Publications (1968 - June 2010)

B. NOTTELET, C. DI TOMMASO, K. MONDON, R. GURNY and M. MÖLLER
“Fully biodegradable polymeric micelles based on hydrophobic- and hydrophilic-functionalized poly(lactide) block copolymers”
Journal of Polymer Science: Part A: Polymer Chemistry, 48,3244-3254 (2010)

M. GAUMET, R. GURNY and F. DELIE
“Interaction of biodegradable nanoparticles with intestinal cells: The effect of surface hydrophilicity”
International Journal of Pharmaceutics, 390, 45-52 (2010)

A. CIRTOIU-HAPCA, F. BUCHEGGER, N. LANGE, L. BOSSY, R. GURNY and F. DELIE
“Benefits of anti-HER2-coated paclitaxel-loaded immune-nanoparticles in the treatment of disseminated ovarian cancer: Therapeutic efficacy and biodistribution in mice”
Journal of Controlled Release, 144, 324-331 (2010)

F. ESMAEILI, S. HEUKING, H.E. JUNGINGER and G. BORCHARD
“Progress in chitosan-based vaccine delivery systems”
Journal of Drug Delivery Science and Technology, 20(1), 53-61 (2010)

L. LUCA, M.H. CAPELLE, G. MACHAIDZE, T. ARVINTE, O. JORDAN and R. GURNY
“Physical instability, aggregation and conformational changes of recombinant human bone morphogenetic protein-2 (rhBMP-2)”
International Journal of Pharmaceutics, 391, 48-54 (2010)

C. DI TOMMASO, C. COMO, R. GURNY and M. MÖLLER
“Investigations on the lyophilisation of MPEG-hexPLA micelle based pharmaceutical formulations”
European Journal of Pharmaceutical Sciences, 40, 38-47 (2010)

O. BORGES, F. LEBRE, D. BENTO, G. BORCHARD and H.E. JUNGINGER
“Mucosal vaccines: Recent progress in understanding the natural barriers”
Pharmaceutical Research, 27(2), 211-223 (2010)

F. GUILLAUMIE, P. FURRER, O. FELT-BAEYENS, B.L. FUHLENDORFF, S. NYMAND, P. WESTH, R. GURNY and K. SCHWACH-ABDELLAOUI
“Comparative studies of various hyaluronic acids produced by microbial fermentation for potential topical ohphtalmic applications”
Journal of Biomedical Materials Research. Part A, 92(4), 1421-1430 (2010)

P.-E. LE RENARD, O. JORDAN, A. FAES, A. PETRI-FINK, H. HOFMANN, D. RÜFENACHT, F. BOSMAN, F. BUCHEGGER and E. DOELKER
“The in vivo performance of magnetic particle-loaded injectable, in situ gelling, carriers for the delivery of local hyperthermia”
Biomaterials, 31, 691-705 (2010)

C. FERRERO, D. MASSUELLE and E. DOELKER
“Towards elucidation of the drug release mechanism from compressed hydrophilic matrices made of cellulose ethers. II. Evaluation of a possible swelling-controlled drug release mechanism using dimensionless analysis”
Journal of Controlled release, 141, 223-233 (2010)

P. FURRER and R. GURNY
"Recent advances in confocal microscopy for studying drug delivery to the eye: concepts and pharmaceutical applications"
European Journal of Pharmaceutics and Biopharmaceutics, 74, 33-40 (2010)

S. LÉTOFFÉ, G. HEUCK, P. DELEPELAIRE, N.LANGE and C. WANDERSMAN
“Bacteria capture iron from heme by keeping tetrapyrrol skeleton intact”
PNAS, 106 (28), 11719-11724 (2009)

N. FOTINOS, J. MIKULIC, M. CONVERT, M.A. CAMPO, J.-C. PIFFARETTI, R. GURNY and N. LANGE
"5-ALA derivative-mediated photoinactivation of Propionibacterium acnes"
Journal of Dermatological Science, 56, 212-214 (2009)

V. MALATERRE, J. OGORKA, N. LOGGIA and R. GURNY
"Oral osmotically driven systems: 30 years of development and clinical use"
European Journal of Pharmaceutics and Biopharmaceutics (2009)

B. DEMEULE, C. PALAIS, G. MACHAIDZE, R. GURNY and T. ARVINTE
"New methods allowing the detection of protein aggregates. A case study on trastuzumab"
mAbs, 1(2), 142-150 (2009)

L. LUCA, O. JORDAN, A.-L. ROUGEMONT, B.H. WALPOTH and R. GURNY
"rhBMP-2-loaded chitosan hydrogel: Influence of formulation parameters on ectopic bone formation"
Poster, 22nd European Conference on Biomaterials, 07-11th September, 2009, Lausanne, Switzerland.

S.EPERON, L. BOSSY-NOBS, R. GURNY and Y. GUEX-CROSIER
"Biodegradable implants and cataract surgery"
Poster, 22nd European Conference on Biomaterials, 07-11th September, 2009, Lausanne, Switzerland.

D. GABRIEL, N. BUSSO, A. SO, R. GURNY, H.VAN DEN BERGH and N. LANGE
"Thrombin-sensitive photodynamic agents: A novel strategy for selective synovectomy"
Poster, 22 nd European Conference on Biomaterials, 07-11 th September, 2009, Lausanne, Switzerland.

D. MANDRACCHIA, F. INNOCENTE, B. NOTTELET, J.-C. TILLE, S. DE VALENCE, R. GURNY, B. H. WALPOTH and M. MÖLLER
"Assessment of paclitaxel in the prevention of vascular graft intima hyperplasia formation"
Proceeding 22nd European Conference on Biomaterials, 07-11th September, 2009, Lausanne, Switzerland.

B.H. WALPOTH, D. MUGNAI, J.-C. TILLE, F. INNOCENTE, B. NOTTELET, C. BERTHONNECHE, X. MONTET, S. DE VALENCE, W. MROWCZYNSKI, A. KALANGOS R. GURNY and M. MOELLER
"Biodegradable synthetic small-calibre vascular grafts: 1-year results after replacement of the rat aorta"
Proceeding 22nd European Conference on Biomaterials, 07-11th September, 2009, Lausanne, Switzerland.

M. MÖLLER, K. MONDON, C. DI TOMMASO, L. ASMUS and R. GURNY
"Injectable biodegradable poly(hexyl-substituted lactides) for drug delivery"
Proceeding 22nd European Conference on Biomaterials, 07-11th September, 2009, Lausanne, Switzerland.

N. BUTOESCU, O. JORDAN and E. DOELKER
"Intra-articular drug delivery systems for the treatment of rheumatic diseases: A review of the factors influencing their performance"
European Journal of Pharmaceutics and Biopharmaceutics, 73, 205-218 (2009)

A.CIRSTOIU-HAPCA, F. BUCHEGGER, L. BOSSY, M. KOSINSKI, R. GURNY and F. DELIE
"Nanomedicines for active targeting: Physico-chemical characterization of paclitaxel-loaded anti-HER2 immunonanoparticles and in vitro functional studies on target cells"
European Journal of Pharmaceutical Sciences, 38, 230-237 (2009)

K. MONDON, R. GURNY, M. MÖLLER
"Hexyl-substituted polylactide based micelles for cyclosporine A drug delivery"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

P. MARKLAND, G.A. WINCHESTER, R. GURNY, M. MÖLLER
"Injectable poly(hexyl-substituted lactides) for peptide delivery"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

D. JEANNERAT, C. FERRERO RODRIGUEZ, D. MASSUELLE, E. DOELKER
"Caffeine diffusion in hydroxypropylmethylcellulose gels: Effects of pH and temperature"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

N. BUTOESCU, C.A. SEEMAYER, G. PALMER, P.-A. GUERNE, C. GABAY, E. DOELKER, O. JORDAN
"Magnetically retainable intra-articular delivery system containing dexamethasone: Efficacy in an antigen-induced arthritis model in mice"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

M. VEURINK, C. STELLA, C. TABATABAY, C.J. POURNARAS, R. GURNY
"Bevacizumab and ranibizumab in association with anti-inflammatory drugs: An in-vitro stability study"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

C. EENSCHOOTEN, F. LONGIN, M. BORKOVEC, R. GURNY, K. SCHWACH-ABDELLAOUI
"Development of soft nanocarriers from novel amphiphilic hyaluronic acid derivatives towards drug delivery"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

D. MANDRACCHIA, F. INNOCENTE, B. NOTTELET, J.C. TILLE, S. DE VALENCE, R. GURNY, B.H. WALPOTH and M. MÖLLER
"Evaluation of paclitaxel-releasing synthetic biodegradable vascular grafts for the prevention of intima hyperplasia"
Proceeding 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, 2009, Copenhagen, Denmark

A. VARGAS and F. DELIE
"Potential use of biodegradable nanoparticles for the photodynamic therapy of eye diseases"
Archivos de la Sociedad Espanola de Oftalmologica, 84(4), 169-71, 173-5 (2009)

D. GABRIEL, M.-F. ZULUAGA, M.-N. MARTINEZ, M.A. CAMPO and N. LANGE
"Urokinase-plasminogen-activator sensitive polymeric photosensitizer prodrugs: design, synthesis and in vitro evaluation"
Journal of Drug Delivery Science and Technology, 19(1), 15-24 (2009)

S. MEHIER-HUMBERT, T. BETTINGER, F. YAN and R.GUY
"Influence of polymer adjuvants on the ultrasound-mediated transfection of cells in culture"
European Journal of Pharmaceutics and Biopharmaceutics, 72(3), 567-573 (2009)

M. BIVAS-BENITA, M.Y. LIN, S.M. BAL, K.E. VAN MEIJGAARDEN, K.L.M.C. FRANKEN, A.H. FRIGGEN, H.E. JUNGINGER, G. BORCHARD, M.R. KLEIN and T.H.M. OTTENHOFF
"Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice"
Vaccine, 27(30), 4010-4017 (2009)

S. HEUKING, S. ADAM-MALPEL, E. SUBLET, A. IANNITELLI, A. DI STEFANO and G. BORCHARD
"Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers"
Journal of Drug Targeting, 17(8), 662-670 (2009)

N. BUTOESCU, C. A. SEEMAYER, G. PALMER, P.-A. GUERNE, C. GABAY, E. DOELKER and O. JORDAN
"Magnetically retainable microparticles for drug delivery to the Joint: efficacy Studies in an antigen-induced artritis model in mice"
Arthritis research & therapy, 11(3), R72 (1-10)(2009)

P.-E. LE RENARD, F. BUCHEGGER, A. PETRI-FINK, F. BOSMAN, D. RUFENACHT, H. HOFMANN, E. DOELKER and O.JORDAN
"Local moderate magnetically induced hyperthermia using an implant formed in situ in a mouse tumor model"
International Journal of Hyperthermia, 25(3), 229-239 (2009)

N. BUTOESCU, O. JORDAN, P. BURDET, P. STADELMANN, A. PETRI-FINK, H. HOFMANN and E. DOELKER
"Dexamethasone-containing biodegradable superparamagnetic microparticles for intra-articular administration: Physicochemical and magnetic properties, in vitro and in vivo drug release"
European Journal of Pharmaceutics and Biopharmaceutics, 72(3), 529-538 (2009)

V. MALATERRE, J. OGORKA, N. LOGGIA and R. GURNY
"Approach to design push-pull osmotic pumps"
International Journal of Pharmaceutics, 376(1-2), 56-62 (2009)

D. GABRIEL, N. BUSSO, A. SO, H. VAN DEN BERGH, R. GURNY and N. LANGE
"Thrombin-sensitive photodynamic agents: A novel strategy for selective synovectomy in rheumatoid arthritis"
Journal of Controlled Release, 138(3), 225-234 (2009)

M. ZEISSER-LABOUEBE, M. MATTIUZZO, N. LANGE, R. GURNY and F. DELIE
"Quenching-induced deactivation of photosensitizer by nanoencapsulation to improve phototherapy of cancer"
Journal of Drug Targeting, 17(8), 619-626 (2009)

A. VARGAS, N. LANGE, A. TUDOR, C. RADOVAN, R. GURNY and F. DELIE
"Toward the understanding of the photodynamic activity of m-THPP encapsulated in PLGA nanoparticles: correlation between nanoparticle properties and in vivo activity"
Journal of Drug Targeting, 17(8), 599-609 (2009)

F. INNOCENTE, D. MANDRACCHIA, E. PEKTOK, B. NOTTELET, J.-C. TILLE, S. DE VALENCE, G. FAGGIAN, A. MAZZUCCO, A. KALANGOS, R. GURNY, M. MOELLER and B. B. WALPOTH
"Paclitaxel-eluting biodegradable synthetic vascular prosthese. A step towards reduction of neointima formation?"
Circulation, 120 (11 suppl1), S37-S45 (2009)

M. TROCCAZ, G. BORCHARD, C. VUILLEUMIER, S. RAVIOT-DERRIEN, Y. VAN NICLASS, S. BECCUCCI and C. STARKENMANN
"Gender-specific differences between the concentrations of nonvolatile (R)/(S)-3-methyl-3-sulfanylhexan-1-ol and (R)/(S)-3-hydroxy-3-methyl-hexanoic acid odor precursors in axillary secretions"
Chemical Senses, 34(3), 203-210 (2009)

M. ZEISSER-LABOUEBE, F. DELIE, R. GURNY and N. LANGE
"Screening of nanoparticulate delivery systems for the photodetection of cancer in a simple and cost-effective model"
Nanomedicine (London, England), 4(2), 135-43 (2009)

V. MALATERRE, M. PEDERSEN, J. OGORKA, R. GURNY, N. LOGGIA and P.F. TADAY
"Terahertz pulsed imaging, a novel process analytical tool to investigate the coating characteristics of push-pull osmotic systems"
European Journal of Pharmaceutics and Biopharmaceutics (2009)

N. BUTOESCU, C.A. SEEMAYER, M. FOTI, O. JORDAN and E. DOELKER
"Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis"
Biomaterials, 30, 1772-1780 (2009)

M.A.H. CAPELLE, R. GURNY and T. ARVINTE
"A high throughput protein formulation platform: Case study of salmon calcitonin"
Pharmaceutical Research, 26 (1), 118-128 (2009)

V. MALATERRE, H. METZ, J. OGORKA, R. GURNY, N. LOGGIA and K. MÄDER
"Benchtop-magnetic resonance imaging (BT-MRI) characterization of push-pull osmotic controlled release systems"
Journal of Controlled Release, 133, 31-36 (2009)

M. GAUMET, R. GURNY and F. DELIE
"Localization and quantification of biodegradable particles in an intestinal cell model: the influence of particle"
European Journal of Pharmaceutical Sciences, 36, 465-473 (2009)

E. FURRER, M. BERDUGO, C. STELLA, F. BEHAR-COHEN, R. GURNY, U. FEIGE, P.D. LICHTLEN and D.M. URECH
"Pharmacokinetics and posterior segment biodistribution of ESBA105, an anti-TNF- a single-chain antibody, upon topical administration to the rabbit eye"
Investigative Ophthalmology & Visual Science, 50 (2), 771-778 (2009)

V. MALATERRE, J. OGORKA, N. LOGGIA and R. GURNY
"Evaluation of the tablet core factors influencing the release kinetics and the loadability of push-pull osmotic systems"
Drug Development and Industrial Pharmacy , 35 (4), 433-439 (2009)

M. ZEISSER-LABOUEBE, F. DELIE, R. GURNY and N. LANGE
"Benefits of nanoencapsulation fort the hypercin-mediated photodetection of ovarian micrometastases"
European Journal of Pharmaceutics and Biopharmaceutics, 71, 207-213 (2009)

E. PATOIS, S.OSORIO-DA CRUZ, J.-C. TILLE, B. WALPOTH, R. GURNY and O. JORDAN
"Novel thermosensitive chitosan hydrogels: In vivo evaluation"
Journal of Biomedical Material Research Part A

B. NOTTELET, E. PEKTOK, D. MANDRACCHIA, J.-C. TILLE, B. WALPOTH, R. GURNY and M. MOELLER
"Factorial design optimization and in vivo feasibility of poly( e -caprolactone)-micro-and nanofiber-based small diameter vascular grafts"
Journal of Biomedical Materials Research Part A

K. MONDON, R. GURNY and M. MOELLER
"Colloidal drug delivery systems. Recent advances with polymeric micelles"
Chimia, 62 (10), 832-840 (2008)

A.M.M. SADEGHI, F.A. DORKOOSH, M.R. AVADI, M. WEINHOLD, A. BAYAT, F. DELIE, R. GURNY, B. LARIJANI, M. RAFIEE-TEHRANI and H.E. JUNGINGER
"Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells"
European Journal of Pharmaceutics and Biopharmaceutics, 70, 270-278 (2008)

M. DIAS, A.NAIK, R. H.GUY, J. HADGRAFT and M. E. LANE
"In vivo infrared spectroscopy studies of alkanol effects on human skin"
European Journal of Pharmaceutics and Biopharmaceutics, 69(3), 1171-1175 (2008)

O. BORGES, A. CORDEIRO-DA-SILVA, J.TAVARES, N.SANTAREM, A. DE SOUSA, G .BORCHARD and H. E .JUNGINGER
"Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles"
European Journal of Pharmaceutics and Biopharmaceutics, 69(2), 405-416 (2008)

S. BOUILLAGUET, B. OWEN, J. C. WATAHA, M. A. CAMPO, N. LANGE and J. SCHRENZEL
"Intracellular reactive oxygen species in monocytes generated by photosensitive chromophores activated with blue light"
Dental Materials, 24(8), 1070-1076 (2008)

M.-F. ZULUAGA and N. LANGE
"Combination of photodynamic therapy with anti-cancer agents"
Current Medicinal Chemistry, 15(17), 1655-1673 (2008)

N. BUTOESCU, O. JORDAN, A. PETRI-FINK, H. HOFMANN and E. DOELKER
"Co-encapsulation of dexamethasone 21-acetate and SPIONs into biodegradable polymeric microparticles designed for intra-articular delivery"
Journal of Microencapsulation, 25(5), 339-350 (2008)

M.H. CAPELLE and T. ARVINTE
“High-throughput formulation screening of therapeutic proteins”
Drug Discovery Today: Technologies, 5 (2-3), e71-e78 (2008)

C. FERRERO, D. MASSUELLE, D. JEANNERAT and E. DOELKER
"Towards elucidation of the drug release mechanism from compressed hydrophilic matrixes made of cellulose ethers. I. Pulse-field-gradient spin-echo NMR study of sodium salicylate diffusivity in swollen hydrogels with respect to polymer matrix physical structure"
Journal of Controlled Release, 128(1), 71-79 (2008)

M. BERDUGO POLAK, F. VALAMANESH, O. FELT, A. TORRIGLIA, J.-C. JEANNY, J.-L. BOURGES, P. RAT, A. THOMAS-DOYLE, D. BENEZRA, R. GURNY and F. BEHAR-COHEN
"Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma "
Investigative ophthalmology & visual science, 49(7), 2993-3003 (2008)

S. COLLAUD, Q. PENG, R. GURNY and N. LANGE
"Thermosetting gel for the delivery of 5-aminolevulinic acid esters to the cervix"
Journal of Pharmaceutical Sciences, 97(7), 2680-2690 (2008)

P. FURRER, O. FELT and R. GURNY
"Bioadhesive Ophthalmic Drug Inserts (BODI) for veterinary use"
in: Drugs and the pharmaceutical sciences, volume 184, second edition, volume 2edited by M.J. Rathbone and al.
Modified-release drug delivery technology, part II: Ocular Technologies, 7, 101-107 (2008)

L. BOSSY, S. ERICKSON, R. GURNY and F. DELIE
"Intraocular implants for controlled drug delivery"
in: Drugs and the pharmaceutical sciences, volume 184, second edition, volume 2edited by M.J. Rathbone and al.
Modified-release drug delivery technology, part II: Ocular Technologies, 6, 85-99 (2008)

P. FURRER, F. DELIE and B. PLAZONNET
"Ophthalmic drug delivery"
in: Drugs and the pharmaceutical sciences, volume 184, second edition, volume 2,edited by M.J. Rathbone and al.
Modified-release drug delivery technology, part II: Ocular Technologies, 5, 59-84 (2008)

S. SIEPE, B. LUECKEL, A. KRAMER, A. RIES and R. GURNY
"Assessment of tailor-made HPMC-based matrix minitablets comprising a weakly basic drug compound"
Drug Development and Industrial Pharmacy, 34, 46-52 (2008)

S. EPERON, L. BOSSY-NOBS, I.K. PETROPOULOS, R. GURNY and Y. GUEX-CROSIER
"A biodegradable drug delivery system for the treatment of postoperative inflammation"
International Journal of Pharmaceutics, 352, 240-247 (2008)

N. FOTINOS, M. CONVERT, J.-C. PIFFARETTI, R. GURNY and N. LANGE
"Effects on gramm-negative and gram-positive bacteria mediated by 5-aminolevulinic acid and 5-aminolevulinic acid derivatives"
Antimicrobial agents and Chemotherapy, 52 (4), 1366-1373 (2008)

M. GAUMET, A. VARGAS, R. GURNY and F. DELIE
"Nanoparticles for drug delivery: The need for precision in reporting particle size parameters"
European Journal of Pharmaceutics and Biopharmaceutics, 69, 1-9 (2008)

M. JU, C. MAILHOS, J. BRADLEY, T. DOWIE, M. GANLEY, G. COOK, P. CALIAS, N. LANGE, A.P. ADAMIS, D.T. SHIMA and G. S. ROBINSON
"Simultaneous but not prior inhibition of VEGF165 enhances the efficacy of photodynamic therapy in multiple models of ocular neovascularisation"
Investigative Ophthalmology & Visual Science, 49 (2), 662-670 (2008)

A. VARGAS, M. EID, M. FANCHAOUY, R. GURNY and F. DELIE
In vivo photodynamic activity of photosensitizer-loaded nanoparticles: Formulation properties, administration parameters and biological issues involved in PDT outcome”
European Journal of Pharmaceutics and Biopharmaceutics, 69, 43-53 (2008)

M.A.H. CAPELLE, R. GURNY and T. ARVINTE
“High throughput methods to characterize protein permeation and release”
International Journal of Pharmaceutics, 350, 272-278 (2008)

C. HERKENNE, I. ALBERTI, A. NAIK, Y.N. KALIA, F.-X. MATHY, V. PREAT and R.H. GUY
"In vivo methods for the assessment of topical drug bioavailability"
Pharmaceutical Research, 25 (1), 87-103 (2008)

C. HERKENNE, A. NAIK, Y.N. KALIA, J. HADGRAF and R.H. GUY
"Effect of propylene glycol on ibuprofen absorption into human skin in vivo "
Journal of Pharmaceutical Sciences, 97 (1), 185-197 (2008)

Y.B. SCHUETZ, R. GURNY and O. JORDAN
"A novel thermoresponsive hydrogel based on chitosan"
European Journal of Pharmaceutics and Biopharmaceutics, 68, 19-25 (2008)

S. COLLAUD, T. WARLOE, O. JORDAN, R. GURNY and N. LANGE
"Clinical evaluation of bioadhesive hydrogels for topical delivery of hexylaminolevulinate to Barrett's esophagus"
Journal of Controlled Release, 123, 203-210 (2007)

A. VARGAS, M. ZEISSER-LABOUEBE, N. LANGE, R. GURNY and F. DELIE
"The chick embryo and its chorioallantoic membrane (CAM) for the in vivo evaluation of drug delivery systems"
Advanced Drug Delivery Reviews, 59, 1162-1176 (2007)

I. DIAZ del CONSUELO, F. FALSON, R.H. GUY and Y. JACQUES
"Ex-vivo evaluation of bioadhesive films for buccal delivery of fentanyl"
Journal of Controlled Release, 122, 135-140 (2007)

B. MUDRY, P.-A. CARRUPT, R.H. GUY and M.B. DELGADO-CHARRO
"Quantitative structure-permeation relationship for iodontophoretic transport across the skin"
Journal of Controlled Release, 122, 165-172 (2007)

S. MEHIER-HUMBERT, F. YAN, P. FRINKING, M. SCHNEIDER, R. H. GUY and T. BETTINGER
"Ultrasound-mediated gene delivery: Influence of contrast agent on transfection"
Bioconjugate Chem., 18, 652-662 (2007)

M. GAUMET, R. GURNY and F. DELIE
"Fluorescent biodegradable PLGA particles with narrow size distributions: Preparation by means of selective centrifugation"
International Journal of Pharmaceutics, 342, 222-230 (2007)

F. LALLEMAND, E. VARESIO, O. FELT-BAEYENS, L. BOSSY, G. HOPFGARTNER and R. GURNY
"Biological conversion of a water-soluble prodrug of cyclosporine A"
European Journal of Pharmaceutics and Biopharmaceutics, 67, 555-561 (2007)

M.A. CAMPO, D. GABRIEL, P. KUCERA, R. GURNY and N. LANGE
"Polymeric photosensitizer prodrugs for photodynamic therapy"
Photochemistry and Photobiology, 83, 958-965 (2007)

D. GABRIEL, M.A. CAMPO, R. GURNY and N. LANGE
"Tailoring protease-sensitive photodynamic agents to specific disease-associated enzymes"
Bioconjugate Chem., 18, 1070-1077 (2007)

O. BORGES, G. BORCHARD, A. DE SOUSA, H.E. JUNGINGER, A. CORDEIRO-DA-SILVA
"Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers"
International Journal of Pharmaceutics, 337, 254-264 (2007)

L. VAUCHER, P.JICHLINSKI, N. LANGE, C. RITTER-SCHENK, H.VAN DEN BERGH and P. KUCERA
"Hexyl-aminolevulinate-mediated photodynamic therapy: How to spare normal urothelium. An in vitro approach"
Lasers in Surgery and Medicine, 39, 67-75 (2007)

Y. FRADET, H.B. GROSSMAN, L. GOMELLA, S. LERNER, M. COOKSON, D. ALBALA, M.J. DROLLER (PC B302/01 Study Group, N. Lange and al.
"A comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of carcinoma in situ in patients with bladder cancer: A phase III, multicenter study"
The Journal of Urology, 178, 68-73 (2007)

H.B. GROSSMAN, L. GOMELLA, Y. FRADET, A. MORALES, J. PRESTI, C. RITENOUR, U. NSEYOS, M.J. DROLLER (PC B302/01 Study Group, N. Lange and al.
"A phase III, multicenter comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of superficial papillary lesions in patients with bladder cancer"
The Journal of Urology, 178, 62-67 (2207)

A. LAURENT, F. MOTTU, R. CHAPOT, J.Q. ZHANG, O. JORDAN, D.A. RÜFENACHT, E. DOELKER and J.-J. MERLAND
"Cardiovascular effects of selected water-miscible solvents for pharmaceutical injections and embolization materials: A comparive hemodynamic study using a sheep model"
PDA Journal of Pharmaceutical Science and Technology, 61 (2), 64-74 (2007)

M.-F ZULUAGA, C. MAIHOS, G. ROBINSON, D.T. SHIMA, R. GURNY and N. LANGE
"Synergies of VEGF inhibition and photodynamic therapy in the treatment of age-related macular degeneration"
Investigative Ophthalmology & Visual Science, 48 (4), 1767-1772 (2007)

T. TRIMAILLE, R. GURNY and M. MÖLLER
"Poly(hexyl-substituted lactides): Novel injectable hydrophobic drug delivery systems"
Journal of Biomedical Materials Research Part A., 80(1), 55-65 (2007)

M.-L. LEICHTNAM, H. ROLLAND, P. WÜTHRICH and R.H. GUY
"Impact of antinucleants on transdermal delivery of testosterone from a spray"
Journal of Pharmaceutical Sciences, 96 (1), 84-92 (2007)

B. DEMEULE, M.J. LAWRENCE, A.F. DRAKE, R. GURNY and T. ARVINTE
"Characterization of protein aggregation: The case of a therapeutic immunoglobulin"
Biochimica and Biophysica Acta, 1774, 146-153 (2007)

A. CIRSTOIU-HAPCA, L. BOSSY-NOBS, F. BUCHEGGER, R. GURNY and F. DELIE
"Differential tumor cell targeting of anti-HER2 (Herceptin(R) ) and anti-CD20 (Mabthera(R) ) coupled nanoparticles"
International Journal of Pharmaceutics, 331(2), 190-196 (2007)

B. DEMEULE, R. GURNY and T. ARVINTE
"Detection and characterization of protein aggregates by fluorescence microscopy"
International Journal of Pharmaceutics, 329, 37-45 (2007)

M.A.H. CAPELLE, R. GURNY and T. ARVINTE
"High throughput screening of protein formulation stability: Practical considerations"
European Journal of Pharmaceutics and Biopharmaceutics, 65, 131-148 (2007)

C. HERKENNE, A. NAIK, Y.N. KALIA, J. HADGRAFT and R.H. GUY
"Ibuprofen transport into and through skin from topical formulations: in vitro-in vivo comparison"
Journal of Investigative Dermatology, 127, 135-142 (2007)

N. ABLA, A. NAIK, R.H. GUY and Y.N. KALIA
"Topical iontophoresis of Valaciclovir hydrochloride improves cutaneous Aciclovir delivery"
Pharmaceutical Research, 23 (8), 1842-1849 (2006)

C. HERKENNE, A. NAIK, Y.N. KALIA, J. HADGRAFT and R.H. GUY
"Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man"
Pharmaceutical Research, 23 (8), 1850-1856 (2006)

O. BORGES, A. CORDEIRO-DA-SILVA, S.G. ROMEIJN, M. AMIDI, A. DE SOUSA, G. BORCHARD and H.E. JUNGINGER
"Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination"
Journal of Controlled Release, 114, 348-358 (2006)

M.-L. LEICHTNAM, H. ROLLAND, P. WÜTHRICH and R.H. GUY
"Formulation and evaluation of a testosterone transdermal spray"
Journal of Pharmaceutical Sciences, 95 (8), 1693-1702 (2006)

M.-L. LEICHTNAM, H. ROLLAND, P. WÜTHRICH and R.H. GUY
"Enhancement of transdermal testosterone delivery by supersaturation"
Journal of Pharmaceutical sciences, 95 (11), 2373-2379 (2006)

S. SIEPE, B. LUECKEL, A. KRAMER, A. RIES and R. GURNY
"Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH"
International Journal of Pharmaceutics, 316, 14-20 (2006)

Y.B. SCHUETZ, P.-A. CARRUPT, A. NAIK, R.H. GUY and Y.N. KALIA
"Structure-permeation relationship for the non-invasive transdermal delivery of cationic peptides by iontophoresis"
European Journal of Pharmaceutical Sciences, 29, 53-59 (2006)

J.B. BOURGES, C. BLOQUEL, A. THOMAS, F. FROUSSART, A. BOCHOT, F. AZAN, R. GURNY, D. BENEZRA and F. BEHAR-COHEN
"Intraocular implants for extended drug delivery: Therapeutic applications"
Advanced Drug Delivery Reviews, 58, 1182-1202 (2006)

J.L. BOURGES, F. LALLEMAND, E. AGLA, K. BESSEGHIR, J.M. DUMONT, D. BENEZRA, R. GURNY and F. BEHAR-COHEN
"Evaluation of a topical clyclosporine A prodrug on corneal graft rejection in rats"
Molecular Vision, 12, 1461-1466 (2006)

M. ZEISSER-LABOUEBE, N. LANGE, R. GURNY and F. DELIE
"Hypericin-loaded nanoparticles for the photodynamic treatment of ovarian cancer"
International Journal of Pharmaceutics, 326, 174-181 (2006)

O. DUDECK, O. JORDAN, K.T. HOFFMANN, A.F. OKUDUCU, I HUSMANN, T. KREUZER- NAGY, K. TESMER, P. PODRABSKY, H. BRUHN, J. HILBORN, D.A. RÜFENACHT, E. DOELKER and R. FELIX
"Embolization of experimental wide-necked aneurysms with iodine-containing polyvinyl alcohol solubilized in a low-angiotoxicity solvent"
American Journal of Neuroradiology, 27, 1849-1855 (2006)

O. DUDECK, O. JORDAN, K.T. HOFFMANN, A.F. OKUDUCU, K. TESMER, T. KREUZER- NAGY, D.A. RÜFENACHT, E. DOELKER and R. FELIX
"Organic solvents as vehicles for precipitating liquid embolics: A comparative angiotoxicity study with superselective injections of swinw rete mirabile"
American Journal of Neuroradiology, 27, 1900-1906 (2006)

C.A. NGUYEN, Y. KONAN-KOUAKOU, E. ALLEMANN, E. DOELKER, D. QUINTANAR- GUERRERO, H. FESSI and R. GURNY
"Preparation of surfactant-free nanoparticles of methacrylic acid copolymers used for film coating"
AAPS PharmSciTech, 7(3), article 63 (2006)

O. DUDECK, A.F. OKUDUCU, O. JORDAN, K. TESMER, M. PECH, E. WEIGANG, D.A. RÜFENACHT, E. DOELKER and R. FELIX
"Volume changes of experimental carotid sidewall aneurysms due to embolization with liquid embolic agents: A multidetector CT angiography study".
CardiVascular and Interventional Radiology, 29, 1053-1059 (2006)

M. ZEISSER-LABOUEBE, A. VARGAS and F. DELIE
"Nanoparticles for photodynamic therapy of cancer"
in: Nanotechnologies for the Life Sciences, vol 6, Nanomaterials for Cancer Therapy, edited by Challa S.S.R.Kumar, 2, 40-86 (2006)

N. FOTINOS, M.A. CAMPO, F. POPOWYCZ, R. GURNY and N. LANGE
"5-Aminolevulinic acid derivatives in photomedicine: Characteristics, application and persperctives"
Photochemistry and Photobiology, 82, 994-1015 (2006)

O. FELT-BAEYENS, S. EPERON, P. MORA, D. LIMAL, S. SAGODIRA, P. BRETON, B. SIMONAZZI, L. BOSSY-NOBS, Y. GUEX-CROSIER and R. GURNY
"Biodegradable scleral implants as new triamcinolone acetonide delivery systems"
International Journal of Pharmaceutics, 322, 6-12 (2006)

M-L. LEICHTNAM, H. ROLLAND, P. WÜTHRICH and R.H. GUY
"Testosterone hormone replacement therapy: State-of-the-Art and emerging technologies"
Pharmaceutical Research, 23 (6), 1117-1132 (2006)

M.-L. LEICHTNAM, H. ROLLAND, P. WÜTHRICH and R.H. GUY
"Identification of penetration enhancers for testosterone transdermal delivery from spray formulations"
Journal of Controlled Release, 113, 57-62 (2006)

L. COSTANTINO, F. GANDOLFI, L. BOSSY-NOBS, G. TOSI, R. GURNY, F. RIVASI, M.A. VANDELLI and F. FORVI
"Nanoparticulate drug carriers based on hybrid poly( D,L -lactide- co -glycolide)-dendron structures"
Biomaterials, 27, 4635-4645 (2006)

T. TRIMAILLE, K. MONDON, R. GURNY and M. MÖLLER
"Novel polymeric micelles for hydrophobic drug delivery based on biodegradable poly(hexyl- substituted lactides)"
International Journal of Pharmaceutics, 319, 147-154 (2006)

S. COLLAUD, P. JICHLINSKI, A. MARTI, D. AYMON, R. GURNY and N. LANGE
"An open pharmacokinetic study of hexylaminolevulinate-induced photodiagnosis after intravesical administration"
Drugs in R&D , 7 (3), 173-186 (2006)

O. DUDECK, O. JORDAN, K.-T. HOFFMANN, K. TESMER, T. KREUZER-NAGY, P. PODRABSKY, M. HEISE, R. MEYER, A.F. OKUDUCU, H. BRUHN, J. HILBORN, D.A. RUFENACHT, E. DOELKER and R. FELIX
"Intrisinsically radiopaque iodine-containing polyvinyl alcohol as a liquid embolic agent: evaluation in experimental wide-necked aneurysms."
Journal of neurosurgery, 104 (2), 290-297 (2006)

M.A. CAMPO and N. LANGE
"Fluorescence diagnosis using enzyme-related metabolic abnormalities of neoplasia"
Journal of Environmental Pathology, Toxicology and Oncology, 25 (1-2), 341-372 (2006)

B. MUDRY, R.H. GUY and M.B. DELGADO-CHARRO
"Electromigration of ions across the skin: Determination and prediction of transport numbers"
Journal of Pharmaceutical Sciences, 95(3), 561-569 (2006)

B. MUDRY, R.H. GUY and M.B. DELGADO-CHARRO
"Prediction of iontophoretic transport across the skin"
Journal of Controlled Release, 111, 362-367 (2006)

B. MUDRY, R.H. GUY and M.B. DELGADO-CHARRO
"Transport numbers in transdermal iontophoresis"
Biophysical Journal, 90, 2822-2830 (2006)

S. SIEPE, W. HERRMANN, H.-H. BORCHERT, B. LUECKEL, A. KRAMER, A. RIES and R. GURNY
"Microenvironmental pH and microviscosity inside pH-controlled matrix tablets: An EPR imaging study"
Journal of Controlled Relase, 112, 72-78 (2006)

L. NOBS, F. BUCHEGGER, R. GURNY and E. ALLEMANN
"Biodegradable nanoparticles for direct or two-step tumor immunotargeting"
Bioconjugate Chemistry, 17(1), 139-145 (2006)

M.A.H. CAPELLE, R. GURNY and T. ARVINTE
"High throughput screening of protein-protein interactions"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

M. ZEISSER-LABOUEBE, N. LANGE, R. GURNY and F. DELIE
"Hypericin-loaded nanoparticles for photodynamic therapy of ovarian cancer"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

A. VARGAS, T. ARVINTE, R. GURNY and F. DELIE
"Vascular occlusion induced by photosensitizer-loaded nanoparticles: Pharmaceutical and photophysical parameters"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

A.G. SARRAF, S. CHERKAOUI , R. GURNY and E. DOELKER
"Controlled release extrudates tailored by processing parameters: A chemometric design study"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

M. POURTIER, R. GURNY and F. DELIE
"In vitro screening of biodegradable polymeric particles for oral administration of drugs"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

N. BUSSO, G.KIRDAITE, M.A. CAMPO, P.KUCERA, R. GURNY, A. SO and N. LANGE
"Enzyme activated photodynamic therapy of rheumatoid arthritis"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

N. ABLA, A. NAIK, R.H. GUY and Y.N. KALIA
"Improving cutaneous bioavailability and efficacy of antiherpetic drugs"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

M. MÖLLER, T. TRIMAILLE, K. MONDON and R. GURNY
"Poly(hexyl-substituted-lactides): Novel functionalized PLA for delivery of hydrophobic drugs from semi-solid homo polymers and PEG-copolymer-micelles"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

A. HAPCA, L. BOSSY-NOBS, F. BUCHEGGER, R. GURNY and F. DELIE
"Evaluation of Herceptin ® and Mabthera ® labeled nanoparticles for specific tumor targeting"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

N. FOTINOS, M. CONVERT, J.C. PIFFARETTI and N. LANGE
"Optimisation of 5-ALA-mediated bacterial photo-inactivation by derivatization to target gram negative bacteria"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

S. COLLAUD, E. CINESI, Q.PENG, R. GURNY and N. LANGE
"Evaluation of a topical formulation of 5-aminolevulinic acid esters for the photodynamic treatment of cervical neoplasia"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

M.A. CAMPO, D. GABRIEL R. GURNY and N. LANGE
"New targeting strategies in photodynamic therapy: Proteolytically induced photosensitization"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

N. BUTOESCU, O. JORDAN, A. FINK, H. HOFMANN, P.-A. GUERNE, G. GABAY and E. DOELKER
"Magnetic PLGA microspheres as intra-articular drug delivery system"
Proc. 5 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva , 27-30 March (2006)

