- Chuard, N.; Gasparini, G.; Roux, A.; Sakai, N.; Matile, S. “Cell-Penetrating Poly(disulfide)s: The Dependence of Activity, Depolymerization Kinetics and Intracellular Localization on Their Length” Org. Biomol. Chem. 2015, 13, 64-67
We report that the depolymerization kinetics of cell-penetrating poly(disulfide)s depend exclusively on their length and propose a kinetic uptake model to explain why their intracellular destination changes with the increasing length from the endosomes over the cytosol to the nucleoli.