Prof. David Rudrauf

Associate professor / Lab director

Campus Biotech - H8 - Room 02.150.157
+41 (0)22 379 59 69


computational modelling emotion artificial intelligence perspective taking spatial projection virtual reality embodied consciousness signal processing


David Rudrauf is an Associate Professor of Psychology at the University of Geneva (2016-present) and is currently the Director of the Laboratory of Multimodal Modelling of Emotion & Feeling (Swiss Center for Affective Sciences). Current research focuses on the development of computational models of normal and pathological psychology combined with virtual reality.

David Rudrauf obtained a master degree (2000) and a Ph.D. (2005) in Cognitive Sciences from Pierre and Marie Curie University, a Ph.D. in Neurosciences from the University of Iowa (2005), and a Habilitation from the University Joseph Fourier in Grenoble (2015). The author has worked as: Assistant Professor of Neurology & Radiology, in the Department of Neurology (University of Iowa; 2008–2011); non-permanent research scientist at the Laboratoire d'Imagerie Fonctionelle (INSERM, UMR S 678; 2012–2014); non-permanent research scientist at the Grenoble Institute of Neuroscience GIN (INSERM; 2014–2016); Director of the Laboratory of Brain Imaging and Cognitive Neuroscience, Division of Behavioral Neurology and Cognitive Neuroscience, Department of Neurology, (UIHC, University of Iowa; 2008–2011).



Book chapters


Rudrauf D, Samson, AC, Debbané M. (accepted) The relevance of artificial agent modelling for understanding how social feedback can affect emotional development: perspectives for psychological science. Handbook of Emotional Development (Eds. Samson A.,  Duke D., Walle E.), Oxford University Press.


Journal articles


Ognibene D, Giglia G, Marchegiani L, Rudrauf D. (2019) Implicit perceptiAjouter 

on simplicity

and explicit perception complexity in sensorimotor communication: Comment on "The

body talks: Sensorimotor communication and its brain and kinematic signatures" by

G. Pezzulo et al. Phys Life Rev. 2019 Mar;28:36-38. doi:

10.1016/j.plrev.2019.01.017. Epub 2019 Jan 30. PubMed PMID: 30770199.


Rudrauf D, Debbané M. (2018) Building a Cybernetic Model of Psychopathology: Beyond the Metaphor, Psychological Inquiry, 29:3, 156-164, DOI: 10.1080/1047840X.2018.1513685


Williford K, Bennequin D, Friston K, Rudrauf D. (2018) The Projective Consciousness

Model and Phenomenal Selfhood. Front Psychol. 2018 Dec 17;9:2571. doi:

10.3389/fpsyg.2018.02571. eCollection 2018. PubMed PMID: 30618988; PubMed Central

PMCID: PMC6304424.


Trebaul L, Deman P, Tuyisenge V, Jedynak M, Hugues E, Rudrauf D, Bhattacharjee

M, Tadel F, Chanteloup-Foret B, Saubat C, Reyes Mejia GC, Adam C, Nica A, Pail M,

Dubeau F, Rheims S, Trébuchon A, Wang H, Liu S, Blauwblomme T, Garcés M, De Palma

L, Valentin A, Metsähonkala EL, Petrescu AM, Landré E, Szurhaj W, Hirsch E,

Valton L, Rocamora R, Schulze-Bonhage A, Mindruta I, Francione S, Maillard L,

Taussig D, Kahane P, David O. (2018) Probabilistic functional tractography of the human

cortex revisited. Neuroimage. 2018 Nov 1;181:414-429. doi:

10.1016/j.neuroimage.2018.07.039. Epub 2018 Jul 17. PubMed PMID: 30025851; PubMed

Central PMCID: PMC6150949.


Derome M, Fonseca-Pedrero E, Badoud D, Morosan L, Van De Ville D, Lazeyras F,

Eliez S, Chan R, Rudrauf D, Schwartz S, Debbane M. (2018) Resting-State Networks of

Adolescents Experiencing Depersonalization-Like Illusions: Cross-sectional and

Longitudinal Findings. Schizophr Bull. 2018 Oct 15;44(suppl_2):S501-S511. doi:

10.1093/schbul/sby031. PubMed PMID: 29566227; PubMed Central PMCID: PMC6188529.


Rudrauf D, Bennequin D, Granic I, Landini G, Friston K, Williford K. (2017) A

mathematical model of embodied consciousness. J Theor Biol. 2017 Sep

7;428:106-131. doi: 10.1016/j.jtbi.2017.05.032. Epub 2017 May 26. PubMed PMID:



Kibleur A, Polosan M, Favre P, Rudrauf D, Bougerol T, Chabardès S, David O. (2017)

Stimulation of subgenual cingulate area decreases limbic top-down effect on

ventral visual stream: A DBS-EEG pilot study. Neuroimage. 2017 Feb 1;146:544-553.

doi: 10.1016/j.neuroimage.2016.10.018. Epub 2016 Oct 13. PubMed PMID: 27743900.


Marrelec G, Messé A, Giron A, Rudrauf D. (2016) Functional Connectivity's Degenerate

View of Brain Computation. PLoS Comput Biol. 2016 Oct 13;12(10):e1005031. doi:

10.1371/journal.pcbi.1005031. eCollection 2016 Oct. PubMed PMID: 27736900; PubMed

Central PMCID: PMC5063374.


