Publications of 2011

Bisson, W.H., S. Sengupta, L.K. Mathew, R.L. Tanguay. Alternate ligand binding structure influence regenerative outcome in an in vivo model of tissue regeneration. Submitted.

Benninghoff, A.D., W.H. Bisson, D. Koch, D.J. Ehresman, S.K. Kolluri, D. Williams (2011). Estrogen-like activity of perfluoroalkyl acids in vivo and interactions with human and rainbow trout estrogen receptor in vitro. Toxicol. Sci. 120, 42-58.

Boije Af Gennäs, G., L. Mologni, S. Ahmed, M. Rajaratnam, O. Marin, N. Lindholm, M. Viltadi, C. Gambacorti-Passerini, L. Scapozza, J. Yli-Kauhaluoma (2011). Design, Synthesis, and Biological Activity of Urea Derivatives as Anaplastic Lymphoma Kinase Inhibitors. ChemMedChem. doi: 10.1002/cmdc.201100168. [Epub ahead of print]

Campos-Olivas, R., M. Marenchino, L. Scapozza, F.L. Gervasio (2011). Backbone assignment of the tyrosine kinase Src catalytic domain in complex with imatinib. Biomol NMR Assign. [Epub ahead of print]

Chavez, J., J. Wu, W.H. Bisson, C. Maier. Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction. (in press J. Proteomics)

Chigrinova, E., M. Mian, M. Scandurra, T.C. Greiner, W.C. Chan, J.M. Vose, G. Inghirami, A. Chiappella, L. Baldini, M. Ponzoni, A.J. Ferreri, S. Franceschetti, G. Gaidano, A. Tucci, F. Facchetti, T. Lazure, O. Lambotte, S. Montes-Moreno, M.A. Piris, J.F. Nomdedeu, S. Uccella, P.M. Rancoita, I. Kwee, E. Zucca, F. Bertoni (2011). Diffuse large B-cell lymphoma with concordant bone marrow involvement has peculiar genomic profile and poor clinical outcome. Hematol Oncol. 29(1):38-41. doi: 10.1002/hon.953.

Cristiani, A., N. Brisotto, F.C. Cedrati, M. Floris, L. Scapozza, S. Moro (2011). ClickMD: an intuitive web-oriented molecular dynamics platform. Future Med Chem. 3(8):923-31.

Cristiani, A., G. Costa, G. Cozza, F. Meggio, L. Scapozza, S. Moro (2011). The Role of the N-Terminal Domain in the Regulation of the "Constitutively Active" Conformation of Protein Kinase CK2α: Insight from a Molecular Dynamics Investigation. ChemMedChem. 6(7):1207-16. doi: 10.1002/cmdc.201100046. [Epub ahead of print]

Dubey, S., R. Perozzo, L. Scapozza, Y.N. Kalia (2011). Noninvasive Transdermal Iontophoretic Delivery of Biologically Active Human Basic Fibroblast Growth Factor. Mol Pharm. Jul 5. [Epub ahead of print]

Goodale, B.C., J.K. La Du, W.H. Bisson, D.B. Janszen, K.M. Waters, R.L. Tanguay. Functional diversity of Aryl Hydrocarbon Receptors in zebrafish. Submitted.

Gurny, R., L. Scapozza, Y. Westermaier, M. Veurink (2011). Stabilized antibody preparations and uses thereof. WO2011 121559 A2.

Gurny, R., L. Scapozza, Y. Westermaier, M. Veurink (2011). Stabilized antibody preparations and uses thereof. WO2011 121560 A2.

Kristafor, S., I. Novakovic, T. Gazivoda Kraljevic, S. Kraljevic Pavelic, P. Lucin, L. Pernot, Y. Westermaier, L. Scapozza, S. M. Ametamey and S. Raic-Malic (2011): A new N-methyl thymine derivative comprising a dihydroxyisobutenyl unit as ligand for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK). Bioorg Med Chem Lett. 21, 6161-6165.

Kuettel, S., J. Greenwald, D. Kostrewa, S. Ahmed, L. Scapozza, R. Perozzo (2011). Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation. PLoS Negl Trop Dis. 5(5):e1164.

Jaquet, V., J. Marcoux, E. Forest, K.G. Leidal, S. McCormick, Y. Westermaier, R. Perozzo, O. Plastre, L. Fioraso-Cartier, B. Diebold, L. Scapozza, W.M. Nauseef, F. Fieschi, K.H. Krause, K. Bedard (2011). NOX NADPH oxidase isoforms are inhibited by celastrol with a dual mode of action. Br J Pharmacol. 164, 507-520.

Martic, M., L. Pernot, Y. Westermaier, R. Perozzo, T.G. Kraljevic, S. Kristafor, S. Raic-Malic, L. Scapozza, S. Ametamey (2011). Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo. Nucleosides Nucleotides Nucleic Acids. 30(4):293-315.

Mian, M., M. Scandurra, E. Chigrinova, Y. Shen, G. Inghirami, T.C. Greiner, W.C. Chan, J.M. Vose, M. Testoni, A. Chiappella, L. Baldini, M. Ponzoni, A.J. Ferreri, S. Franceschetti, G. Gaidano, S. Montes-Moreno, M.A. Piris, F. Facchetti, A. Tucci, J.F. Nomdedeu, T. Lazure, S. Uccella, M.G. Tibiletti, E. Zucca, I. Kwee, F. Bertoni (2011). Clinical and molecular characterization of diffuse large B-cell lymphomas with 13q14.3 deletion. Ann Oncol. Jun 21. [Epub ahead of print]

Murray, I.A., Flaveny, C.A., Chairo, C.R., Sharma, A.K., Tanos, R.S., Schroder, J.S., S. Amin, W.H. Bisson, S.K. Kolluri, G.H. Perdew (2011). Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-alpha-naphthoflavone. Mol. Pharmacology 79, 508-519.

Smith, K.J., I.A. Murray, R.S. Tanos, J. Tellew, A.E. Boitano, W.H. Bisson, S.K. Kolluri, M.P. Cooke, G.H. Perdew (2011). Identification of a high affinity ligand that exhibits complete Ah receptor antagonism. J Pharmacol Exp Ther. 338, 318-27.

Tartari, C.J., L. Scapozza, C. Gambacorti-Passerini (2011). The ALK Gene, an Attractive Target for Inhibitor Development. Curr Top Med Chem. 11(11):1406-19.

Veurink, M., C. Stella, C. Tabatabay, C.J. Pournaras, R. Gurny (2011). Association of ranibizumab (Lucentis®) or bevacizumab (Avastin®) with dexamethasone and triamcinolone acetonide: an in vitro stability assessment. Eur J Pharm Biopharm. 78(2):271-7.