M.J. BLANCO-PRIETO and F. DELIE
"Particulate systems for oral drug delivery"
in: Drugs and the pharmaceutical sciences, edited by Simon Benita, 2nd edition. Microencapsulation: methods and Industrial Applications, 521-561 (2006)

J.-C. LEROUX, A. VARGAS, E. DOELKER, R. GURNY and F. DELIE
"The use of drug-loaded nanoparticles in cancer chemotherapy"
in: Drugs and the pharmaceutical sciences, edited by Simon Benita, 2nd edition. Microencapsulation: methods and Industrial Applications, 625-671 (2006)

L. BOSSY-NOBS, R. GURNY and E. ALLEMANN
"Coupling methods to obtain ligand-targeted liposomes and nanoparticles"
in: Drugs and the pharmaceutical sciences, edited by Simon Benita, 2nd edition. Microencapsulation: methods and Industrial Applications 123-147 (2006)

B. DEMEULE, R. GURNY and T. ARVINTE
"Where disease pathogenesis meets protein formulation: Renal deposition of immunoglobulin aggregates"
European Journal of Pharmaceutics and Biopharmaceutics, 62, 121-130 (2006)

S. MONNOYER, S. CAPANCIONI, M. RICHARD, M. PACAUD and J. GUYONNET
"Development of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of flurogestone acetate in ovine plasma"
Journal of Chromatography B, 819, 245-251 (2005)

L. VAUCHER, P. JICHLINSKI, N. LANGE, C. RITTER-SCHENK, H. van den BERGH and P. KUCERA
"Sparing of normal urothelium in hexyl-aminolevulinate mediated photodynamic therapy"
Proc. of SPIE, Bellingham, WA, vol. 5686, 193-198 (2005)

A. SARRE, N. LANGE, P. KUCERA and E. RADDATZ
"mitoK ATP channel activation in the postanoxic developing heart protects E-coupling via NO-, ROS-, and PKC- dependent pathways"
American Journal of Physiology -Heart and Circulatory Physiology, 288, H1611-H1619 (2005)

A. SIEG, R.H. GUY, M.B. DELGADO-CHARRO
"Noninvasive and minimally invasive methods for transdermal glucose monitoring"
Diabetes Technology & Therapeutics, 7 (1), 174-197 (2005)

I. DIAZ DEL CONSUELO, F. FALSON, R.H. GUY and Y. JACQUES
"Transport of Fentanyl through pig buccal and esophageal epithelia in vitro . Influence of concentration and vehicle pH."
Pharmaceutical Research, 22 (9), 1525-1529 (2005)

I. DIAZ DEL CONSUELO, Y. JACQUES, G.-P. PIZZOLATO, R.H. GUY and F. FALSON
"Comparison of the lipid composition of porcine buccal and esophageal permeability barriers"
Archives of Oral Biology, 50, 981-987 (2005)

N. ABLA, A. NAIK, R.H. GUY and Y.N. KALIA
"Contributions of electromigration and electroosmosis to peptide iontophoresis across intact and impaired skin"
Journal of Controlled Release, 108, 319-330 (2005)

N. ABLA, L. GEISER, M. MIRGALDI, A. NAIK, J.-L. VEUTHEY, R.H. GUY and Y.N. KALIA
"Capillary zone electrophoresis for the estimation of transdermal iontophoretic mobility"
Journal of Pharmaceutical Sciences, 94 (12), 2667-2675 (2005)

I. DIAZ DEL CONSUELO, G.-P. PIZZOLATO, F. FALSON, R.H. GUY and Y. JACQUES
"Evaluation of pig esophageal mucosa as a permeability barrier model for buccal tissue"
Journal of Pharmaceutical Sciences, 94 (12), 2777-2788 (2005)

A. NADA, A. NAIK, R.H. GUY and Y.N. KALIA
"Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis"
Pharmaceutical Research, 22 (12), 2069-2078 (2005)

U. BILATI, E. ALLEMANN and E. DOELKER
"Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues"
AAPS PharmSciTech, 6(4), E594-E604 (2005)

S. GALINDO-RODRIGUEZ, E. ALLEMANN, H. FESSI and E. DOELKER
"Polymeric nanoparticles for oral delivery of drugs and vaccines: A critical evaluation of in vivo studies"
Critical Reviews in Therapeutic Drug Carrier Systems, 22 (5), 419-463 (2005)

S. GALINDO-RODRIGUEZ, E. ALLEMANN, E. DOELKER and H. FESSI
"Versatility of three techniques for preparing ibuprofen-loaded methacrylic acid copolymer nanoparticles of controlled sizes"
Journal Drug Delivery Sciences and Technoligy, 15(5), 347-354 (2005)

Y.B. SCHUETZ, A. NAIK, R.H. GUY, E. VUARIDEL and Y.N. KALIA
"Transdermal iontophoretic delivery of triptorelin in vitro"
Journal of Pharmaceutical Sceinces, 94 (10), 2175-2182 (2005)

Y.B. SCHUETZ, A. NAIK, R.H. GUY and Y.N. KALIA
"Effect of amino acid sequence on transdermal iontophoretic peptide delivery"
European Journal of Pharmaceutical Sciences, 26, 429-437 (2005)

O. JORDAN, E. DOELKER and D.A. RÜFENACHT
"Biomaterials used in injectable implants (liquid embolics) for percutaneous filling of vascular spaces"
CardioVascular and Interventional Radiology, 28, 561-569 (2005)

U. BILATI, E. ALLEMANN and E. DOELKER
"Protein drugs entrapped within micro- and nanoparticles: An overview of therapeutic challenges and scientific issues"
Drug Delivery Technology, 5 (8),41-47 (2005)

D. QUINTANAR-GUERRERO, D. TAMAYO-ESQUIVEL, A. GANEM-QUINTANAR, E. ALLEMANN and E. DOELKER
"Adaptation and optimization of the emulsification-diffusion technique to prepare lipidic nanospheres"
European Journal of Pharmaceutical Sciences, 26, 211-218 (2005)

Y.B. SCHUETZ, A. NAIK, R.H. GUY, E. VUARIDEL and Y.N. KALIA
"Transdermal iontophoretic delivery of vapreotide acetate across porcine skin"
in vitro" Pharmaceutical Research, 22 (8), 1305-1312 (2005)

J. CAZARES-DELGADILLO, A. NAIK, Y.N. KALIA, D. QUINTANAR-GUERRERO and A. GANEM-QUINTANAR
"Skin permeation enhancement by sucrose esters: A pH-dependent phenomenon"
International Journal of Pharmaceutics, 297, 204-212 (2005)

F. LALLEMAND, P. PEROTTET, O. FELT-BAEYENS, W. KLOETI, F. PHILIPPOZ, J. MARFURT, K. BESSEGHIR and R. GURNY
"A water-soluble prodrug of cyclosporine A for ocular application: A stability study"
European Journal of Pharmaceutical Sciences, 26, 124-129 (2005)

Y.B. SCHUETZ, A. NAIK, R.H. GUY and Y.N. KALIA
"Emerging strategies for the transdermal delivery of peptide and protein drugs"
Expert Opinion Drug Delivery, 2(3), 533-548 (2005)

S. A. GALINDO-RODRIGUEZ, F. PUEL, S. BRIANCON, E. ALLEMANN, E. DOELKER and H. FESSI
"Comparative scale-up of three methods for producing ibuprofen-loaded nanoparticles"
European Journal of Pharmaceutical Sciences, 25, 357-367 (2005)

O. JORDAN, D.A. RUFENACHT, C. ISELIN and E. DOELKER
"Biomaterials for injectable therapeutic implants"
Chimia, 59 (6), 353-356 (2005)

T. TRIMAILLE, R. GURNY and M. MÖLLER
"Synthesis and properties of novel poly(hexyl-substituted lactides) for pharmaceutical applications"
Chimia, 59 (6), 348-352 (2005)

R.A. BEJJANI, F. BEHAR-COHEN, D. BENEZRA, R. GURNY and F. DELIE
"Polymeric nanoparticles for drug delivery to the posterior segment of the eye "
Chimia, 59 (6), 344-347 (2005)

P. FURRER, F. LALLEMAND, G.M. PALADINO, M.G. MAZZONE and R. GURNY
"Study by confocal laser scanning microscopy of the influence of hydrogels on the wound healing rate after mechanical corneal injury"
Chimia, 59 (6), 340-343 (2005)

E. DOELKER, U. BILATI, C.A. NGUYEN, S. GALINDO-RODRIGUEZ and A.G.SARRAF
"Processing of polymeric dosage forms for advanced drug delivery: From melt-extrudates to nanoparticles"
Chimia, 59 (6), 336-339 (2005)

S. MEHIER-HUMBERT, T. BETTINGER, F. YAN and R.H. GUY
"Ultrasound-mediated gene delivery: Kinetics of plasmid internalization and gene expression"
Journal of Controlled Release, 104, 203-211 (2005)

S. MEHIER-HUMBERT, T. BETTINGER, F. YAN and R.H. GUY
"Plasma membrane poration induced by ultrasound exposure: Implication for drug delivery"
Journal of Controlled Release, 104, 213-222 (2005)

P. MORA, S. EPERON, O. FELT-BAEYENS, R. GURNY, S. SAGODIRA, P. BRETON and Y. GUEX-CROSIER
"Trans-scleral diffusion of triamcinolone acetonide"
Current Eye Research, 30, 355-361 (2005)

S. MEHIER-HUMBERT and R.H. GUY
"Physical methods for gene transfer: Improving the kinetics of gene delivery into cells"
Advanced Drug Delivery Reviews, 57, 733-753 (2005)

N. MERCLIN, J. BENDER, E. SPARR, R.H. GUY, H. EHRSSON and S. ENGSTRÖM
"Transdermal delivery from a lipid sponge phase-iontophoretic and passive transport in vitro of 5-aminolevulinic acid and ist methyl ester"
Journal of Controlled Release, 100, 191-198 (2005)

M.A.H. CAPELLE, P. BRÜGGER and T. ARVINTE
"Spectroscopic characterization of antibodies adsorbed to aluminium adjuvants: correlation with antibody vaccine immunogenicity"
Vaccine, 23, 1686-1694 (2005)

U. BILATI, E. ALLEMANN and E. DOELKER
"Poly(D,L-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method-processing and formulation issues for enhanced entrapment efficiency"
Journal of Microencapsulation, 22 (2), 205-214 (2005)

F.LALLEMAND, P. FURRER, O. FELT-BAEYENS, M. GEX-FABRY, J.-M. DUMONT, K. BESSEGHIR and R. GURNY
"A novel water-soluble cyclosporine A prodrug: Ocular tolerance and in vivo kinetics"
International Journal of Pharmaceutics, 295, 7-14 (2005)

Y.N.KONAN-KOUAKOU, R. BOCH, R. GURNY and E. ALLEMANN
"In vitro and in vivo activities of verteporfin-loaded nanoparticles"
Journal of Controlled Releasse, 103, 83-91 (2005)

U. BILATI, C. PASQUARELLO, G.L. CORTHALS, D.F. HOCHSTRASSER, E. ALLEMANN and E. DOELKER
"Matrix-assisted desorption/ionization time-of-flight mass spectrometry for quantation and molecular stability assessment of insulin entrpped within PLGA nanoparticles"
Journal of Pharmaceutical Sciences, 94 (3), 688-694 (2005)

U. BILATI, E.ALLEMANN and E. DOELKER
"Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles"
European Journal of Pharmaceutics and Biopharmaceutics, 59, 375-388 (2005)

F. DELIE and M.J. BLANCO-PRIETO
"Polymeric particulates to improve oral bioavailability of peptide drugs"
Molecules, 10, 65-80 (2005)

F. LALLEMAND, O. FELT-BAEYENS. S. RUDAZ, A.R. HAMEL, F. HUBLER, R. WENGER, M.MUTTER, K. BESSEGHIR and R. GURNY
"Conversion of cyclosporine A prodrugs in human tears vs rabbits tears"
European Journal of Pharmaceutics and Biopharmaceutics, 59, 51-56 (2005)

U. BILATI, E. ALLEMANN and E. DOELKER
"Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles"
European Journal of Pharmaceutics and Biopharmaceutics, 24, 67-75 (2005)

J. BERGER, M. REIST, A. CHENITE, O. FELT-BAEYENS, J.M. MAYER and R. GURNY
"Pseudo-thermosetting chitosan hydrogels for biomedical application"
International Journal of Pharmaceutics, 288, 17-25 (2005)

V. WASCOTTE, B. LEBOULANGER, R.H. GUY and M.B. DELGADO-CHARRO
"Reverse iontophoresis of lithium: electrode formulation using a thermoreversible polymer"
European Journal of Pharmaceutics and Biopharmaceutics, 59, 237-240 (2005)

A. SIEG, R.H. GUY and M.B. DELGADO-CHARRO
"Noninvasive glucose monitoring by reverse iontophoresis in vivo : Application of the internal standard concept"
Clinical Chemistry, 50:8, 1383-1390 (2004)

B. LEBOULANGER, J.-M. AUBRY, G. BONDOLFI, R.H. GUY and M.B. DELGADO-CHARRO
"Lithium monitoring by reverse iontophoresis in vivo "
Clinical Chemistry, 50:11, 2091-2100 (2004)

N. SEKKAT, Y.N. KALIA and R.H. GUY
"Development of an in vitro model for premature neonatal skin: Biophysical characterization using transepidermal water loss"
Journal of Pharmaceutical Sciences, 93 (12), 2936-2940 (2004)

N. SEKKAT, Y.N. KALIA and R.H. GUY
"Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates"
Pharmaceutical Research, 21 (8), 1390-1397 (2004)

B. LEBOULANGER, R.H. GUY and M.B. DELGADO-CHARRO
"Non-invasive monitoring of phenytoin by reverse iontophoresis"
European Journal of Pharmaceutics Sciences, 22, 427-433 (2004)

N. MERCLIN, J. BENDER, E. SPARR, R.H. GUY, H. EHRSSON and S. ENGSTRÖM
"Transdermal delivery from a lipid sponge phase-iontophoretic and passive transport in vitro of 5-aminolevulinic acid and ist methyl ester"
Journal of Controlled Releasse, 100, 191-198 (2004)

R. ALVAREZ-ROMAN, A. NAIK, Y.N. KALIA, R.H. GUY and H. FESSI
"Enhancement of topical delivery from biodegradable nanoparticles"
Pharmaceutical Research, 21 (10) 1818-1825 (2004)

R. ALVAREZ-ROMAN, A. NAIK, Y.N. KALIA, R.H. GUY and H. FESSI
"Skin penetration and distribution of polymeric nanoparticles"
Journal of Controlled Release, 99, 53-62 (2004)

A. SIEG, R.H.GUY and M.B. DELGADO-CHARRO
"Simultaneous extraction of urea and glucose by reverse iontophoresis in vivo"
Pharmaceutical Research, 21 (10), 1805-1810 (2004)

A. SIEG, R.H. GUY and M.B. DELGADO-CHARRO
"Electroosmosis in transdermal iontophoresis: implications for noninvasive and calibration-free glucose monitoring"
Biophysical Journal, 87 (November), 3344-3350 (2004)

A. VARGAS, B. PEGAZ, E. DEBEFVE, Y. KONAN-KOUAKOU, N. LANGE, J.-P. BALLINI, H. van den BERGH, R. GURNY and F.DELIE
"Improved photodynamic activity of porphyrin loaded into nanoparticles: as in vivo evaluation using chick embryos"
International Journal of Pharmaceutics, 286, 131-145 (2004)

R. ALVAREZ-ROMAN, A. NAIK, Y.N. KALIA, H. FESSI and R.H. GUY
"Visualization of skin penetration using confocal laser scanning microscopy"
European Journal of Pharmaceutics and Biopharmaceutics, 58, 301-316 (2004)

F. LALLEMAND, F. BEHAR-COHEN, O. FELT-BAEYENS, S. RUDAZ, P. FURRER, K. BESSEGHIR, J.-M. DUMONT and R. GURNY
"Cyclosporine A prodrug for topical delivery to the eye"
Proceed 5th International Symposium, Monte Carlo, Monaco, pp 105-109 (2004)

O. FELT-BAEYENS, E. EPERON, P. MORA, D. LIMAL, S.SAGODIRA, P. BRETON, Y. GUEX-CROSIER and R. GURNY
"Scleral implants: A potential route of administration?"
Proceed 5th International Symposium, Monte Carlo, Monaco, pp 41-46 (2004)

S. COLLAUD, A. JUZENIENE, J. MOAN and N. LANGE
"On the selectivity of 5-aminolevulinic acid-induced protoporphyrin IX formation"
Current Medicinal Chemistry - Anti-Cancer Agents, 4, 301-316 (2004)

L. NOBS, F. BUCHEGGER, R. GURNY and E. ALLEMANN
"Poly(lactic acid) nanoparticles labeled with biologically active NeutravidinTM for active targeting"
European Journal of Pharmaceutics and Biopharmaceutics, 58, 483-490 (2004)

T. ARVINTE, T.T.T. BUI, A.A. DAHAB, B. DEMEULE, A. F. DRAKE, D. ELHAG and P. KING
"The multi-mode polarization modulation spectrometer: part. 1: simultaneous detection of absorption, turbidity, and optical activity" 
Analytical Biochemistry, 332, 46-57 (2004)

T. TRIMAILLE, M. MÖLLER and R. GURNY
"Synthesis and ring-opening polymerization of new monoalkyl-substituted lactides" 
Journal of Polymer Science: Part A: Polymer Chemistry, 42, 4379-4391 (2004)

E. DOELKER and D. MASSUELLE
"Benefits of die-wall instrumentation for research and development in tabletting" 
European Journal of Pharmaceutics and Biopharmaceutics, 58(2), 427-444 (2004)

S. GALINDO-RODRIGUEZ, E. ALLÉMANN, H. FESSI and E. DOELKER
"Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion, and nanoprecipitation methods" 
Pharmaceutical Research, 21(8), 1428-1439 (2004)

M.B. DELGADO-CHARRO and R.H. GUY
"Transdermal reverse iontophoresis of valproate: a noninvasive method for therapeutic drug monitoring" 
Pharmaceutical Research, 20(9), 1508-1513 (2004)

H.A. AYALA-BRAVO, D. QUINTANAR-GUERRERO, A. NAIK, Y.N. KALIA, J. M. CORNEJO-BRAVO and A.GANEM-QUINTANAR
"Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability" 
Pharmaceutical Research, 20(8), 1267-1273 (2004)

B. LEBOULANGER, M. FATHI, R.H. GUY and M. B. DELGADO-CHARRO
"Reverse iontophoresis as a noninvasive tool for lithium monitoring and pharmacokinetic profiling" 
Pharmaceutical Research, 21(7), 1214-1222 (2004)

S. GEINOZ, R.H. GUY, B. TESTA and P.-A. CARRUPT
"Quantitative structure-permeation relationships (QSPeRs) to predict skin permeation: a critical evaluation" 
Pharmaceutical Research, 21(1), 83-92 (2004)

Y. N. KALIA, A. NAIK, J. GARRISON and R.H. GUY
"Iontophoretic drug delivery" 
Advanced Drug Delivery Reviews, 56, 619-658 (2004)

L. NOBS, F. BUCHEGGER, R. GURNY and E. ALLÉMANN
"Current methods for attaching targeting ligands to liposomes and nanoparticles" 
Journal of pharmaceutical sciences, 93(8), 1980-1992 (2004)

L. BAYDOUN, P. FURRER, R. GURNY and C. MÜLLER-GOYMANN
"New surface-active polymers for ophthalmic formulations: evaluation of ocular tolerance" 
European Journal of Pharmaceutics and Biopharmaceutics, 58, 169-175 (2004)

G. SCHWACH, N. OUDRY, J.-P. GILIBERTO, P. BROQUA, M. LÜCK, H. LINDNER and R. GURNY
"Biodegradable PLGA microparticles for sustained release of a new GnRH antagonist: part II. in vivo performance" 
European Journal of Pharmaceutics and Biopharmaceutics, 57, 441-446 (2004)

O. JORDAN, E. DOELKER, N. DEFABIANI, A. CAVIEZEL and C. ISELIN
"Novel injectable urethral bulking agents for the treatment of urinary incontinence" 
Journal of Materials Science: Materials in Medicine, 15, 519-522 (2004)

C. CURDY, A. NAIK, Y. N. KALIA, I. ALBERTI and R. H. GUY
"Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo
International Journal of Pharmaceutics, 271, 251-256 (2004)

R. FONSECA VIANNA LOPEZ, N. LANGE, R. GUY and M.V. LOPES BADRA BENTLEY
"Photodynamic therapy of skin cancer: controlled drug delivery of 5-ALA and its esters" 
Advanced Drud Delivery Reviews, 56, 77-94 (2004)

J. BERGER, M. REIST, J.M. MAYER, O. FELT and R. GURNY
"Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications" 
European Journal of Pharmaceutics and Biopharmaceutics, 57, 35-52  (2004)

J. BERGER, M. REIST, J.M. MAYER, O. FELT, N.A. PEPPAS and R. GURNY
"Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications" 
European Journal of Pharmaceutics and Biopharmaceutics, 57, 19-34  (2004)

G. MERINO, Y.N. KALIA and R.H. GUY
"Ultrasound-enhanced transdermal transport" 
Journal of Pharmaceutical Sciences, 92(6), 1125-1137 (2003)

F. SCARMATO DE ROSA, A.C. TEDESCO, R.F. VIANNA LOPEZ, M.B. RIEMMA PIERRE, N. LANGE, J. MALDONADO MARCHETTI, J.C.GOMES ROTTA and M.V. LOPES BADRA BENTLEY
"In vitro skin permeation and retention of 5-aminolevulinic acid ester derivatives for photodynamic therapy" 
Journal of Controlled Release, 89, 261-269 (2003)

R. ALVAREZ-ROMÁN, G. MERINO, Y.N. KALIA, A. NAIK and R.H. GUY
"Skin permeability enhancement by low frequency sonophoresis: Lipid extraction and transport pathways" 
Journal of Pharmaceutical Sciences, 92 (6), 1138-1146 (2003)

A. LUZARDO-ALVAREZ, M. BEGOÑA-CHARRO and J. BLANCO-MÉNDEZ
"In vivo iontophoretic administration of ropinirole hydrochloride" 
Journal of Pharmaceutical Sciences, 92 (12), 2441-2448 (2003)

A. SIEG, R. H. GUY and M. B. DELGADO-CHARRO
"Reverse iontophoresis for noninvasive glucose monitoring: The internal standard concept" 
Journal of Pharmaceutical Sciences, 92 (11) 2295-2302 (2003)

F. LALLEMAND, O. FELT-BAEYENS, K. BESSEGHIR, F. BEHAR-COHEN and R. GURNY
"Cyclosporine A delivery to the eye: A pharmaceutical challenge" 
European Journal of Pharmaceutics and Biopharmaceutics, 56, 307-318  (2003)

G. SCHWACH, N. OUDRY, S. DELHOMME, M. LÜCK, H. LINDNER and R. GURNY
"Biodegradable microparticles for sustained release of a new GnRH antagonist- part I: screening commercial PLGA and formulation technologies" 
European Journal of Pharmaceutics and Biopharmaceutics, 56 (3), 327-336 (2003)

S. EINMAHL, S. PONSART, R. A. BEJJANI, F. D'HERMIES, M. SAVOLDELLI, J. HELLER,  C. TABATABAY, R. GURNY and F. BEHAR-COHEN
"Ocular biocompatibility of a poly(ortho ester) characterized by autocatalyzed degradation" 
Journal of Biomedical Materials Research, 67A(1), 44-53 (2003)

Y.N. KONAN, J. CHEVALLIER, R. GURNY and E. ALLEMANN
"Encapsulation of THPP into nanoparticles: Cellular uptake subcellular localization and effect of serum on photodynamic activity" 
Photochemistry and Photobiology, 77 (6), 638-644 (2003) 

C.A. NGUYEN, E. ALLEMANN, G. SCHWACH, E. DOELKER and R. GURNY
"Synthesis of a novel fluorescent poly(d,l-lactide) end-capped with 1-pyrenebutanol used for the preparation of nanoparticles" 
European Journal of Pharmaceutical Sciences, 20 (2), 217-222 (2003)

J.-L. BOURGES, S. E. GAUTIER, F. DELIE, R. A. BEJJANI, J.-C. JEANNY, R. GURNY, D. BENEZRA and F. F. BEHAR-COHEN
"Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles" 
Investigative Ophthalmology & Visual Science, 44 (8), 3562-3569 (2003)

S. CAPANCIONI, K. SCHWACH-ABDELLAOUI, W. KLOETI, W. HERRMANN, H. BROSIG, H.-H. BORCHERT, J. HELLER and R. GURNY
"In vitro monitoring of poly(ortho ester) degradation by electron paramagnetic resonance imaging". 
Macromolecules, 36, 6135-6141 (2003)

Y.N. KONAN, M. BERTON, R. GURNY and E. ALLÉMANN
"Enhanced photodynamic activity of meso-tetra(4-hydroxyphenyl)porphyrin by incorporation into sub-200 nm nanoparticles" 
European Journal of Pharmaceutical Sciences, 18, 241-249 (2003)

G. MERINO, Y. N. KALIA, M. B. DELGADO-CHARRO, R. O. POTTS and R. GUY
"Frequency and thermal effects on the enhancement of transdermal transport by sonophoresis" 
Journal of Controlled Release, 88, 85-94 (2003)

R.V. LOPEZ, M.V. L. B. BENTLEY, M.B. DELGADO-CHARRO and R. GUY
"Optimization of aminolevulinic acid delivery by iontophoresis" 
Journal of Controlled Release, 88, 65-70 (2003)

R.V. LOPEZ, M. V. L. B. BENTLEY, M.B. DELGADO-CHARRO, D. SALOMON, H. van den  BERGH, N. LANGE and R. GUY
"Enhanced delivery of 5-Aminolevulinic Acid Esters by iontophoresis in vitro"
Photochemistry and Photobiology, 77 (3), 304-308 (2003)

U. BILATI, E. ALLEMANN and E. DOELKER
"Sonication parameters for the preparation of biodegradable nanocapsules of controlled size by the double emulsion method" 
Pharmaceutical Development and Technology, 8 (1),1-9 (2003)

C.A. NGUYEN, E. ALLÉMANN, G. SCHWACH, E. DOELKER and R. GURNY
"Cell interaction studies of PLA-MePEG nanoparticles" 
International Journal of Pharmaceutics, 254, 69-72 (2003)

Y.N. KONAN, R. CERNY, J. FAVET, M. BERTON, R. GURNY and E. ALLÉMANN
"Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy" 
European Journal of Pharmaceutics and Biopharmaceutics, 55, 115-124 (2003)

L. NOBS, F. BUCHEGGER, R. GURNY and E. ALLEMANN
"Surface modification of poly(lactic acid) nanoparticles by covalent attachment of thiol groups by means of three methods" 
International Journal of Pharmaceutics, 250, 327-337 (2003)

N. SEKKAT, Y.N. KALIA and R.H. GUY
"Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo"
Journal of Pharmaceutical Sciences, 91, 11 (2002)

M.B. REDDY, A.L. STINCHCOMB, R.H. GUY and A.L. BUNGE
"Determining dermal absorption parameters in vivo from tape strip data" 
Pharmaceutical Research, vol. 19, 3 (2002)

O. FELT-BAEYENS and R. GURNY
"Bioadhesive Ophthalmic Drug Insert (BODI)" 
in: Drugs and the pharmaceutical sciences, volume 126, edited by M.J. Rathbone and al. 
Modified-release drug delivery technology, 28, 341-347 (2002)

V. BAEYENS, O. FELT-BAEYENS, S. ROUGIER, S. PHEULPIN, B. BOISRAME and R. GURNY
"Clinical evaluation of bioadhesive ophthalmic drug inserts (BODIÒ) for the treatment of external ocular infections in dogs" 
Journal of Controlled Release, 85, 163-168 (2002)

J. HELLER, J. BARR, S. Y. NG, H.-R. SHEN, K. SCHWACH-ABDELLAOUI, R. GURNY, N. VIVIEN-CASTIONI, P. J. LOUP, P. BAEHNI and A. MOMBELLI
"Poly(ortho esters): synthesis, characterization, properties and uses" 
Advanced Drug Delivery Reviews, 54 (7), 1015-1039 (2002)

K. SCHWACH-ABDELLAOUI, M. MOREAU, M. SCHNEIDER, B. BOISRAME and R. GURNY
"Controlled delivery of metoclopramide using an injectable semi-solid poly(ortho ester) for veterinary application" 
International Journal of Pharmaceutics, 248, 31-37 (2002)

K. SCHWACH-ABDELLAOUI, P. J. LOUP, N. VIVIEN-CASTIONI, A. MOMBELLI, P. BAEHNI, J. BARR, J. HELLER and R. GURNY
"Bioerodible injectable poly(ortho ester) for tetracycline controlled delivery to periodontal pockets: preliminary trials in humans" 
AAPS PharmSci, 4(4), article 20 (2002)

M. RAHMOUNI, V. LENAERTS, D. MASSUELLE, E. DOELKER and J.-C. LEROUX
"Influence of physical parameters and lubricants on the compaction properties of granulated and non-granulated cross-linked high amylose starch" 
Chem. Pharm. Bull., 50 (9), 1155-1162 (2002)

J. HELLER, J. BARR, S.Y. NG, H.-R. SHEN, K. SCHWACH-ABDELLAOUI, R. GURNY, N. VIVIEN-CASTIONI, P.J. LOUP, P. BAEHNI and A. MOMBELLI
"Development and application of injectable poly(ortho esters) for pain control and peridontal treatment" 
Biomaterials, 23, 4397-4404 (2002)

A. GANZA-GONZALEZ, S. ANGUIANO-IGEA, F.J. OTERO-ESPINAR, J. BLANCO-MENDEZ and P. BURI
"Polyacrylate-based microparticles for sustained release of metoclopramide" 
S.T.P. Pharma Sciences, 12(2), 103-107 (2002)

N. SEKKAT, A. NAIK, Y.N. KALIA, P. GLIKFELD and R.H. GUY
"Reverse iontophoretic monitoring in premature neonates: feasibility and potential" 
Journal of Controlled Release, 81, 83-89 (2002)

E. DOELKER
"Modifications cristallines and transformations polymorphes au cours des opérations galéniques" 
Ann. Pharm. Fr., 60, 161-176 (2002)

S. EINMAHL, M. SAVOLDELLI, F. D'HERMIES, C. TABATABAY, R. GURNY and F. BEHAR-COHEN
"Evaluation of a novel biomaterial in the suprachoroidal space of the rabbit eye"
Investigative Ophthalmology & Visual Science, 43(5), 1533-1539 (2002)

N. DUJARDIN, E. STAES, Y. KALIA, P. CLARYS, R. GUY and V. PREAT
" In vivo assessment of skin electroporation using square wave pulses"
Journal of Controlled Release, 79, 219-227 (2002)

N. GOUBET, C. RATTAZ, V. PIERRAT, E. ALLEMANN, A. BULLINGER and P. LEQUIEN
"Olfactory familiarization and discrimination in preterm and full-term newborns"
INFANCY, 3(1), 53-75 (2002)

P. FURRER, J.M. MAYER and R. GURNY
"Ocular tolerance of preservatives and alternatives"
European Journal of Pharmaceutics and Biopharmaceutics, 53, 263-280 (2002)

J. HELLER, J. BARR, S. NG, H.-R. SHEN, R. GURNY, K. SCHWACH-ABDELLAOUI, A. ROTHEN-WEINHOLD and M. van de WEERT
"Development of poly(ortho esters) and their application for bovine serum albumin and bupivacaine delivery"
Journal of Controlled Release, 78, 133-141 (2002)

C. A. NGUYEN, G. SCHWACH, E. ALLEMANN, T. ARVINTE, E. DOELKER and R. GURNY
"PLA-PEG nanoparticles: copolymerization, cell interaction studies and surface characterization of particles"
Proc. 4th World Meeting ADRITELF/APGI/APV, 711-712, Florence (8/11 April 2002)

L. NOBS, F. BUCHEGGER, R. GURNY and E. ALLEMANN
"Preparation of avidin-labeled poly(lactic acid) nanoparticles"
Proc. 4th World Meeting ADRITELF/APGI/APV, 715-716, Florence (8/11 April 2002)

Y.N. KONAN, M. BERTON, R. GURNY and E. ALLEMANN
"Improving the photodynamic activity of m-THPP by incorporation into sub-200 nm nanoparticles"
Proc. 4th World Meeting ADRITELF/APGI/APV, 749-750, Florence (8/11 April 2002)

U. BILATI, E. ALLEMANN and E. DOELKER
"Peptide- and protein-loaded PLGA nanocapsules using the double emulsion method.Optimization of sonication parameters"
Proc. 4th World Meeting ADRITELF/APGI/APV, 759-760, Florence (8/11 April 2002)

S. CAPANCIONI, K. SCHWACH-ABDELLAOUI, P. ZANELLO, J. GUYONNET, V. KALTSATOS and R. GURNY
"Semi-solid autocatalyzed poly(ortho ester) as a new veterinary drug delivery system for estrus synchronization in ewes"
Proc. 4th World Meeting ADRITELF/APGI/APV, 1539-1540, Florence (8/11 April 2002)

I. DIAZ DEL CONSUELO, Y. KALIA, M. PELLETIER, P. BURI and F. FALSON
"Permeation studies of ethanol through the pig buccal mucosa"
Proc. 4th World Meeting ADRITELF/APGI/APV, 1059-1060, Florence (8/11 April 2002)

M. RAHMOUNI, V. LENAERTS, D. MASSUELLE, E. DOELKER and J.-C. LEROUX
"Compaction properites of granulated and non granulated Contramid R "
Proc. 4th World Meeting ADRITELF/APGI/APV, 223-224, Florence (8/11 April 2002)

F. VEUILLEZ, F. FALSON RIEG, R.H. GUY, J. DESHUSSES and P. BURI
"Permeation of a myristoylated dipeptide across the buccal mucosa: topological distribution and evaluation of tissue integrity"
International Journal of Pharmaceutics, 231, 1-9 (2002)

O. FELT, S. EINMAHL, R. GURNY, P. FURRER and V. BAEYENS
"Polymeric systems for ophthalmic drug delivery"
in: Polymeric Biomaterials, ed. S. Dumitriu, 377-421 (2002)

Y.N. KONAN, R. GURNY and E. ALLEMANN
"Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles"
International Journal of Pharmaceutics., 233 (1-2), 239-252 (2002)

C. CURDY, Y.N. KALIA and R.H. GUY
"Post-iontophoresis recovery of human skin impedance in vivo "
European Journal of Pharmaceutics and Biopharmaceutics, 53, 15-21 (2002)

F. MOTTU, D.A. RUFENACHT, A. LAURENT and E. DOELKER
"Iodine-containing cellulose mixed esters as radiopaque polymers for direct embolization of cerebral aneurysms and arteriovenous malformations"
Biomaterials, 23 (1), 121-131 (2002)

Y. N. KONAN, R. GURNY and E. ALLEMANN
"State of the art in the delivery of photosensitizers for photodynamic therapy"
Journal of Photochemistry and Photobiology B: Biology, 66, 89-106 (2002)

P. FURRER, J.M. MAYER, B. PLAZONNET and R.GURNY
"Ocular tolerance of absorption enhancers in ophthalmic preparations"
AAAPS PharmSci, 4 (2), 1-5 (2002)

C. CURDY, Y.N. KALIA and R.H. GUY
"Non-invasive assessment of the effects of iontophoresis on human skin in-vivo "
Journal of Pharmacy and Pharmacology, 53, 769-777 (2001)

Y. N. KALIA, I. ALBERTI, A. NAIK and R.H. GUY
"Assessment of topical bioavailability in vivo : the importance of stratum corneum thickness"
Skin Pharmacol Appl Skin Physiol, 14 (suppl 1), 82-86 (2001)

C. CURDY, Y. N. KALIA, A. NAIK and R. H. GUY
"Piroxam delivery into human stratum corneum in vivo : iontophoresis versus passive diffusion"
Journal of Controlled Release, 76, 73-79 (2001)

M. B. DELGADO-CHARRO and R.H. GUY
"Transdermal iontophoresis for controlled drug delivery and non-invasive monitoring"
S.T.P. Pharma Sciences, 11 (6), 403-414 (2001)

A. ROTHEN-WEINHOLD, J. BARR, S.Y. NG, H.-R. SHEN, R. GURNY and J. HELLER
"Protein release from poly(ortho ester) extruded rods"
Macromol. Symp., 172, 67-72 (2001)

R.F.V. LOPEZ, M.V.L.B. BENTLEY, M.B. DELGADO-CHARRO and R.H. GUY
"Iontophoretic delivery of 5-aminolevulinic acid (ALA): effect of pH"
Pharmaceutical Research, 18(3), 311-315 (2001)

A. LUZARDO-ALVAREZ, M.B. DELGADO-CHARRO and J. BLANCO-MENDEZ
"Iontophoretic delivery of ropinirole hydrochloride: effect of current density and vehicle formulation"
Pharmaceutical Research, 18(12), 1714-1720 (2001)

I. ALBERTI, Y.N. KALIA, A. NAIK and R.H. GUY
"Assessment and prediction of the cutaneous bioavailability of topical terbinafine, in vivo , in man"
Pharmaceutical Research, 18 (10), 1472-1475 (2001)

C. CURDY, Y.N. KALIA and R.H. GUY
"Non-invasive assessment of the effects of iontophoresis on human skin in-vivo"
Journal of Pharmacy and Pharmacology, 53, 769-777 (2001)

K. MOSER, K. KRIWET, Y.N. KALIA and R.H. GUY
"Stabilization of supersaturated solutions of a lipophilic drug for dermal delivery"
International Journal of Pharmaceutics, 224, 169-176 (2001)

K. MOSER, K. KRIWET, Y.N. KALIA and R.H. GUY
"Enhanced skin permeation of a lipophilic drug using supersaturated formulations"  Journal of Controlled Release, 73, 245-253 (2001)

I. ALBERTI, Y.N. KALIA, A. NAIK, J.D. BONNY and R.H. GUY
"In vivo assessment of enhanced topical delivery of terbinafine to human stratum corneum"
Journal of Controlled Release, 71, 319-327 (2001)

I. ALBERTI, Y.N. KALIA, A. NAIK, J.D. BONNY and R.H. GUY
"Effect of ethanol and isopropyl myristate on the availability of topical terbinafine in human stratum corneum, in vivo "
International Journal of Pharmaceutics, 219, 11-19 (2001)

O. FELT, R. GURNY, P. BURI and V. BAEYENS
"Delivery of antibiotics to the eye using a positively charged polysaccharide as vehicle"
AAPS PharmSci., 3 (4), article 34 (2001)

M.J. ALVAREZ-FIGUEROA, M.B. DELGADO-CHARRO and J. BLANCO-MENDEZ
"Passive and iontophoretic transdermal penetration of methotrexate"
International Journal of Pharmaceutics, 212, 101-107 (2001)

R. ALVAREZ-ROMAN, G. BARRE, R.H. GUY and H. FESSI
"Biodegradable polymer nanocapsules containing a sunscreeen agent: preparation and photoprotection"
European Journal of Pharmaceutics and Biopharmaceutics, 52, 191-195 (2001)

Y.N. KALIA and R.H. GUY
"Modeling transdermal drug release"
Advanced Drug Delivery Reviews, 48, 159-172 (2001)

C. CURDY, Y.N. KALIA, A. NAIK and R.H. GUY
"Piroxicam delivery into human stratum corneum in vivo : iontophoresis versus passive diffusion"
Journal of Controlled Release, 76, 73-79 (2001)

