PERRON LAB

• Jordan O, Gan BH, Alwan S, Perron K, Sublet E, Ducret V, Ye H, Borchard G, Reymond JL, Patrulea V. Highly Potent Cationic Chitosan Derivatives Coupled to Antimicrobial Peptide Dendrimers to Combat Pseudomonas aeruginosa. Adv Healthc Mater. 2024. PubMed

• Segovia-Campos I, Kanellakopoulos A, Barrozo IJ, Fock-Chin-Ming E, Filella M, Fontaine AB, Pallada S, Triscone G, Perron K, Ariztegui D. Strontium-90 pollution can be bioremediated with the green microalga Tetraselmis chui. Environ Sci Process Impacts. 2024. PubMed

• Alfattani A, Queiroz EF, Marcourt L, Leoni S, Stien D, Hofstetter V, Gindro K, Perron K, Wolfender JL. One step bio-guided isolation of secondary metabolites from the endophytic fungus Penicillium crustosum using high-resolution semi-preparative HPLC. Comb Chem High Throughput Screen. 2023. PubMed

• Ducret V, Gonzalez D, Leoni S, Valentini M, Perron K. A Zur-mediated transcriptional regulation of the zinc export system in Pseudomonas aeruginosa. BMC Microbiol. 2023. PubMed

• Sandoz A, Ducret V, Gottwald GA, Vilmart G, Perron K. SINDy for delay-differential equations: application to model bacterial zinc response. Proc. R. Soc. A. 2023. Proc.R.Soc.A

• Ducret V., Gonzalez D., Perron K. Zinc homeostasis in Pseudomonas. BioMetals.  2023. PubMed

• Putra N.E., Leeflang M.A., Ducret V., Patrulea V., Fratila-Apachitei L.E., Perron K., Ye H., Zhou J., Apachitei I, Zadpoor A.A. Preventing antibiotic-resistant infections: Additively manufactured porous titanium biofunctionalized with Ag and Fe nanoparticles. Int. J. Mol. Sci.  2022. PubMed

• Ducret V., Perron K., Valentini M. Role of Two-Component System Networks in Pseudomonas aeruginosa Pathogenesis. Adv Exp Med Biol. 2022. PubMed

• Ducret V., Gonzalez D., Leoni S., Valentini M., Perron K. A Zur-mediated transcriptional regulation of the zinc export system. Preprint bioRxiv 2022: 10.1101/2022.09.30.510347. bioRxiv

• Segovia-Campos I., Filella M., Perron K. & Ariztegui D. High calcium and strontium uptake by the green microalga Tetraselmis chui is related to micropearl formation and cell growth. Environ Microbiol Rep. 2022. PubMed

• Sandoz A, Ducret V, Gottwald GA, Vilmart G, Perron K. SINDy for delay-differential equations: application to model bacterial zinc response. arXiv:2208.10826. 2022. arXiv

• Weber A, Perron K. Microworld, voyage au centre du microbiote intestinal humain. Book ISBN 9782889411078. 2022. Revue Médicale Suisse

• Huber R, Marcourt L, Quiros-Guerrero L-M, Luscher A, Schnee S, Michellod E, Ducret V, Kohler T, Perron K, Wolfender J-L, Gindro K and Ferreira Queiroz E. Chiral Separation of Stilbene Dimers Generated by Biotransformation for Absolute Configuration Determination and Antibacterial Evaluation. Front Chem. 2022. PubMed

• Patrulea V, Gan B-H, Perron K, Cai X, Abdel-Sayed P, Sublet E, Ducret V, Porroche Nerhot N, Applegate LA, Borchard G, Reymond J-L, Jordan O. Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa. Carbohydr. Polym. 2022. PubMed

• Alfattani A, Marcourt L, Hofstetter V, Ferreira Queiroz E, Leoni S, Allard P.-M, Gindro K, Stien D, Perron K, Wolfender J.-L. Combination of pseudo-LC-NMR and HRMS/MS-based molecular networking for the rapid identification of antimicrobial metabolites from Fusarium petroliphilum. Front Mol Biosci. 2021. PubMed

• Ducret V, Abdou M, Goncalves Milho C, Leoni S, Martin--Pelaud O, Sandoz A, Segovia Campos I, Tercier Waeber M, Valentini M, Perron K. Global analysis of the zinc homeostasis network in Pseudomonas aeruginosa and its gene expression dynamics. Front Microbiol. 2021. PubMed

• Pellissier L, Leoni S, Marcourt L, Ferreira Queiroz E, Lecoultre N, Quiros-Guerrero L.-M, Barthélémy M, Eparvier V, Chave J, Stien D, Gindro K, Perron K, Wolfender J.-L. Characterization of Pseudomonas aeruginosa Quorum Sensing Inhibitors from the Endophyte Lasiodiplodia venezuelensis and Evaluation of Their Antivirulence Effects by Metabolomics. Microorganisms. 2021, 9, 1807. PubMed

• Pellissier L, Koval A, Marcourt L, Ferreira Queiroz E, Lecoultre N, Leoni S, Quiros-Guerrero LM, Barthélémy M, Duivelshof BL, Guillarme D, Tardy S, Eparvier V, Perron K, Chave J, Stien D, Gindro K, Katanaev V, Wolfender JL. Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia venezuelensis. Front Chem. 2021. PubMed

• Ducret V, Abdou M, Goncalves Milho C, Leoni S, Martin--Pelaud O, Sandoz A, Segovia Campos I, Tercier Waeber M, Valentini M, Perron K. Global analysis of the zinc homeostasis network in Pseudomonas aeruginosa and its gene expression dynamics. Preprint bioRxiv 2021.05.28.446167. bioRxiv

