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Publications of 2008

Asso V, E. Ghilardi, S. Bertini, M. Digiacomo, C. Granchi, F. Minutolo, S. Rapposelli, A. Bortolato, S. Moro, M. Macchia (2008). alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors. ChemMedChem. 3, 1530-1534

Bisson, W., G. Westera, P.A. Schubiger and L. Scapozza (2008). Homology Modeling, Dynamics of Rat and Human Extracellular Domain of α4β2 and α7 Neuronal Nicotinic Acetylcholine Receptor Subtypes Journal of Molecular Modeling 14(10):891-9.

Bolognesi, M. L., F. Lizzi, R. Perozzo, R. Brun, A. Cavalli (2008). Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity. Bioorg Med Chem Lett 18(7): 2272-6.

Bortolato, A., G. Cozza, S. Moro (2008). Protein kinase CK2 inhibitors: emerging anticancer therapeutic agents? Anticancer Agents Med Chem 8(7): 798-806.

Bortolato A, S. Moro (2008). Designing a ligand for pharmaceutical purposes. Expert Opin. Drug Descov. 3, 579-590.

Chilin, A., R. Battistutta, A. Bortolato, G. Cozza, S. Zanatta, G. Poletto, M. Mazzorana, G. Zagotto, E. Uriarte, A. Guiotto, L. A. Pinna, F. Meggio, S. Moro (2008). Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships. J Med Chem 51(4): 752-9.

Conus, S., R. Perozzo, T. Reinheckel, C. Peters, L. Scapozza, S. Yousefi, H.-U. Simon (2008). Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. J Exp Med, 205:685-698.

Forconi, F., G. Poretti, I. Kwee, E. Sozzi, D. Rossi, P. M. Rancoita, D. Capello, A. Rinaldi, E. Zucca, D. Raspadori, V. Spina, F. Lauria, G. Gaidano, F. Bertoni (2008). High density genome-wide DNA profiling reveals a remarkably stable profile in hairy cell leukaemia. Br J Haematol 141(5): 622-30.

Forconi, F., A. Rinaldi, I. Kwee, E. Sozzi, D. Raspadori, P. M. Rancoita, M. Scandurra, D. Rossi, C. Deambrogi, D. Capello, E. Zucca, D. Marconi, R. Bomben, V. Gattei, F. Lauria, G. Gaidano, F. Bertoni (2008). Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with 17p deletion. Br J Hematol. 143(4):532-6.

Giddens, A.C., L. Nielsen, H.I. Boshoff, D. Tasdemir, R. Perozzo, M. Kaiser, F. Wang, J.C. Sacchettini, B.R. Copp (2008). Natural Product Inhibitors of Fatty Acid Biosynthesis: Synthesis of the Marine Microbial Metabolites Pseudopyronines A and B and Evaluation of their Anti-infective Activities. Tetrahedron 64:1242-1249.

Karioti, A., H. Skaltsa, X. Zhang, P. J. Tonge, R. Perozzo, M. Kaiser, S. G. Franzblau, D. Tasdemir (2008). Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata. Phytomedicine 15(12): 1125-9.

Morris, K. V., S. Santoso, A. M. Turner, C. Pastori, P. G. Hawkins (2008). Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet 4(11): e1000258.

Puttini, M., S. Redaelli, L. Moretti, S. Brussolo, R. H. Gunby, L. Mologni, E. Marchesi, L. Cleris, A. Donella-Deana, P. Drueckes, E. Sala, V. Lucchini, M. Kubbutat, F. Formelli, A. Zambon, L. Scapozza, C. Gambacorti-Passerini (2008). Characterization of compound 584, an Abl kinase inhibitor with lasting effects.Haematologica 93(5): 653-61.

Tartari, C. J., R. H. Gunby, A. M. L. Coluccia, R. Sottocornola, B. Cimbro, L. Scapozza, A. Donella-Deana, L. A. Pinna, C. Gambacorti-Passerini (2008). Characterization of some molecular mechanisms governing autoactivation of catalytic domain of the anaplastic lymphoma kinase J. Biol. Chem. 283(7):3743-50.