D. MARRO, R.H. GUY and M.B. DELGADO-CHARRO
"Characterization of the iontophoretic permselectivity properties of human and pig skin"
Journal of Controlled Release, 70, 213-217 (2001)

D. MARRO, Y.N. KALIA, M.B. DELGADO-CHARRO and R.H. GUY
"Optimizing iontophoretic drug delivery : identification and distribution of the charge-carrying species"
Pharmaceutical Research, 18 (12), 1709-1713 (2001)

D. MARRO, Y.N. KALIA, M.B. DELGADO-CHARRO and R.H. GUY
"Contributions of electromigration and electroosmosis to iontophoretic drug delivery"
Pharmaceutical Research, 18 (12), 1701-1708 (2001)

S. GALINDO, E. ALLEMANN, H. FESSI and E. DOELKER
"Physical characteristics of ibuprofen-loaded nanoparticles prepared by threee methods"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 499-500, San Diego (USA), 2001

M. BERTON, A. ROHMANN, M. JUNGHANS, D. LOCHMANN, CY A. STEIN, R. GURNY and A. ZIMMER
"Evaluation of nanoparticles containing complexed oligonucleotides for the delivery of antisense drugs"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 1207-1208, San Diego (USA), 2001

S. EINMAHL, F. BEHAR-COHEN, C. TABATABAY, D. CHAUVAUD and R. GURNY
"A novel route of ocular drug delivery: suprachoroidal injections of a sustained release system"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 293-294, San Diego (USA), 2001

L. NOBS, F. BUCHEGGER, R. GURNY and E. ALLÉMANN
"Surface modification of poly(lactic acid) nanoparticles with thiol functions"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 1364-1365, San Diego (USA), 2001

Y.N. KALIA, I. ALBERTI, A. NAIK and R.H. GUY
"Assessement of the cutaneous bioavailability of topically applied drugs"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 187-188, San Diego (USA), 2001

G. SCHWACH, N. OUDRY, P. BROQUA, H. LINDNER, M. LÜCK, J. ANDERSON and R. GURNY
"PLGA-based microparticles containing a hydrophilic GnRH antagonist of the new generation"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 890-891, San Diego (USA), 2001

A.G. SARRAF, F. BARJA, L. OUALI, E.G. SARRAF, R. GURNY and E. DOELKER
"Effect of polymer orientation induced by melt-extrusion on drug release"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 423-424, San Diego (USA), 2001

K. SCHWACH-ABDELLAOUI, P.J. LOUP, N. VIVIEN-CASTIONI, A. MOMBELLI, P. BAEHNI, J. HELLER and R. GURNY
"A novel bioerodible injectable system based on poly(ortho ester) for the adjunctive treatment of advanced periodontal disease"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 305-306, San Diego (USA), 2001

H. ADACHI, Y.N. KALIA, R.H. GUY, N. HIGO and A. NAIK
"Topical iontophoretic delivery of chlorhexidine"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 211-212, San Diego (USA), 2001

K. SCHWACH-ABDELLAOUI, V. KALTSATOS, M.MOREAU, B. BOISRAMÉ and R. GURNY
"Controlled delivery of an antiemetic agent using an injectable semi-solid poly(ortho ester) for the treatment of gastrointestinal disorder in dogs"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 1245-1246, San Diego (USA), 2001

R.F.V. LOPEZ, M.V.L.B. BENTLEY, M.B. DELGADO-CHARRO, D. SALOMON, H. van den BERGH, N. LANGE and R.H. GUY
"Iontophoretic delivery of 5-aminolevulinic acid (ALA) and a series of ALA esters into and through the skin"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 193-194, San Diego (USA), 2001

R.H. GUY, M.B. DELGADO-CHARRO and Y.N. KALIA
"Iontophoretic transport across the skin"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 183-184, San Diego (USA), 2001

N. SEKKAT, Y.N. KALIA and R.H. GUY
"Control of drug delivery across an impaired skin barrier by iontophoresis"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 185-186, San Diego (USA), 2001

F. VEUILLEZ, F. FALSON-RIEG, R.H. GUY, J. DESHUSSES and P. BURI
"Effect of ethanol on the diffusion of a myristoylated dipeptide across the pig buccal mucosa"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 179-180, San Diego (USA), 2001

R. ALVAREZ-ROMAN, G. BARRE, A. NAIK, Y. KALIA, R.H. GUY and H. FESSI
"Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection"
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 28, 497-498, San Diego (USA), 2001

K. MOSER, K. KRIWET, A. NAIK, Y.N. KALIA and R.H. GUY
"Passive skin penetration enhancement and its quantification in vitro "
European Journal of Pharmaceutics and Biopharmaceutics, 52(2), 103-112 (2001)

S. EINMAHL, K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Poly(ortho esters): Recent developments for biomedical applications"
Chimia, 55 (3), 218-222 (2001)

J. HELLER, J. BARR, S. NG, H.-R. SHEN, K. SCHWACH-ABDELLAOUI and R. GURNY
"Development of poly(ortho esters)"
dds&s, 1 (3), 79-84 (2001)

K. MOSER, K. KRIWET, C. FROEHLICH, Y.N. KALIA and R.H. GUY
"Supersaturation : enhancement of skin penetration and permeation of a lipophilic drug"
Pharmaceutical Research, 18 (7), 1006-1011 (2001)

M. BERTON, P. TURELLI, D. TRONO, Cy A. STEIN, E. ALLEMANN and R. GURNY
"Inhibition of HIV-1 in cell culture by oligonucleotide-loaded nanoparticles"
Pharmaceutical Research, 18 (8), 1096-1101 (2001)

J. FAVET, M.-L. CHAPPUIS and E. DOELKER
"A case study of preservation of semi-solid preparations using the European Pharmacopoeia test: comparative efficacy of antimicrobial agents in zinc gelatin" 
European Journal of Pharmaceutics and Biopharmaceutics, 52(2), 255-259 (2001)

S. EINMAHL,  F. BEHAR-COHEN, C. TABATABAY and R. GURNY
"Treatment of intraocular diseases with poly(ortho ester)-based drug delivery systems" 
Polymers in Medicine, Macromolecular Symposia, ed Wiley-VCH, J. Kahovec, 172, 73-86 (2001)

A.G. SARRAF, H. TISSOT, P. TISSOT, D. ALFONSO, R. GURNY and E. DOELKER
"Influence of hot-melt extrusion and compression molding on polymer structure organization, investigated by differential scanning calorimetry" 
J. Appl. Polym. Sci., 81(13), 3124-3132 (2001)

F. MOTTU, M.-J. STELLING, D.A. RUFENACHT and E. DOELKER
"Comparative hemolytic activity of undiluted organic water-miscible solvents for intravenous and intra-arterial injection" 
PDA  J. Pharm. Sci. Technol., 55 (1),16-23 (2001)

R.H. GUY, M.B. DELGADO-CHARRO and Y.N. KALIA
"Iontophorectic transport across the skin" 
Skin Pharmacology and Applied Skin Physiology, 14 (suppl. 1), 35-40 (2001)

F.F. BEHAR-COHEN, D. BENEZRA, S. EINMAHL and R. GURNY
"Challenges of intraocular drug delivery" 
European Pharmaceutical Review, Materials, 35-39 (2001)

F. DELIE, R. GURNY and A. ZIMMER
"Fluorescence correlation spectroscopy for the characterisation of drug delivery systems" 
Biological Chemistry, 382(3), 487-490 (2001)

I. BRIGGER, P. CHAMINADE, V. MARSAUD, M. APPEL, M. BESNARD, R. GURNY, M. RENOIR and P. COUVREUR
"Tamoxifen encapsulation within polyethylene glycol-coated nanospheres. A new antiestrogen formulation" 
International Journal of Pharmaceutics, 214(1-2), 37-42 (2001)

K. MOSER, K. KRIWET, C. FROEHLICH, A. NAIK, Y.N. KALIA and R.H. GUY
"Permeation enhancement of a highly lipophilic drug using supersaturated systems" 
Journal of Pharmaceutical Sciences, 90 (5), 607-616 (2001)

K. SCHWACH-ABDELLAOUI, A. MONTI, J. BARR, J. HELLER and R. GURNY
"Optimization of a novel bioerodible device based on auto-catalyzed poly(ortho esters for controlled delivery of tetracycline to periodontal pockets" 
Biomaterials, 22 (12), 1659-1666 (2001)

A. ROTHEN-WEINHOLD, K. SCHWACH-ABDELLAOUI, J. BARR, S.Y. NG, H.-R. SHEN, R. GURNY and J. HELLER
"Release of BSA from poly(ortho ester) extruded thin strands" 
Journal of Controlled Release, 71 (1), 31-37 (2001)

O. JORDAN, K. BARATH, K. TOKUNAGA, D. RÜFENACHT and E. DOELKER
"Implant technology for endovascular repair of cerebral aneurysm: required material characteristics" 
European Cells and Materials, 1(1), 41-42  (2001)

F. DE JAEGHERE, E. ALLÉMANN, E. DOELKER, R. GURNY, R. CERNY, B. GALLI, A. F. STEULET, I. MÜLLER and H. SCHÜTZ
"pH-dependent dissolving nano- and microparticles for improved peroral delivery of a highly lipophilic compound in dogs" 
AAPS PharmSci, 3 (1), article 8 (2001)

F. VEUILLEZ, Y.N. KALIA, Y. JACQUES, J. DESHUSSES and P. BURI
"Factors and strategies for improving buccal absorption of peptides" 
European Journal of Pharmaceutics and Biopharmaceutics, 51, 93-109 (2001)

F. DELIE, M. BERTON, E. ALLÉMANN and R. GURNY
"Comparison of two methods of encapsulation of an oligonucleotide into poly(D,L-lactic acid) particles" 
International Journal of Pharmaceutics, 214, 25-30 (2001)

S. EINMAHL, F. BEHAR-COHEN, F. D'HERMIES, S. RUDAZ, C. TABATABAY, G. RENARD and R. GURNY
"A new poly(ortho ester)-based drug delivery system as an adjunct treatment in filtering surgery" 
IOVS, 42 (3), 695-700 (2001)

P. FURRER, J. BERGER J. M. MAYER and R. GURNY
"Etude comparative de la tolérance oculaire de 3 spécialités à base de timolol: influence du conservateur sur la tolérance oculaire" 
J. Fr. Ophtalmol., 24 (1), 13-19 (2001)

B. BAROLI, A. LOPEZ-QUINTELA, B. DELGADO-CHARRO, A. M. FADDA and J. BLANCO-MENDEZ
"Microemulsions for topical delivery of 8-methoxsalen" 
Journal of Controlled Release, 69, 209-218 (2000)

C. CURDY, Y.N. KALIA, F. FALSON-RIEG and R.H. GUY
"Recovery of human skin impedance in vivo after iontophoresis : effect of metal ions" 
AAPS Pharmsci 2 (3), article 23, 1-7 (2000)

F. DE JAEGHERE, E. ALLÉMANN, J. FEIJEN, T. KISSEL, E. DOELKER and R. GURNY
"Freeze-drying and lyopreservation of diblock and triblock poly(lactic acid)-poly(ethylene oxide) (PLA-PEO) copolymer nanoparticles" 
Pharm. Dev. Technol., 5 (4), 473-483 (2000)

B.S. GREWAL, A. NAIK, W.J. IRWIN, G. GOORIS, C.J. DE GRAUW, H.G. GERRITSEN and J.A. BOUWSTRA
"Transdermal macromolecular delivery : real-time visualization of iontophoretic and chemically enhanced transport using two-photon excitation microscopy" 
Pharmaceutical Research, 17 (7), 788-795 (2000)

Y.N. KALIA, I. ALBERTI, N. SEKKAT, C. CURDY, A. NAIK and R.H. GUY
"Normalization of stratum corneum barrier function and transepidermal water loss in vivo
Pharmaceutical Research, 17 (9), 1148-1150 (2000)

C. FERRERO RODRIGUEZ, N. BRUNEAU, J. BARRA D. ALFONSO and E. DOELKER
"Hydrophilic cellulose derivatives as drug delivery carriers: Influence of substitution type on the properties of compressed matrix tablets" 
in: Handbook of Pharmaceutical Controlled Release Technology 
Donald L. Wise (ed), Marcel Dekker, New York, Basel, pp. 1-30 (2000) 

F. MOTTU, A. LAURENT, D. A. RÜFENACHT and E. DOELKER
"Organic solvents for pharmaceutical parenterals and embolic liquids: A review of toxicity data" 
PDA J. Pharm. Sci. Technol., 54 (6), 456-469 (2000)

A. GANEM-QUINTANAR, D. QUINTANAR-GUERRERO and P. BURI
"Monoolein: a review of the pharmaceutical applications" 
Drug Dev. Ind. Pharm., 26(8), 809-820 (2000)

P. FURRER, B. PLAZONNET, J. M. MAYER and R. GURNY
"Application of in vivo confocal microscopy to the objective evaluation of ocular irritation induced by surfactants" 
International Journal of Pharmaceutics, 207, 89-98 (2000)

S. Y. NG, H.-R. SHEN, J. BARR, A. ROTHEN-WEINHOLD, S. EINMAHL, K. SCHWACH-ABDELLAOUI, R. GURNY and J. HELLER
"Poly (ortho esters) - A versatile drug delivery system" 
Proceed. Int.'l Symp. Biomater. Drug Delivery Systems, Korea, 6-3,  31 (2000)

A. ROTHEN-WEINHOLD, J. HELLER, J. BARR and R. GURNY
"Poly (ortho esters) implants for the sustained delivery of a protein : farctors influencing the release behaviour of BSA in vitro
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 27, 968-969 (2000)

C. CURDY, Y.N. KALIA, A. NAIK and R.H. GUY
" In vivo evaluation of piroxicam delivery into the stratum corneum : iontophoresis versus passive diffusion" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 928-929 (2000)

A. GANEM-QUINTANAR, D. QUINTANAR-GUERRERO, P. BURI and  Y. JACQUES
"Permeability to fentanyl solutions and lipid composition of buccal epithelium surgically isolated versus heat-separated" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 27, 812-813 (2000)

S. DUMITRIU, N. BRUNEAU, H. FESSI and P. BURI
"Polyionic hydrogels as support for controlled release of nifedipine" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 27, 455-456 (2000)

Y. N. KONAN, E. ALLÉMANN and R. GURNY
"Preparation and characterization of sterile and freeze-dried SUB-200 nm nanoparticles" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 27, 321-322 (2000)

I. BRIGGER, D. DESMAËLE, P. CHAMINADE, M.T. PERACCHIA, J. D'ANGELO, R. GURNY, J.M. RENOIR and P. COUVREUR
"A novel analytical approach for the characterization of poly(MePEGcyanoacrylate-co-hexadecylcyanoacrylate) nanoparticles" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 27, 41-42 (2000)

A. DOLIWA, M.B. DELGADO-CHARRO, S. SANTOYO, P. YGARTUA and R.H. GUY
" In vitro iontophoretic delivery of piroxicam from hydroxypropyl- b -cyclodextrin - piroxicam complexes" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 898-899, Paris (France), 2000

N. DUJARDIN, Y.N. KALIA, E. STAES, A. BAREL, R.H. GUY and V. PREAT
" In vivo assessement of skin electroporation using square wave pulses" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 906-907, Paris (France), 2000

K. MOSER, K. KRIWET, C. FROEHLICH, Y.N. KALIA and R.H. GUY
"Effect of supersaturation on skin penetration and permeation of a lipophilic drug" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 167-168, Paris (France), 2000

E. SEGUNDO-PIÑON, Y. JACQUES, A. GANEM-QUINTANAR and D. QUINTANAR-GUERRERO
"Optimization of a process to obtain nanoparticles of triclosan for periodontal treatment" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 1138-1139, Paris (France), 2000

G. MERINO, M.B. DELGADO-CHARRO, Y.N. KALIA and R.H. GUY
"Mechanism of enhanced transdermal transport by low-frequency ultrasound: the role of local heating?" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 942-943, Paris (France), 2000

E. ALLÉMANN
"Polymeric nanoparticles - past, present and future" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 184-185 Paris (France), 2000

D. MARRO, M.B. DELGADO-CHARRO, Y.N. KALIA and R.H. GUY
"Optimizing iontophoretic drug delivery : identification and distribution of the charge-carrying species" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 938-939, Paris (France), 2000

R.F.V. LOPEZ, M.V.L.B. BENTLEY, M.B. DELGADO-CHARRO and R.H. GUY
"Iontophoretic delivery of 5-aminolevulinic acid (ALA): Effect of pH" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 896-897, Paris (France), 2000

N. SEKKAT, Y.N. KALIA and R.H. GUY
"Percutaneous absorption and perturbed barrier function: a model for transdermal delivery to the neonate?" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 165-166, Paris (France), 2000

A. LUZARDO-ALVAREZ, M.B. DELGADO-CHARRO and J. BLANCO-MENDEZ
"Iontophoretic delivery of ropinirole HCl: Effect of current density and vehicle formulation" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 159-160, Paris (France), 2000

D. MARRO, R.H. GUY and M.B. DELGADO-CHARRO
"Iontophoretic permselectivity of human skin: determination of the isoelectric point" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 27, 157-158, Paris (France), 2000

M. ZIGNANI, S. EINMAHL, V. BAEYENS, E. VARESIO, J.-L. VEUTHEY, J. ANDERSON, J. HELLER, C. TABATABAY and R. GURNY
"A poly(ortho ester) designed for combined ocular delivery of dexamethasone sodium phosphate and 5-fluorouracil : subconjunctival tolerance and in vitro release" 
European Journal of Pharmaceutics and Biopharmaceutics. 50, 251-255 (2000)

F. DE JAEGHERE, E. ALLÉMANN, F. KUBEL, B. GALLI, R. COZENS, E. DOELKER and R. GURNY
"Oral bioavailability of a poorly water soluble HIV-1 protease inhibitor incorporated into pH-sensitive particles : effect of the particle size and nutritional state" 
Journal of Controlled Release, 68, 291-298 (2000)

S.Y. NG, H.-R. SHEN, J. BARR, A. ROTHEN-WEINHOLD, S. EINMAHL, K. SCHWACH-ABDELLAOUI, R. GURNY and J. HELLER
"Poly(ortho esters) - A versatile drug delivery system" 
in : Biomaterials and Drug Delivery toward New Millenium, K.D. Park, I.C. Kwon, N. Yui, S.Y. Jeong, K. Park (éd.), Han Rim Won Publishing Co., Seoul, Korea, 147-156 (2000) 

V. BAEYENS, O. FELT, R. GURNY, F. F. BEHAR-COHEN, C. PERCICOT and A. RÉGNIER
"Design and development of controlled release veterinary drug delivery systems to the eye" 
in : Controlled Release Veterinary Drug Delivery : Biological and Pharmaceutical Considerations, M.J. Rathbone, R. Gurny (éd.), Elsevier, Amsterdam, 115-171 (2000)

J. FAVET, M.-L. CHAPPUIS and E. DOELKER
"Adaptation of the Ph. Eur. test for efficacy of antimicrobial preservation to zinc gelatin. A Case study for solid or semi-solid preparations" 
Pharmeuropa, 12 (3), 376-383 (2000)

A. ROTHEN-WEINHOLD, M. DAHN and R. GURNY
"Formulation and technology aspects of controlled drug delivery in animals" 
PSTT, 3 (7), 222-231 (2000)

M. ZIGNANI, T. LE MINH, S. EINMAHL, C. TABATABAY, J. HELLER, J. M. ANDERSON and R. GURNY
"Improved biocompatibility of a viscous bioerodible poly(ortho ester) by  controlling the environmental pH during degradation" 
Biomaterials, 21, 1773-1778 (2000)

K. SCHWACH-ABDELLAOUI, N. VIVIEN-CASTIONI and R. GURNY
"Local delivery of antimicrobial agents for the treatment of periodontal diseases" 
European Journal of Pharmaceutics and Biopharmaceutics, 50, 83-99 (2000)

J. BARRA, A. ULLRICH, F. FALSON-RIEG and E. DOELKER
"Color as an indicator of the organization and compactibility of binary powder mixes" 
Pharm. Dev. Technol., 5 (1), 87-94  (2000)

F. DE JAEGHERE, E. ALLÉMANN, J. FEIJEN, T. KISSEL, E. DOELKER and R. GURNY
"Cellular uptake of PEO surface-modified nanoparticles: evaluation of nanoparticles made of PLA:PEO diblock and triblock copolymers" 
J. Drug Target., 8 (3), 143-153 (2000)

O. FELT, A. CARREL, P. BAEHNI, P. BURI and R. GURNY
"Chitosan as tear substitute : A wetting agent endowed with antimicrobial efficacy" 
J. Ocul. Pharmacol. Ther., 16 (3), 261-270 (2000)

A. NAIK, Y.N. KALIA and R.H. GUY
"Transdermal drug delivery: overcoming the skin's barrier function" 
PSTT, 3(9), 318-326, 2000

R. PICHON, C. NUSSBAUMER, M. SALLIN and E. ALLÉMANN
"Perméabilité à la lumière de poches de protection des médicaments injectables : détermination par trois méthodes" 
J. Pharm. Clin., 19, 10-13 (2000)

A. ROTHEN-WEINHOLD, N. OUDRY, K. SCHWACH-ABDELLAOUI, S. FRUTIGER-HUGHES, G. J. HUGHES, D. JEANNERAT, U. BURGER, K. BESSEGHIR and R. GURNY
"Formation of peptide impurities in polyester matrices during implant manufacturing" 
European Journal of Pharmaceutics and Biopharmaceutics, 49, 253-257 (2000)

J. BARRA, M.-A. PENA and P. BUSTAMANTE
"Proposition of group molar constant for sodium to calculate the partial solubility parameters of sodium salts using the van Krevelen group contribution method" 
Eur. J. Pharm. Sci., 10, 153-161 (2000)

S. EINMAHL, F. BEHAR-COHEN, C. TABATABAY, M. SAVOLDELLI, F. D'HERMIES, D. CHAUVAUD, J. HELLER and R. GURNY
"A viscous bioerodible poly(ortho ester) as a new biomaterial for intraocular application" 
J. Biomed. Mater. Res., 50, 566-573 (2000)

J. BARRA, F. FALSON-RIEG and E. DOELKER
"Modified drug release from inert matrix tablets prepared from formulations of identical composition but different organisations" 
Journal of Controlled Release, 65, 419-428 (2000)

F. MOTTU, P. GAILLOUD, D. MASSUELLE, D.A. RÜFENACHT and E. DOELKER
"In vitro assessment of new embolic liquids prepared from preformed polymers and water-miscible solvents for aneurysm treatment" 
Biomaterials, 21, 803-811 (2000)

M. ANGELES PEÑA, Y. DAALI, J. BARRA and P. BUSTAMANTE
"Partial solubility parameters of lactose, mannitol and saccharose using the modified extended Hansen method and evaporation light scattering detection" 
Chem. Pharm. Bull., 48(2), 179-183 (2000)

J. ALVAREZ-FIGUEROA, M.B. DELGADO-CHARRO and J. BLANCO-MENDEZ
"Effect of current density and formulation on the iontophoretic delivery of methotrexate" 
3rd world meeting on pharmaceutics biopharmaceutics pharmaceutical technology, Berlin, 697-698 (3 to 6 april 2000)

C. CURDY, Y.N. KALIA, F. FALSON-RIEG and R.H. GUY
"Effect of metal ions on the recovery of human skin impedance in vivo after iontophoresis" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 391-392 (1999)

N. SEKKAT, R.H. GUY and Y.N. KALIA
"Comparing the barrier properties of in vitro porcine ear skin with human skin in vivo
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 427-428, Boston (USA), 1999

A. LOPEZ-CASTELLANO, R.H. GUY and M.B. DELGADO-CHARRO
"Effect of area on the iontophoretic transport of phenylalanine and propanolol across the skin" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 405-406, Boston (USA), 1999

I. ALBERTI, A. NAIK, Y.N. KALIA, J.-D. BONNY and R.H. GUY
" In vivo evaluation of topical delivery systems by Fourier transform infrared spectroscopy (FTIR)" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 475-476,1999

N. SEKKAT, R.H. GUY and Y.N. KALIA
"Developing in vitro models for skin barrier function in premature neonates" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 429-430,Boston (USA), 1999

G. MERINO, Y.N. KALIA, M.B. DELGADO-CHARRO, R.O. POTTS and R.H. GUY
"Sonophoresis: How does ultrasound enhance drug transport across the skin?" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 383-384,Boston (USA), 1999

D. MARRO, M.B. DELGADO-CHARRO, Y.N. KALIA and R.H. GUY
"Iontophoretic transport mechanisms: effect of background electrolyte and competing ions" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 94-95,Boston (USA), 1999

J. BARRA, P. BUSTAMANTE and E. DOELKER
"Optimisation des propriétés des excipients pour formes solides par le concept des énergie de surface and des paramètres de solubilité" 
S.T.P. Pharma, 9 (hors-série), 19-22 (1999)

J. BARRA, F. FALSON-RIEG and E. DOELKER
"Influence of the organization of binary mixes on their compactibility" 
Pharmaceutical Research, 16 (9), 1449-1455 (1999)

J. BARRA, F. LESCURE and E. DOELKER
"Taste masking as a consequence of the organisation of powder mixes" 
Pharm. Acta Helv., 74(1), 37-42 (1999)

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Bioerodible devices based on poly(ortho esters) for controlled delivery of tetracycline to periodontal pocket" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 697-698 (1999)

S. EINMAHL, F. BEHAR-COHEN, C. TABATABAY and R. GURNY
"Evaluation of poly(ortho ester) for intraocular application in rabbits: biocompatibility assessement and in vitro degradation" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 679-680 (1999)

J. ACEVEDO-PEÑA , Y.N. KALIA, P. BURI, R.H. GUY, D. QUINTANAR-GUERRERO and A. GANEM-QUINTANAR
"Enhancing effects of Azone R and 4-decyl-oxazolidin-2-one ex vivo skin permeation" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 481-482 (1999)

F. VEUILLEZ, J. DESHUSSES, F. FALSON and P. BURI
"Topological distribution of a myristoylated peptide throughout the pig buccal mucosa during permeation" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 339-340 (1999)

I. ROSENDO-VALDES, Y.N. KALIA, P. BURI, R.H. GUY, D. QUINTANAR-GUERRERO and A. GANEM-QUINTANAR
"Enhancing effect of 1-dodecylazacycloheptan-2-one(AzoneR) and 4-decyl-oxazolidin-2-one on drug absorption across the buccal" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 333-334 (1999)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, H. FESSI and E. DOELKER
"Pseudolatex preparation using a novel emulsion-diffusion process involving direct  displacement of partially water-miscible solvents by distillation" 
International Journal of Pharmaceutics., 188, 155-164 (1999)

M. BERTON, E. ALLÉMANN, CY A. STEIN and R. GURNY
"Highly loaded nanoparticulate carrier using an hydrophobic antisense  oligonuccleotide complex" 
Eur. J. Pharm. Sci., 9, 163-170 (1999)

J. HELLER, S.Y. NG, R-H SHEN, J. BARR, A. ROTHEN-WEINHOLD and R. GURNY
"Protein delivery from extruded poly(ortho esters)" 
Proceed. Asian Conference on Controlled Release, Hong Kong, , 132-133 (1999)

A. ROTHEN-WEINHOLD, K. BESSEGHIR and R. GURNY
"Production of biodegradable implants for the sustained release of pharmaceuticals" 
Proceed. Asian Conference on Controlled Release, Hong Kong, 72-73 (1999)

S. EINMAHL, F. BEHAR-COHEN, C. TABATABAY, D. CHAUVAUD, J. HELLER and R. GURNY
"Poly(ortho ester) : A new biocompatible intraocular drug delivery system" 
Proceed. Asian Conference on Controlled Release, Hong Kong, , 70-71 (1999)

R. GURNY, A. ROTHEN-WEINHOLD and K. BESSEGHIR
"Biodegradable implants" 
Proceed. Asian Conference on Controlled Release, Hong Kong, 46-47 (1999)

N.M. RANJHA and E. DOELKER
"pH-sensitive noncrosslinked poly(vinyl alcohol-co-acrylic acid) hydrogels for site  specific drug delivery" 
Saudi Pharm. J. 7(3), 137-143 (1999)

E. DOELKER
"Caractères physicochimiques des principes actifs. Leurs conséquences sur la  faisabilité et la stabilité des formes galéniques" 
S.T.P. Pharma Prat. 9, 399-409 (1999)

A. ROTHEN-WEINHOLD, K. BESSEGHIR, E. VUARIDEL, E. SUBLET, N. OUDRY, F. KUBEL and R. GURNY
"Injection-molding versus extrusion as manufacturing technique for the preparation  of biodegradable implants" 
European Journal of Pharmaceutics and Biopharmaceutics, 48, 113-121 (1999)

N.M. RANJHA and E. DOELKER
"pH-sensitive hydrogels for site-specific drug delivery. II. Drug release behaviour  from crosslinked alkyl acrylates/methacrylic acid copolymers" 
S.T.P. Pharma Sci. 9, 341-349 (1999)

N.M. RANJHA and E. DOELKER
"pH-sensitive hydrogels for site-specific drug delivery. I. Swelling behaviour of  crosslinked copolymers of acrylic and methacrylic acid" 
S.T.P. Pharma Sci. 9, 335-340 (1999)

J. BARRA, P. BUSTAMANTE and E. DOELKER
"Use of the solubility parameter and surface energy concepts in the formulation of  solid dosage forms" 
S.T.P. Pharma Sci., 9 293-305 (1999)

S. EINMAHL, M. ZIGNANI, E. VARESIO, J. HELLER, J.-L. VEUTHEY, C. TABATABAY and R. GURNY
"Concomitant and controlled release of dexamethasone and 5-fluorouracil from  poly(ortho ester)" 
International Journal of Pharmaceutics, 185, 189-198 (1999)

J. HELLER and R. GURNY
"Poly(ortho esters)" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz  (éd.), vol. 2, John Wiley & Sons, Inc, New York,  pp. 852-874, (1999)

F. DE JAEGHERE, E. DOELKER, and R. GURNY
"Nanoparticles" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz  (éd.), vol. 2, John Wiley & Sons, Inc, New York,  pp. 641-664, (1999)

O. FELT, V. BAEYENS, M. ZIGNANI, P. BURI and R. GURNY
"Mucosal drug delivery, ocular" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz (éd.), vol. 2, John Wiley & Sons, Inc, New York, pp. 605-626 (1999)

S. EINMAHL, A.A. DESHPANDE, C. TABATABAY and R. GURNY
"Mucosal drug delivery, intravitreal" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz (éd.), vol. 2, John Wiley & Sons, Inc, New York, pp. 564-592, (1999)

F. VEUILLEZ, J. DESHUSSES and P. BURI
"Synthesis and characterization of an acylated di-peptide (Myr-Trp-Leu) with  modified transmucosal transport properties" 
European Journal of Pharmaceutics and Biopharmaceutics, 48, 21-26 (1999)

F. MOTTU, D.A. RÜFENACHT and  E. DOELKER
"Radiopaque polymeric materials for medical applications. Current aspects of biomaterial research." 
Invest. Radiol. 34 (5), 323-335 (1999)

F. DE JAEGHERE, E. ALLÉMANN, J. FEIJEN, T. KISSEL, E. DOELKER and R. GURNY
"Cellular uptake of nanoparticles made of poly(lactic acid), poly(ethylene oxide)  diblock and triblock copolymers"
Proceed. Int.'l Control. Rel. Bioact. Mater. 26, 685-686 (1999)

A. ROTHEN-WEINHOLD, N. OUDRY, K. SCHWACH-ABDELLAOUI, S. FRUTIGER-HUGHES, G.J. HUGHES, K. BESSEGHIR and R. GURNY
"How to avoid the formation of peptide impurities during manufacturing of implants  by melt-extrusion ? " 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 681-682 (1999)

A. ZIMMER, F. DELIE-SALMON and R. GURNY
"Application of fluorescence correlation spectroscopy for the characterization of drug  delivery systems" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 671-672 (1999)

O. FELT, C. MICHEL, P. BURI and R. GURNY
"Gamma scintigraphy as tool for the evaluation of precorneal residence time :  influence of the methodology" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 615-616 (1999)

G. MOLINARO, A. ADAM, M. ZIGNANI, J. TAILLEFER, K. SCHWACH-ABDELLAOUI, R. GURNY and J.C. LEROUX
"Evaluation of the local and systemic inflammatory responses induced by the  subcutaneous injection of different biopolymers" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 611-612 (1999)

F. DE JAEGHERE, E. ALLÉMANN, J. FEIJEN, E. DOELKER and R. GURNY
"Freeze-drying of PLA-PEO nanoparticles - from basic principles to rational optimization" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 573-574 (1999)

J. HELLER, S.Y. NG, J. BARR, R. GURNY, K. SCHWACH-ABDELLAOUI and E. SCHACHT
"Erosion, properties and drug release from a new family of poly(ortho esters)" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 232-233 (1999)

O.  FELT, P. FURRER, J.M. MAYER, B. PLAZONNET, P. BURI and R. GURNY
"Topical use of chitosan in ophthalmology : tolerance assessment and evaluation of  precorneal retention" 
International Journal of Pharmaceutics, 180 (2), 185-193 (1999)

F. DE JAEGHERE, E. ALLÉMANN, J.-C. LEROUX, W. STEVELS, J. FEIJEN, E.DOELKER and R. GURNY
"Formulation and lyoprotection of poly(lactic acid-co-ethylene oxide) nanoparticles :  influence on physical stability and in vitro cell uptake" 
Pharmaceutical Research, 16(6), 859-866 (1999)

M. BERTON, L. BENIMETSKAYA, E. ALLÉMANN, C.A. STEIN and R. GURNY
"Uptake of oligonucleotide-loaded nanoparticles in prostatic cancer cells and their  intracellular localization" 
European Journal of Pharmaceutics and Biopharmaceutics, 47, 119-123 (1999)

P. FURRER, J.M. MAYER, B. PLAZONNET and R. GURNY
"Ocular tolerance of preservatives on the murine cornea" 
European Journal of Pharmaceutics and Biopharmaceutics, 47, 105-112 (1999)

A. ROTHEN-WEINHOLD, K. BESSEGHIR, E. VUARIDEL, E.SUBLET, N. OUDRY and R. GURNY
"Stability studies of a somatostatin analogue in biodegradable implants" 
International Journal of Pharmaceutics, 178 (2), 213-221 (1999)

R.H. GUY, J.J. HOSTYNEK, R.S. HINZ and C.R. LORENCE
"Metals and the skin - Topical effects and percutaneous absorption" 
(Eds), Marcel Dekker, New York, p.431 (1999) 

A.L. STINCHCOMB, F. PIROT, G.D. TOURAILLE, A.L. BUNGE and R. H. GUY
"Chemical uptake into human stratum corneum in vivo from volatile and non-volatile solvents" 
Pharmaceutical Research, 16 (8), 1288-1293 (1999) 

V. MERINO, A. LOPEZ, D. HOCHSTRASSER and R. H. GUY
"Noninvasive sampling of phenylalanine by reverse iontophoresis" 
Journal of Controlled Release, 61 (1-2), 65-69 (1999)

V. MERINO, A. LOPEZ, Y. N. KALIA and R. H. GUY
"Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil" 
Pharmaceutical Research, 16 (5), 758-761 (1999)

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Synthesis and characterization of self-catalyzed  poly(ortho esters) based on decanediol and decanediol-lactate" 
J. Biomat. Sci. Polym. Ed. 10 (3), 375-389 (1999)

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Hydrolysis and erosion studies of autocatalyzed poly(ortho esters) containing lactoyl-lactyl acid dimers" 
Macromolecules 32 (2), 301-307 (1999)

N. VIVIEN CASTIONI, P.C. BAEHNI and R. GURNY
"Current status in oral fluoride pharmacokinetics and implications for the prophylaxis against dental caries" 
European Journal of Pharmaceutics and Biopharmaceutics, 45, 101-111 (1998)

B. GREWAL, A. NAIK, W. J. IRWIN and J. A. BOUWSTRA
"Transdermal iontophoresis of dextrans: donor concentration effects and enhancer pretreatment on steady state flux" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA,  pp. 24-25. (1998)

B. GREWAL, A. NAIK and W. J. IRWIN
"Drug, vehicle and enhancer interactions in percutaneous transport: simultaneous analysis by ATR-IR spectroscopy" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA,  pp. 569-570 (1998)

A. LUZARDO-ALVAREZ, J. BLANCO-MENDEZ, R. H. GUY and M.B. DELGADO-CHARRO
"Characterization of the permselective properties of neonatal porcine skin" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 601-602  (1998)

M.B. DELGADO-CHARRO, Y.N. KALIA and R.H. GUY
"The relative contributions of electrorepulsion and electroosmosis to iontophoretic transport" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 599-600 (1998)

N.M. RANJHA and  E. DOELKER
"Solute release behavior from pH-sensitive acrylic hydrogels for colonic drug delivery" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 886-887, Las Vegas (USA), 1998

D. QUINTANAR-GUERRERO, E. ALLÉMANN, E. DOELKER and H. FESSI
"A new procedure for the preparation of nanocapsules" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 842-843, Las Vegas (USA), 1998

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Understandig of degradation mechanism of autocatalyzed poly(ortho esters) containing lactoyl-lactic dimers" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 713-714, Las Vegas (USA) 1998

D. QUINTANR-GUERRERO, E. ALLEMANN, H. FESSI and E. DOELKER
"Pseudolatex preparation by direct displacement of partially water-miscible solvents from a conventional emulsion" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 840-841, Las Vegas (USA) 1998

E. DOELKER
"Release mechanisms of ingredients from controlled delivery systems" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 303, Las Vegas (USA) 1998

R.H. GUY, V. MERINO and A. LOPEZ
"Noninvasive sampling of phenylalanine by reverse iontophoresis" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 543-544 (1998)

A. LOPEZ, V. MERINO, Y.N. KALIA and R.H. GUY
"Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 597-598. (1998)

D. MARRO, Y.N. KALIA and R.H. GUY
"Effect of molecular structure on iontophoretic transport" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA,  pp. 77-78 (1998)

I. ALBERTI, Y.N. KALIA and R.H. GUY %20request
"Effect of percutaneous penetration enhancers on human skin barrier function in vivo
Proceed. 2nd World Meeting APGI/APV, Paris, pp. 853-854 (1998)

R.H. GUY, Y.N. KALIA, M.B. DELGADO-CHARRO, V. MERINO, A. LOPEZ and D. MARRO
"Iontophoresis: electrorepulsion and electroosmosis" 
Proceed. 5th European Symposium on Controlled Drug Delivery, Noordwijk aan Zee (The Netherlands),pp. 45-47 (1998)

F . J. OTERO-ESPINAR, M.B. DELGADO-CHARRO, S. ANGUIANO-IGEA and J. BLANCO-MENDEZ
"Using a tensile test to study the bioadhesive and swelling properties of polymers" 
in: Data Acquisition and Measurement techniques 
A. Muñoz-Ruiz and H. Vromans (eds.). Interpharm Press, Buffalo Grove,  pp. 295-342 (1998) 

M.B. DELGADO-CHARRO and R.H. GUY
"Iontophoresis of peptides" 
in: Electronically Controlled Drug Delivery; 
B. Berner and S. M. Dinh (eds.). CRC Press, Boca Raton, pp. 129-157 (1998) 

J.J. HOSTYNEK, R.S. HINZ, C.R. LORENCE and R.H. GUY
"Human skin penetration by metal compounds" 
in: Dermal Absorption and Toxicity Assessment, 
M.S. Roberts and K.A. Walters (eds), Marcel Dekker, New York, pp. 647-668 (1998) 

R.H. GUY
"Iontophoresis - Recent developments" 
J. Pharm. Pharmacol. 50, 371-374 (1998)

Y.N. KALIA, F. PIROT, R.O. POTTS and R.H. GUY
"Ion mobility in human stratum corneum in vivo
Journal of Pharmaceutical Sciences, 87, 1508-1511 (1998)

M.B. DELGADO-CHARRO and R.H. GUY
"Percutaneous penetration and transdermal drug delivery" 
Progr. Dermatol., 32(4), 1-12 (1998)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, E. DOELKER and H. FESSI
"Preparation and characterization of nanocapsules from preformed polymers by a new process based on emulsification-diffusion technique" 
Pharmaceutical Research, 15 (7), 1056-1062 (1998)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, H. FESSI and E. DOELKER
"Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers" 
Drug Dev.Ind.Pharm. 24 (12), 1113-1128 (1998)

F. DELIE
"Evaluation of nano- and microparticle uptake by the gastrointestinal tract" 
Adv.Drug Del.Rev. 34, 221-233 (1998)

F. DELIE and W. RUBAS
Préface 
Adv.Drug Delivery Rev. 34(2,3), 121 (1998)

Y.N. KALIA, L.B. NONATO, C.H. LUND and R.H.GUY
"Development of skin barrier function in premature infants" 
The Journal of Investigative Dermatology, 111, 320-326 (1998)

A. LUZARDO-ALVAREZ, M. RODRIGUEZ-FERNANDEZ, J. BLANCO-MENDEZ, R.H. GUY and M.B. DELGADO-CHARRO
"Iontophoretic permselectivity of mammalian skin: characterization of hairless mouse and porcine membrane models" 
Pharmaceutical Research, 15 (7), 984-987 (1998)

N.G. TURNER, C. CULLANDER and R.H. GUY
"Determination of the pH gradient across the stratum corneum" 
J. Invest. Dermatol. Symp. Proc. 3, 110-113 (1998)

J. BARRA, F. LESCURE, F. FALSON-RIEG and E. DOELKER
"Can the organization of a binary mix be predicted from the surface energy, cohesion parameter and particle size of its components?" 
Pharmaceutical Research, 15, 1727-1736 (1998)

M.B. SINTZEL, K. SCHWACH-ABDELLAOUI, K. MÄDER, R. STÖSSER, J. HELLER, C. TABATABAY and R. GURNY
"Influence of irradiation sterilization on a semi-solid poly(ortho ester)" 
International Journal of Pharmaceutics, 175, 165-176 (1998)

M.B. SINTZEL, J. HELLER, S.Y. Ng, C. TABATABAY, K. SCHWACH-ABDELLAOUI and R. GURNY
" In vitro drug release from self-catalysed poly(ortho ester): Case study of 5-fluorouracil" 
Journal of Controlled Release, 55, 213-218 (1998)

N.G. TURNER  and R. GUY
"Visualization and quantitation of iontophoretic pathways using confocal microscopy" 
J. Invest. Dermatol. Symp. Proc. 3,  136-142 (1998)

L. LANGKJAER, J. BRANGE, G.M. GRODSKY and R.H. GUY
"Iontophoresis of monomeric insulin analogues in vitro : effects of insulin charge and skin pretreatment" 
Journal of Controlled Release, 51, 47-56 (1998)

E. ALLÉMANN, J.-C. LEROUX and R. GURNY
"Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics" 
Adv. Drug Deliv. Rev. 34, 171-189 (1998)

O. FELT, P. BURI and R. GURNY
"Chitosan: A unique polysaccharide for drug delivery" 
Drug Dev. Ind. Pharm. 24 (11), 979-993 (1998)

P. BUSTAMANTE, M. ANGELES PEÑA and J. BARRA
"Partial-solubility parameters of piroxicam and niflumic acid" 
International Journal of Pharmaceutics, 174, 141-150 (1998)

A. GANEM-QUINTANAR, D. QUINTANAR-GUERRERO, F. FALSON-RIEG and P. BURI
" Ex vivo oral mucosal permeation of lidocaine hydrochloride with sucrose fatty acid esters as absorption enhancers" 
International Journal of Pharmaceutics, 173, 203-210 (1998)

P. BUSTAMANTE, M. ANGELES PEÑA and J. BARRA
"Partial-solubility parameters of naproxen and sodium diclofenac" 
J. Pharm. Pharmacol. 50, 975-982 (1998)

F. VEUILLEZ, A. GANEM-QUINTANAR, J. DESHUSSES, F. FALSON-RIEG and P. BURI
"Comparison of the ex-vivo oral mucosal permeation of tryptophan-leucine (Trp-Leu) and its myristoyl derivative" 
International Journal of Pharmaceutics, 170, 85-91 (1998)

A. GANEM-QUINTANAR, Y. JACQUES, F. FALSON-RIEG and P. BURI
"Lipid extracting effect of ethanol on keratinized oral mucosa" 
Pharmaceutical Research, 15 (3), 495-498 (1998)

Y.N. KALIA, V. MERINO and R.H. GUY
"Transdermal drug delivery: clinical aspects" 
Dermatol. Clin. 16, 289-299 (1998)

A.A. DESHPANDE, J. HELLER and R. GURNY
"Bioerodible polymers for ocular drug delivery" 
Crit. Rev. Ther. Drug Carrier Syst. 15 (4), 381-420 (1998)

C. WITSCHI and E. DOELKER
"Peptide degradation during preparation and in vitro release  testing of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) microparticles" 
International Journal of Pharmaceutics, 171, 1-18 (1998).

