Other Functions

Transport. Most current topics of interest have emerged from our long-standing interest in new structural motifs that can transport ions across lipid bilayer membranes. Our main contributions to this collection are rigid-rod molecules as reliable transmembrane scaffolds, as well as artificial β-barrels. However, there are also π-stack architectures, push-pull rods, cation-π slides, anion-π slides, polyion-counterion transporters, and so on.
Introductory Reviews: Acc. Chem. Res. 2005; 2008; 2013.

Photosystems. Studies on artificial photosystems also started in lipid bilayer membranes. To increase complexity, however, we soon moved on and became interested to develop synthetic methods to build, directly on solid surfaces, multicomponent architectures of highest possible sophistication with highest possible precision. Realized methods include zipper assembly, SOSIP (self-organizing surface-initiated polymerization), templated self-sorting (TSS) and templated stack exchange (TSE), and the third orthogonal dynamic covalent bond has been discovered. The highlight among realized architectures are co-axial channels with oriented antiparallel gradients to drive electrons and holes far apart before they can recombine, a bit like in biological photosystems (so-called OMARG SHJs).

 

Sensors. The interest to use of synthetic transport systems for sensing is somewhat obvious because our tongue and nose operate with responsive systems in lipid bilayer membranes. Over the years, the three main sensing methods have been adapted to synthetic transport systems, that is biosensing, differential sensing and the aptamer version of imunosensing.