• Righi D, Huber R, Koval A, Marcourt L, Schnee S, Le Floch A, Ducret V, Perozzo R, de Ruvo CC, Lecoultre N, Michellod E, Ebrahimi SN, Rivara-Minten E, Katanaev VL, Perron K, Wolfender JL, Gindro K, Queiroz E. Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea. J Nat Prod. 2020. PubMed

• Ducret V, Gonzalez MR, Leoni S, Valentini M, Perron K. The CzcCBA Efflux System Requires the CadA P-Type ATPase for Timely Expression Upon Zinc Excess in Pseudomonas aeruginosa. Front Microbiol. 2020. PubMed

• Hausmann S, Geiser J, Vadas O, Ducret V, Perron K, Valentini M. Auxiliary domains of the HrpB bacterial DExH-box helicase shape its RNA preferences. RNA Biol. 2020. PubMed

• Righi D, Marcourt L, Koval A, Ducret V, Pellissier L, Mainetti A, Katanaev V, Perron K, Wolfender JL, Queiroz EF. Chemo-diversification of plant extracts using a generic bromination reaction and monitoring by metabolite profiling. ACS Comb Sci. 2019. PubMed

• Ravasi D, Guidi V, Flacio E, Lüthy P, Perron K, Lüdin S, Tonolla M. Investigation of temperature conditions in Swiss urban and suburban microhabitats for the overwintering suitability of diapausing Aedes albopictus eggs. Parasites & Vectors 2018, 11:212. PubMed

• Gonzalez MR, Ducret V, Leoni S, Fleuchot B, Jafari P, Applegate LA, Raffoul W, Que Y-A, Perron K. Transcriptome Analysis of Pseudomonas aeruginosa Cultured in Human Burn Wound Exudates. Front. Cell. Infect. Microbiol.,2018. PubMed

• Gonzalez MR, Ducret V, Leoni S, Perron K. Pseudomonas aeruginosa zinc homeostasis: Key issues for an opportunistic pathogen. Biochim Biophys Acta. 2018. PubMed

• Ducret V, Gonzalez MR, Scrignari T, Perron K. OprD repression upon metal treatment requires the RNA chaperone Hfq in Pseudomonas aeruginosa. Genes. 3;7(10), 2016. PubMed

• Gonzalez MR, Fleuchot B, Lauciello L, Jafari P, Applegate LA, Raffoul W, Que Y-A, Perron K. Effect of Human Burn Wound Exudate on Pseudomonas aeruginosa Virulence. mSphere. 1(2):e00111-15, 2016. PubMed

• Abdel-Sayed P, Kaeppeli A, Siriwardena T, Darbre T, Perron K, Jafari P, Reymond JL, Pioletti DP, Applegate LA. Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages.Sci. Rep. Feb. 2016. PubMed

• Slepikas L, Chiriano G, Perozzo R, Tardy S, Kranjc-Pietrucci A, Patthey-Vuadens O, Ouertatani-Sakouhi H, Kicka S, Harrison C, Scrignari T, Perron K, Hilbi H, Soldati T, Cosson P, Tarasevicius E, Scapozza L. In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA.J. Med. Chem. Jan. 2016. PubMed

• Caine M, Zuchuat S, Weber A, Ducret V, Linder P, Perron K. BiOutils: an interface to connect university laboratories with microbiology classes in schools. FEMS Microbiol Lett. Sept. 2015. PubMed

• Caine M, Horié N, Zuchuat S, Weber A, Ducret V, Linder P, Perron K. A 3D-DNA Molecule Made of PlayMais. Science Activities. 2015 52:31-44. Science Activities

• Marguerettaz M, Dieppois G, Que Y-A, Ducret V, Zuchuat S, Perron K. Sputum containing zinc enhances carbapenem resistance, biofilm formation and virulence of Pseudomonas aeruginosa. Microb Pathog. 2014 77:36-41. PubMed

• Deakin SP, Ducret V, Bioletto S, Perron K, James RW. Modulating reconstituted high density lipoprotein functionality to target the Pseudomonas aeruginosa quorum sensing system. Life Sci. 2014 112:68–73. PubMed

• Biloa Messi B, Ho R, Meli Lannang A, Cressend D, Perron K, Nkengfack AE, Carrupt PA, Hostettmann K, Cuendet M. Isolation and biological activity of compounds from Garcinia preussii. Pharm Biol.. 2014 52:706-711. PubMed

• Dieppois G, Ducret V, Caille O, Perron K. The Transcriptional Regulator CzcR Modulates Antibiotic Resistance and Quorum Sensing in Pseudomonas aeruginosa. PLoS ONE. 2012;7(5):e38148. Epub 2012 May 29. PubMed

• Corvaglia AR, François P, Hernandez D, Perron K, Linder P, Schrenzel J. A type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical Staphylococcus aureus strains. Proc Natl Acad Sci USA. 2010 107:11954-11958. PubMed

• Caille O, Rossier C, Perron K. A copper-activated two-component system interacts with zinc and imipenem resistance in Pseudomonas aeruginosa. J Bacteriol. 2007 189:4561-4568. PubMed

• Dumas JL, van Delden C, Perron K, Köhler T. Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR. FEMS Microbiol Lett. 2006 254:217-225. PubMed

• Perron K, Comte R, van Delden C. DksA represses ribosomal gene transcription in Pseudomonas aeruginosa by interacting with RNA polymerase on ribosomal promoters. Mol Microbiol. 2005 56:1087-1102. PubMed

• Perron K, Caille O, Rossier C, Van Delden C, Dumas JL, Köhler T. CzcR-CzcS, a two-component system involved in heavy metal and carbapenem resistance in Pseudomonas aeruginosa. J Biol Chem. 2004 279:8761-8768. PubMed

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