion-π catalysis) returned with a poster award each from ESOC-20, the European Symposium on Organic Chemistry, in Cologne, Germany.

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