V. BAEYENS, V. KALTSATOS, B. BOISRAME, M. FATHI, and R. GURNY
"Evaluation of soluble bioadhesive ophthalmic drug inserts (BODI â ) for prolonged release of gentamicin: lachrymal pharmacokinetics and ocular tolerance" 
J. Ocular Pharm. 14 (3), 263-272 (1998).

J. BARRA and E. DOELKER
"Instrumentation of an eccentric tablet press" 
  in : Data Acquisition and Measurement Techniques, A.Muñoz-Ruiz and H. Vromans, (Ed), chap. 8, Interpharm Press, Inc., Buffalo Grove, Illinois, 1998, pp.189-238

N. ROUGE, E. ALLÉMANN, M. GEX-FABRY, L. BALANT, E.T. COLE, P. BURI and E. DOELKER
"Comparative pharmacokinetic study of a floating multiple-unit capsule, a high-density multiple-unit capsule and an immediate-release tablet containing 25 mg atenolol" 
Pharm. Acta Helv. 73, 81-87 (1998)

A.-L. CORNAZ-GUDET and P. BURI
"A simple and rapid high-performance liquid chromatography method to quantify and evaluate the purity of nicotine in solution and in microspheres" 
S.T.P. Pharma Sci. 8 (2), 139-144 (1998)

A. MERKLI, C. TABATABAY, R. GURNY and J. HELLER
"Biodegradable polymers for the controlled release of ocular drugs" 
Prog. Polym. Sci. 23, 563-580 (1998)

M.B. SINTZEL, J. HELLER, S.Y. Ng, M.S. TAYLOR, C. TABATABAY and R. GURNY
"Synthesis and characterization of self-catalyzed poly(ortho ester)" 
Biomaterials 19, 791-800 (1998)

N.M. RANJHA and E. DOELKER
"Equilibrium and dynamic swelling behaviour of pH-sensitive acrylic hydrogels for colonic drug delivery" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 937-938

F. VEUILLEZ, A. GANEM-QUINTANAR, J. DESHUSSES, F. FALSON-RIEG and P. BURI
"Comparison of the ex vivo buccal mucosa permeation of tryptophan-leucine (TRP-LEU) and its lipophilic derivative" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 923-924

Y. JACQUES, A. GANEM-QUINTANAR, E. TEILLAUD and P. BURI
"Permeability of heat-separated buccal epithelium to fentanyl in solution" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 921-922

I. ALBERTI, Y.N. KALIA and R.H. GUY
"Effect of percutaneous penetration enhancers on human skin barrier function in vivo" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 853-854

J. BARRA, F. FALSON-RIEG, F. LESCURE and E. DOELKER
"Effect of particle size on the interaction of powders in binary mixes, correlation with surface energy and cohesion parameters" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 133-134

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Synthesis and characterization of new bioerodible polymers designed for controlled drug release applications" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 275-276

A. ROTHEN-WEINHOLD, K. BESSEGHIR, E. VUARIDEL and R. GURNY
"Injection-moulding versus extrusion for the preparation of long-acting biodegradable implants" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 357-358

O. FELT, P. FURRER, J.M. MAYER, B. PLAZONNET, P. BURI and R. GURNY
"Topical use of chitosan in ophthalmology: tolerance assessment by confocal microscopy and precorneal retention evaluation by gamma scintigraphy" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 913-914

S. EINMAHL, M. ZIGNANI, V. BAEYENS, E. VARESIO, J.-L. VEUTHEY, J. HELLER, C. TABATABAY and R. GURNY
"A biodegradable polymer designed for concomitant delivery of dexamethasone and 5-fluorouracil to the eye" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 969-970

F. DE JAEGHERE, E. ALLÉMANN, F. KUBEL, B. GALLI, E. DOELKER and R. GURNY
"pH-sensitive microparticles as oral delivery systems for antiinfective agents of poor water solubility" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 559-560

V. BAEYENS, V. KALTSATOS, B. BOISRAMÉ, Ph. DRUET, J.-L. DAVOT and R. GURNY
"Clinical evaluation of bioadhesive ophthalmic drug inserts (Bodi) containing gentamicin for the treatment of external ophthalmic infection" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, 991-992

M. BERTON, E. ALLÉMANN, H. TÜRLER, R. WEIL, L. ZWILLENBERG and R. GURNY
"Poly(D,L-lactic acid) nanoparticles as phosphorothioate oligonucleotide carriers in U937 cells" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 1119-1120

E. ALLÉMANN , J.-C. LEROUX and R. GURNY
"Biodegradable nanoparticles of poly(lactic acid) and poly(lactic-co-glycolic acid) for parenteral administration"
in: Pharmaceutical Dosage Forms: Disperse Systems, vol. 3, H.A. Lieberman, M.M. Rieger and G.S. Banker (Ed.), Marcel Dekker, Inc., New York, Basel, Hong Kong, 1998, pp. 163-193

V. BAEYENS, V. KALTSATOS, B. BOISRAMÉ, E. VARESIO, J.-L. VEUTHEY, M. FATHI, L.P. BALANT, M. GEX-FABRY and R. GURNY
"Optimized release of dexamethasone and gentamicin from a soluble ocular insert for the treatment of external ophthalmic infections" 
Journal of Controlled Release, 52, 215-220 (1998)

A. ROTHEN-WEINHOLD, K. BESSEGHIR, Y. De ZELICOURT and R. GURNY
"Development and evaluation in vivo of a long-term delivery system for vapreotide, a somatostatin analogue" 
Journal of Controlled Release, 52, 205-213 (1998)

F. PIROT, E. BERARDESCA, Y.N. KALIA, M. SINGH, H.I. MAIBACH and R.H. GUY
"Stratum corneum thickness and apparent water diffusivity: facile and noninvasive quantitation in vivo
Pharmaceutical Research, 15 (3), 492-494 (1998)

C. WITSCHI and E. DOELKER
"Influence of the microencapsulation method and peptide loading on poly(lactic acid) and poly(lactic-co-glycolic acid) degradation during in vitro testing" 
Journal of Controlled Release, 51, 327-341 (1998)

M. ZIGNANI, S.F. BERNATCHEZ, T. Le MINH, C. TABATABAY,  J.M. ANDERSON and R. GURNY
"Subconjunctival biocompatibility of a viscous bioerodable poly(ortho ester)" 
J. Biomed. Mater Res. 39, 277-285 (1998)

D. QUINTANAR-GUERRERO, A. GANEM-QUINTANAR, E. ALLÉMANN, H. FESSI and E. DOELKER
"Influence of the stabilizer coating layer on the purification and freeze-drying of poly(D,L-lactic acid) nanoparticles prepared by an emulsion-diffusion technique" 
J. Microencapsul. 15(1), 107-119 (1998)

Y. JACQUES, T. NGUYEN-XUAN, E. IONESCU, G.P. RAVELLI, P. BURI, P. BAEHNI and R. GURNY
" In vivo evaluation of hydrophilic and hydrophobic mucoadhesive semi-solid formulations containing sucralfate and lidocaine for intraoral use" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 59-63 (1997)

V. BAEYENS, C. PERCICOT, M. ZIGNANI, A.A. DESHPANDE, V. KALTSATOS and R. GURNY
"Ocular drug delivery in veterinary medicine" 
Adv. Drug Del. Rev. 28, 335-361 (1997)

P. FURRER, J.M. MAYER and R. GURNY
"Confocal microscopy as a tool for the investigation of the anterior part of the eye" 
J. Ocular. Pharmacol. Ther. 13(6), 559-578 (1997)

E. ALLÉMANN, P. GRAVEL, J.-C. LEROUX, L. BALANT and R. GURNY
"Kinetics of blood component adsorption on poly(D,L-lactic acid) nanoparticles: evidence of complement C3 component involvement" 
J. Biomed. Mater Res. 37 (2), 229-234 (1997)

N. ROUGE, E.T. COLE, E. DOELKER and P. BURI
"Screening of potentially floating excipients for minitablets" 
S.T.P. Pharma Sci. 7, 386-392 (1997)

A. ROTHEN-WEINHOLD, K. BESSEGHIR and R. GURNY
"Analysis of the influence of polymer characteristics and core loading on the in vivo release of a somatostatin analogue" 
Eur. J. Pharm. Sci. 5, 303-313 (1997)

A.-F. RIME, D. MASSUELLE, F. KUBEL, H.-R. HAGEMANN and E. DOELKER
"Compressibility and compactibility of powdered polymers: poly(vinyl chloride) powders" 
European Journal of Pharmaceutics and Biopharmaceutics, 44, 315-322 (1997)

M.B. SINTZEL, S.Y. Ng, M.S. TAYLOR, J. HELLER, C. TABATABAY and R. GURNY
"Synthesis and characterization of ointment-like self-catalyzed poly(ortho ester)" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 909-910 (1997)

M. ZIGNANI, T. LE MINH, C. TABATABAY and R. GURNY
"Improved biocompatibility of a viscous bioerodable poly(ortho ester) by controlling the environmental pH" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 907-908 (1997)

N. VIVIEN-CASTIONI, R. GURNY, V. KALTSATOS and P. BAEHNI
"Prophylaxis of caries - in vivo evaluation of various oral fluoride containing preparations designed to optimize salivary concentrations" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 905-906 (1997)

F. DE JAEGHERE, E. ALLÉMANN, J.-C. LEROUX, W. STEVELS, P.J. DIJKSTRA, F. FEIJEN, E. DOELKER and R. GURNY
"PLA-PEG nanoparticles: preparation and cell interaction studies" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 831-832 (1997)

A. ROTHEN-WEINHOLD, K. BESSEGHIR and R. GURNY
"Development of a long-term delivery system for RC-160, a somatostatin analog" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 827-828 (1997)

M. BERTON, K. HOWARD, L. BENIMETSKAYA, E. ALLÉMANN, R. WEIL, L.O. ZWILLENBERG, C.A. STEIN and R. GURNY
"Uptake of oligonucleotide loaded nanoparticles in prostatic cancer cells and their intracellular localization" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 669-670 (1997)

V. BAEYENS, E. VARESIO, J.-L. VEUTHEY, V. KALTSATOS, B. BOISRAME, M. FATHI and R. GURNY
"Combined release of dexamethasone and gentamicin from an ocular insert for treatment of external ophthalmic infections" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 143-144 (1997)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, H. FESSI and E. DOELKER
"Applications of the ion-pair concept to hydrophilic substances with special emphasis on peptides" 
Pharmaceutical Research, 14 (2), 119-127 (1997)

A. GANEM-QUINTANAR, Y.N. KALIA, F. FALSON-RIEG and P. BURI
"Mechanisms of oral permeation enhancement" 
International Journal of Pharmaceutics, 156, 127-142 (1997)

Y. JACQUES, C. STAUB, I. MARQUET, C. CREBASSA and P. BURI
"Human buccal absorption of codeine phosphate from a bioadhesive drug delivery device" 
S.T.P. Pharma Sci. 7, 289-294 (1997)

Y. JACQUES and P. BURI
"An investigation of the physical behaviour of moisture-activated mucoadhesive hydrogels upon contact with biological and non-biological substrates" 
Pharm. Acta Helv. 72, 225-232 (1997)

V. BAEYENS and R. GURNY
"Chemical and physical parameters of tears relevant for the design of ocular drug delivery formulations" 
Pharm. Acta Helv. 72 191-202 (1997)

M.B. SINTZEL, A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Synthesis and analysis of viscous poly (ortho-ester) analogs for controlled drug release" 
International Journal of Pharmaceutics, 155, 263-269 (1997)

M. ZIGNANI, A. MERKLI, M.B. SINTZEL, S.F. BERNATCHEZ, W. KLOETI, J. HELLER, C. TABATABAY and R. GURNY
"New generation of poly(ortho esters): synthesis, characterization, kinetics, sterilization and biocompatibility" 
Journal of Controlled Release, 48, 115-129 (1997)

A.A. DESHPANDE, C. TABATABAY, P.M. HUGHES and R. GURNY
"Therapeutic applications of retinoids in ophthalmology" 
International Journal of Pharmaceutics, 157, 1-15 (1997)

M.B. SINTZEL, A. MERKLI, C. TABATABAY and R. GURNY
"Influence of irradiation sterilization on polymers used as drug carriers - A review" 
Drug Dev. Ind. Pharm. 23, 857-878 (1997)

R.M. BRAND, P. SINGH, E. ASPE-CARRANZA, H.I. MAIBACH and R.H. GUY
"Acute effects of iontophoresis on human skin in vivo : cutaneous blood flow and transepidermal water loss measurements" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 133-138 (1997)

N.G. TURNER, L. FERRY, M. PRICE, C. CULLANDER and R.H. GUY
"Iontophoresis of poly-L-lysines: the role of molecular weight?" 
Pharmaceutical Research, 14 (10), 1322-1331 (1997)

A. A. DESHPANDE, N. H. SHAH, C.T. RHODES and W. MALICK
"Development of a novel controlled-release system for gastric retention" 
Pharmaceutical Research, 14 (6), 815-819 (1997)

A. GANEM-QUINTANAR, F. FALSON-RIEG and P. BURI
"Contribution of lipid components to the permeability barrier of oral mucosa" 
European Journal of Pharmaceutics and Biopharmaceutics, 44, 107-120 (1997)

N.G. TURNER and R.H. GUY
"Iontophoretic transport pathways: dependence on penetrant physicochemical properties" 
J. Pharm. Sci., 86 (12), 1385-1389 (1997)

J. HIRVONEN and R.H. GUY
"Iontophoretic delivery across the skin: electroosmosis and its modulation by drug substances" 
Pharmaceutical Research, 14 (9), 1258-1263 (1997)

M.B. DELGADO-CHARRO, G. IGLESIAS-VILAS, J. BLANCO-MENDEZ, A. LOPEZ.QUINTELA, J.P. MARTY and R.H. GUY
"Delivery of a hydrophilic solute through the skin from novel microemulsion systems" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 37-42 (1997)

E. ALLÉMANN, N. BRASSEUR, S.V. KUDREVICH, C. LA MADELEINE and J.E. VAN LIER
"Photodynamic activities and biodistribution of fluorinated zinc phthalocyanine derivatives in the murine EMT-6 tumour model" 
Int. J. Cancer 72, 289-294 (1997)

A.-L. CORNAZ-GUDET, A.F. GANEM QUINTANAR, and P. BURI
"Simple method of in vitro diffusion of nicotine across porcine palatine mucosa" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 259-264 (1997)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, E. DOELKER and H. FESSI
"A mechanistic study of the formation of pollymer nanoparticles by the emulsification-diffusion technique" 
Colloid Polym. Sci. 275, 640-647 (1997)

V. MERINO, I. ALBERTI, Y.N. KALIA and R.H. GUY
"Transdermal and skin-targeted drug delivery" 
Journal of Cutaneous Medicine and Surgery, 2(2), 108-119 (1997)

V. MERINO, Y.N. KALIA and R.H. GUY
"Transdermal therapy and diagnosis by iontophoresis" 
Trends Biotechnol., 15, 288-290 (1997)

C. WITSCHI and E. DOELKER
"Residual solvents in pharmaceutical products: acceptable limits, influences on physicochemical properties, analytical methods and documented values" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 215-242 (1997)

J. BARRA, F. LESCURE, E. DOELKER and P. BUSTAMANTE
"The expanded Hansen approach to solubility parameters. Paracetamol and citric acid in individual solvents" 
J. Pharm. Pharmacol. 49, 644-651 (1997)

V. BAEYENS, E. VARESIO, J.-L. VEUTHEY and R. GURNY
"Determination of dexamethasone in tears by capillary electrophoresis" 
J. Chromatogr. B. 692, 222-226 (1997)

N.G. TURNER, Y.N. KALIA and R.H. GUY
"The effect of current on skin barrier function in vivo : recovery kinetics post-iontophoresis" 
Pharmaceutical Research, 14 (9), 1252-1257 (1997)

F. PIROT. Y.N. KALIA, A.L. STINCHCOMB, G. KEATING, A. BUNGE and R.H. GUY
"Characterization of the permeability barrier of human skin in vivo
Proceed. Natl. Acad. Sci. USA, 94, 1562-1567 (1997)

A. ROTHEN-WEINHOLD and R. GURNY
"Controlled and/or prolonged parenteral delivery of peptides from the hypothalamic pituitary axis" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 115-131 (1997)

J. BARRA, F. KUBEL and  E. DOELKER
"Polymorphism of paracetamol. New advances" 
Proceed. 3rd Symposium/workshops on pharmacy and thermal analysis, Switzerland, 2PO, 1997

Y.N. KALIA and R.H.GUY
"Interaction between penetration enhancers and iontophoresis: effect on human skin impedance in vivo
Journal of Controlled Release, 44, 33-42 (1997)

N. ROUGE, J.-C. LEROUX, E.T. COLE, E. DOELKER and P. BURI
"Prevention of the sticking tendency of floating minitablets filled into hard gelatin capsules" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 165-171 (1997)

A. GANEM-QUINTANAR, C. LAFFORGUE, F. FALSON-RIEG, P. BURI
"Evaluation of the transepidermal permeation of diethylene glycol monoethyl ether and skin water loss" 
International Journal of Pharmaceutics, 147, 165-171 (1997)

J. BARRA and R. SOMMA
"Influence of the physicochemical variability of magnesium stearate on its lubricant properties: possible solutions" 
Drug Dev. Ind. Pharm. 22, 1105-1120  (1996)

J. BARRA, F. LESCURE and E. DOELKER
"Influence of surface free energies and cohesion parameters on pharmaceutical  material interaction parameters - Theoretical simulations" 
Pharmaceutical Research, 13 (11), 1746-1751 (1996)

F. GURTLER, V. KALSATOS, B. BOISRAME and R. GURNY
"Development of a novel soluble ophthalmic insert: evaluation of ocular tolerance in rabbits" 
European Journal of Pharmaceutics and Biopharmaceutics, 42 (6), 393-398 (1996)

M.B. SINTZEL, S.F. BERNATCHEZ, C. TABATABAY and R. GURNY
"Biomaterials in ophthalmic drug delivery" 
European Journal of Pharmaceutics and Biopharmaceutics, 42, 358-374 (1996)

G. MESEGUER, P. BURI, B. PLAZONNET, A. ROZIER and R. GURNY
"Gamma scintigraphic comparison of eyedrops containing pilocarpine in healthy volunteers" 
J. Ocul. Pharmacol. Ther. 12, 481-488 (1996)

D. QUINTANAR-GUERRERO, H. FESSI, E. ALLÉMANN and E. DOELKER
"Influence of stabilizing agents and preparative variables on the formation of poly(D,L-lactic acid) nanoparticles by an emulsification-diffusion technique" 
International Journal of Pharmaceutics, 143, 133-141 (1996)

J.-C. LEROUX, E. ALLÉMANN, F. DE JAEGHERE, E. DOELKER and R. GURNY
"Biodegradable nanoparticles - From sustained release formulations to improved site specific drug delivery" 
Journal of Controlled Release, 39, 339-350 (1996)

N. ROUGE, P. BURI and E. DOELKER
"Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery" 
International Journal of Pharmaceutics, 136, 117-139 (1996)

E. ALLÉMANN, J. ROUSSEAU, N. BRASSEUR, S.V. KUDREVICH, K. LEWIS and J.E. VAN LIER
"Photodynamic therapy of tumours with hexadecafluoro zinc phthalocyanine formulated in PEG-coated poly(lactic acid) nanoparticles" 
Int. J. Cancer 66, 821-824 (1996)

J.-C. LEROUX, E. DOELKER and R. GURNY
"The use of drug load nanoparticles in cancer chemotherapy" 
  in : MICROENCAPSULATION - Methods and industrial application, S. Benita, éd., Marcel Dekker, Inc., New York, Basel, Hong Kong, Chap. 16, 1996, pp. 535-575

V.H.L. LEE, H. YAMAHARA, R. GURNY, M.B. SINTZEL, M. MARTENET, M. GEX-FABRY, L. BALANT, S. OHDO and S.K. PODDER
"Basis for dosing time-dependent changes in the ocular and systemic absorption of topically applied timolol" 
J. Ocular Pharmacol. Ther. 12 (2), 103-113 (1996)

T. NGUYEN-XUAN, R. TOWART, A. TERRAS, Y. JACQUES, P. BURI and R. GURNY
"Mucoadhesive semi-solid formulations for intraoral use containing sucralfate" 
European Journal of Pharmaceutics and Biopharmaceutics, 42 (2), 133-137 (1996)

J. KRISTL, E. ALLÉMANN and R. GURNY
"Formulation and evaluation of zinc-phthalocyanine loaded poly(D,L-lactic acid) nanoparticles" 
Acta Pharm. 46, 1-12 (1996)

C. BITZ and E. DOELKER
"Influence of the preparation method on residual solvents in biodegradable microspheres" 
International Journal of Pharmaceutics, 131, 171-181 (1996)

A.-L. CORNAZ, A. DE ASCENTIS, P. COLOMBO and P. BURI
" In vitro characteristics of nicotine microspheres for transnasal delivery" 
International Journal of Pharmaceutics, 129, 175-183 (1996)

J. HIRVONEN, Y.N. KALIA and R.H. GUY
"Transdermal delivery of peptides by iontophoresis" 
Nature Biotechnology, 14, 1710-1713 (1996)

Y.N. KALIA, F. PIROT and R.H. GUY
"Homogeneous transport in a heterogeneous membrane: water diffusion across human stratum corneum in vivo
Biophysical Journal, 71, 2692-2700 (1996)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Purity and stability assessment of a semi-solid poly(ortho ester) used in drug delivery systems" 
Biomaterials 17, 897-902 (1996)

R.H. GUY, Y.N. KALIA, C.S. LIM, L.B. NONATO and N.G. TURNER
"Drug smuggling - creative ways to cross biological barriers" 
Chemistry in Britain. 32, 42-45 (1996)

Y.N. KALIA, L.B. NONATO and R.H. GUY
"The effect of iontophoresis on skin barrier integrity: Non-invasive evaluation by impedance spectroscopy and transepidermal water loss" 
Pharmaceutical Research, 13 (6), 957-961 (1996)

J.-C. LEROUX, R.M. COZENS, J.L. ROESEL, B. GALLI, E. DOELKER and R. GURNY
"pH-sensitive nanoparticles: an effective means to improve the oral delivery of HIV-1 protease inhibitors in dogs" 
Pharmaceutical Research, 13, 485-487 (1996)

A.-C. VIAL-BERNASCONI, P. BURI, E. DOELKER, E. BEYSSAC, G. DUCHAIX and J.-M. AIACHE
" In vivo evaluation of an indomethacin monolithic, extended zero-order release hard-gelatin capsule formulation based on saturated polyglycolysed glycerides" 
Pharm. Acta Helv. 70, 307-313 (1995)

N. FOLLONIER, E. DOELKER and E.T. COLE
"Various ways of modulating the release of diltiazem hydrochloride from hot-melt extruded sustained release pellets prepared using polymeric materials" 
Journal of Controlled Release, 36, 243-250 (1995)

A. MERKLI, C. TABATABAY and R. GURNY
"Use of insoluble biodegradable polymers in ophthalmic systems for the sustained release of drugs" 
European Journal of Pharmaceutics and Biopharmaceutics, 41, 271-283 (1995)

J.-C. LEROUX, R. COZENS, J.L. ROESEL, B. GALLI, F. KUBEL, E. DOELKER and R. GURNY
"Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice" 
Journal of Pharmaceutical Sciences, 84 (12), 1387-1391 (1995)

F. GURTLER, V. KALTSATOS, B. BOISRAME, J. DELEFORGE, M. GEX-FABRY, L.P. BALANT and R. GURNY
"Ocular availability of Gentamicin in small animals after topical administration of a conventional eye drop solution and a novel long acting bioadhesive ophthalmic drug insert" 
Pharmaceutical Research, 12, 1791-1795 (1995)

M. ZIGNANI, C. TABATABAY and R. GURNY
"Topical semi-solid drug delivery: kinetics and tolerance of ophthalmic hydrogels" 
Adv. Drug Delivery Rev. 16, 51-60 (1995)

J.-C. LEROUX, F. DE JAEGHERE, B. ANNER, E. DOELKER and R. GURNY
"An investigation on the role of plasma and serum opsonins on the internalization of  biodegradable poly(D,L-lactic acid) nanoparticles by human monocytes" 
Life Sciences 57 (7), 695-703 (1995)

E. ALLÉMANN, N.BRASSEUR, O. BENREZZAK, J. ROUSSEAU, S.V. KUDREVICH, R.W. BOYLE, J.-C. LEROUX, R. GURNY and J.E. VAN LIER
"PEG-coated poly(lactic acid) nanoparticles for the delivery of hexadecafluoro zinc  phthalocyanine to EMT-6 mouse mammary tumours" 
J. Pharm. Pharmacol. 47, 382-387 (1995)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"The use of acidic and basic excipients in the release of 5-fluorouracil and mitomycin  C from a semi-solid bioerodible poly(ortho ester)" 
Journal of Controlled Release, 33, 415-421 (1995)

F. GURTLER, R. GURNY, V. KALTSATOS and B. BOISRAME
"Keeping the drug in your eye" 
CHEMTECH 25 (4), 33-34 (1995)

F. GURTLER, V. KALTSATOS, B. BOISRAME and R. GURNY
"Long-acting soluble Bioadhesive Ophthalmic Drug Insert (BODI) containing  gentamicin for veterinary use : optimization and clinical investigation" 
Journal of Controlled Release, 33, 231-236 (1995)

E. DOELKER, D. MASSUELLE, F. VEUILLEZ and P. HUMBERT-DROZ
"Morphological, packing, flow and tableting properties of new Avicel types" 
Drug Dev. Ind. Pharm. 21 (6), 643-661 (1995)

J.-C. LEROUX, E. ALLÉMANN, E. DOELKER and R. GURNY
"New approach for the preparation of nanoparticles by an emulsification-diffusion  method" 
European Journal of Pharmaceutics and Biopharmaceutics, 41, 14-18 (1995)

C. TABATABAY, S.F. BERNATCHEZ and R. GURNY
"Proceed with caution whenever using commercial 5-fluorouracil solution in glaucoma filtration surgery" 
Ocular Surgery News, International Edition, 5, 19 (1994)

E. DOELKER
"Assessment of powder compaction" 
in : Powder Technology and Pharmaceutical Processes, éd. D. Chulia, M. Deleuil and Y.Pourcelot, Elsevier, Amsterdam, chap. 13, 1994, pp 403-471

F. GURTLER and R. GURNY
"Patent literature review of ophthalmic inserts" 
Drug Dev. Ind. Pharm. 21 (1), 1-18 (1995)

M.B. DELGADO-CHARRO and R.H. GUY
"Characterization of convective solvent flow during iontophoresis" 
Pharmaceutical Research, 11 (7), 929-935 (1994)

F. LESCURE, R. GURNY and E. DOELKER
" In vitro and in vivo evaluation of progesterone implants based on new biodegradable  poly(glutamic and glutamate esters) copolymers" 
J. Biomater. Sci. Polymer Edn, 6, 797-807 (1994)

R. GURNY, S.F. BERNATCHEZ, A. MERKLI and C. TABATABAY
"New semi solid poly(ortho esters) designed for controlled drug delivery of injectable  products" 
B.T. Gattefossé 87, 63-66 (1994)

A.-L. CORNAZ and P. BURI
"Nasal mucosa as an absorption barrier" 
European Journal of Pharmaceutics and Biopharmaceutics, 40 (5), 261-270 (1994)

L.P. BALANT and E. DOELKER
"Metabilic considerations in prodrug design" 
in : Burger's Medical Chemistry and Drug Discovery, Fifth Edition, Vol. 1 : Principles and Practice, chapter 23, éd. M.E. Wolf, 1995, John Wiley & Sons, Inc.

G. MESEGUER, R. GURNY and P. BURI
" In vivo evaluation of dosage forms : application of gamma scintigraphy to non- enteral routes of administration" 
J. Drug Target. 2, 269-288 (1994)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Gamma sterilization of a semi-solid poly(ortho ester) designed for controlled drug  delivery - Validation and radiation effects" 
Pharmaceutical Research, 11, 1485-1491 (1994)

S. AFTABROUSHAD and E. DOELKER
"Factors influencing the entrapment of a water soluble model drug into injectable  microparticles prepared using solvent evaporation and phase separation techniques"
European Journal of Pharmaceutics and Biopharmaceutics, 40, 237-242 (1994)

N. VIVIEN, P. BURI, L. BALANT and S. LACROIX
"Nasal absorption of metoclopramide administered to man" 
European Journal of Pharmaceutics and Biopharmaceutics, 40, 228-231 (1994)

S. BERNATCHEZ, A. MERKLI, T. LE MINH, C. TABATABAY, J. ANDERSON and R. GURNY
"Biocompatibility of a new semisolid bioerodible poly(ortho ester) intended for the  ocular delivery of 5-fluorouracil" 
J. Biomed. Mat. Res., 28, 1037-1046 (1994)

G. MESEGUER, P. BURI and R. GURNY
"Application of medical imaging to pharmaceutical research : The example of gamma  scintigraphy. I. Technological aspects" 
European Journal of Pharmaceutics and Biopharmaceutics, 40, 111-121 (1994)

N. FOLLONIER, E. DOELKER and E.T. COLE
"Evaluation of hot-melt extrusion as a new technique for the production of polymer-based pellets for sustained release capsules containing high loadings of freely soluble  drugs" 
Drug Dev. Ind. Pharm. 20, 1323-1339 (1994)

S.F. BERNATCHEZ, C. TABATABAY and R. GURNY
"Sodium hyaluronate as a vehicle for an improved tolerance of 5-fluorouracil  administered subconjunctivally to rabbits" 
International Journal of Pharmaceutics, 106, 161-166 (1994)

J.-C. LEROUX, P. GRAVEL, L. BALANT, B. VOLET, B.M. ANNER, E. ALLÉMANN, E. DOELKER and R. GURNY
"Internalization of poly (D,L-lactic acid) nanoparticles by isolated human leukocytes  and analysis of plasma proteins adsorbed onto the particles" 
J. Biomed. Mat. Res., 28, 471-481 (1994)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Semi-solid hydrophobic bioerodible poly(ortho ester) for potential application in  glaucoma filtering surgery" 
Journal of Controlled Release, 29, 105-112 (1994)

E. ALLÉMANN , R. GURNY, E. DOELKER, F.S. SKINNER and H. SCHÜTZ
"Distribution, kinetics and elimination of radioactivitiy after intravenous and  intromuscular injection of 14C-savoxepine loaded poly (D,L-lactic acid) nanospheres  to rats" 
Journal of Controlled Release, 29, 97-104 (1994)

E. DOELKER, G. MESEGUER, A.-L. CORNAZ, H. LEUENBERGER, S. STRAUSAK and E. MELIK
"Pommade au stéarate" - Nouvelle formule, sans triéthanolamine" 
J.S.Ph. 132, 59-62 (1994)

E. ALLÉMANN, J.-C. LEROUX, R. GURNY and E. DOELKER
" In vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles  produced by  salting-out procedure" 
Pharmaceutical Research, 10, 1732-1737 (1993)

E. DOELKER
"Comparative compaction properties of various microcrystalline cellulose types and  generic products" 
Drug Dev. Ind. Pharm. 19, 2399-2471 (1993)

N. FOLLONIER and E. DOELKER
"Accelerated ageing test for predicting the short-term change of the mechanical  strength of compressed tablets" 
European Journal of Pharmaceutics and Biopharmaceutics, 39 (6), 267-268 (1993)

E. ALLÉMANN, R. GURNY, E. DOELKER
"Drug-loaded nanoparticles - Preparation methods and drug targeting issues" 
European Journal of Pharmaceutics and Biopharmaceutics, 39 (5), 173-191 (1993)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Synthesis and characterization of a new biodegradable semi-solid poly(ortho  ester) for drug delivery systems" 
J. Biomater. Sci. Polymer Edn, 4, 505-516 (1993)

G. MESEGUER, R. GURNY, P. BURI, A. ROZIER and B. PLAZONNET
"Gamma scintigraphic study of precorneal drainage and assessment of miotic response in rabbits of various ophthalmic formulations containing pilocarpine" 
International Journal of Pharmaceutics, 95, 229-234 (1993)

S.F. BERNATCHEZ, A. MERKLI, C. TABATABAY, R. GURNY, Q.H. ZHAO, J.M. ANDERSON and J. HELLER
  "Biotolerance of a semisolid hydrophobic biodegradable poly(ortho ester) for  controlled drug delivery" 
J. Biomed. Mat. Res. 27, 677-681 (1993)

A.-F. RIME and E. DOELKER
"Caractéristiques de compression et comprimabilité des poudres de polymères à  usage pharmaceutique" 
S.T.P. Pharma Sciences 3 (2), 109-129 (1993)

E. DOELKER
"Cellulose Derivatives" 
in:  Advances in Polymer Sciences, Springer-Verlag, Berlin - Heidelberg, Vol. 107,  1993, pp 199-265

E. ALLÉMANN , E. DOELKER and R. GURNY
"Drug loaded poly(lactic acid) nanoparticles produced by a reversible salting-out  process : Purification of an injectable dosage form" 
European Journal of Pharmaceutics and Biopharmaceutics, 39, 13-18 (1993)

R. GURNY, C. TABATABAY, S.F. BERNATCHEZ, A. MERKLI, E. ALLÉMANN, C. AFTABROUCHAD, F. LESCURE and E. DOELKER
"Biodegradable polymers - Contemporary issues and new directions" 
Eur. J. Hosp. Pharm., 3, 15-19 (1993)

S.F. BERNATCHEZ, C. TABATABAY and R. GURNY
"Sodium hyaluronate 0.25% used as a vehicle increases the bioavailability of  topically administered gentamicin" 
Graefe's Arch. Clin. Exp. Ophthalmol. 231, 157-171 (1993)

Y. JACQUES and P. BURI
"Optimization of an ex vivo method for bioadhesion quantification" 
European Journal of Pharmaceutics and Biopharmaceutics, 38, 195-198 (1992)

S.F. BERNATCHEZ, O. CAMBER, C. TABATABAY and R. GURNY
"Use of hyaluronic acid in ocular therapy" 
in : Biopharmaceutics of Ocular Drug Delivery, P. Edman, ed., CRC Press, Boca Raton, Florida, Chap. 7 1993,pp 105-120

R. GURNY, H. IBRAHIM and P. BURI
"The development and use of in situ formed gels, triggered by pH" 
in : Biopharmaceutics of Ocular Drug Delivery, P. Edman, ed., CRC Press, Boca Raton, Florida, Chap. 5, 1993, pp 81-90

E. ALLÉMANN, R. GURNY and E. DOELKER
"Preparation of aqueous polymeric nanodispersions by a reversible salting-out  process : influence of process parameters on particle size" 
International Journal of Pharmaceutics, 87, 247-253 (1992)

H. IBRAHIM, C. BINDSCHAEDLER, E. DOELKER, P. BURI and R. GURNY
"Aqueous nanodispersions prepared by a salting out process" 
International Journal of Pharmaceutics, 87, 239-246 (1992)

F. LESCURE, R. GURNY, E. DOELKER and J.M. ANDERSON
"Long-term histopathological study of new polypeptidic biomaterials" 
Biomaterials 13 (14), 1009-1011 (1992)

C. AFTABROUCHAD and E. DOELKER
"Méthodes de préparation des microparticules biodégradables chargées en principes   actifs hydrosolubles" 
S.T.P. Pharma Sciences 2, 365-380 (1992)

Y. JACQUES and P. BURI
"Etude cinétique de l'hydratation de comprimes mucoadhesifs par mesure de la force de gonflement" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. Ill, 286-295, Paris (1992) 

C. AFTABROUCHAD and E. DOELKER
"Microparticules biodegradables chargées en principes actifs hydrosolubles : comparaison des méthodes de la séparation de phases et de l'évaporation du solvant" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. II, 213-222, Paris (1992)

N. FOLLONIER, E. DOELKER and E.T. COLE
"Optimization of the release of a highly dosed freely soluble drug from hot-melt extruded sustained release pellets prepared using polymeric materials" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. IV, 100-109, Paris (1992)

G. MESEGUER, R. GURNY, P. BURI, A. ROZIER and B. PLAZONNET
"Precorneal drainage of various pilocarpine-containing formulations assessed by gamma scintigraphy and comparison of residence time with prolongation of miotic response in rabbits" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. IV, 35-42, Paris (1992)

E. ALLEMANN, R. GURNY and E. DOELKER
"Preparation and optimization of nanoparticles by a reversible salting-out process avoiding surfactants" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. Ill, 15-21, Paris (1992)

L. P. BALANT, A.E. BALANT-GORGIA, M. GEX-FABRY and M. EICHELBAUM
"Genetic polymorphisms in human drug metabolism" 
in: New Trends in Pharmacokinetics, A. Rescigno and A.K. Thakur, eds. Plenum Press, New York, 391 (1991)

N. FOLLONIER and E. DOELKER
"Biopharmaceutical comparison of oral multiple-unit and single-unit sustained-release dosage forms" 
S.T.P. Pharma Sciences 2, 141-158 (1992)

S. KOPP-KUBEL, C. BEYER,  E. GRAF, F. KUBEL and E. DOELKER
"Einfluss der Polymorphie von Phenobarbital auf Tabletteneigenschaften" 
European Journal of Pharmaceutics and Biopharmaceutics, 38, 17-25 (1992)

M.-P. DANDELOT KELLER, P. BURI and E. CHAROLLAIS
"Importance des lipases du tractus digestif pour l'hydrolyse des excipients lipidiques et l'enzymotherapie de substitution" 
- Deuxième partie Pharm. Acta Helv. 67, 66-68 (1992)

M.-P. DANDELOT KELLER, P. BURI and E. CHAROLLAIS
"Importance des lipases du tractus digestif pour l'hydrolyse des excipients lipidiques et l'enzymothérapie de substitution" 
- Première partie Pharm. Acta Helv. 67, 34-42 (1992)

L. P. BALANT, E. DOELKER and P. BURI
"Pharmacokinetic Strategies in the Development of Prodrugs" 
in: New Trends in Pharmacokinetics, A. Rescigno and A.K. Thakur, eds. Plenum Press, New York, 281 (1991)

H. IBRAHIM, C. BINDSCHAEDLER, E. DOELKER, P. BURI and R. GURNY
"Concept and development of ophthalmic pseudo-latexes triggered by pH"
Int. J. Pharm. 77, 211-219(1991)

E. DOELKER
"Nécessité de nouvelles voies et formes d 'administration pour les médicaments de nature peptidique - Innover pour réussir" 
J.S.Ph. 18, 490-495 (1991)

V. BELTRAMI, R. GURNY and E. DOELKER
"Comparative swelling behavior of crosslinked vinyl alcohol homo- and copolymers" 
18th Intern. Symp. Control. Rel. Bioact. Mater., Amsterdam (1991)

B. GANDER, F. KLOETI and P. CHRISTEN
"Stability of corticosteroids in zinc oxide- hydrophilic paste and lipophilic ointment" 
Eur. J. Pharm. Biopharm. 37, 64-68 (1991)

E. DOELKER
"Swelling behavior of water-soluble cellulose derivatives" 
in: Absorbent Polymer Technology (Studies in Polymer Science 8), eds;L. Brannon-Peppas and R.S. Harland, 125-145 , Elsevier, Amsterdam (1990)

A.-F. RIME, F. LESCURE, D. MORDIER, R. GURNY and E. DOELKER
"A new high performance data acquisition system interfacing an instrumented tablet machine to a microcomputer" 
Acta Pharm. Technol. 36, 264-268 (1990)

P. CHRISTEN, F. KLOETI and B. GANDER
Research and Reports "Stability of prednisolone and prednisolone acetate in various vehicles used in semi-solid topical preparations" 
J. Clin. Pharm. Thera.  15, 325-329  (1990)

R. GURNY, J. E. RYSER, C. TABATABAY, M. MARTENET, P. EDMAN and O. CAMBER
"Precorneal residence time in humans of sodium hyaluronate as measured by gamma scintigraphy" 
Graefe's Arch. Clin. Exp. Ophthalmol. 228, 510-512 (1990)

J. VONDERSCHER, P. BURI, J. DESHUSSES and H. SUCKER
"Absorption rate of drugs in rats - Application of the improved modified doluisio method to various classes of drugs" 
Acta Pharm. Technol. 36, 133-138 (1990)

L. P. BALANT, E. DOELKER and P. BURI
"Prodrugs for the improvement of drug absorption via different routes of administration" 
Eur. J. Drug Metab. Pharmacokinet. 15, 143-153 (1990)

V. BELTRAMI, R. GURNY and E. DOELKER
"Le poly(alcool) de vinyle dans les formes à libération prolongée destinées à la voie orale" 
Revue - Pharm. Acta Helv. 65, 130-142 (1990)

H. IBRAHIM, R. GURNY, P. BURI, J. GROVE, A. ROZIER and B. PLAZONNET
"Ocular bioavailability of pilocarpine from a phase transition latex system triggered by pH" 
Communication : 4e Congrès Européen de Biopharmacie et de Pharmacocinétique, Genève  (1990)

F. LESCURE, R. GURNY, E. DOELKER and D. BICHON
"Effect of various factors on the in vitro release of progesterone from a new class of implantable polypeptide" 
Communication : 4e Congrès Européen de Biopharmacie et de Pharmacocinétique, Genève (1990)

K.V. RANGA RAO, K. PADMALATHA DEVI and P. BURI
"Influence of molecular size and water solubility of the solute on its release from swelling and erosion controlled polymeric matrices" 
J. Control. Release, 12, 133-141 (1990)

S. KOPP-KUBEL, C. BEYER, E. GRAF and E. DOELKER
"Studien des Bruchverhaltens von Tabletten am Beispiel einer isotropen und einer anisotropen Model substanz" 
Acta Pharm. Technol. 36, 24-29 (1990)

P. WUTHRICH and P. BURI
"Intérêt de la voie transnasale pour l'administration des médicaments" 
Deuxième partie: "Modèles d 'étude de l'absorption nasale chez l'animal et paramètres susceptibles de l'influencer" 
Pharm. Acta Helv. 65, 2-13 (1990)

P. WUTHRICH and P. BURI  
"Intérêt de la voie transnasale pour l'administration des médicaments" 
Première partie:  "Aspects de l'anatomie et de la physiologie nasale" 
Pharm. Acta Helv. 64, 322-331 (1989)

B. GANDER, V. BELTRAMI, R. GURNY and E. DOELKER
"Effects of the method of drug incorporation and the size of the monolith on drug release from cross-linked polymers" 
Int. J. Pharm. 58, 63-71 (1990)

E. DOELKER, D. MORDIER and S. KOPP
"Relevance of various mechanical strength measurements of pharmaceutical compressed tablets" 
in:  Powders and Grains - Proceedings of the International Conference on Micromechanics of Granular Media, J.Biarez and R. Gourves, eds, A.A. Balkema, Rotterdam, 411-416 (1989) 

F. LESCURE, R. GURNY, E. DOELKER, M. L. PELAPRAT, D. BICHON and J.M. ANDERSON
"Acute histopathological response to a new biodegradable polypeptidic polymer for implantable drug delivery system" 
J. Biomed. Mater. Res. 23, 1299-1313  (1989)

K.V. RANGA RAO and P. BURI
"A novel laboratory model for the film coating of microparticles" 
Acta Pharm. Technol. 35, 256-257 (1989)

B. GANDER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Effect of polymeric network structure on drug release from cross-linked poly(vinyl alcohol) micromatrices" 
Pharmaceutical Research 6, 578-584 (1989)

F. LESCURE, R. GURNY, E. DOELKER and J. AUGUSTYNSKI
"Utilisation du principe de l'iontophorèse ou de l'électrophorèse pour le contrôle de la libération de substances médicamenteuses " 
Pharm. Acta Helv. 64, 210-219 (1989)

K.V. RANGA RAO and P. BURI
"A novel in situ method to test polymers and coated microparticles for bioadhesion" 
Int. J. Pharm. 52, 265-270  (1989)

R. DIEPOLD, J. KREUTER, J. HIMBER, R. GURNY, V.H.L. LEE, J.R. ROBINSON, M.F. SAETTONE and O.E. SCHNAUDIGL
"Comparison of different models for the testing of pilocarpine eyedrops using conventional eyedrops and a novel depot formulation (nanoparticles)" 
Graefe's Arch. Clin. Exp. Ophthalmol. 227, 188-193 (1989)

K.V. RANGA RAO, K. PADMALATHA DEVI and P. BURI
"Zero-order release of a very soluble drug from swelling and erosion controlled polymeric matrices" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. V, 242-249 (1989)

V. BELTRAMI, R. GURNY and E. DOELKER
"Matrices de poly(alcool de vinyle) à libération contrôlée, influence de l'inactivation de l'agent de réticulation sur les caractéristiques de gonflement, de chargement en principes actifs, et sur les profils de libération" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. V, 205-214 (1989) 

A.-F. RIME, F. LESCURE, D. MORDIER, R. GURNY and E. DOELKER
"Nouveau système d 'acquisition de données pour machine à comprimer instrumentée développée sur micro-ordinateur" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. IV, 425-432 (1989) 

M. P. DANDELOT KELLER, P. BURI and E. CHAROLLAIS
"Importance de la lipase gastrique sur la vitesse de libération in vitro d'une substance incorporée dans un excipient lipidique" 
Compte rendu 5e Congrès International de technologie pharmaceutique, APGI, Paris, Vol. IV, 126-133 (1989)

A. BEN-AMOR, E. DOELKER and P. BURI
"Augmentation de la biodisponibilité d'un agent hypolipémiant par incorporation dans une gélule à contenu liquide" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. Ill, 190-199 (1989)

C. KOLLER and P. BURI
"Libération in vitro de phenylephrine à partir de gels thermoreversibles" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. II, 112-121 (1989)

B. GANDER, R. GURNY and E. DOELKER
"Structural analysis of poly(vinyl alcohol) cross-linked by gamma irradiation in the presence of cosolutes, possibilities and limitations in formulation" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 261-267 (1989) 

B. GANDER and N. B. GRAHAM
"Monolayer adsoprtion of surfactants on drug crystals and its potential for modifying powder properties" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 251-260 (1989) 

E. DOELKER, D. MORDIER and F. KUBEL
"Possibilités d'erreur d 'interprétation des diagrammes d'analyse thermique des substances polymorphes, exemple du sulfabenzamide" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 222-231 (1989)

P. WUTHRICH, M. MARTENET and P. BURI
"Etude de la biodisponibilité du tetracosactide (AGTH1,24) après administration intranasale chez le rat" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 84-90 (1989)

H. IBRAHIM, R. GURNY, C. BINDSCHAEDLER and P. BURI
"Nouvelle technologie pour la préparation de systèmes médicamenteux microparticulaires à usage ophtalmique" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 70-76 (1989)

K .V. RANGA RAO, A. BEN-AMOR and P. BURI
"Studies on buccoadhesive tablet formulation of codeine phosphate" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 15-21 (1989)

S. KOPP, C. BEYER, E. GRAF, F. KUBEL and E. DOELKER
"Methodology for a better evaluation of the relation between mechanical strength of solids and polymorphic form" 
J. Pharm. Pharmacol. 41, 79-82  (1989)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Influence of emulsifiers on film formation from cellulose acetate latexes. 
II. Modeling approach to the fate of emulsifiers in highly plasticized films" 
J. Appl. Polym. Sci.  37,  173-182  (1989)

K.V. RANGA RAO, K. PADMALATHA DEVI and P. BURI
"Cellulose matrices for zero-order release of soluble drugs" 
Drug Dev. Ind. Pharm. 14, 2299-2320 (1988)

K. PADMA LATHA DEVI, K. V. RANGA RAO, S.K. BAVEJA, T. LEEMANN and P. DAYER
"Determination of alprenoloi and metoprolol in plasma by column liquid chromatography" 
J. Chromat. - Biomedical Applications - 434,  265-270  (1988)

S. KOPP, C. BEYER, E. GRAF, F. KUBEL and E. DOELKER
"McSgIiche Fehiinterpretationen bei Thermoanalyse-Diagrammen am Beispiel von polymorphem Phenobarbital" 
Acta Pharm. Technol. 34, 213-217 (1988)

K.V. RANGA RAO and K. PADMA LATHA DEVI
"Swelling controlled-release systems : recent developments and applications" 
Int. J. Pharm. 48, 1-13  (1988)

K.V. RANGA RAO and P. BURI
"Studies on factors affecting the bioadhesion of coated microparticles " 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 103-104 (1988)

K.V. RANGA RAO, K. PADMALATHA DEVI, F. KUBEL and P. BURI
"Studies on factors affecting the release of drugs through cellulose matrices" 
Proceed. Intern. Symp. Control. Rel. Biocat. Mater. 15, 101-102 (1988)

F. LESCURE, R. GURNY, E. DOELKER and J. AUGUSTYNSKI
" In vitro evaluation of a new electrophoretically controlled drug delivery system based on a crosslinked gel" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 362-363 (1988)

J. KREUTER, R. DIEPOLD, G. ANDERMANN, R. GURNY, V. H. L. LEE, J. R. ROBINSON, M. F. SAETTONE and O. E. SCHNAUDIGEL
"Comparison of different in-vitro and in-vivo test-models for pilocarpine using conventional and depot eyedrops (nanoparticles)" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 203-204 (1988)

B. GANDER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Macromolecular network characteristics and their effect on drug release from cross-linked poly(vinyl alcohol) micromatrices " 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 109-110 (1988)

F. LESCURE, R. GURNY, E. DOELKER, M. L. PELAPRAT, D. BICHON and J. M. ANDERSON
"Evaluation of new poly(glutamic acid esters) from implantable drug delivery systems" Proceed, intern. Symp. Control. Rel. Bioact. Mater. 15, 107-108 (1988)

V. BELTRAMI, R. GURNY and E. DOELKER
"Drug loading conditions for highly dosed crosslinked PVA matrices with controlled release properties" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 46-47 (1988)

E. DOELKER
"Recent advances in tableting science" 
Bollettino Chimico Farmaceutico 127, 37-49 (1988)

H. IBRAHIM, P. BURI and R. GURNY
"Composition, structure et paramètres physiologiques du système lacrymal impliqués dans la conception des formes ophtalmiques" 
Pharm. Acta Helv. 63, 146-154 (1988)

A. C. VIAL-BERNASCONI, E. DOELKER and P. BURI
"Gélules à libération prolongée : formes divisées et monolithiques" 
S.T.P. Pharma 4, 397-409 (1988)

E. DOELKER and A. C. VIAL-BERNASCONI
"Interactions contenant-contenu au sein des capsules gélatineuses et évaluation critique de leurs effets sur la disponibilité des principes actifs" 
S.T.P. Pharma 4, 298-306 (1988)

C. ROBERT, P. BURI and N. A. PEPPAS
"Experimental method for bioadhesive testing of various polymers " 
Acta Pharm. Technol. 34, 95-98 (1988)

T. NOOK, E. DOELKER and P. BURI
"Intestinal absorption kinetics of various model drugs in relation to partition coefficients" 
Int. J. Pharm., 43, 119-129 (1988)

J.-J. SCHAER, L. RECLARU and E. DOELKER %
"Study of adsorption and desorption of drugs on solids by a dynamic method" 
Acta Pharm. Technol. 34, 32-37 (1988)

B. GANDER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Crosslinked poly(alkylene oxides) for the preparation of controlled release micromatrices" 
J. Control. Release 5, 271-283 (1988)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Influence of emulsifiers on film formation from cellulose acetate latexes. 
I. Experimental study of phase separation phenomena due to sodium sulfate" 
J. Appl. Polym. Sci.,  34,  2631-2647  (1987)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Osmotic wate;qtransport through cellulose acetate membranes produced from a latex system" 
J. Pharm. Sci.,  76,  455-460  (1987)

T. NOOK, E. DOELKER and P. BURI
"Rôle de la bile et des sels biliaires dans l'absorption des médicaments" 
Pharm. Acta Helv. 62, 274-281 (1987) 

C. BINDSCHAEDLER and N. A. PEPPAS
"Detachment of small axisymmetric particles from fluid-liquid interfaces" 
Chem. Engin. Sci. 42, 2531-2546 (1987)

C. GABUS-SANNIE and P. BURI
"Etude comparative des méthodes de détermination du volume d'eau absorbé lors de perfusion de l'intestin grêle du rat" 
S.T.P. Pharma 3, 856-860 (1987)

R. GURNY, H. IBRAHIM, A. AEBI, P. BURI, C.G. WILSON, N. WASHINGTON, P. EDMAN and O. CAMBER
"Design and evaluation of controlled release systems for the eye" 
J. Control. Release 6, 367-373 (1987) 

R. GURNY, H. IBRAHIM, T. BOYE and P. BURI
"Latices and thermosensitive gels as sustained delivery systems to the eye" 
in: Ophthalmic Drug Delivery. Biopharmaceutical, technological and clinical aspects, M.F. Saettone, M. Bucci and P. Speiser eds, Fidia Research Series, Liviana Press, Padova, Vol. II, pp 27-36 (1987)

E. DOELKER, R. GURNY, J. SCHURZ, A. JXNOSI and N. MATIN
"Degrees of crystallinity and polymerization of modified cellulose powders for direct tableting" 
Powder Technology 52, 207-213 (1987)

H. IBRAHIM, T. BOYE, M. WERMEILLE, R. GURNY and P. BURI
"Determination of pilocarpine by HPLC in presence of isopilocarpine and a pH-sensitive polymer in ophthalmic dispersions" 
J. Pharm. Biomed. Anal.,  5, 379-382  (1987)

E. DOELKER, D. MORDIER, H. ITEN and P. HUMBERT-DROZ
"Comparative tableting properties of sixteen microcrystalline celluloses" 
Drug Dev. Ind. Pharm. 13, 1847-1875 (1987)

T. NOOK, E. DOELKER and P. BURI
"Intestinal absorption of nine drugs from oily vehicles and its relation to partition phenomena" 
Acta Pharm. Technol. 33, 115-119 (1987)

C. ROBERT, P. BURI and N. A. PEPPAS
"Influence of the drug solubility and dissolution medium on the release from poly(2-hydrocyethylmethacrylate) microspheres" 
J. Control. Release 5, 151-157.(1987)

E. DOELKER
"Water-swollen cellulose derivatives in pharmacy" 
in: Hydrogels in Medicine and Pharmacy, N.A. Peppas ed., CRC Press, inc., Boca Raton, Florida, Vol. II, Chap. 5, pp 115-160 (1987)

O. CAMBER, P. EDMAN and R. GURNY
"Influence of sodium hyaluronate on the miotic effect of pilocarpine in rabbits" 
Current Eye Research 6(6), 779-784 (1987)

E. DOELKER
"Proposition de classification des polymères biocompatibles pour les formes médicamenteuses à libération contrôlée" 
S.T.P. Pharma 3, 207-215 (1987)

P. BURI
"Définition et classification des systèmes matriciels" 
S.T.P. Pharma 3, 193-199 (1987)

C. KOLLER and P. BURI
"Propriétés et intérêt pharmaceutique des gels thermo réversibles à base de poloxamers et poloxamines" 
S.T.P. Pharma 3, 115-124 (1987)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Mechanically strong films produced from cellulose acetate latexes" 
J. Pharm. Pharmacol. 39, 335-338  (1987)

F. GUMOWSKI, E. DOELKER and R. GURNY
"The use of a new redispersible aqueous enteric coating material" 
Pharm. Technol. 11(2), 26-32 (1987)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Osmotically controlled drug delivery systems produced from organic solutions and aqueous dispersions of cellulose acetate" 
J. Control. Release 4, 203-212 (1986) 

T. HARMIA, J. KREUTER, P. SPEISER, T. BOYE, R. GURNY and A. KUBIS
"Enhancement of the myotic response of rabbits with pilocarpine-loaded polybutylcyanoacrylate nanoparticles" 
Int. J. Pharm. 33, 187-193 (1986)

B. GANDER, R. GURNY and E. DOELKER
"Crosslinked poloxamers as a versatile monolithic drug delivery system" 
Drug Dev. Ind. Pharm. 12, 1613-1623 (1986)

C. ROBERT and P. BURI
"Le mucus et son rôle dans l'absorption des médicaments" 
Pharm. Acta Helv. 61, 210-214 (1986)

C. DOELKER, E. DOELKER, P. BURI and L. WAGINAIRE
"The incorporation and in vitro release profiles of liquid, deliquescent or unstable drugs with fusible excipients in hard gelatin capsules" 
Drug Dev. Ind. Pharm. 12, 1553-1565 (1986) 

P. BURI, A.C. VIAL-BERNASCONI and C. DOELKER
"Modulation de la cinétique et de la vitesse de libération par un choix adéquat de l'excipient : Exemple des Gélucire" 
B.T. Gattefossé. 78, 67-73 (1985)

E. DOELKER
"Systèmes matriciels et libération d'ordre zéro : Le rôle de l'excipient" 
B.T. Gattefossé. 78, 51-60 (1985)

B. GANDER, R. GURNY and E. DOELKER
"Matrices à libération contrôlée par le gonflement du polymère. 
Partie I : Mécanismes de pénétration des solvants dans les polymères" 
Pharm. Acta Helv. 61, 130-134 (1986)
Partie II : Préparation des systèmes médicamenteux et analyse de la cinétique de libération" 
Pharm. Acta Helv. 61, 178-184 (1986)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Processus de formation de films semi-perméables d 'acétate de cellulose à partir de solutions organiques et de dispersions aqueuses submicroscopiques, rôle du tensio-actif dans les phénomènes de séparation de phases" 
4e Congrès International de Technologie Pharmaceutique APGI, Vol V, 123-132, Paris (1986) 

R. GURNY, F. GUMOWSKY and E. DOELKER
"Enrobage entérique avec une nouvelle forme de latex redispersible d'acétophtalate de cellulose" 
4e Congrès International de Technologie Pharmaceutique APGI, Vol. V, 117-122, Paris (1986) 

H. IBRAHIM, R. GURNY and P. BURI
"Méthodologie pour le choix de solvants dans la fabrication de pseudo-latex à base d'acétophtalate de cellulose" 
4e Congrès International de Technologie Pharmaceutique APGI, Vol. IV, 282-290, Paris (1986)

N.A. PEPPAS and P. BURI
"Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues" 
J. Control. Release 2, 257-275 (1985)

C. BINDSCHAEDLER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Thermodynamics of swelling of polymer latex particles by a water-soluble solvent 
II. Experimental results on cellulose acetate latices" 
J. Colloid Sci. 108, 83-94  (1985)

C. BINDSCHAEDLER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Thermodynamics of swelling of polymer latex particles by a water-soluble solvent 
I. Theoretical considerations" 
J. Colloid Interface Sci. 108, 75-82  (1985) 

B. GANDER, K. VENTOURAS, R. GURNY and E. DOELKER
"In vitro dissolution medium with supramicellar surfactant concentration and its relevance for in vivo absorption" 
Int. J. Pharm. 27, 117-124 (1985)

R.GURNY, T. BOYE, H. IBRAHIM and P. BURI
"Recent developments in controlled drug delivery to the eye" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 12, 300-301 (1985) 

R. GURNY, T. BOYE and H. IBRAHIM
"Ocular therapy with nanoparticulate systems for controlled drug delivery" 
J. Control. Release, 2, 353-361 (1985)

B. GANDER, R. GURNY and E. DOELKER
"Einfluss der Zerfallseigenschaften von Tabletten auf die Freigabe und Absorption einer quasi unloslichen Model lsubstanz" 
Acta Pharm. Techn. 31, 77-84 (1985)

H.K. CHAN and E. DOELKER
"Polymorphic transformation of some drugs under compression" 
Drug Dev. Ind. Pharm. II, 315-332 (1985)

C. BINDSCHAEDLER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Equilibrium behaviour of polymer particles in ternary emulsion systems" 
Makromol. Chem., Rapid Commun. 6, 267-270 (1985) 

P. BURI
"Les nouvelles formes médicamenteuses" 
Les entretiens du Caria, p. 83 (1982/1983)

C. ROBERT and P. BURI
"Effect of degree of crosslinking on water transport in polymer microparticles" 
J. Appl. Polymer Sci. 30, 301-306  (1985)

P. BURI
"Formulation, caractéristiques et intérêt des formes galéniques orales à libération prolongée de type matrice" 
Boll. Chim. Farm. 123, 453-464 (1984)

R. GURNY, J.M. MEYER and N.A. PEPPAS
"Bioadhesive intraoral release systems: design, testing and analysis" 
Biomaterials 5, 336-340 (1984)

T. BOYE, R. GURNY and P. BURI
"Développement et évaluation d'un nouveau type de forme ophtalmique à libération prolongée" 
2e Congrès Européen de Biopharmacie et Pharmacocinetique Salamanca (avril 1984)

R. GURNY
"Bioadhesive intraoral Release Systems" 
in: Polymeric Biomaterials Proc. NATO Advanced Study institute on Biopolymers, 212-220, Izmir (1984)

R. GURNY
"Controlled Drug Delivery with Colloidal Polymeric Systems" 
in: Polymeric Biomaterials Proc. NATO Advanced Study institute on Biopolymers, 195-211, Izmir (1984)

N.A. PEPPAS, P.J. HANSEN and P. BURI
"A theory of molecular diffusion in the intestinal mucus" 
Int. J. Pharm. 20, 107-118 (1984)

P. BURI
"Mesure de la vitesse de dissolution pour l'amélioration et le contrôle de la qualité des médicaments" 
J. Pharm. & Biomed. Analysis 1, 393-402  (1983)

P. BURI and J. HUMBERT-DROZ
"Solubilisation de principes actifs insolubles par des constituants des sucs digestifs" 
Labo-Pharma - Probl. Tech. 32, 197-199 (1984)

R. GURNY
"Latex Systems" 
in : Topics in Pharmaceutical Sciences, 277-288  (1983)

E. DOELKER
"Developments in compression: Compressional tests as an aid in tablet formulation" 
in : Topics in Pharmaceutical Sciences, 371-385  (1983) 

R.W. KORSMEYER, R. GURNY, E. DOELKER, P. BURI and N.A. PEPPAS
"Mechanisms of Potassium Chloride Release from Compressed, Hydrophilic, Polymeric Matrices ; Effect of Entrapped Air" 
J. Pharm. Sci. 72, 1189-1191  (1983) 

P. HUMBERT-DROZ, R. GURNY, D. MORDIER and E. DOELKER
"Densification behaviour of drugs presenting availability problems" 
Int. J. Pharm. Tech. & Prod. Mfr. 4, 29-35 (1983)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Notions théoriques sur la formation des films obtenus à partir de microdispersions aqueuses et application à l'enrobage" 
Labo-Pharma - Probl. Tech. 31, 389-394 (1983)

R. GURNY, E. DOELKER, P. BURI, R.W. KORSMEYER and N.A. PEPPAS
"Nouvelles observations sur le mécanisme de libération d'un soluté à partir de polymères hydrophiles" 
3e Congrès International de Technologie Pharmaceutique APGI, Vol. II, 97-105, Paris, 1983

R.W. KORSMEYER, R. GURNY, E. DOELKER, P. BURI and N.A. PEPPAS
"Mechanisms of solute release from porous hydrophilic polymers" 
Int. J. Pharm. 15, 25-35 (1983)

P. HUMBERT-DROZ, D. MORDIER and E. DOELKER
"Densification Behaviour of Powder Mixtures" 
Acta Pharm. Techn. 29, 69-73 (1983)

N.A. PEPPAS and R. GURNY
"Relation entre la structure des polymères et la libération contrôlée de principes actifs" 
Pharm. Acta Helv. 58, 2-8 (1983)

J. CHEHADE, R. GURNY, E. DOELKER and P. BURI
"Aqueous Coating with the Laboratory Apparatus Hi-Coater® HCT-20 Mini" 
Acta Pharm. Techn. 28, 141-148 (1982)

R. GURNY and W. KLOETI
"A New Device for Measuring the Miotic Response to Drugs. 
1. Preliminary Communication" 
Pharm. Acta Helv. 57, 274-275  (1982)

C. BINDSCHAEDLER and R. GURNY
"Optimisation de formulations pharmaceutiques par la méthode du Simplex au moyen d'une calculatrice TX 59" 
Pharm. Acta Helv. 57, 251-255 (1982)

C. DOELKER and E. DOELKER
"Comprimés à libération prolongée : mécanisme prépondérant de libération d'un traceur à partir de matrices de glycérides totaux et partiels" 
Pharm. Acta Helv. 57, 189-192 (1982) 

P. HUMBERT-DROZ, D. MORDIER and E. DOELKER
"Méthode rapide de détermination du comportement à la compression pour des études de préformulation" 
Pharm. Acta Helv. 57, 136-143 (1982)

M. BOYMOND-GENOUD, G. EIDE-JURGENSEN, D. MORDIER, E. DOELKER and P. BURI
"Importance du mouillage dans le processus de libération des principes actifs hydrophobes incorporés dans des gélules 
II. Désagrégation, dissolution et biodisponibilité chez l'homme" 
J. Pharm. Belg. 37  (2), 135-140  (1982)

R. GURNY, E. DOELKER and N.A. PEPPAS
"Modelling of sustained release of water-soluble drugs from porous, hydrophobic polymers" 
Biomaterials 3, 27-32 (1982)

A. DOMMEYER, J. BOUCHERAT and P. BURI
"Relations entre les propriétés physico-chimiques du tolbutamide seul ou coprecipité avec la polyvinylpyrrolidone et ses caractéristiques de dissolution" 
Acta Pharm. Techn. 27, 205-210 (1981)

E. DOELKER, C. DOELKER and D. MORDIER
"Importance du mouillage dans le processus de libération des principes actifs hydrophobes incorporés dans des gélules. 
1. Diffusion du milieu dans la paroi et pénétration capillaire dans la poudre" 
J. Pharm. Belg. 36  (6), 404-411  (1981)

P. BURI, E. DOELKER and J. BOUCHERAT
"Dissolution in vitro : un critère d'évaluation des formes médicamenteuses à libération prolongée" 
Schweiz. RundschauMed. (PRAXIS) 70 (29), 1310-1313 (1981)

R. GURNY, W. KLOETI and P. BURI
"Développement d'un systeme électro-optique permettant la mesure continue du diametre pupillaire" 
Premier Congrès Europeen de Biopharmacie et Pharmacocinetique - Pharmacocinetique experimentale Vol. 2, 398-402, Clermont-Ferrand  (avril 1981)

E. DOELKER and P. BURI
"Formulation des comprimés à libération prolongée.  III. Matrices lipidiques" 
Pharm. Acta Helv. 56, 111-118 (1981)

R.  GURNY
"Preliminary Study of Prolonged Acting Drug Delivery System for the Treatment of Glaucoma. 
Pharm. Acta Helv. 56, 130-132 (1981) 

P. BURI, E. DOELKER and J. BOUCHERAT
"Comparative in vitro Evaluation of six Commercial Vincamine Prolonged-released Dosage Forms" 
J. Clin. Hosp. Pharm. 6, 101-105  (1981)

R. GURNY, G.S. BANKER and P. BURI
"Développement d'un injectable de testostérone à action prolongée à base de latex biodégradable" 
III Congreso Nacionali Congrès hispano-français de Biopharmacie et Pharmacocinétique Tome 2, 173-179, Barcelona (1979)

P. BURI
"Emploi des polymères pour la fabrication des matrices hydrophiles et insolubles" 
ALPI, Lille (1981)

P. BURI
"Préformulation : pKa et coefficient de partage" 
Labo-Pharma - Problèmes et Techniques 307, 181-186 (1981)

C. GARCIN-SALOMON, J. BOUCHERAT, C. CREVOISIER and P. BURI
"The influence of Sodium Taurocholate (TCNa) on the Absorption of Salicylic Acid from the Rat Small Intestine" 
Pharm. Acta Helv. 56, 78-81 (1981)

R. GURNY, N.A. PEPPAS, D.D. HARRINGTON, G.S. BANKER
"Development of Biodegradable and injectable Latices for Controlled Release of Potent Drugs" 
Drug. Dev. Ind. Pharm. 7, 1-25 (1981) 

C. BOYMOND, E. DOELKER and P. BURI
"Influence de la formulation et de la méthode de préparation sur les caractéristiques de structure, de pénétration capillaire et de libération des matrices à base d'éthylcellulose" 
Pharm. Acta Helv. 56, 26-30 (1981)

N.A. PEPPAS, R. GURNY, E. DOELKER and P. BURI
"Modelling of Drug Diffusion through Swellable Polymeric Systems" 
J. Membr. Sci 7,  241-253  (1980)

J.L. YAEGER, R. GURNY, M.A. GONZALEZ, R. SJOQVIST and G.S. BANKER
"Bioavailability Assessment of Polymer interacted Dectropropoxyphene from Rectal Dosage Forms" 
(1st communication : "Entrapment Procedure and Blood Assay of Dextropropoxyphene") 
Pharm. Ind. 42, 1141-1143 (1980)

E. DOELKER, R. GURNY and D. MORDIER
"Effect of the Type of Binder on the Work involved in the Compression of Granulations" 
Acta Pharm. Techn. 26, 155-158 (1980) 

P. BURI and E. DOELKER
"Formulation des comprimés à libération prolongée.  II.  Matrices hydrophiles" 
Pharm. Acta Helv. 55, 189-197 (1980)

J.-L. SALOMON and E. DOELKER
"Formulation des comprimés à libération prolongée. I. Matrices inertes" 
Pharm. Acta Helv. 55, 174-182 (1980)

P. BURI
"Progrès récents dans le domaine des formes ophtalmiques et de leur contrôle" 
(1980)

P. BURI and C. SANNIE
"Utilisation de systèmes lipidiques pour améliorer l'absorption de médicaments liposolubles" 
(1980)

P. BURI
"Les nouveaux systèmes thérapeutiques : intérêt, applications, perspectives" 
Médecine et Hygiène 38, 962-968 (1980)

R. GURNY, M.A. GONZALEZ, G.S. BANKER and D.O. KILDSIG
"The Determination of the Entrapment Efficiency for a Molecular Dispersion System" 
Drug Dev. Ind. Pharm. 5, 437-445 (1979)

R. GURNY, S.P. SIMMONS, G.S. BANKER, R. MEEKER and R.D. MYERS
"A New Biocompatible Drug Delivery System for Chronic implantation in Animal Brain" 
Pharm. Acta Helv. 54, 349-352 (1979)

M.-H. RUTZ-COUDRAY, J. GIUST and P. BURI
"Libération prolongée, par inclusion dans une matrice inerte, de la drotavérine coprécipitée" 
Pharm. Acta Helv. 54, 363-365 (1979)

M.-H. RUTZ-COUDRAY, L. BALANT and P. BURI
"Utilité de l'analyse compartimentale pour le développement de formes galéniques à libération prolongée: expériences avec la drotavérine chez l'homme" 
Pharm. Acta Helv. 54, 210-213 (1979)

C. GARCIN-SALOMON, E. DOELKER, C. CREVOISIER and P. BURI
"Interaction entre le taurocholate de sodium et deux dérives salicylés : comparaison des informations apportées par différentes techniques" 
(3e communication : "Dialyse dynamique" 
Pharm. Acta Helv. 54, 206-209 (1979)

J.-L. SALOMON, E. DOELKER and P. BURI
"Sustained Release of a Water-Soluble Drug from Hydrophilic Compressed Dosage Forms" 
Pharm. Ind. 41, 799-802 (1979)

J. GRUENBERG, D. CORAL, A.L. KNUPFER and J. DESHUSSES
"Interactions of liposomes with trypanosoma brucei plasma membrane" 
Biochem. Biophys. Res. Commun. 88, 1173-1179 (1979)

C. GARCIN-SALOMON, E. DOELKER, C. CREVOISIER and P. BURI
"Interaction entre le taurocholate de sodium et deux dérives salicylés : comparaison des informations apportées par différentes techniques" 
(2e communication : "Dialyse à l'équilibre") 
Pharma Acta Helv. 54, 160-163 (1979)

C. GARCIN-SALOMON, E. DOELKER, C. CREVOISIER and P. BURI
"Interaction entre le taurocholate de sodium et deux dérives salicylés : comparaison des informations apportées par différentes techniques" 
(lère communication : "Méthode des solubilités") 
Pharm. Acta Helv. 54, 157-159 (1979)

J.L. SALOMON, P. VUAGNAT, E. DOELKER and P. BURI
"Importance de la technologie et de la formulation pour le mécanisme de libération du chlorure de potassium contenu dans des matrices hydrophiles" 
(2e communication : Influence de la force de compression, de la granulométrie du traceur et de l'épaisseur du comprimé") 
Pharm. Acta Helv. 54, 86-89 (1979)

J.-L. SALOMON, E. DOELKER and P. BURI
"Importance de la technologie et de la formulation pour le mécanisme de libération du chlorure de potassium contenu dans des matrices hydrophiles" 
(lère communication :"Influence de la viscosité et du pourcentage de gélifiant") 
Pharm. Acta Helv. 54, 82-85 (1979)

K. VENTOURAS and P. BURI
"Rôle de l'acidification de matrices hydrophiles sur la libération de principes actifs peu solubles en milieu intestinal" 
Pharm. Acta Helv. 53, 314-320 (1978)

E. DOELKER
"Physique de la compression, intérêt et limite des machines instrumentées pour l'optimisation de la formulation" 
Pharm. Acta Helv. 53, 182-188 (1978) 

E. DOELKER
"Mécanismes de libération des principes actifs à partir de microcapsules à action prolongée" 
Labo-Pharma - Problèmes et Techniques 281, 915-922 (1978) 

K. VENTOURAS, A. de PERROT and P. BURI
"Les modèles hydrodynamiques multicompartimentaux dans la recherche et l'enseignement :  applications pratiques" 
Pharm. Acta Helv. 53, 147-155 (1978)

P. BURI and E. DOELKER
"Equivalences des médicaments" 
Médecine et Hygiène 36, 1008 (1978)

R. GURNY, M. BOYMOND-GENOUD and P. GUITARD
"Analyse par régression multiple de l'influence de la faille des particules et de la présence de lactose sur la dissolution de capsules gélatineuses de phénacetine et d'acétanilide" 
J. Pharm. Belg. 33  (1), 6-10  (1978)

R. GURNY, P. BURI, H. SUCKER; P. GUITARD and H. LEUENBERGER
"Réalisation et développement théorique de formes médicamenteuses à libération contrôlée par des films méthacryliques" 
(4e communication : "Etude par régression linéaire multiple de facteurs technologiques influençant la libération d'un principe actif à partir de microgranules enrobées par fluidisation") 
Pharm. Acta Helv. 52, 247-251 (1977)

R. GURNY, P. GUITARD, P. BURI and H. SUCKER
"Réalisation et développement théorique de formes médicamenteuses à libération contrôlée par des films méthacryliques" 
(3e communication : "Préparation et caractérisation de formes galéniques à libération contrôlée" 
Pharm. Acta Helv. 52, 182-187 (1977)

J.-L. SALOMON and E. DOELKER
"Porosité des comprimés, importance et méthodes de détermination" 
Labo-Pharma - Problèmes et Techniques 272, 51-56 (1978) 

P. BURI
"Les méthodes d 'évaluation de la vitesse de libération des principes actifs in vitro" 
Journal Suisse de Pharmacie 116, 55-62 (1978)

R. GURNY, P. BURI, H. SUCKER, P. GUITARD and H. LEUENBERGER
"Réalisation et développement de formes médicamenteuses à libération contrôlée par des films méthacryliques 
(2e communication :"Etude par analyse orthogonale des facteurs influençant le transport à travers un film plan") 
Pharm. Acta Helv. 52, 175-181 (1977)

R. GURNY, P. GUITARD, P. BURI and H. SUCKER
(3e communication : "Préparation et caractérisation de formes galéniques à libération contrôlée") 
Pharm. Acta Helv. 52, 182-187 (1977)

P. BURI and K. VENTOURAS
"Aspect nouveau de la libération contrôlée : Les médicaments-réservoirs" 
16e Colloque de Pharmacie Industrielle, Gand (1977)

A. SAUTTER, E. DOELKER, P. BURI and D. MORDIER
"Etude du transport de principes actifs incorporés dans des émulsions liquides de type huile dans eau" 
(3e partie  : "Influence de quelques paramètres de formulation") 
J. Pharm. Belg. 32, 379-387  (1977)

K. VENTOURAS, L. BALAND, C. REVILLARD and P. BURI
"Application de l 'analyse multicompartimentale à la pharmacocinétique de la vincamine chez l'homme" 
Pharm. Acta Helv. 52, 97-105 (1977)

L. BALANT, C. REVILLARD and K. VENTOURAS
"Absorption gastro-intestinale et analyse multicompartimentale sur ordinateurs" 
Pharm. Acta Helv. 52, 89-95 (1977)

K. VENTOURAS, J. BOUCHERAT and P. BURI
"Influence des facteurs technologiques sur la libération de la vincamine incorporée dans des matrices hydrophiles" 
Pharm. Acta Helv. 52, 119-123 (1977)

A. SAUTTER, E. DOELKER, P. BURI and D. MORDIER
"Etude du transport de principes actifs incorporés dans des émulsions liquides de type huile dans eau" 
(2e partie :"Modèles cinétiques et cellule de diffusion") 
J. Pharm. Belg. 32,  229-240  (1977)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthesized for Direct Batch Operations" 
(4th communication: "Comparative studies on the release of the substance in vitro during various technological processes" 
Pharm. Ind. 39 (5), 512-515 (1977)

E. DOELKER and E. SHOTTON
"The effect of some binding agents on the mechanical properties of granules and their compression characteristics 
J. Pharm. Pharmac. 29,  193-198  (1977)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthersized for Direct Batch Operation" 
(3rd communication : "Effect of the physical characteristics of an active substance on its conversion into a dosage form") 
Pharm. Ind. 39 (3), 281-284 (1977)

R. GURNY, P. GUITARD and P. BURI
"Bestimmung der Wasserdampfpermeabilitat von Methacrylatcopolymeren verschiedener Zusammensetzung" 
Acta Pharm. Techn. 23 (1), 29-38 (1977)

R. GURNY, D. MORDIER and P. BURI
"Réalisation et développement théorique de formes médicamenteuses à libération contrôlée par des films méthacryliques" 
(lère communication : "Fabrication et évaluation de films plans libres") 
Pharm. Acta Helv. 51, 383-390 (1976)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthesized for Direct Batch Operations" 
(2nd communication:Transformation of the physical characteristics of (+) -cyanidanol-3 ) 
Pharm. Ind. 38 (12), 1175-1178 (1976)

K. VENTOURAS, P. SCHULZ, E. DOELKER, J. BOUCHERAT and P. BURI
"Etude pharmacocinétique de la vincamine administrée par voie orale" 
Pharm. Acta Helv. 51, 334-342 (1976)

R. GURNY, C. REVILLARD and E. DOELKER
"Computation of the RRSW Distribution by the Maximum Likelihood Method for Drug Release from Solid Dosage Forms" 
Pharm. Ind. 38 (10), 913-914 (1976)

C. CREVOISIER
"Résorption percutanée" 
Journal Suisse de Pharmacie 114, 421-425 (1976)

P. BURI
"Aspect biopharmaceutique des médicaments à libération contrôlée" 
Journal Suisse de Pharmacie 114, 405-411 (1976)

M.H. RUTZ-COUDRAY, L. BALANT, C. REVILLARD, P. BURI and J. GIUST
"Pharmacocinétique de la drotaverine chez l'homme" 
Pharm. Acta Helv. 51, 258-263 (1976)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthesized for Direct Batch Operation" 
(1st communication : "Study of the Drying Characteristics of (+)-Catechin") 
Pharm. Ind. 38 (5), 484-488 (1976)

M. ROUILLER, R. GURNY and E. DOELKER
"Possibilités de production avec un appareil à lit fluidisé de laboratoire" 
Acta Pharm. Techn. 22 (1) 55-68 (1976)

K. VENTOURAS and P. BURI
"Libération in vitro du sulfate de lithium incorpore à des matrices hydrophiles" 
Pharm. Acta Helv. 51, 212-218 (1976)

C. CREVOISIER and P. BURI
"Facteurs physico-chimiques susceptibles d'influencer l'absorption gastro-intestinale après dissolution des principes actifs" 
Pharm. Acta Helv. 51, 193-202 (1976)

A. SAUTTER, E. DOELKER, P. BURI and D. MORDIER
"Etude du transport de principes actifs incorporés dans des émulsions liquides de type huile dans eau"
(lere partie :"Caractérisation et contrôle du modèle d'émulsions par le compteur de Coulter") 
J. Pharm. Belg. 31 (3), 287-294  (1976)

R. GURNY
"Perméabilité à la vapeur d'eau de polymères, sous forme de films libres, utilisés pour l'enrobage" 
Pharm. Acta Helv. 51, 1-10 (1976)

J. BARRELET, M. TSACOPOULOS and P. BURI
"Cornea preparation for in vitro biopharmaceutical evaluation of ophthalmic dosage forms" 
J. Pharm. Pharmac. 27,  919-922  (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes a travers des membranes artificielles et biologiques" 
(5e communication ; "Etude du transport in situ à travers l'intestin grêle du rat") 
Pharm. Acta Helv. 50, 231-236 (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes à travers des membranes artificielles et biologiques" 
(4e communication :"Etude du transport in vitro à travers la paroi intestinale du rat et étude critique de la méthode du sac eversé") 
Pharm. Acta Helv. 50, 192 (1975)

P. BURI and C. CREVOISIER
"Emploi et intérêt des membranes dans la recherche pharmaceutique" 
Ets Gattefossé, F-69800 St. Priest (France) Bulletin Technique N° 68, 3-11 (1973/1974)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes à travers des membranes artificielles et biologiques" 
(3e communication :"Etude du transport in vitro à travers des membranes liquides organiques dans un modèle à trois phases") 
Pharm. Acta Helv. 50, 159-164 (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes à  travers des membranes artificielles et biologiques" 
(2e communication "Etude du transport in vitro à travers des membranes lipidiques composées") 
Pharm. Acta Helv. 50, 103-108 (1975)

E. DOELKER and P. BURI
"Une technique récente en pharmacie galénique, le micro-encapsulage" 
Pharm. Acta Helv. 50, 73-87 (1975)

E. DOELKER, H. SCHWYTER and D. MORDIER
"Evaluation biopharmaceutique de quelques comprimés d'acide acétylsalicylique. - Importance de la méthode de dissolution dans l'établissement de corrélations in vivo - in vitro. 
Pharm. Acta Helv. 50, 24-27 (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes  à travers des membranes artificielles et biologiques" 
(lere communication : "Etude du transport in vitro à travers des membranes de cellophane") 
Pharm. Acta Helv. 49, 140-151 (1974)

M. ROUILLER, R. GURNY and E. DOELKER
"Possibilités de production avec un appareil à lit fluidisé de laboratoire" 
Acta Pharm. Techn. 21 (2), 129-138 (1975)

K. VENTOURAS, P. DICK and P. BURI
"Etude d'une nouvelle forme galénique à action prolongée de sulfate de lithium" 
Journal Suisse de Médecine 103 (24), 878-881 (1973)

G.  JURGENSEN-EIDE
"Influence of complex formation on drug release from tablets" 
Acta Pharm. Suec. 10, 229-246 (1973)

E.  DOELKER and P. BURI
"Etude de la libération in vitro d'une amine salifiée par un polyélectrolyte hydrosoluble" 
(3e communication : "Comparaison avec d'autres types de gels et considérations sur le mécanisme de libération") 
Pharm. Acta Helv. 48, 287-296 (1973)

E.  DOELKER and P. BURI
"Etude de la libération in vitro d'une amine salifiée par un polyélectrolyte hydrosoluble" 
(2e communication "Facteurs susceptibles d'influencer la vitesse de libération") 
Pharm. Acta Helv. 48, 166-180 (1973)

E.  DOELKER et P. BURI
"Etude de la libération in vitro d'une amine salifiée par un polyélectrolyte hydrosoluble" 
(1ère communication : "Vue actuelle du problème and mise au point d'un test in vitro") 
Pharm. Acta Helv. 47, 495-507 (1972)

P.  BURI 
"Biopharmacie et développement d'un médicament" 
Médecine et Pharmacie, numéro spécial 5, 740-746 (1971)

E. DOELKER and P. BURI
"Quelques aspects biopharmaceutiques des comprimés pour la voie orale" 
Médecine et Pharmacie, numéro spécial 5, 748-767 (1971)

E. DOELKER and P. BURI
"La chimiothérapie du cancer" 
Journal Suisse de Pharmacie 107, 8, 31, 56 (1969)

P. BURI
"Le pharmacien suisse à l'Université" 
Journal Suisse de Pharmacie 106, 442 (1968)

P.A. NUSSBAUMER, P. BURI and M. GENEQUAND
"Cholagogues et cholérétiques" 
Journal Suisse de Pharmacie 106, 798, 830, 900, 930 (1968)

C. CURDY, Y.N. KALIA, F. FALSON-RIEG and R.H. GUY
"Effect of metal ions on the recovery of human skin impedance in vivo after iontophoresis" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 391-392 (1999)

N. SEKKAT, R.H. GUY and Y.N. KALIA
"Comparing the barrier properties of in vitro porcine ear skin with human skin in vivo
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 427-428, Boston (USA), 1999

A. LOPEZ-CASTELLANO, R.H. GUY and M.B. DELGADO-CHARRO
"Effect of area on the iontophoretic transport of phenylalanine and propanolol across the skin" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 405-406, Boston (USA), 1999

I. ALBERTI, A. NAIK, Y.N. KALIA, J.-D. BONNY and R.H. GUY
" In vivo evaluation of topical delivery systems by Fourier transform infrared spectroscopy (FTIR)" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 475-476,1999

N. SEKKAT, R.H. GUY and Y.N. KALIA
"Developing in vitro models for skin barrier function in premature neonates" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 429-430,Boston (USA), 1999

G. MERINO, Y.N. KALIA, M.B. DELGADO-CHARRO, R.O. POTTS and R.H. GUY
"Sonophoresis: How does ultrasound enhance drug transport across the skin?" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 383-384,Boston (USA), 1999

D. MARRO, M.B. DELGADO-CHARRO, Y.N. KALIA and R.H. GUY
"Iontophoretic transport mechanisms: effect of background electrolyte and competing ions" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 26, 94-95,Boston (USA), 1999

J. BARRA, P. BUSTAMANTE and E. DOELKER
"Optimisation des propriétés des excipients pour formes solides par le concept des énergie de surface et des paramètres de solubilité" 
S.T.P. Pharma, 9 (hors-série), 19-22 (1999)

J. BARRA, F. FALSON-RIEG and E. DOELKER
"Influence of the organization of binary mixes on their compactibility" 
Pharmaceutical Research, 16 (9), 1449-1455 (1999)

J. BARRA, F. LESCURE and E. DOELKER
"Taste masking as a consequence of the organisation of powder mixes" 
Pharm. Acta Helv., 74(1), 37-42 (1999)

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY >
"Bioerodible devices based on poly(ortho esters) for controlled delivery of tetracycline to periodontal pocket" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 697-698 (1999)

S. EINMAHL, F. BEHAR-COHEN, C. TABATABAY and R. GURNY
"Evaluation of poly(ortho ester) for intraocular application in rabbits: biocompatibility assessement and in vitro degradation" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 679-680 (1999)

J. ACEVEDO-PEÑA , Y.N. KALIA, P. BURI, R.H. GUY, D. QUINTANAR-GUERRERO and A. GANEM-QUINTANAR
"Enhancing effects of Azone R and 4-decyl-oxazolidin-2-one ex vivo skin permeation" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 481-482 (1999)

F. VEUILLEZ, J. DESHUSSES, F. FALSON and P. BURI
"Topological distribution of a myristoylated peptide throughout the pig buccal mucosa during permeation" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 339-340 (1999)

I. ROSENDO-VALDES, Y.N. KALIA, P. BURI, R.H. GUY, D. QUINTANAR-GUERRERO and A. GANEM-QUINTANAR
"Enhancing effect of 1-dodecylazacycloheptan-2-one(AzoneR) and 4-decyl-oxazolidin-2-one on drug absorption across the buccal" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 26, 333-334 (1999)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, H. FESSI and E. DOELKER
"Pseudolatex preparation using a novel emulsion-diffusion process involving direct  displacement of partially water-miscible solvents by distillation" 
International Journal of Pharmaceutics., 188, 155-164 (1999)

M. BERTON, E. ALLÉMANN, CY A. STEIN and R. GURNY
"Highly loaded nanoparticulate carrier using an hydrophobic antisense  oligonuccleotide complex" 
Eur. J. Pharm. Sci., 9, 163-170 (1999)

J. HELLER, S.Y. NG, R-H SHEN, J. BARR, A. ROTHEN-WEINHOLD and R. GURNY
"Protein delivery from extruded poly(ortho esters)" 
Proceed. Asian Conference on Controlled Release, Hong Kong, , 132-133 (1999)

A. ROTHEN-WEINHOLD, K. BESSEGHIR and R. GURNY
"Production of biodegradable implants for the sustained release of pharmaceuticals" 
Proceed. Asian Conference on Controlled Release, Hong Kong, 72-73 (1999)

S. EINMAHL, F. BEHAR-COHEN, C. TABATABAY, D. CHAUVAUD, J.  HELLER and R. GURNY
"Poly(ortho ester) : A new biocompatible intraocular drug delivery system" 
Proceed. Asian Conference on Controlled Release, Hong Kong, , 70-71 (1999)

R. GURNY, A. ROTHEN-WEINHOLD and K. BESSEGHIR
"Biodegradable implants" 
Proceed. Asian Conference on Controlled Release, Hong Kong, 46-47 (1999)

N.M. RANJHA and E. DOELKER
"pH-sensitive noncrosslinked poly(vinyl alcohol-co-acrylic acid) hydrogels for site  specific drug delivery" 
Saudi Pharm. J. 7(3), 137-143 (1999)

E. DOELKER
"Caractères physicochimiques des principes actifs. Leurs conséquences sur la  faisabilité et la stabilité des formes galéniques" 
S.T.P. Pharma Prat. 9, 399-409 (1999)

A. ROTHEN-WEINHOLD, K. BESSEGHIR, E. VUARIDEL, E. SUBLET, N. OUDRY, F. KUBEL and R. GURNY
"Injection-molding versus extrusion as manufacturing technique for the preparation  of biodegradable implants" 
European Journal of Pharmaceutics and Biopharmaceutics, 48, 113-121 (1999)

N.M. RANJHA and E. DOELKER
"pH-sensitive hydrogels for site-specific drug delivery. II. Drug release behaviour  from crosslinked alkyl acrylates/methacrylic acid copolymers" 
S.T.P. Pharma Sci. 9, 341-349 (1999)

N.M. RANJHA and E. DOELKER
"pH-sensitive hydrogels for site-specific drug delivery. I. Swelling behaviour of  crosslinked copolymers of acrylic and methacrylic acid" 
S.T.P. Pharma Sci. 9, 335-340 (1999)

J. BARRA, P. BUSTAMANTE and E. DOELKER
"Use of the solubility parameter and surface energy concepts in the formulation of  solid dosage forms" 
S.T.P. Pharma Sci., 9 293-305 (1999)

S. EINMAHL, M. ZIGNANI, E. VARESIO, J. HELLER, J.-L. VEUTHEY, C. TABATABAY and R. GURNY
"Concomitant and controlled release of dexamethasone and 5-fluorouracil from  poly(ortho ester)"
International Journal of Pharmaceutics, 185, 189-198 (1999)

J. HELLER and R. GURNY
"Poly(ortho esters)" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz  (éd.), vol. 2, John Wiley & Sons, Inc, New York,  pp. 852-874, (1999)

F. DE JAEGHERE, E. DOELKER, and R. GURNY
"Nanoparticles" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz  (éd.), vol. 2, John Wiley & Sons, Inc, New York,  pp. 641-664, (1999)

O. FELT, V. BAEYENS, M. ZIGNANI, P. BURI and R. GURNY
"Mucosal drug delivery, ocular" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz (éd.), vol. 2, John Wiley & Sons, Inc, New York, pp. 605-626 (1999)

S. EINMAHL, A.A. DESHPANDE, C. TABATABAY and R. GURNY
"Mucosal drug delivery, intravitreal" 
in : Encyclopedia of Controlled Drug Delivery, 
E. Mathiowitz (éd.), vol. 2, John Wiley & Sons, Inc, New York, pp. 564-592, (1999)

F. VEUILLEZ, J. DESHUSSES and P. BURI
"Synthesis and characterization of an acylated di-peptide (Myr-Trp-Leu) with  modified transmucosal transport properties" 
European Journal of Pharmaceutics and Biopharmaceutics, 48, 21-26 (1999)

F. MOTTU, D.A. RÜFENACHT and  E. DOELKER
"Radiopaque polymeric materials for medical applications. Current aspects of biomaterial research." 
Invest. Radiol. 34 (5), 323-335 (1999)

F. DE JAEGHERE, E. ALLÉMANN, J. FEIJEN, T. KISSEL, E. DOELKER and R. GURNY
"Cellular uptake of nanoparticles made of poly(lactic acid), poly(ethylene oxide)  diblock and triblock copolymers"
Proceed. Int.'l Control. Rel. Bioact. Mater. 26, 685-686 (1999)

A. ROTHEN-WEINHOLD, N. OUDRY, K. SCHWACH-ABDELLAOUI, S. FRUTIGER-HUGHES, G.J. HUGHES, K. BESSEGHIR and R. GURNY
"How to avoid the formation of peptide impurities during manufacturing of implants  by melt-extrusion ? " 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 681-682 (1999)

A. ZIMMER, F. DELIE-SALMON and R. GURNY
"Application of fluorescence correlation spectroscopy for the characterization of drug  delivery systems" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 671-672 (1999)

O. FELT, C. MICHEL, P. BURI and R. GURNY
"Gamma scintigraphy as tool for the evaluation of precorneal residence time :  influence of the methodology" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 615-616 (1999)

G. MOLINARO, A. ADAM, M. ZIGNANI, J. TAILLEFER, K. SCHWACH-ABDELLAOUI, R. GURNY and J.C. LEROUX
"Evaluation of the local and systemic inflammatory responses induced by the  subcutaneous injection of different biopolymers" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 611-612 (1999)

F. DE JAEGHERE, E. ALLÉMANN, J. FEIJEN, E. DOELKER and R. GURNY
"Freeze-drying of PLA-PEO nanoparticles - from basic principles to rational optimization" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 573-574 (1999)

J. HELLER, S.Y. NG, J. BARR, R. GURNY, K. SCHWACH-ABDELLAOUI and E. SCHACHT
"Erosion, properties and drug release from a new family of poly(ortho esters)" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater. 26, 232-233 (1999)

O.  FELT, P. FURRER, J.M. MAYER, B. PLAZONNET, P. BURI and R. GURNY
"Topical use of chitosan in ophthalmology : tolerance assessment and evaluation of  precorneal retention" 
International Journal of Pharmaceutics, 180 (2), 185-193 (1999)

F. DE JAEGHERE, E. ALLÉMANN, J.-C. LEROUX, W. STEVELS, J. FEIJEN, E.DOELKER and R. GURNY
"Formulation and lyoprotection of poly(lactic acid-co-ethylene oxide) nanoparticles :  influence on physical stability and in vitro cell uptake" 
Pharmaceutical Research, 16(6), 859-866 (1999)

M. BERTON, L. BENIMETSKAYA, E. ALLÉMANN, C.A. STEIN and R. GURNY
"Uptake of oligonucleotide-loaded nanoparticles in prostatic cancer cells and their  intracellular localization" 
European Journal of Pharmaceutics and Biopharmaceutics, 47, 119-123 (1999)

P. FURRER, J.M. MAYER, B. PLAZONNET and R. GURNY
"Ocular tolerance of preservatives on the murine cornea" 
European Journal of Pharmaceutics and Biopharmaceutics, 47, 105-112 (1999)

A. ROTHEN-WEINHOLD, K. BESSEGHIR, E. VUARIDEL, E.SUBLET, N. OUDRY and R. GURNY
"Stability studies of a somatostatin analogue in biodegradable implants" 
International Journal of Pharmaceutics, 178 (2), 213-221 (1999)

R.H. GUY, J.J. HOSTYNEK, R.S. HINZ and C.R. LORENCE
"Metals and the skin - Topical effects and percutaneous absorption" 
(Eds), Marcel Dekker, New York, p.431 (1999) 

A.L. STINCHCOMB, F. PIROT, G.D. TOURAILLE, A.L. BUNGE and R. H. GUY
"Chemical uptake into human stratum corneum in vivo from volatile and non-volatile solvents" 
Pharmaceutical Research, 16 (8), 1288-1293 (1999) 

V. MERINO, A. LOPEZ, D. HOCHSTRASSER and R. H. GUY
"Noninvasive sampling of phenylalanine by reverse iontophoresis" 
Journal of Controlled Release, 61 (1-2), 65-69 (1999)

V. MERINO, A. LOPEZ, Y. N. KALIA and R. H. GUY
"Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil" 
Pharmaceutical Research, 16 (5), 758-761 (1999)

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Synthesis and characterization of self-catalyzed  poly(ortho esters) based on decanediol and decanediol-lactate" 
J. Biomat. Sci. Polym. Ed. 10 (3), 375-389 (1999)

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Hydrolysis and erosion studies of autocatalyzed poly(ortho esters) containing lactoyl-lactyl acid dimers" 
Macromolecules 32 (2), 301-307 (1999)

N. VIVIEN CASTIONI, P.C. BAEHNI and R. GURNY
"Current status in oral fluoride pharmacokinetics and implications for the prophylaxis against dental caries" 
European Journal of Pharmaceutics and Biopharmaceutics, 45, 101-111 (1998)

B. GREWAL, A. NAIK, W. J. IRWIN and J. A. BOUWSTRA
"Transdermal iontophoresis of dextrans: donor concentration effects and enhancer pretreatment on steady state flux" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA,  pp. 24-25. (1998)

B. GREWAL, A. NAIK and W. J. IRWIN
"Drug, vehicle and enhancer interactions in percutaneous transport: simultaneous analysis by ATR-IR spectroscopy" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA,  pp. 569-570 (1998)

A. LUZARDO-ALVAREZ, J. BLANCO-MENDEZ, R. H. GUY and M.B. DELGADO-CHARRO
"Characterization of the permselective properties of neonatal porcine skin" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 601-602  (1998)

M.B. DELGADO-CHARRO, Y.N. KALIA and R.H. GUY
"The relative contributions of electrorepulsion and electroosmosis to iontophoretic transport" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 599-600 (1998)

N.M. RANJHA and  E. DOELKER
"Solute release behavior from pH-sensitive acrylic hydrogels for colonic drug delivery" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 886-887, Las Vegas (USA), 1998

D. QUINTANAR-GUERRERO, E. ALLÉMANN, E. DOELKER and H. FESSI
"A new procedure for the preparation of nanocapsules" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 842-843, Las Vegas (USA), 1998

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Understandig of degradation mechanism of autocatalyzed poly(ortho esters) containing lactoyl-lactic dimers" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 713-714, Las Vegas (USA) 1998

D. QUINTANR-GUERRERO, E. ALLEMANN, H. FESSI and E. DOELKER
"Pseudolatex preparation by direct displacement of partially water-miscible solvents from a conventional emulsion" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 840-841, Las Vegas (USA) 1998

E. DOELKER
"Release mechanisms of ingredients from controlled delivery systems" 
Proceed. Int'l. Symp. Control. Rel. Bioact. Mater., 25, 303, Las Vegas (USA) 1998

R.H. GUY, V. MERINO and A. LOPEZ
"Noninvasive sampling of phenylalanine by reverse iontophoresis" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 543-544 (1998)

A. LOPEZ, V. MERINO, Y.N. KALIA and R.H. GUY
"Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA, pp. 597-598. (1998)

D. MARRO, Y.N. KALIA and R.H. GUY
"Effect of molecular structure on iontophoretic transport" 
Proceed. Int.'l Symp. Control. Rel. Bioact. Mater., 25, Las Vegas, USA,  pp. 77-78 (1998)

I. ALBERTI, Y.N. KALIA and R.H. GUY
"Effect of percutaneous penetration enhancers on human skin barrier function in vivo
Proceed. 2nd World Meeting APGI/APV, Paris, pp. 853-854 (1998)

R.H. GUY, Y.N. KALIA, M.B. DELGADO-CHARRO, V. MERINO, A. LOPEZ and D. MARRO
"Iontophoresis: electrorepulsion and electroosmosis" 
Proceed. 5th European Symposium on Controlled Drug Delivery, Noordwijk aan Zee (The Netherlands),pp. 45-47 (1998)

F . J. OTERO-ESPINAR, M.B. DELGADO-CHARRO, S. ANGUIANO-IGEA and J. BLANCO-MENDEZ
"Using a tensile test to study the bioadhesive and swelling properties of polymers" 
in: Data Acquisition and Measurement techniques 
A. Muñoz-Ruiz and H. Vromans (eds.). Interpharm Press, Buffalo Grove,  pp. 295-342 (1998) 

M.B. DELGADO-CHARRO and R.H. GUY
"Iontophoresis of peptides" 
in: Electronically Controlled Drug Delivery; 
B. Berner and S. M. Dinh (eds.). CRC Press, Boca Raton, pp. 129-157 (1998) 

J.J. HOSTYNEK, R.S. HINZ, C.R. LORENCE and R.H. GUY
"Human skin penetration by metal compounds" 
in: Dermal Absorption and Toxicity Assessment, 
M.S. Roberts and K.A. Walters (eds), Marcel Dekker, New York, pp. 647-668 (1998) 

R.H. GUY
"Iontophoresis - Recent developments" 
J. Pharm. Pharmacol. 50, 371-374 (1998)

Y.N. KALIA, F. PIROT, R.O. POTTS and R.H. GUY
"Ion mobility in human stratum corneum in vivo
Journal of Pharmaceutical Sciences, 87, 1508-1511 (1998)

M.B. DELGADO-CHARRO and R.H. GUY
"Percutaneous penetration and transdermal drug delivery" 
Progr. Dermatol., 32(4), 1-12 (1998)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, E. DOELKER and H. FESSI
"Preparation and characterization of nanocapsules from preformed polymers by a new process based on emulsification-diffusion technique" 
Pharmaceutical Research, 15 (7), 1056-1062 (1998)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, H. FESSI and E. DOELKER
"Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers" 
Drug Dev.Ind.Pharm. 24 (12), 1113-1128 (1998)

F. DELIE
"Evaluation of nano- and microparticle uptake by the gastrointestinal tract" 
Adv.Drug Del.Rev. 34, 221-233 (1998)

F. DELIE and W. RUBAS
Préface 
Adv.Drug Delivery Rev. 34(2,3), 121 (1998)

Y.N. KALIA, L.B. NONATO, C.H. LUND and R.H.GUY
"Development of skin barrier function in premature infants" 
The Journal of Investigative Dermatology, 111, 320-326 (1998)

A. LUZARDO-ALVAREZ, M. RODRIGUEZ-FERNANDEZ, J. BLANCO-MENDEZ, R.H. GUY and M.B. DELGADO-CHARRO
"Iontophoretic permselectivity of mammalian skin: characterization of hairless mouse and porcine membrane models" 
Pharmaceutical Research, 15 (7), 984-987 (1998)

N.G. TURNER, C. CULLANDER and R.H. GUY
"Determination of the pH gradient across the stratum corneum" 
J. Invest. Dermatol. Symp. Proc. 3, 110-113 (1998)

J. BARRA, F. LESCURE, F. FALSON-RIEG and E. DOELKER
"Can the organization of a binary mix be predicted from the surface energy, cohesion parameter and particle size of its components?" 
Pharmaceutical Research, 15, 1727-1736 (1998)

M.B. SINTZEL, K. SCHWACH-ABDELLAOUI, K. MÄDER, R. STÖSSER, J. HELLER, C. TABATABAY and R. GURNY
"Influence of irradiation sterilization on a semi-solid poly(ortho ester)" 
International Journal of Pharmaceutics, 175, 165-176 (1998)

M.B. SINTZEL, J. HELLER, S.Y. Ng, C. TABATABAY, K. SCHWACH-ABDELLAOUI and R. GURNY
" In vitro drug release from self-catalysed poly(ortho ester): Case study of 5-fluorouracil" 
Journal of Controlled Release, 55, 213-218 (1998)

N.G. TURNER  and R. GUY
"Visualization and quantitation of iontophoretic pathways using confocal microscopy" 
J. Invest. Dermatol. Symp. Proc. 3,  136-142 (1998)

L. LANGKJAER, J. BRANGE, G.M. GRODSKY and R.H. GUY
"Iontophoresis of monomeric insulin analogues in vitro : effects of insulin charge and skin pretreatment" 
Journal of Controlled Release, 51, 47-56 (1998)

E. ALLÉMANN, J.-C. LEROUX and R. GURNY
"Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics" 
Adv. Drug Deliv. Rev. 34, 171-189 (1998)

O. FELT, P. BURI and R. GURNY
"Chitosan: A unique polysaccharide for drug delivery" 
Drug Dev. Ind. Pharm. 24 (11), 979-993 (1998)

P. BUSTAMANTE, M. ANGELES PEÑA and J. BARRA
"Partial-solubility parameters of piroxicam and niflumic acid" 
International Journal of Pharmaceutics, 174, 141-150 (1998)

A. GANEM-QUINTANAR, D. QUINTANAR-GUERRERO, F. FALSON-RIEG and P. BURI
" Ex vivo oral mucosal permeation of lidocaine hydrochloride with sucrose fatty acid esters as absorption enhancers" 
International Journal of Pharmaceutics, 173, 203-210 (1998)

P. BUSTAMANTE, M. ANGELES PEÑA and J. BARRA
"Partial-solubility parameters of naproxen and sodium diclofenac" 
J. Pharm. Pharmacol. 50, 975-982 (1998)

F. VEUILLEZ, A. GANEM-QUINTANAR, J. DESHUSSES, F. FALSON-RIEG and P. BURI
"Comparison of the ex-vivo oral mucosal permeation of tryptophan-leucine (Trp-Leu) and its myristoyl derivative" 
International Journal of Pharmaceutics, 170, 85-91 (1998)

A. GANEM-QUINTANAR, Y. JACQUES, F. FALSON-RIEG and P. BURI
"Lipid extracting effect of ethanol on keratinized oral mucosa" 
Pharmaceutical Research, 15 (3), 495-498 (1998)

Y.N. KALIA, V. MERINO and R.H. GUY
"Transdermal drug delivery: clinical aspects" 
Dermatol. Clin. 16, 289-299 (1998)

A.A. DESHPANDE, J. HELLER and R. GURNY
"Bioerodible polymers for ocular drug delivery" 
Crit. Rev. Ther. Drug Carrier Syst. 15 (4), 381-420 (1998)

C. WITSCHI and E. DOELKER
"Peptide degradation during preparation and in vitro release  testing of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) microparticles" 
International Journal of Pharmaceutics, 171, 1-18 (1998).

V. BAEYENS, V. KALTSATOS, B. BOISRAME, M. FATHI, and R. GURNY
"Evaluation of soluble bioadhesive ophthalmic drug inserts (BODI â ) for prolonged release of gentamicin: lachrymal pharmacokinetics and ocular tolerance" 
J. Ocular Pharm. 14 (3), 263-272 (1998).

J. BARRA and E. DOELKER
"Instrumentation of an eccentric tablet press" 
  in : Data Acquisition and Measurement Techniques, A.Muñoz-Ruiz and H. Vromans, (Ed), chap. 8, Interpharm Press, Inc., Buffalo Grove, Illinois, 1998, pp.189-238

N. ROUGE, E. ALLÉMANN, M. GEX-FABRY, L. BALANT, E.T. COLE, P. BURI and E. DOELKER
"Comparative pharmacokinetic study of a floating multiple-unit capsule, a high-density multiple-unit capsule and an immediate-release tablet containing 25 mg atenolol" 
Pharm. Acta Helv. 73, 81-87 (1998)

A.-L. CORNAZ-GUDET and P. BURI
"A simple and rapid high-performance liquid chromatography method to quantify and evaluate the purity of nicotine in solution and in microspheres" 
S.T.P. Pharma Sci. 8 (2), 139-144 (1998)

A. MERKLI, C. TABATABAY, R. GURNY and J. HELLER
"Biodegradable polymers for the controlled release of ocular drugs" 
Prog. Polym. Sci. 23, 563-580 (1998)

M.B. SINTZEL, J. HELLER, S.Y. Ng, M.S. TAYLOR, C. TABATABAY and R. GURNY
"Synthesis and characterization of self-catalyzed poly(ortho ester)" 
Biomaterials 19, 791-800 (1998)

N.M. RANJHA and E. DOELKER
"Equilibrium and dynamic swelling behaviour of pH-sensitive acrylic hydrogels for colonic drug delivery" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 937-938

F. VEUILLEZ, A. GANEM-QUINTANAR, J. DESHUSSES, F. FALSON-RIEG and P. BURI
"Comparison of the ex vivo buccal mucosa permeation of tryptophan-leucine (TRP-LEU) and its lipophilic derivative" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 923-924

Y. JACQUES, A. GANEM-QUINTANAR, E. TEILLAUD and P. BURI
"Permeability of heat-separated buccal epithelium to fentanyl in solution" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 921-922

I. ALBERTI, Y.N. KALIA and R.H. GUY
"Effect of percutaneous penetration enhancers on human skin barrier function in vivo" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 853-854

J. BARRA, F. FALSON-RIEG, F. LESCURE and E. DOELKER
"Effect of particle size on the interaction of powders in binary mixes, correlation with surface energy and cohesion parameters" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 133-134

K. SCHWACH-ABDELLAOUI, J. HELLER and R. GURNY
"Synthesis and characterization of new bioerodible polymers designed for controlled drug release applications" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 275-276

A. ROTHEN-WEINHOLD, K. BESSEGHIR, E. VUARIDEL and R. GURNY
"Injection-moulding versus extrusion for the preparation of long-acting biodegradable implants" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 357-358

O. FELT, P. FURRER, J.M. MAYER, B. PLAZONNET, P. BURI and R. GURNY
"Topical use of chitosan in ophthalmology: tolerance assessment by confocal microscopy and precorneal retention evaluation by gamma scintigraphy" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 913-914

S. EINMAHL, M. ZIGNANI, V. BAEYENS, E. VARESIO, J.-L. VEUTHEY, J. HELLER, C. TABATABAY and R. GURNY
"A biodegradable polymer designed for concomitant delivery of dexamethasone and 5-fluorouracil to the eye" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 969-970

F. DE JAEGHERE, E. ALLÉMANN, F. KUBEL, B. GALLI, E. DOELKER and R. GURNY
"pH-sensitive microparticles as oral delivery systems for antiinfective agents of poor water solubility" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 559-560

V. BAEYENS, V. KALTSATOS, B. BOISRAMÉ, Ph. DRUET, J.-L. DAVOT and R. GURNY
"Clinical evaluation of bioadhesive ophthalmic drug inserts (Bodi) containing gentamicin for the treatment of external ophthalmic infection" 
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, 991-992

M. BERTON, E. ALLÉMANN, H. TÜRLER, R. WEIL, L. ZWILLENBERG and R. GURNY
Proceed. 2nd World Meeting APGI/APV, Paris, 1998, p. 1119-1120

E. ALLÉMANN , J.-C. LEROUX and R. GURNY
"Biodegradable nanoparticles of poly(lactic acid) and poly(lactic-co-glycolic acid) for parenteral administration"
in: Pharmaceutical Dosage Forms: Disperse Systems, vol. 3, H.A. Lieberman, M.M. Rieger and G.S. Banker (Ed.), Marcel Dekker, Inc., New York, Basel, Hong Kong, 1998, pp. 163-193

V. BAEYENS, V. KALTSATOS, B. BOISRAMÉ, E. VARESIO, J.-L. VEUTHEY, M. FATHI, L.P. BALANT, M. GEX-FABRY and R. GURNY
"Optimized release of dexamethasone and gentamicin from a soluble ocular insert for the treatment of external ophthalmic infections" 
Journal of Controlled Release, 52, 215-220 (1998)

A. ROTHEN-WEINHOLD, K. BESSEGHIR, Y. De ZELICOURT and R. GURNY
"Development and evaluation in vivo of a long-term delivery system for vapreotide, a somatostatin analogue" 
Journal of Controlled Release, 52, 205-213 (1998)

F. PIROT, E. BERARDESCA, Y.N. KALIA, M. SINGH, H.I. MAIBACH and R.H. GUY
"Stratum corneum thickness and apparent water diffusivity: facile and noninvasive quantitation in vivo
Pharmaceutical Research, 15 (3), 492-494 (1998)

C. WITSCHI and E. DOELKER
"Influence of the microencapsulation method and peptide loading on poly(lactic acid) and poly(lactic-co-glycolic acid) degradation during in vitro testing" 
Journal of Controlled Release, 51, 327-341 (1998)

M. ZIGNANI, S.F. BERNATCHEZ, T. Le MINH, C. TABATABAY,  J.M. ANDERSON and R. GURNY
"Subconjunctival biocompatibility of a viscous bioerodable poly(ortho ester)" 
J. Biomed. Mater Res. 39, 277-285 (1998)

D. QUINTANAR-GUERRERO, A. GANEM-QUINTANAR, E. ALLÉMANN, H. FESSI and E. DOELKER
"Influence of the stabilizer coating layer on the purification and freeze-drying of poly(D,L-lactic acid) nanoparticles prepared by an emulsion-diffusion technique" 
J. Microencapsul. 15(1), 107-119 (1998)

Y. JACQUES, T. NGUYEN-XUAN, E. IONESCU, G.P. RAVELLI, P. BURI, P. BAEHNI and R. GURNY
" In vivo evaluation of hydrophilic and hydrophobic mucoadhesive semi-solid formulations containing sucralfate and lidocaine for intraoral use" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 59-63 (1997)

V. BAEYENS, C. PERCICOT, M. ZIGNANI, A.A. DESHPANDE, V. KALTSATOS and R. GURNY
"Ocular drug delivery in veterinary medicine" 
Adv. Drug Del. Rev. 28, 335-361 (1997)

P. FURRER, J.M. MAYER and R. GURNY
"Confocal microscopy as a tool for the investigation of the anterior part of the eye" 
J. Ocular. Pharmacol. Ther. 13(6), 559-578 (1997)

E. ALLÉMANN, P. GRAVEL, J.-C. LEROUX, L. BALANT and R. GURNY
"Kinetics of blood component adsorption on poly(D,L-lactic acid) nanoparticles: evidence of complement C3 component involvement" 
J. Biomed. Mater Res. 37 (2), 229-234 (1997)

N. ROUGE, E.T. COLE, E. DOELKER and P. BURI
"Screening of potentially floating excipients for minitablets" 
S.T.P. Pharma Sci. 7, 386-392 (1997)

A. ROTHEN-WEINHOLD, K. BESSEGHIR and R. GURNY
"Analysis of the influence of polymer characteristics and core loading on the in vivo release of a somatostatin analogue" 
Eur. J. Pharm. Sci. 5, 303-313 (1997)

A.-F. RIME, D. MASSUELLE, F. KUBEL, H.-R. HAGEMANN and E. DOELKER
"Compressibility and compactibility of powdered polymers: poly(vinyl chloride) powders" 
European Journal of Pharmaceutics and Biopharmaceutics, 44, 315-322 (1997)

M.B. SINTZEL, S.Y. Ng, M.S. TAYLOR, J. HELLER, C. TABATABAY and R. GURNY
"Synthesis and characterization of ointment-like self-catalyzed poly(ortho ester)" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 909-910 (1997)

M. ZIGNANI, T. LE MINH, C. TABATABAY and R. GURNY
"Improved biocompatibility of a viscous bioerodable poly(ortho ester) by controlling the environmental pH" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 907-908 (1997)

N. VIVIEN-CASTIONI, R. GURNY, V. KALTSATOS and P. BAEHNI
"Prophylaxis of caries - in vivo evaluation of various oral fluoride containing preparations designed to optimize salivary concentrations" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 905-906 (1997)

F. DE JAEGHERE, E. ALLÉMANN, J.-C. LEROUX, W. STEVELS, P.J. DIJKSTRA, F. FEIJEN, E. DOELKER and R. GURNY
"PLA-PEG nanoparticles: preparation and cell interaction studies" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 831-832 (1997)

A. ROTHEN-WEINHOLD, K. BESSEGHIR and R. GURNY
"Development of a long-term delivery system for RC-160, a somatostatin analog" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 827-828 (1997)

M. BERTON, K. HOWARD, L. BENIMETSKAYA, E. ALLÉMANN, R. WEIL, L.O. ZWILLENBERG, C.A. STEIN and R. GURNY
"Uptake of oligonucleotide loaded nanoparticles in prostatic cancer cells and their intracellular localization" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 669-670 (1997)

V. BAEYENS, E. VARESIO, J.-L. VEUTHEY, V. KALTSATOS, B. BOISRAME, M. FATHI and R. GURNY
"Combined release of dexamethasone and gentamicin from an ocular insert for treatment of external ophthalmic infections" 
Proceed. Int.'l Symp. Controlled Release Bioact. Mater., 24, 143-144 (1997)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, H. FESSI and E. DOELKER
"Applications of the ion-pair concept to hydrophilic substances with special emphasis on peptides" 
Pharmaceutical Research, 14 (2), 119-127 (1997)

A. GANEM-QUINTANAR, Y.N. KALIA, F. FALSON-RIEG and P. BURI
"Mechanisms of oral permeation enhancement" 
International Journal of Pharmaceutics, 156, 127-142 (1997)

Y. JACQUES, C. STAUB, I. MARQUET, C. CREBASSA and P. BURI
"Human buccal absorption of codeine phosphate from a bioadhesive drug delivery device" 
S.T.P. Pharma Sci. 7, 289-294 (1997)

Y. JACQUES and P. BURI
"An investigation of the physical behaviour of moisture-activated mucoadhesive hydrogels upon contact with biological and non-biological substrates" 
Pharm. Acta Helv. 72, 225-232 (1997)

V. BAEYENS and R. GURNY
"Chemical and physical parameters of tears relevant for the design of ocular drug delivery formulations" 
Pharm. Acta Helv. 72 191-202 (1997)

M.B. SINTZEL, A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Synthesis and analysis of viscous poly (ortho-ester) analogs for controlled drug release" 
International Journal of Pharmaceutics, 155, 263-269 (1997)

M. ZIGNANI, A. MERKLI, M.B. SINTZEL, S.F. BERNATCHEZ, W. KLOETI, J. HELLER, C. TABATABAY and R. GURNY
"New generation of poly(ortho esters): synthesis, characterization, kinetics, sterilization and biocompatibility" 
Journal of Controlled Release, 48, 115-129 (1997)

A.A. DESHPANDE, C. TABATABAY, P.M. HUGHES and R. GURNY
"Therapeutic applications of retinoids in ophthalmology" 
International Journal of Pharmaceutics, 157, 1-15 (1997)

M.B. SINTZEL, A. MERKLI, C. TABATABAY and R. GURNY
"Influence of irradiation sterilization on polymers used as drug carriers - A review" 
Drug Dev. Ind. Pharm. 23, 857-878 (1997)

R.M. BRAND, P. SINGH, E. ASPE-CARRANZA, H.I. MAIBACH and R.H. GUY
"Acute effects of iontophoresis on human skin in vivo : cutaneous blood flow and transepidermal water loss measurements" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 133-138 (1997)

N.G. TURNER, L. FERRY, M. PRICE, C. CULLANDER and R.H. GUY
"Iontophoresis of poly-L-lysines: the role of molecular weight?" 
Pharmaceutical Research, 14 (10), 1322-1331 (1997)

A. A. DESHPANDE, N. H. SHAH, C.T. RHODES and W. MALICK
"Development of a novel controlled-release system for gastric retention" 
Pharmaceutical Research, 14 (6), 815-819 (1997)

A. GANEM-QUINTANAR, F. FALSON-RIEG and P. BURI
"Contribution of lipid components to the permeability barrier of oral mucosa" 
European Journal of Pharmaceutics and Biopharmaceutics, 44, 107-120 (1997)

N.G. TURNER and R.H. GUY
"Iontophoretic transport pathways: dependence on penetrant physicochemical properties" 
J. Pharm. Sci., 86 (12), 1385-1389 (1997)

J. HIRVONEN and R.H. GUY
"Iontophoretic delivery across the skin: electroosmosis and its modulation by drug substances" 
Pharmaceutical Research, 14 (9), 1258-1263 (1997)

M.B. DELGADO-CHARRO, G. IGLESIAS-VILAS, J. BLANCO-MENDEZ, A. LOPEZ.QUINTELA, J.P. MARTY and R.H. GUY
"Delivery of a hydrophilic solute through the skin from novel microemulsion systems" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 37-42 (1997)

E. ALLÉMANN, N. BRASSEUR, S.V. KUDREVICH, C. LA MADELEINE and J.E. VAN LIER
"Photodynamic activities and biodistribution of fluorinated zinc phthalocyanine derivatives in the murine EMT-6 tumour model" 
Int. J. Cancer 72, 289-294 (1997)

A.-L. CORNAZ-GUDET, A.F. GANEM QUINTANAR, and P. BURI
"Simple method of in vitro diffusion of nicotine across porcine palatine mucosa" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 259-264 (1997)

D. QUINTANAR-GUERRERO, E. ALLÉMANN, E. DOELKER and H. FESSI
"A mechanistic study of the formation of pollymer nanoparticles by the emulsification-diffusion technique" 
Colloid Polym. Sci. 275, 640-647 (1997)

V. MERINO, I. ALBERTI, Y.N. KALIA and R.H. GUY
"Transdermal and skin-targeted drug delivery" 
Journal of Cutaneous Medicine and Surgery, 2(2), 108-119 (1997)

V. MERINO, Y.N. KALIA and R.H. GUY
"Transdermal therapy and diagnosis by iontophoresis" 
Trends Biotechnol., 15, 288-290 (1997)

C. WITSCHI and E. DOELKER
"Residual solvents in pharmaceutical products: acceptable limits, influences on physicochemical properties, analytical methods and documented values" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 215-242 (1997)

J. BARRA, F. LESCURE, E. DOELKER and P. BUSTAMANTE
"The expanded Hansen approach to solubility parameters. Paracetamol and citric acid in individual solvents" 
J. Pharm. Pharmacol. 49, 644-651 (1997)

V. BAEYENS, E. VARESIO, J.-L. VEUTHEY and R. GURNY
"Determination of dexamethasone in tears by capillary electrophoresis" 
J. Chromatogr. B. 692, 222-226 (1997)

N.G. TURNER, Y.N. KALIA and R.H. GUY
"The effect of current on skin barrier function in vivo : recovery kinetics post-iontophoresis" 
Pharmaceutical Research, 14 (9), 1252-1257 (1997)

F. PIROT. Y.N. KALIA, A.L. STINCHCOMB, G. KEATING, A. BUNGE and R.H. GUY
"Characterization of the permeability barrier of human skin in vivo
Proceed. Natl. Acad. Sci. USA, 94, 1562-1567 (1997)

A. ROTHEN-WEINHOLD and R. GURNY
"Controlled and/or prolonged parenteral delivery of peptides from the hypothalamic pituitary axis" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 115-131 (1997)

J. BARRA, F. KUBEL and  E. DOELKER
"Polymorphism of paracetamol. New advances" 
Proceed. 3rd Symposium/workshops on pharmacy and thermal analysis, Switzerland, 2PO, 1997

Y.N. KALIA and R.H.GUY
"Interaction between penetration enhancers and iontophoresis: effect on human skin impedance in vivo
Journal of Controlled Release, 44, 33-42 (1997)

N. ROUGE, J.-C. LEROUX, E.T. COLE, E. DOELKER and P. BURI
"Prevention of the sticking tendency of floating minitablets filled into hard gelatin capsules" 
European Journal of Pharmaceutics and Biopharmaceutics, 43, 165-171 (1997)

A. GANEM-QUINTANAR, C. LAFFORGUE, F. FALSON-RIEG, P. BURI
"Evaluation of the transepidermal permeation of diethylene glycol monoethyl ether and skin water loss" 
International Journal of Pharmaceutics, 147, 165-171 (1997)

J. BARRA and R. SOMMA
"Influence of the physicochemical variability of magnesium stearate on its lubricant properties: possible solutions" 
Drug Dev. Ind. Pharm. 22, 1105-1120  (1996)

J. BARRA, F. LESCURE and E. DOELKER
"Influence of surface free energies and cohesion parameters on pharmaceutical  material interaction parameters - Theoretical simulations" 
Pharmaceutical Research, 13 (11), 1746-1751 (1996)

F. GURTLER, V. KALSATOS, B. BOISRAME and R. GURNY
"Development of a novel soluble ophthalmic insert: evaluation of ocular tolerance in rabbits" 
European Journal of Pharmaceutics and Biopharmaceutics, 42 (6), 393-398 (1996)

M.B. SINTZEL, S.F. BERNATCHEZ, C. TABATABAY and R. GURNY
"Biomaterials in ophthalmic drug delivery" 
European Journal of Pharmaceutics and Biopharmaceutics, 42, 358-374 (1996)

G. MESEGUER, P. BURI, B. PLAZONNET, A. ROZIER and R. GURNY
"Gamma scintigraphic comparison of eyedrops containing pilocarpine in healthy volunteers" 
J. Ocul. Pharmacol. Ther. 12, 481-488 (1996)

D. QUINTANAR-GUERRERO, H. FESSI, E. ALLÉMANN and E. DOELKER
"Influence of stabilizing agents and preparative variables on the formation of poly(D,L-lactic acid) nanoparticles by an emulsification-diffusion technique" 
International Journal of Pharmaceutics, 143, 133-141 (1996)

J.-C. LEROUX, E. ALLÉMANN, F. DE JAEGHERE, E. DOELKER and R. GURNY
"Biodegradable nanoparticles - From sustained release formulations to improved site specific drug delivery" 
Journal of Controlled Release, 39, 339-350 (1996)

N. ROUGE, P. BURI and E. DOELKER
"Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery" 
International Journal of Pharmaceutics, 136, 117-139 (1996)

E. ALLÉMANN, J. ROUSSEAU, N. BRASSEUR, S.V. KUDREVICH, K. LEWIS and J.E. VAN LIER 
"Photodynamic therapy of tumours with hexadecafluoro zinc phthalocyanine formulated in PEG-coated poly(lactic acid) nanoparticles" 
Int. J. Cancer 66, 821-824 (1996)

J.-C. LEROUX, E. DOELKER and R. GURNY
"The use of drug load nanoparticles in cancer chemotherapy" 
  in : MICROENCAPSULATION - Methods and industrial application, S. Benita, éd., Marcel Dekker, Inc., New York, Basel, Hong Kong, Chap. 16, 1996, pp. 535-575

V.H.L. LEE, H. YAMAHARA, R. GURNY, M.B. SINTZEL, M. MARTENET, M. GEX-FABRY, L. BALANT, S. OHDO and S.K. PODDER
"Basis for dosing time-dependent changes in the ocular and systemic absorption of topically applied timolol" 
J. Ocular Pharmacol. Ther. 12 (2), 103-113 (1996)

T. NGUYEN-XUAN, R. TOWART, A. TERRAS, Y. JACQUES, P. BURI and R. GURNY
"Mucoadhesive semi-solid formulations for intraoral use containing sucralfate" 
European Journal of Pharmaceutics and Biopharmaceutics, 42 (2), 133-137 (1996)

J. KRISTL, E. ALLÉMANN and R. GURNY
"Formulation and evaluation of zinc-phthalocyanine loaded poly(D,L-lactic acid) nanoparticles" 
Acta Pharm. 46, 1-12 (1996)

C. BITZ and E. DOELKER
"Influence of the preparation method on residual solvents in biodegradable microspheres" 
International Journal of Pharmaceutics, 131, 171-181 (1996)

A.-L. CORNAZ, A. DE ASCENTIS, P. COLOMBO and P. BURI
" In vitro characteristics of nicotine microspheres for transnasal delivery" 
International Journal of Pharmaceutics, 129, 175-183 (1996)

J. HIRVONEN, Y.N. KALIA and R.H. GUY
"Transdermal delivery of peptides by iontophoresis" 
Nature Biotechnology, 14, 1710-1713 (1996)

Y.N. KALIA, F. PIROT and R.H. GUY
"Homogeneous transport in a heterogeneous membrane: water diffusion across human stratum corneum in vivo
Biophysical Journal, 71, 2692-2700 (1996)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Purity and stability assessment of a semi-solid poly(ortho ester) used in drug delivery systems" 
Biomaterials 17, 897-902 (1996)

R.H. GUY, Y.N. KALIA, C.S. LIM, L.B. NONATO and N.G. TURNER
"Drug smuggling - creative ways to cross biological barriers" 
Chemistry in Britain. 32, 42-45 (1996)

Y.N. KALIA, L.B. NONATO and R.H. GUY
"The effect of iontophoresis on skin barrier integrity: Non-invasive evaluation by impedance spectroscopy and transepidermal water loss" 
Pharmaceutical Research, 13 (6), 957-961 (1996)

J.-C. LEROUX, R.M. COZENS, J.L. ROESEL, B. GALLI, E. DOELKER and R. GURNY
"pH-sensitive nanoparticles: an effective means to improve the oral delivery of HIV-1 protease inhibitors in dogs" 
Pharmaceutical Research, 13, 485-487 (1996)

A.-C. VIAL-BERNASCONI, P. BURI, E. DOELKER, E. BEYSSAC, G. DUCHAIX and J.-M. AIACHE
In vivo evaluation of an indomethacin monolithic, extended zero-order release hard-gelatin capsule formulation based on saturated polyglycolysed glycerides" 
Pharm. Acta Helv. 70, 307-313 (1995)

N. FOLLONIER, E. DOELKER and E.T. COLE
"Various ways of modulating the release of diltiazem hydrochloride from hot-melt extruded sustained release pellets prepared using polymeric materials" 
Journal of Controlled Release, 36, 243-250 (1995)

A. MERKLI, C. TABATABAY and R. GURNY
"Use of insoluble biodegradable polymers in ophthalmic systems for the sustained release of drugs" 
European Journal of Pharmaceutics and Biopharmaceutics, 41, 271-283 (1995)

J.-C. LEROUX, R. COZENS, J.L. ROESEL, B. GALLI, F. KUBEL, E. DOELKER and R. GURNY
"Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice" 
Journal of Pharmaceutical Sciences, 84 (12), 1387-1391 (1995)

F. GURTLER, V. KALTSATOS, B. BOISRAME, J. DELEFORGE, M. GEX-FABRY, L.P. BALANT and R. GURNY
"Ocular availability of Gentamicin in small animals after topical administration of a conventional eye drop solution and a novel long acting bioadhesive ophthalmic drug insert" 
Pharmaceutical Research, 12, 1791-1795 (1995)

M. ZIGNANI, C. TABATABAY and R. GURNY
"Topical semi-solid drug delivery: kinetics and tolerance of ophthalmic hydrogels" 
Adv. Drug Delivery Rev. 16, 51-60 (1995)

J.-C. LEROUX, F. DE JAEGHERE, B. ANNER, E. DOELKER and R. GURNY
"An investigation on the role of plasma and serum opsonins on the internalization of  biodegradable poly(D,L-lactic acid) nanoparticles by human monocytes" 
Life Sciences 57 (7), 695-703 (1995)

E. ALLÉMANN, N.BRASSEUR, O. BENREZZAK, J. ROUSSEAU, S.V. KUDREVICH, R.W. BOYLE, J.-C. LEROUX, R. GURNY and J.E. VAN LIER
"PEG-coated poly(lactic acid) nanoparticles for the delivery of hexadecafluoro zinc  phthalocyanine to EMT-6 mouse mammary tumours" 
J. Pharm. Pharmacol. 47, 382-387 (1995)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"The use of acidic and basic excipients in the release of 5-fluorouracil and mitomycin  C from a semi-solid bioerodible poly(ortho ester)" 
Journal of Controlled Release, 33, 415-421 (1995)

F. GURTLER, R. GURNY, V. KALTSATOS and B. BOISRAME
"Keeping the drug in your eye" 
CHEMTECH 25 (4), 33-34 (1995)

F. GURTLER, V. KALTSATOS, B. BOISRAME and R. GURNY
"Long-acting soluble Bioadhesive Ophthalmic Drug Insert (BODI) containing  gentamicin for veterinary use : optimization and clinical investigation" 
Journal of Controlled Release, 33, 231-236 (1995)

E. DOELKER, D. MASSUELLE, F. VEUILLEZ and P. HUMBERT-DROZ
"Morphological, packing, flow and tableting properties of new Avicel types" 
Drug Dev. Ind. Pharm. 21 (6), 643-661 (1995)

J.-C. LEROUX, E. ALLÉMANN, E. DOELKER and R. GURNY
"New approach for the preparation of nanoparticles by an emulsification-diffusion  method" 
European Journal of Pharmaceutics and Biopharmaceutics, 41, 14-18 (1995)

C. TABATABAY, S.F. BERNATCHEZ and R. GURNY
"Proceed with caution whenever using commercial 5-fluorouracil solution in glaucoma filtration surgery" 
Ocular Surgery News, International Edition, 5, 19 (1994)

E. DOELKER
"Assessment of powder compaction" 
in : Powder Technology and Pharmaceutical Processes, éd. D. Chulia, M. Deleuil and Y.Pourcelot, Elsevier, Amsterdam, chap. 13, 1994, pp 403-471

F. GURTLER and R. GURNY
"Patent literature review of ophthalmic inserts" 
Drug Dev. Ind. Pharm. 21 (1), 1-18 (1995)

M.B. DELGADO-CHARRO and R.H. GUY
"Characterization of convective solvent flow during iontophoresis" 
Pharmaceutical Research, 11 (7), 929-935 (1994)

F. LESCURE, R. GURNY and E. DOELKER
" In vitro and in vivo evaluation of progesterone implants based on new biodegradable  poly(glutamic and glutamate esters) copolymers" 
J. Biomater. Sci. Polymer Edn, 6, 797-807 (1994)

R. GURNY, S.F. BERNATCHEZ, A. MERKLI and C. TABATABAY
"New semi solid poly(ortho esters) designed for controlled drug delivery of injectable  products" 
B.T. Gattefossé 87, 63-66 (1994)

A.-L. CORNAZ and P. BURI
"Nasal mucosa as an absorption barrier" 
European Journal of Pharmaceutics and Biopharmaceutics, 40 (5), 261-270 (1994)

L.P. BALANT and E. DOELKER
"Metabilic considerations in prodrug design" 
in : Burger's Medical Chemistry and Drug Discovery, Fifth Edition, Vol. 1 : Principles and Practice, chapter 23, éd. M.E. Wolf, 1995, John Wiley & Sons, Inc.

G. MESEGUER, R. GURNY and P. BURI
" In vivo evaluation of dosage forms : application of gamma scintigraphy to non- enteral routes of administration" 
J. Drug Target. 2, 269-288 (1994)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Gamma sterilization of a semi-solid poly(ortho ester) designed for controlled drug  delivery - Validation and radiation effects" 
Pharmaceutical Research, 11, 1485-1491 (1994)

S. AFTABROUSHAD and E. DOELKER
"Factors influencing the entrapment of a water soluble model drug into injectable  microparticles prepared using solvent evaporation and phase separation techniques"
European Journal of Pharmaceutics and Biopharmaceutics, 40, 237-242 (1994)

N. VIVIEN, P. BURI, L. BALANT and S. LACROIX
"Nasal absorption of metoclopramide administered to man" 
European Journal of Pharmaceutics and Biopharmaceutics, 40, 228-231 (1994)

S. BERNATCHEZ, A. MERKLI, T. LE MINH, C. TABATABAY, J. ANDERSON and R. GURNY
"Biocompatibility of a new semisolid bioerodible poly(ortho ester) intended for the  ocular delivery of 5-fluorouracil" 
J. Biomed. Mat. Res., 28, 1037-1046 (1994)

G. MESEGUER, P. BURI and R. GURNY
"Application of medical imaging to pharmaceutical research : The example of gamma  scintigraphy. I. Technological aspects" 
European Journal of Pharmaceutics and Biopharmaceutics, 40, 111-121 (1994)

N. FOLLONIER, E. DOELKER and E.T. COLE
"Evaluation of hot-melt extrusion as a new technique for the production of polymer-based pellets for sustained release capsules containing high loadings of freely soluble  drugs" 
Drug Dev. Ind. Pharm. 20, 1323-1339 (1994)

S.F. BERNATCHEZ, C. TABATABAY and R. GURNY
"Sodium hyaluronate as a vehicle for an improved tolerance of 5-fluorouracil  administered subconjunctivally to rabbits" 
International Journal of Pharmaceutics, 106, 161-166 (1994)

J.-C. LEROUX, P. GRAVEL, L. BALANT, B. VOLET, B.M. ANNER, E. ALLÉMANN, E. DOELKER and R. GURNY
"Internalization of poly (D,L-lactic acid) nanoparticles by isolated human leukocytes  and analysis of plasma proteins adsorbed onto the particles" 
J. Biomed. Mat. Res., 28, 471-481 (1994)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Semi-solid hydrophobic bioerodible poly(ortho ester) for potential application in  glaucoma filtering surgery" 
Journal of Controlled Release, 29, 105-112 (1994)

E. ALLÉMANN, R. GURNY, E. DOELKER, F.S. SKINNER and H. SCHÜTZ
"Distribution, kinetics and elimination of radioactivitiy after intravenous and  intromuscular injection of 14C-savoxepine loaded poly (D,L-lactic acid) nanospheres  to rats" 
Journal of Controlled Release, 29, 97-104 (1994)

E. DOELKER, G. MESEGUER, A.-L. CORNAZ, H. LEUENBERGER, S. STRAUSAK and E. MELIK
"Pommade au stéarate" - Nouvelle formule, sans triéthanolamine" 
J.S.Ph. 132, 59-62 (1994)

E. ALLÉMANN, J.-C. LEROUX, R. GURNY and E. DOELKER
" In vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles  produced by  salting-out procedure" 
Pharmaceutical Research, 10, 1732-1737 (1993)

E. DOELKER
"Comparative compaction properties of various microcrystalline cellulose types and  generic products" 
Drug Dev. Ind. Pharm. 19, 2399-2471 (1993)

N. FOLLONIER and E. DOELKER
"Accelerated ageing test for predicting the short-term change of the mechanical  strength of compressed tablets" 
European Journal of Pharmaceutics and Biopharmaceutics, 39 (6), 267-268 (1993)

E. ALLÉMANN, R. GURNY, E. DOELKER
"Drug-loaded nanoparticles - Preparation methods and drug targeting issues" 
European Journal of Pharmaceutics and Biopharmaceutics, 39 (5), 173-191 (1993)

A. MERKLI, J. HELLER, C. TABATABAY and R. GURNY
"Synthesis and characterization of a new biodegradable semi-solid poly(ortho  ester) for drug delivery systems" 
J. Biomater. Sci. Polymer Edn, 4, 505-516 (1993)

G. MESEGUER, R. GURNY, P. BURI, A. ROZIER and B. PLAZONNET
"Gamma scintigraphic study of precorneal drainage and assessment of miotic response in rabbits of various ophthalmic formulations containing pilocarpine" 
International Journal of Pharmaceutics, 95, 229-234 (1993)

S.F. BERNATCHEZ, A. MERKLI, C. TABATABAY, R. GURNY, Q.H. ZHAO, J.M. ANDERSON and J. HELLER
"Biotolerance of a semisolid hydrophobic biodegradable poly(ortho ester) for  controlled drug delivery" 
J. Biomed. Mat. Res. 27, 677-681 (1993)

A.-F. RIME and E. DOELKER
"Caractéristiques de compression et comprimabilité des poudres de polymères à  usage pharmaceutique" 
S.T.P. Pharma Sciences 3 (2), 109-129 (1993)

E. DOELKER
"Cellulose Derivatives" 
in:  Advances in Polymer Sciences, Springer-Verlag, Berlin - Heidelberg, Vol. 107,  1993, pp 199-265

E. ALLÉMANN, E. DOELKER et R. GURNY
"Drug loaded poly(lactic acid) nanoparticles produced by a reversible salting-out  process : Purification of an injectable dosage form" 
European Journal of Pharmaceutics and Biopharmaceutics, 39, 13-18 (1993)

R. GURNY, C. TABATABAY, S.F. BERNATCHEZ, A. MERKLI, E. ALLÉMANN, C. AFTABROUCHAD, F. LESCURE and E. DOELKER
"Biodegradable polymers - Contemporary issues and new directions" 
Eur. J. Hosp. Pharm., 3, 15-19 (1993)

S.F. BERNATCHEZ, C. TABATABAY and R. GURNY
"Sodium hyaluronate 0.25% used as a vehicle increases the bioavailability of  topically administered gentamicin" 
Graefe's Arch. Clin. Exp. Ophthalmol. 231, 157-171 (1993)

Y. JACQUES and P. BURI
"Optimization of an ex vivo method for bioadhesion quantification" 
European Journal of Pharmaceutics and Biopharmaceutics, 38, 195-198 (1992)

S.F. BERNATCHEZ, O. CAMBER, C. TABATABAY and R. GURNY
"Use of hyaluronic acid in ocular therapy" 
in : Biopharmaceutics of Ocular Drug Delivery, P. Edman, ed., CRC Press, Boca Raton, Florida, Chap. 7 1993,pp 105-120

R. GURNY, H. IBRAHIM and P. BURI
"The development and use of in situ formed gels, triggered by pH" 
in : Biopharmaceutics of Ocular Drug Delivery, P. Edman, ed., CRC Press, Boca Raton, Florida, Chap. 5, 1993, pp 81-90

E. ALLÉMANN, R. GURNY and E. DOELKER
"Preparation of aqueous polymeric nanodispersions by a reversible salting-out  process : influence of process parameters on particle size" 
International Journal of Pharmaceutics, 87, 247-253 (1992)

H. IBRAHIM, C. BINDSCHAEDLER, E. DOELKER, P. BURI and R. GURNY
International Journal of Pharmaceutics, 87, 239-246 (1992)

F. LESCURE, R. GURNY, E. DOELKER and J.M. ANDERSON
"Long-term histopathological study of new polypeptidic biomaterials" 
Biomaterials 13 (14), 1009-1011 (1992)

C. AFTABROUCHAD and E. DOELKER
"Méthodes de préparation des microparticules biodégradables chargées en principes   actifs hydrosolubles" 
S.T.P. Pharma Sciences 2, 365-380 (1992)

Y. JACQUES and P. BURI
"Etude cinétique de l'hydratation de comprimes mucoadhesifs par mesure de la force de gonflement" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. Ill, 286-295, Paris (1992) 

C. AFTABROUCHAD and E. DOELKER
"Microparticules biodegradables chargées en principes actifs hydrosolubles : comparaison des méthodes de la séparation de phases et de l'évaporation du solvant" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. II, 213-222, Paris (1992)

N. FOLLONIER, E. DOELKER and E.T. COLE
"Optimization of the release of a highly dosed freely soluble drug from hot-melt extruded sustained release pellets prepared using polymeric materials" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. IV, 100-109, Paris (1992)

G. MESEGUER, R. GURNY, P. BURI, A. ROZIER and B. PLAZONNET
"Precorneal drainage of various pilocarpine-containing formulations assessed by gamma scintigraphy and comparison of residence time with prolongation of miotic response in rabbits" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. IV, 35-42, Paris (1992)

E. ALLEMANN, R. GURNY and E. DOELKER
"Preparation and optimization of nanoparticles by a reversible salting-out process avoiding surfactants" 
6e Congrès International de Technologie Pharmaceutique, APGI, Vol. Ill, 15-21, Paris (1992)

L. P. BALANT, A.E. BALANT-GORGIA, M. GEX-FABRY and M. EICHELBAUM
"Genetic polymorphisms in human drug metabolism" 
in: New Trends in Pharmacokinetics, A. Rescigno and A.K. Thakur, eds. Plenum Press, New York, 391 (1991)

N. FOLLONIER and E. DOELKER
"Biopharmaceutical comparison of oral multiple-unit and single-unit sustained-release dosage forms" 
S.T.P. Pharma Sciences 2, 141-158 (1992)

S. KOPP-KUBEL, C. BEYER,  E. GRAF, F. KUBEL and E. DOELKER
"Einfluss der Polymorphie von Phenobarbital auf Tabletteneigenschaften" 
European Journal of Pharmaceutics and Biopharmaceutics, 38, 17-25 (1992)

M.-P. DANDELOT KELLER, P. BURI and E. CHAROLLAIS
"Importance des lipases du tractus digestif pour l'hydrolyse des excipients lipidiques et l'enzymotherapie de substitution" 
- Deuxième partie Pharm. Acta Helv. 67, 66-68 (1992)

M.-P. DANDELOT KELLER, P. BURI and E. CHAROLLAIS
"Importance des lipases du tractus digestif pour l'hydrolyse des excipients lipidiques et l'enzymothérapie de substitution" 
- Première partie Pharm. Acta Helv. 67, 34-42 (1992)

L. P. BALANT, E. DOELKER and P. BURI
"Pharmacokinetic Strategies in the Development of Prodrugs" 
in: New Trends in Pharmacokinetics, A. Rescigno and A.K. Thakur, eds. Plenum Press, New York, 281 (1991)

H. IBRAHIM, C. BINDSCHAEDLER, E. DOELKER, P. BURI and R. GURNY
"Concept and development of ophthalmic pseudo-latexes triggered by pH"
Int. J. Pharm. 77, 211-219(1991)

E. DOELKER
"Nécessité de nouvelles voies et formes d 'administration pour les médicaments de nature peptidique - Innover pour réussir" 
J.S.Ph. 18, 490-495 (1991)

V. BELTRAMI, R. GURNY and E. DOELKER
"Comparative swelling behavior of crosslinked vinyl alcohol homo- and copolymers" 
18th Intern. Symp. Control. Rel. Bioact. Mater., Amsterdam (1991)

B. GANDER, F. KLOETI and P. CHRISTEN
"Stability of corticosteroids in zinc oxide- hydrophilic paste and lipophilic ointment" 
Eur. J. Pharm. Biopharm. 37, 64-68 (1991)

E. DOELKER
"Swelling behavior of water-soluble cellulose derivatives" 
in: Absorbent Polymer Technology (Studies in Polymer Science 8), eds;L. Brannon-Peppas and R.S. Harland, 125-145 , Elsevier, Amsterdam (1990)

A.-F. RIME, F. LESCURE, D. MORDIER, R. GURNY and E. DOELKER
"A new high performance data acquisition system interfacing an instrumented tablet machine to a microcomputer" 
Acta Pharm. Technol. 36, 264-268 (1990)

P. CHRISTEN, F. KLOETI and B. GANDER
Research and Reports "Stability of prednisolone and prednisolone acetate in various vehicles used in semi-solid topical preparations" 
J. Clin. Pharm. Thera.  15, 325-329  (1990)

R. GURNY, J. E. RYSER, C. TABATABAY, M. MARTENET, P. EDMAN and O. CAMBER
"Precorneal residence time in humans of sodium hyaluronate as measured by gamma scintigraphy" 
Graefe's Arch. Clin. Exp. Ophthalmol. 228, 510-512 (1990)

J. VONDERSCHER, P. BURI, J. DESHUSSES and H. SUCKER
"Absorption rate of drugs in rats - Application of the improved modified doluisio method to various classes of drugs" 
Acta Pharm. Technol. 36, 133-138 (1990)

L. P. BALANT, E. DOELKER and P. BURI
"Prodrugs for the improvement of drug absorption via different routes of administration" 
Eur. J. Drug Metab. Pharmacokinet. 15, 143-153 (1990)

V. BELTRAMI, R. GURNY and E. DOELKER
"Le poly(alcool) de vinyle dans les formes à libération prolongée destinées à la voie orale" 
Revue - Pharm. Acta Helv. 65, 130-142 (1990)

H. IBRAHIM, R. GURNY, P. BURI, J. GROVE, A. ROZIER and B. PLAZONNET
"Ocular bioavailability of pilocarpine from a phase transition latex system triggered by pH" 
Communication : 4e Congrès Européen de Biopharmacie et de Pharmacocinétique, Genève  (1990)

F. LESCURE, R. GURNY, E. DOELKER and D. BICHON
"Effect of various factors on the in vitro release of progesterone from a new class of implantable polypeptide" 
Communication : 4e Congrès Européen de Biopharmacie et de Pharmacocinétique, Genève (1990)

K.V. RANGA RAO, K. PADMALATHA DEVI and P. BURI
"Influence of molecular size and water solubility of the solute on its release from swelling and erosion controlled polymeric matrices" 
J. Control. Release, 12, 133-141 (1990)

S. KOPP-KUBEL, C. BEYER, E. GRAF and E. DOELKER
"Studien des Bruchverhaltens von Tabletten am Beispiel einer isotropen und einer anisotropen Model substanz" 
Acta Pharm. Technol. 36, 24-29 (1990)

P. WUTHRICH and P. BURI
"Intérêt de la voie transnasale pour l'administration des médicaments" 
Deuxième partie: "Modèles d 'étude de l'absorption nasale chez l'animal et paramètres susceptibles de l'influencer" 
Pharm. Acta Helv. 65, 2-13 (1990)

P. WUTHRICH and P. BURI
"Intérêt de la voie transnasale pour l'administration des médicaments" 
Première partie:  "Aspects de l'anatomie et de la physiologie nasale" 
Pharm. Acta Helv. 64, 322-331 (1989)

B. GANDER, V. BELTRAMI, R. GURNY and E. DOELKER
"Effects of the method of drug incorporation and the size of the monolith on drug release from cross-linked polymers" 
Int. J. Pharm. 58, 63-71 (1990)

E. DOELKER, D. MORDIER and S. KOPP
"Relevance of various mechanical strength measurements of pharmaceutical compressed tablets" 
in:  Powders and Grains - Proceedings of the International Conference on Micromechanics of Granular Media, J.Biarez and R. Gourves, eds, A.A. Balkema, Rotterdam, 411-416 (1989) 

F. LESCURE, R. GURNY, E. DOELKER, M. L. PELAPRAT, D. BICHON and J.M. ANDERSON
"Acute histopathological response to a new biodegradable polypeptidic polymer for implantable drug delivery system" 
J. Biomed. Mater. Res. 23, 1299-1313  (1989)

K.V. RANGA RAO and P. BURI
"A novel laboratory model for the film coating of microparticles" 
Acta Pharm. Technol. 35, 256-257 (1989)

B. GANDER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Effect of polymeric network structure on drug release from cross-linked poly(vinyl alcohol) micromatrices" 
Pharmaceutical Research 6, 578-584 (1989)

F. LESCURE, R. GURNY, E. DOELKER and J. AUGUSTYNSKI
"Utilisation du principe de l'iontophorèse ou de l'électrophorèse pour le contrôle de la libération de substances médicamenteuses " 
Pharm. Acta Helv. 64, 210-219 (1989)

K.V. RANGA RAO and P. BUR I
"A novel in situ method to test polymers and coated microparticles for bioadhesion" 
Int. J. Pharm. 52, 265-270  (1989)

R. DIEPOLD, J. KREUTER, J. HIMBER, R. GURNY, V.H.L. LEE, J.R. ROBINSON, M.F. SAETTONE and O.E. SCHNAUDIGL
"Comparison of different models for the testing of pilocarpine eyedrops using conventional eyedrops and a novel depot formulation (nanoparticles)" 
Graefe's Arch. Clin. Exp. Ophthalmol. 227, 188-193 (1989)

K.V. RANGA RAO, K. PADMALATHA DEVI and P. BURI
"Zero-order release of a very soluble drug from swelling and erosion controlled polymeric matrices" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. V, 242-249 (1989)

V. BELTRAMI, R. GURNY and E. DOELKER
"Matrices de poly(alcool de vinyle) à libération contrôlée, influence de l'inactivation de l'agent de réticulation sur les caractéristiques de gonflement, de chargement en principes actifs, et sur les profils de libération" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. V, 205-214 (1989) 

A.-F. RIME, F. LESCURE, D. MORDIER, R. GURNY and E. DOELKER
"Nouveau système d 'acquisition de données pour machine à comprimer instrumentée développée sur micro-ordinateur" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. IV, 425-432 (1989) 

M. P. DANDELOT KELLER, P. BURI and E. CHAROLLAIS
"Importance de la lipase gastrique sur la vitesse de libération in vitro d'une substance incorporée dans un excipient lipidique" 
Compte rendu 5e Congrès International de technologie pharmaceutique, APGI, Paris, Vol. IV, 126-133 (1989)

A. BEN-AMOR, E. DOELKER and P. BURI
"Augmentation de la biodisponibilité d'un agent hypolipémiant par incorporation dans une gélule à contenu liquide" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. Ill, 190-199 (1989)

C. KOLLER and P. BURI
"Libération in vitro de phenylephrine à partir de gels thermoreversibles" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. II, 112-121 (1989)

B. GANDER, R. GURNY and E. DOELKER
"Structural analysis of poly(vinyl alcohol) cross-linked by gamma irradiation in the presence of cosolutes, possibilities and limitations in formulation" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 261-267 (1989) 

B. GANDER and N. B. GRAHAM
"Monolayer adsoprtion of surfactants on drug crystals and its potential for modifying powder properties" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 251-260 (1989) 

E. DOELKER, D. MORDIER and F. KUBEL
"Possibilités d'erreur d 'interprétation des diagrammes d'analyse thermique des substances polymorphes, exemple du sulfabenzamide" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 222-231 (1989)

P. WUTHRICH, M. MARTENET and P. BURI
"Etude de la biodisponibilité du tetracosactide (AGTH1,24) après administration intranasale chez le rat" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 84-90 (1989)

H. IBRAHIM, R. GURNY, C. BINDSCHAEDLER and P. BURI
"Nouvelle technologie pour la préparation de systèmes médicamenteux microparticulaires à usage ophtalmique" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 70-76 (1989)

K .V. RANGA RAO, A. BEN-AMOR and P. BURI
"Studies on buccoadhesive tablet formulation of codeine phosphate" 
Compte rendu 5e Congrès International de Technologie Pharmaceutique, APGI, Paris, Vol. 1, 15-21 (1989)

S. KOPP, C. BEYER, E. GRAF, F. KUBEL and E. DOELKER
"Methodology for a better evaluation of the relation between mechanical strength of solids and polymorphic form" 
J. Pharm. Pharmacol. 41, 79-82  (1989)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Influence of emulsifiers on film formation from cellulose acetate latexes. 
II. Modeling approach to the fate of emulsifiers in highly plasticized films" 
J. Appl. Polym. Sci.  37,  173-182  (1989)

K.V. RANGA RAO, K. PADMALATHA DEVI and P. BURI
"Cellulose matrices for zero-order release of soluble drugs" 
Drug Dev. Ind. Pharm. 14, 2299-2320 (1988)

K. PADMA LATHA DEVI, K. V. RANGA RAO, S.K. BAVEJA, T. LEEMANN and P. DAYER
"Determination of alprenoloi and metoprolol in plasma by column liquid chromatography" 
J. Chromat. - Biomedical Applications - 434,  265-270  (1988)

S. KOPP, C. BEYER, E. GRAF, F. KUBEL and E. DOELKER
"McSgIiche Fehiinterpretationen bei Thermoanalyse-Diagrammen am Beispiel von polymorphem Phenobarbital" 
Acta Pharm. Technol. 34, 213-217 (1988)

K.V. RANGA RAO and K. PADMA LATHA DEVI 
"Swelling controlled-release systems : recent developments and applications" 
Int. J. Pharm. 48, 1-13  (1988)

K.V. RANGA RAO and P. BURI
"Studies on factors affecting the bioadhesion of coated microparticles " 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 103-104 (1988)

K.V. RANGA RAO, K. PADMALATHA DEVI, F. KUBEL and P. BURI
"Studies on factors affecting the release of drugs through cellulose matrices" 
Proceed. Intern. Symp. Control. Rel. Biocat. Mater. 15, 101-102 (1988)

F. LESCURE, R. GURNY, E. DOELKER and J. AUGUSTYNSKI
" In vitro evaluation of a new electrophoretically controlled drug delivery system based on a crosslinked gel" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 362-363 (1988)

J. KREUTER, R. DIEPOLD, G. ANDERMANN, R. GURNY, V. H. L. LEE, J. R. ROBINSON, M. F. SAETTONE and O. E. SCHNAUDIGEL
"Comparison of different in-vitro and in-vivo test-models for pilocarpine using conventional and depot eyedrops (nanoparticles)" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 203-204 (1988)

B. GANDER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Macromolecular network characteristics and their effect on drug release from cross-linked poly(vinyl alcohol) micromatrices " 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 109-110 (1988)

F. LESCURE, R. GURNY, E. DOELKER, M. L. PELAPRAT, D. BICHON and J. M. ANDERSON
"Evaluation of new poly(glutamic acid esters) from implantable drug delivery systems" Proceed, intern. Symp. Control. Rel. Bioact. Mater. 15, 107-108 (1988)

V. BELTRAMI, R. GURNY and E. DOELKER
"Drug loading conditions for highly dosed crosslinked PVA matrices with controlled release properties" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 15, 46-47 (1988)

E. DOELKER
"Recent advances in tableting science" 
Bollettino Chimico Farmaceutico 127, 37-49 (1988)

H. IBRAHIM, P. BURI and R. GURNY
"Composition, structure et paramètres physiologiques du système lacrymal impliqués dans la conception des formes ophtalmiques" 
Pharm. Acta Helv. 63, 146-154 (1988)

A. C. VIAL-BERNASCONI, E. DOELKER and P. BURI
"Gélules à libération prolongée : formes divisées et monolithiques" 
S.T.P. Pharma 4, 397-409 (1988)

E. DOELKER and A. C. VIAL-BERNASCONI
"Interactions contenant-contenu au sein des capsules gélatineuses et évaluation critique de leurs effets sur la disponibilité des principes actifs" 
S.T.P. Pharma 4, 298-306 (1988)

C. ROBERT, P. BURI and N. A. PEPPAS
"Experimental method for bioadhesive testing of various polymers " 
Acta Pharm. Technol. 34, 95-98 (1988)

T. NOOK, E. DOELKER and P. BURI
"Intestinal absorption kinetics of various model drugs in relation to partition coefficients" 
Int. J. Pharm., 43, 119-129 (1988)

J.-J. SCHAER, L. RECLARU and E. DOELKER
"Study of adsorption and desorption of drugs on solids by a dynamic method" 
Acta Pharm. Technol. 34, 32-37 (1988)

B. GANDER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Crosslinked poly(alkylene oxides) for the preparation of controlled release micromatrices" 
J. Control. Release 5, 271-283 (1988)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Influence of emulsifiers on film formation from cellulose acetate latexes. 
I. Experimental study of phase separation phenomena due to sodium sulfate" 
J. Appl. Polym. Sci.,  34,  2631-2647  (1987)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Osmotic wate;qtransport through cellulose acetate membranes produced from a latex system" 
J. Pharm. Sci.,  76,  455-460  (1987)

T. NOOK, E. DOELKER and P. BURI
"Rôle de la bile et des sels biliaires dans l'absorption des médicaments" 
Pharm. Acta Helv. 62, 274-281 (1987) 

C. BINDSCHAEDLER and N. A. PEPPAS
"Detachment of small axisymmetric particles from fluid-liquid interfaces" 
Chem. Engin. Sci. 42, 2531-2546 (1987)

C. GABUS-SANNIE and P. BURI
"Etude comparative des méthodes de détermination du volume d'eau absorbé lors de perfusion de l'intestin grêle du rat" 
S.T.P. Pharma 3, 856-860 (1987)

R. GURNY, H. IBRAHIM, A. AEBI, P. BURI, C.G. WILSON, N. WASHINGTON, P. EDMAN and O. CAMBER
"Design and evaluation of controlled release systems for the eye" 
J. Control. Release 6, 367-373 (1987) 

R. GURNY, H. IBRAHIM, T. BOYE and P. BURI
"Latices and thermosensitive gels as sustained delivery systems to the eye" 
in: Ophthalmic Drug Delivery. Biopharmaceutical, technological and clinical aspects, M.F. Saettone, M. Bucci and P. Speiser eds, Fidia Research Series, Liviana Press, Padova, Vol. II, pp 27-36 (1987)

E. DOELKER, R. GURNY, J. SCHURZ, A. JXNOSI and N. MATIN
"Degrees of crystallinity and polymerization of modified cellulose powders for direct tableting" 
Powder Technology 52, 207-213 (1987)

H. IBRAHIM, T. BOYE, M. WERMEILLE, R. GURNY and P. BURI

"Determination of pilocarpine by HPLC in presence of isopilocarpine and a pH-sensitive polymer in ophthalmic dispersions" 
J. Pharm. Biomed. Anal.,  5, 379-382  (1987)

E. DOELKER, D. MORDIER, H. ITEN and P. HUMBERT-DROZ
"Comparative tableting properties of sixteen microcrystalline celluloses" 
Drug Dev. Ind. Pharm. 13, 1847-1875 (1987)

T. NOOK, E. DOELKER and P. BURI
"Intestinal absorption of nine drugs from oily vehicles and its relation to partition phenomena" 
Acta Pharm. Technol. 33, 115-119 (1987)

C. ROBERT, P. BURI and N. A. PEPPAS
"Influence of the drug solubility and dissolution medium on the release from poly(2-hydrocyethylmethacrylate) microspheres" 
J. Control. Release 5, 151-157.(1987)

E. DOELKER
"Water-swollen cellulose derivatives in pharmacy" 
in: Hydrogels in Medicine and Pharmacy, N.A. Peppas ed., CRC Press, inc., Boca Raton, Florida, Vol. II, Chap. 5, pp 115-160 (1987)

O. CAMBER, P. EDMAN and R. GURNY
"Influence of sodium hyaluronate on the miotic effect of pilocarpine in rabbits" 
Current Eye Research 6(6), 779-784 (1987)

E. DOELKER
"Proposition de classification des polymères biocompatibles pour les formes médicamenteuses à libération contrôlée" 
S.T.P. Pharma 3, 207-215 (1987)

P. BURI
"Définition et classification des systèmes matriciels" 
S.T.P. Pharma 3, 193-199 (1987)

C. KOLLER and P. BURI
"Propriétés et intérêt pharmaceutique des gels thermo réversibles à base de poloxamers et poloxamines" 
S.T.P. Pharma 3, 115-124 (1987)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Mechanically strong films produced from cellulose acetate latexes" 
J. Pharm. Pharmacol. 39, 335-338  (1987)

F. GUMOWSKI, E. DOELKER and R. GURNY
"The use of a new redispersible aqueous enteric coating material" 
Pharm. Technol. 11(2), 26-32 (1987)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Osmotically controlled drug delivery systems produced from organic solutions and aqueous dispersions of cellulose acetate" 
J. Control. Release 4, 203-212 (1986) 

T. HARMIA, J. KREUTER, P. SPEISER, T. BOYE, R. GURNY and A. KUBIS
"Enhancement of the myotic response of rabbits with pilocarpine-loaded polybutylcyanoacrylate nanoparticles" 
Int. J. Pharm. 33, 187-193 (1986)

B. GANDER, R. GURNY and E. DOELKER
"Crosslinked poloxamers as a versatile monolithic drug delivery system" 
Drug Dev. Ind. Pharm. 12, 1613-1623 (1986)

C. ROBERT and P. BURI
"Le mucus et son rôle dans l'absorption des médicaments" 
Pharm. Acta Helv. 61, 210-214 (1986)

C. DOELKER, E. DOELKER, P. BURI and L. WAGINAIRE
"The incorporation and in vitro release profiles of liquid, deliquescent or unstable drugs with fusible excipients in hard gelatin capsules" 
Drug Dev. Ind. Pharm. 12, 1553-1565 (1986) 

P. BURI, A.C. VIAL-BERNASCONI and C. DOELKER
"Modulation de la cinétique et de la vitesse de libération par un choix adéquat de l'excipient : Exemple des Gélucire" 
B.T. Gattefossé. 78, 67-73 (1985)

E. DOELKER
"Systèmes matriciels et libération d'ordre zéro : Le rôle de l'excipient" 
B.T. Gattefossé. 78, 51-60 (1985)

B. GANDER, R. GURNY and E. DOELKER
"Matrices à libération contrôlée par le gonflement du polymère. 
Partie I : Mécanismes de pénétration des solvants dans les polymères" 
Pharm. Acta Helv. 61, 130-134 (1986)
Partie II : Préparation des systèmes médicamenteux et analyse de la cinétique de libération" 
Pharm. Acta Helv. 61, 178-184 (1986)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Processus de formation de films semi-perméables d 'acétate de cellulose à partir de solutions organiques et de dispersions aqueuses submicroscopiques, rôle du tensio-actif dans les phénomènes de séparation de phases" 
4e Congrès International de Technologie Pharmaceutique APGI, Vol V, 123-132, Paris (1986) 

R. GURNY, F. GUMOWSKY and E. DOELKER
"Enrobage entérique avec une nouvelle forme de latex redispersible d'acétophtalate de cellulose" 
4e Congrès International de Technologie Pharmaceutique APGI, Vol. V, 117-122, Paris (1986) 

H. IBRAHIM, R. GURNY and P. BURI
"Méthodologie pour le choix de solvants dans la fabrication de pseudo-latex à base d'acétophtalate de cellulose" 
4e Congrès International de Technologie Pharmaceutique APGI, Vol. IV, 282-290, Paris (1986)

N.A. PEPPAS and P. BURI
"Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues" 
J. Control. Release 2, 257-275 (1985)

C. BINDSCHAEDLER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Thermodynamics of swelling of polymer latex particles by a water-soluble solvent 
II. Experimental results on cellulose acetate latices" 
J. Colloid Sci. 108, 83-94  (1985)

C. BINDSCHAEDLER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Thermodynamics of swelling of polymer latex particles by a water-soluble solvent 
I. Theoretical considerations" 
J. Colloid Interface Sci. 108, 75-82  (1985) 

B. GANDER, K. VENTOURAS, R. GURNY and E. DOELKER
"In vitro dissolution medium with supramicellar surfactant concentration and its relevance for in vivo absorption" 
Int. J. Pharm. 27, 117-124 (1985)

R.GURNY, T. BOYE, H. IBRAHIM and P. BURI
"Recent developments in controlled drug delivery to the eye" 
Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 12, 300-301 (1985) 

R. GURNY, T. BOYE and H. IBRAHIM
"Ocular therapy with nanoparticulate systems for controlled drug delivery" 
J. Control. Release, 2, 353-361 (1985)

B. GANDER, R. GURNY and E. DOELKER
"Einfluss der Zerfallseigenschaften von Tabletten auf die Freigabe und Absorption einer quasi unloslichen Model lsubstanz" 
Acta Pharm. Techn. 31, 77-84 (1985)

H.K. CHAN and E. DOELKER
"Polymorphic transformation of some drugs under compression" 
Drug Dev. Ind. Pharm. II, 315-332 (1985)

C. BINDSCHAEDLER, R. GURNY, E. DOELKER and N.A. PEPPAS
"Equilibrium behaviour of polymer particles in ternary emulsion systems" 
Makromol. Chem., Rapid Commun. 6, 267-270 (1985) 

P. BURI
"Les nouvelles formes médicamenteuses" 
Les entretiens du Caria, p. 83 (1982/1983)

C. ROBERT and P. BURI
"Effect of degree of crosslinking on water transport in polymer microparticles" 
J. Appl. Polymer Sci. 30, 301-306  (1985)

P. BURI
"Formulation, caractéristiques et intérêt des formes galéniques orales à libération prolongée de type matrice" 
Boll. Chim. Farm. 123, 453-464 (1984)

R. GURNY, J.M. MEYER and N.A. PEPPAS
"Bioadhesive intraoral release systems: design, testing and analysis" 
Biomaterials 5, 336-340 (1984)

T. BOYE, R. GURNY and P. BURI
"Développement et évaluation d'un nouveau type de forme ophtalmique à libération prolongée" 
2e Congrès Européen de Biopharmacie et Pharmacocinetique Salamanca (avril 1984)

R. GURNY
"Bioadhesive intraoral Release Systems" 
in: Polymeric Biomaterials Proc. NATO Advanced Study institute on Biopolymers, 212-220, Izmir (1984)

R. GURNY
"Controlled Drug Delivery with Colloidal Polymeric Systems" 
in: Polymeric Biomaterials Proc. NATO Advanced Study institute on Biopolymers, 195-211, Izmir (1984)

N.A. PEPPAS, P.J. HANSEN and P. BURI
"A theory of molecular diffusion in the intestinal mucus" 
Int. J. Pharm. 20, 107-118 (1984)

P. BURI
"Mesure de la vitesse de dissolution pour l'amélioration et le contrôle de la qualité des médicaments" 
J. Pharm. & Biomed. Analysis 1, 393-402  (1983)

P. BURI and J. HUMBERT-DROZ
"Solubilisation de principes actifs insolubles par des constituants des sucs digestifs" 
Labo-Pharma - Probl. Tech. 32, 197-199 (1984)

R. GURNY
"Latex Systems" 
in : Topics in Pharmaceutical Sciences, 277-288  (1983)

E. DOELKER
"Developments in compression: Compressional tests as an aid in tablet formulation" 
in : Topics in Pharmaceutical Sciences, 371-385  (1983) 

R.W. KORSMEYER, R. GURNY, E. DOELKER, P. BURI and N.A. PEPPAS
"Mechanisms of Potassium Chloride Release from Compressed, Hydrophilic, Polymeric Matrices ; Effect of Entrapped Air" 
J. Pharm. Sci. 72, 1189-1191  (1983) 

P. HUMBERT-DROZ, R. GURNY, D. MORDIER and E. DOELKER
"Densification behaviour of drugs presenting availability problems" 
Int. J. Pharm. Tech. & Prod. Mfr. 4, 29-35 (1983)

C. BINDSCHAEDLER, R. GURNY and E. DOELKER
"Notions théoriques sur la formation des films obtenus à partir de microdispersions aqueuses et application à l'enrobage" 
Labo-Pharma - Probl. Tech. 31, 389-394 (1983)

R. GURNY, E. DOELKER, P. BURI, R.W. KORSMEYER and N.A. PEPPAS
"Nouvelles observations sur le mécanisme de libération d'un soluté à partir de polymères hydrophiles" 
3e Congrès International de Technologie Pharmaceutique APGI, Vol. II, 97-105, Paris, 1983

R.W. KORSMEYER, R. GURNY, E. DOELKER, P. BURI and N.A. PEPPAS
"Mechanisms of solute release from porous hydrophilic polymers" 
Int. J. Pharm. 15, 25-35 (1983)

P. HUMBERT-DROZ, D. MORDIER and E. DOELKER
"Densification Behaviour of Powder Mixtures" 
Acta Pharm. Techn. 29, 69-73 (1983)

N.A. PEPPAS and R. GURNY
"Relation entre la structure des polymères et la libération contrôlée de principes actifs" 
Pharm. Acta Helv. 58, 2-8 (1983)

J. CHEHADE, R. GURNY, E. DOELKER and P. BURI
"Aqueous Coating with the Laboratory Apparatus Hi-Coater® HCT-20 Mini" 
Acta Pharm. Techn. 28, 141-148 (1982)

R. GURNY and W. KLOETI
"A New Device for Measuring the Miotic Response to Drugs. 
1. Preliminary Communication" 
Pharm. Acta Helv. 57, 274-275  (1982)

C. BINDSCHAEDLER and R. GURNY
"Optimisation de formulations pharmaceutiques par la méthode du Simplex au moyen d'une calculatrice TX 59" 
Pharm. Acta Helv. 57, 251-255 (1982)

C. DOELKER and E. DOELKER
"Comprimés à libération prolongée : mécanisme prépondérant de libération d'un traceur à partir de matrices de glycérides totaux et partiels" 
Pharm. Acta Helv. 57, 189-192 (1982) 

P. HUMBERT-DROZ, D. MORDIER and E. DOELKER
"Méthode rapide de détermination du comportement à la compression pour des études de préformulation" 
Pharm. Acta Helv. 57, 136-143 (1982)

M. BOYMOND-GENOUD, G. EIDE-JURGENSEN, D. MORDIER, E. DOELKER and P. BURI
"Importance du mouillage dans le processus de libération des principes actifs hydrophobes incorporés dans des gélules 
II. Désagrégation, dissolution et biodisponibilité chez l'homme" 
J. Pharm. Belg. 37  (2), 135-140  (1982)

R. GURNY, E. DOELKER and N.A. PEPPAS
"Modelling of sustained release of water-soluble drugs from porous, hydrophobic polymers" 
Biomaterials 3, 27-32 (1982)

A. DOMMEYER, J. BOUCHERAT and P. BURI
"Relations entre les propriétés physico-chimiques du tolbutamide seul ou coprecipité avec la polyvinylpyrrolidone et ses caractéristiques de dissolution" 
Acta Pharm. Techn. 27, 205-210 (1981)

E. DOELKER, C. DOELKER and D. MORDIER
"Importance du mouillage dans le processus de libération des principes actifs hydrophobes incorporés dans des gélules. 
1. Diffusion du milieu dans la paroi et pénétration capillaire dans la poudre" 
J. Pharm. Belg. 36  (6), 404-411  (1981)

P. BURI, E. DOELKER and J. BOUCHERAT
"Dissolution in vitro : un critère d'évaluation des formes médicamenteuses à libération prolongée" 
Schweiz. RundschauMed. (PRAXIS) 70 (29), 1310-1313 (1981)

R. GURNY, W. KLOETI and P. BURI
"Développement d'un systeme électro-optique permettant la mesure continue du diametre pupillaire" 
Premier Congrès Europeen de Biopharmacie and Pharmacocinetique - Pharmacocinetique experimentale Vol. 2, 398-402, Clermont-Ferrand  (avril 1981)

E. DOELKER and P. BURI
"Formulation des comprimés à libération prolongée.  III. Matrices lipidiques" 
Pharm. Acta Helv. 56, 111-118 (1981)

R.  GURNY
"Preliminary Study of Prolonged Acting Drug Delivery System for the Treatment of Glaucoma. 
Pharm. Acta Helv. 56, 130-132 (1981) 

P. BURI, E. DOELKER and J. BOUCHERAT
"Comparative in vitro Evaluation of six Commercial Vincamine Prolonged-released Dosage Forms" 
J. Clin. Hosp. Pharm. 6, 101-105  (1981)

R. GURNY, G.S. BANKER and P. BURI
"Développement d'un injectable de testostérone à action prolongée à base de latex biodégradable" 
III Congreso Nacionali Congrès hispano-français de Biopharmacie et Pharmacocinétique Tome 2, 173-179, Barcelona (1979)

P. BURI
"Emploi des polymères pour la fabrication des matrices hydrophiles et insolubles" 
ALPI, Lille (1981)

P. BURI
"Préformulation : pKa et coefficient de partage" 
Labo-Pharma - Problèmes et Techniques 307, 181-186 (1981)

C. GARCIN-SALOMON, J. BOUCHERAT, C. CREVOISIER and P. BURI
"The influence of Sodium Taurocholate (TCNa) on the Absorption of Salicylic Acid from the Rat Small Intestine" 
Pharm. Acta Helv. 56, 78-81 (1981)

R. GURNY, N.A. PEPPAS, D.D. HARRINGTON, G.S. BANKER
"Development of Biodegradable and injectable Latices for Controlled Release of Potent Drugs" 
Drug. Dev. Ind. Pharm. 7, 1-25 (1981) 

C. BOYMOND, E. DOELKER and P. BURI
"Influence de la formulation et de la méthode de préparation sur les caractéristiques de structure, de pénétration capillaire et de libération des matrices à base d'éthylcellulose" 
Pharm. Acta Helv. 56, 26-30 (1981)

N.A. PEPPAS, R. GURNY, E. DOELKER and P. BURI
"Modelling of Drug Diffusion through Swellable Polymeric Systems" 
J. Membr. Sci 7,  241-253  (1980)

J.L. YAEGER, R. GURNY, M.A. GONZALEZ, R. SJOQVIST and G.S. BANKER
"Bioavailability Assessment of Polymer interacted Dectropropoxyphene from Rectal Dosage Forms" 
(1st communication : "Entrapment Procedure and Blood Assay of Dextropropoxyphene") 
Pharm. Ind. 42, 1141-1143 (1980)

E. DOELKER, R. GURNY and D. MORDIER
"Effect of the Type of Binder on the Work involved in the Compression of Granulations" 
Acta Pharm. Techn. 26, 155-158 (1980) 

P. BURI and E. DOELKER
"Formulation des comprimés à libération prolongée.  II.  Matrices hydrophiles" 
Pharm. Acta Helv. 55, 189-197 (1980)

J.-L. SALOMON and E. DOELKER
"Formulation des comprimés à libération prolongée. I. Matrices inertes" 
Pharm. Acta Helv. 55, 174-182 (1980)

P. BURI
"Progrès récents dans le domaine des formes ophtalmiques et de leur contrôle" 
(1980)

P. BURI and C. SANNIE
"Utilisation de systèmes lipidiques pour améliorer l'absorption de médicaments liposolubles" 
(1980)

P. BURI
"Les nouveaux systèmes thérapeutiques : intérêt, applications, perspectives" 
Médecine et Hygiène 38, 962-968 (1980)

R. GURNY, M.A. GONZALEZ, G.S. BANKER and D.O. KILDSIG
"The Determination of the Entrapment Efficiency for a Molecular Dispersion System" 
Drug Dev. Ind. Pharm. 5, 437-445 (1979)

R. GURNY, S.P. SIMMONS, G.S. BANKER, R. MEEKER and R.D. MYERS
"A New Biocompatible Drug Delivery System for Chronic implantation in Animal Brain" 
Pharm. Acta Helv. 54, 349-352 (1979)

M.-H. RUTZ-COUDRAY, J. GIUST and P. BURI
"Libération prolongée, par inclusion dans une matrice inerte, de la drotavérine coprécipitée" 
Pharm. Acta Helv. 54, 363-365 (1979)

M.-H. RUTZ-COUDRAY, L. BALANT and P. BURI
"Utilité de l'analyse compartimentale pour le développement de formes galéniques à libération prolongée: expériences avec la drotavérine chez l'homme" 
Pharm. Acta Helv. 54, 210-213 (1979)

C. GARCIN-SALOMON, E. DOELKER, C. CREVOISIER and P. BURI
"Interaction entre le taurocholate de sodium et deux dérives salicylés : comparaison des informations apportées par différentes techniques" 
(3e communication : "Dialyse dynamique" 
Pharm. Acta Helv. 54, 206-209 (1979)

J.-L. SALOMON, E. DOELKER and P. BURI
"Sustained Release of a Water-Soluble Drug from Hydrophilic Compressed Dosage Forms" 
Pharm. Ind. 41, 799-802 (1979)

J. GRUENBERG, D. CORAL, A.L. KNUPFER and J. DESHUSSES
"Interactions of liposomes with trypanosoma brucei plasma membrane" 
Biochem. Biophys. Res. Commun. 88, 1173-1179 (1979)

C. GARCIN-SALOMON, E. DOELKER, C. CREVOISIER and P. BURI
"Interaction entre le taurocholate de sodium et deux dérives salicylés : comparaison des informations apportées par différentes techniques" 
(2e communication : "Dialyse à l'équilibre") 
Pharma Acta Helv. 54, 160-163 (1979)

C. GARCIN-SALOMON, E. DOELKER, C. CREVOISIER and P. BURI
"Interaction entre le taurocholate de sodium et deux dérives salicylés : comparaison des informations apportées par différentes techniques" 
(lère communication : "Méthode des solubilités") 
Pharm. Acta Helv. 54, 157-159 (1979)

J.L. SALOMON, P. VUAGNAT, E. DOELKER and P. BURI
"Importance de la technologie et de la formulation pour le mécanisme de libération du chlorure de potassium contenu dans des matrices hydrophiles" 
(2e communication : Influence de la force de compression, de la granulométrie du traceur et de l'épaisseur du comprimé") 
Pharm. Acta Helv. 54, 86-89 (1979)

J.-L. SALOMON, E. DOELKER et P. BURI
"Importance de la technologie and de la formulation pour le mécanisme de libération du chlorure de potassium contenu dans des matrices hydrophiles" 
(lère communication :"Influence de la viscosité et du pourcentage de gélifiant") 
Pharm. Acta Helv. 54, 82-85 (1979)

K. VENTOURAS and P. BURI
"Rôle de l'acidification de matrices hydrophiles sur la libération de principes actifs peu solubles en milieu intestinal" 
Pharm. Acta Helv. 53, 314-320 (1978)

E. DOELKER
"Physique de la compression, intérêt et limite des machines instrumentées pour l'optimisation de la formulation" 
Pharm. Acta Helv. 53, 182-188 (1978) 

E. DOELKER
"Mécanismes de libération des principes actifs à partir de microcapsules à action prolongée" 
Labo-Pharma - Problèmes et Techniques 281, 915-922 (1978) 

K. VENTOURAS, A. de PERROT and P. BURI
"Les modèles hydrodynamiques multicompartimentaux dans la recherche et l'enseignement :  applications pratiques" 
Pharm. Acta Helv. 53, 147-155 (1978)

P. BURI and E. DOELKER
"Equivalences des médicaments" 
Médecine et Hygiène 36, 1008 (1978)

R. GURNY, M. BOYMOND-GENOUD and P. GUITARD
"Analyse par régression multiple de l'influence de la faille des particules et de la présence de lactose sur la dissolution de capsules gélatineuses de phénacetine et d'acétanilide" 
J. Pharm. Belg. 33  (1), 6-10  (1978)

R. GURNY, P. BURI, H. SUCKER; P. GUITARD and H. LEUENBERGER
"Réalisation et développement théorique de formes médicamenteuses à libération contrôlée par des films méthacryliques" 
(4e communication : "Etude par régression linéaire multiple de facteurs technologiques influençant la libération d'un principe actif à partir de microgranules enrobées par fluidisation") 
Pharm. Acta Helv. 52, 247-251 (1977)

R. GURNY, P. GUITARD, P. BURI and H. SUCKER
"Réalisation et développement théorique de formes médicamenteuses à libération contrôlée par des films méthacryliques" 
(3e communication : "Préparation et caractérisation de formes galéniques à libération contrôlée" 
Pharm. Acta Helv. 52, 182-187 (1977)

J.-L. SALOMON and E. DOELKER
"Porosité des comprimés, importance et méthodes de détermination" 
Labo-Pharma - Problèmes et Techniques 272, 51-56 (1978) 

P. BURI
"Les méthodes d 'évaluation de la vitesse de libération des principes actifs in vitro" 
Journal Suisse de Pharmacie 116, 55-62 (1978)

R. GURNY, P. BURI, H. SUCKER, P. GUITARD and H. LEUENBERGER
"Réalisation et développement de formes médicamenteuses à libération contrôlée par des films méthacryliques 
(2e communication :"Etude par analyse orthogonale des facteurs influençant le transport à travers un film plan") 
Pharm. Acta Helv. 52, 175-181 (1977)

R. GURNY, P. GUITARD, P. BURI and H. SUCKER
(3e communication : "Préparation et caractérisation de formes galéniques à libération contrôlée") 
Pharm. Acta Helv. 52, 182-187 (1977)

P. BURI and K. VENTOURAS
"Aspect nouveau de la libération contrôlée : Les médicaments-réservoirs" 
16e Colloque de Pharmacie Industrielle, Gand (1977)

A. SAUTTER, E. DOELKER, P. BURI and D. MORDIER
"Etude du transport de principes actifs incorporés dans des émulsions liquides de type huile dans eau" 
(3e partie  : "Influence de quelques paramètres de formulation") 
J. Pharm. Belg. 32, 379-387  (1977)

K. VENTOURAS, L. BALAND, C. REVILLARD and P. BURI
"Application de l 'analyse multicompartimentale à la pharmacocinétique de la vincamine chez l'homme" 
Pharm. Acta Helv. 52, 97-105 (1977)

L. BALANT, C. REVILLARD and K. VENTOURAS
"Absorption gastro-intestinale et analyse multicompartimentale sur ordinateurs" 
Pharm. Acta Helv. 52, 89-95 (1977)

K. VENTOURAS, J. BOUCHERAT and P. BURI
"Influence des facteurs technologiques sur la libération de la vincamine incorporée dans des matrices hydrophiles" 
Pharm. Acta Helv. 52, 119-123 (1977)

A. SAUTTER, E. DOELKER, P. BURI and D. MORDIER
"Etude du transport de principes actifs incorporés dans des émulsions liquides de type huile dans eau" 
(2e partie :"Modèles cinétiques et cellule de diffusion") 
J. Pharm. Belg. 32,  229-240  (1977)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthesized for Direct Batch Operations" 
(4th communication: "Comparative studies on the release of the substance in vitro during various technological processes" 
Pharm. Ind. 39 (5), 512-515 (1977)

E. DOELKER and E. SHOTTON
"The effect of some binding agents on the mechanical properties of granules and their compression characteristics 
J. Pharm. Pharmac. 29,  193-198  (1977)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthersized for Direct Batch Operation" 
(3rd communication : "Effect of the physical characteristics of an active substance on its conversion into a dosage form") 
Pharm. Ind. 39 (3), 281-284 (1977)

R. GURNY, P. GUITARD and P. BURI
"Bestimmung der Wasserdampfpermeabilitat von Methacrylatcopolymeren verschiedener Zusammensetzung" 
Acta Pharm. Techn. 23 (1), 29-38 (1977)

R. GURNY, D. MORDIER and P. BURI
"Réalisation et développement théorique de formes médicamenteuses à libération contrôlée par des films méthacryliques" 
(lère communication : "Fabrication et évaluation de films plans libres") 
Pharm. Acta Helv. 51, 383-390 (1976)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthesized for Direct Batch Operations" 
(2nd communication:Transformation of the physical characteristics of (+) -cyanidanol-3 ) 
Pharm. Ind. 38 (12), 1175-1178 (1976)

K. VENTOURAS, P. SCHULZ, E. DOELKER, J. BOUCHERAT and P. BURI
"Etude pharmacocinétique de la vincamine administrée par voie orale" 
Pharm. Acta Helv. 51, 334-342 (1976)

R. GURNY, C. REVILLARD and E. DOELKER
"Computation of the RRSW Distribution by the Maximum Likelihood Method for Drug Release from Solid Dosage Forms" 
Pharm. Ind. 38 (10), 913-914 (1976)

C. CREVOISIER
"Résorption percutanée" 
Journal Suisse de Pharmacie 114, 421-425 (1976)

P. BURI
"Aspect biopharmaceutique des médicaments à libération contrôlée" 
Journal Suisse de Pharmacie 114, 405-411 (1976)

M.H. RUTZ-COUDRAY, L. BALANT, C. REVILLARD, P. BURI and J. GIUST
"Pharmacocinétique de la drotaverine chez l'homme" 
Pharm. Acta Helv. 51, 258-263 (1976)

M.A. DERMANCI and P. BURI
"Technological Study of a Drug Synthesized for Direct Batch Operation" 
(1st communication : "Study of the Drying Characteristics of (+)-Catechin") 
Pharm. Ind. 38 (5), 484-488 (1976)

M. ROUILLER, R. GURNY and E. DOELKER
"Possibilités de production avec un appareil à lit fluidisé de laboratoire" 
Acta Pharm. Techn. 22 (1) 55-68 (1976)

K. VENTOURAS and P. BURI
"Libération in vitro du sulfate de lithium incorpore à des matrices hydrophiles" 
Pharm. Acta Helv. 51, 212-218 (1976)

C. CREVOISIER and P. BURI
"Facteurs physico-chimiques susceptibles d'influencer l'absorption gastro-intestinale après dissolution des principes actifs" 
Pharm. Acta Helv. 51, 193-202 (1976)

A. SAUTTER, E. DOELKER, P. BURI and D. MORDIER
"Etude du transport de principes actifs incorporés dans des émulsions liquides de type huile dans eau"
(lere partie :"Caractérisation et contrôle du modèle d'émulsions par le compteur de Coulter") 
J. Pharm. Belg. 31 (3), 287-294  (1976)

R. GURNY
"Perméabilité à la vapeur d'eau de polymères, sous forme de films libres, utilisés pour l'enrobage" 
Pharm. Acta Helv. 51, 1-10 (1976)

J. BARRELET, M. TSACOPOULOS et P. BURI
"Cornea preparation for in vitro biopharmaceutical evaluation of ophthalmic dosage forms" 
J. Pharm. Pharmac. 27,  919-922  (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes a travers des membranes artificielles et biologiques" 
(5e communication ; "Etude du transport in situ à travers l'intestin grêle du rat") 
Pharm. Acta Helv. 50, 231-236 (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes à travers des membranes artificielles et biologiques" 
(4e communication :"Etude du transport in vitro à travers la paroi intestinale du rat et étude critique de la méthode du sac eversé") 
Pharm. Acta Helv. 50, 192 (1975)

P. BURI and C. CREVOISIER
"Emploi et intérêt des membranes dans la recherche pharmaceutique" 
Ets Gattefossé, F-69800 St. Priest (France) Bulletin Technique N° 68, 3-11 (1973/1974)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes à travers des membranes artificielles et biologiques" 
(3e communication :"Etude du transport in vitro à travers des membranes liquides organiques dans un modèle à trois phases") 
Pharm. Acta Helv. 50, 159-164 (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes à  travers des membranes artificielles et biologiques" 
(2e communication "Etude du transport in vitro à travers des membranes lipidiques composées") 
Pharm. Acta Helv. 50, 103-108 (1975)

E. DOELKER and P. BURI
"Une technique récente en pharmacie galénique, le micro-encapsulage" 
Pharm. Acta Helv. 50, 73-87 (1975)

E. DOELKER, H. SCHWYTER and D. MORDIER
"Evaluation biopharmaceutique de quelques comprimés d'acide acétylsalicylique. - Importance de la méthode de dissolution dans l'établissement de corrélations in vivo - in vitro
Pharm. Acta Helv. 50, 24-27 (1975)

C. CREVOISIER, P. BURI and J. BOUCHERAT
"Etude du transport de trois flavonoïdes  à travers des membranes artificielles et biologiques" 
(lere communication : "Etude du transport in vitro à travers des membranes de cellophane") 
Pharm. Acta Helv. 49, 140-151 (1974)

M. ROUILLER, R. GURNY and E. DOELKER
"Possibilités de production avec un appareil à lit fluidisé de laboratoire" 
Acta Pharm. Techn. 21 (2), 129-138 (1975)

K. VENTOURAS, P. DICK and P. BURI
"Etude d'une nouvelle forme galénique à action prolongée de sulfate de lithium" 
Journal Suisse de Médecine 103 (24), 878-881 (1973)

G.  JURGENSEN-EIDE
"Influence of complex formation on drug release from tablets" 
Acta Pharm. Suec. 10, 229-246 (1973)

E.  DOELKER and P.  BURI
"Etude de la libération in vitro d'une amine salifiée par un polyélectrolyte hydrosoluble" 
(3e communication : "Comparaison avec d'autres types de gels et considérations sur le mécanisme de libération") 
Pharm. Acta Helv. 48, 287-296 (1973)

E.  DOELKER and P.  BURI
"Etude de la libération in vitro d'une amine salifiée par un polyélectrolyte hydrosoluble" 
(2e communication "Facteurs susceptibles d'influencer la vitesse de libération") 
Pharm. Acta Helv. 48, 166-180 (1973)

E.  DOELKER and P. BURI
"Etude de la libération in vitro d'une amine salifiée par un polyélectrolyte hydrosoluble" 
(1ère communication : "Vue actuelle du problème et mise au point d'un test in vitro") 
Pharm. Acta Helv. 47, 495-507 (1972)

P.  BURI 
"Biopharmacie et développement d'un médicament" 
Médecine et Pharmacie, numéro spécial 5, 740-746 (1971)

E. DOELKER and P. BURI
"Quelques aspects biopharmaceutiques des comprimés pour la voie orale"
Médecine et Pharmacie, numéro spécial 5, 748-767 (1971)

E. DOELKER and P. BURI
"La chimiothérapie du cancer"
Journal Suisse de Pharmacie 107, 8, 31, 56 (1969)

P. BURI
"Le pharmacien suisse à l'Université"
Journal Suisse de Pharmacie 106, 442 (1968)

P.A. NUSSBAUMER, P. BURI and M. GENEQUAND
"Cholagogues et cholérétiques"
Journal Suisse de Pharmacie 106, 798, 830, 900, 930 (1968)