Trebaul L, Rudrauf D, Job AS, Mălîia MD, Popa I, Barborica A, Minotti L,

Mîndruţă I, Kahane P, David O. (2016) Stimulation artifact correction method for

estimation of early cortico-cortical evoked potentials. J Neurosci Methods. 2016

May 1;264:94-102. doi: 10.1016/j.jneumeth.2016.03.002. Epub 2016 Mar 4. PubMed

PMID: 26952846; PubMed Central PMCID: PMC4840016.


Mehta S, Inoue K, Rudrauf D, Damasio H, Tranel D, Grabowski T. (2016) Segregation of

anterior temporal regions critical for retrieving names of unique and non-unique

entities reflects underlying long-range connectivity. Cortex. 2016 Feb;75:1-19.

doi: 10.1016/j.cortex.2015.10.020. Epub 2015 Nov 6. PubMed PMID: 26707082; PubMed

Central PMCID: PMC4754140.


Khalsa SS, Rudrauf D, Davidson RJ, Tranel D. (2015) The effect of meditation on

regulation of internal body states. Front Psychol. 2015 Jul 7;6:924. doi:

10.3389/fpsyg.2015.00924. eCollection 2015. PubMed PMID: 26217263; PubMed Central

PMCID: PMC4493770.


Messé A, Rudrauf D, Giron A, Marrelec G. (2015) Predicting functional connectivity

from structural connectivity via computational models using MRI: an extensive

comparison study. Neuroimage. 2015 May 1;111:65-75. doi:

10.1016/j.neuroimage.2015.02.001. Epub 2015 Feb 12. PubMed PMID: 25682944.


Feinstein JS, Khalsa SS, Salomons TV, Prkachin KM, Frey-Law LA, Lee JE,

Tranel D, Rudrauf D. (2016) Preserved emotional awareness of pain in a patient with

extensive bilateral damage to the insula, anterior cingulate, and amygdala. Brain

Struct Funct. 2016 Apr;221(3):1499-511. doi: 10.1007/s00429-014-0986-3. Epub 2015

Jan 11. PubMed PMID: 25577137; PubMed Central PMCID: PMC4734900.


Inoue K, Madhyastha T, Rudrauf D, Mehta S, Grabowski T. (2014) What affects

detectability of lesion-deficit relationships in lesion studies? Neuroimage Clin.

2014 Oct 16;6:388-97. doi: 10.1016/j.nicl.2014.10.002. eCollection 2014. PubMed

PMID: 25379452; PubMed Central PMCID: PMC4218935.


Philippi CL, Tranel D, Duff M, Rudrauf D. (2015) Damage to the default mode network

disrupts autobiographical memory retrieval. Soc Cogn Affect Neurosci. 2015

Mar;10(3):318-26. doi: 10.1093/scan/nsu070. Epub 2014 May 2. PubMed PMID:

24795444; PubMed Central PMCID: PMC4350487.


Messé A, Rudrauf D, Benali H, Marrelec G. (2014) Relating structure and function in

the human brain: relative contributions of anatomy, stationary dynamics, and

non-stationarities. PLoS Comput Biol. 2014 Mar 20;10(3):e1003530. doi:

10.1371/journal.pcbi.1003530. eCollection 2014 Mar. PubMed PMID: 24651524; PubMed

Central PMCID: PMC3961181.


Rudrauf D. (2014) Structure-Function Relationships behind the Phenomenon of Cognitive Resilience in Neurology: Insights for Neuroscience and Medicine, Advances in Neuroscience, vol. 2014, Article ID 462765, 28 pages, doi:10.1155/2014/462765


Mesmoudi S, Perlbarg V, Rudrauf D, Messe A, Pinsard B, Hasboun D, Cioli C,

Marrelec G, Toro R, Benali H, Burnod Y. (2013) Resting state networks' corticotopy: the

dual intertwined rings architecture. PLoS One. 2013 Jul 24;8(7):e67444. doi:

10.1371/journal.pone.0067444. Print 2013. PubMed PMID: 23894288; PubMed Central

PMCID: PMC3722222.


Philippi CL, Feinstein JS, Khalsa SS, Damasio A, Tranel D, Landini G,

Williford K, Rudrauf D. (2012) Preserved self-awareness following extensive bilateral

brain damage to the insula, anterior cingulate, and medial prefrontal cortices.

PLoS One. 2012;7(8):e38413. doi: 10.1371/journal.pone.0038413. Epub 2012 Aug 22.

PubMed PMID: 22927899; PubMed Central PMCID: PMC3425501.


Gläscher J, Adolphs R, Damasio H, Bechara A, Rudrauf D, Calamia M, Paul LK,

Tranel D. (2012) Lesion mapping of cognitive control and value-based decision making in

the prefrontal cortex. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14681-6. doi:

10.1073/pnas.1206608109. Epub 2012 Aug 20. PubMed PMID: 22908286; PubMed Central

PMCID: PMC3437894.


Kovach CK, Daw ND, Rudrauf D, Tranel D, O'Doherty JP, Adolphs R. (2012) Anterior

prefrontal cortex contributes to action selection through tracking of recent

reward trends. J Neurosci. 2012 Jun 20;32(25):8434-42. doi:

10.1523/JNEUROSCI.5468-11.2012. PubMed PMID: 22723683; PubMed Central PMCID:



Paradiso S, Rudrauf D. (2012) Struggle for life, struggle for love and recognition:

the neglected self in social cognitive neuroscience. Dialogues Clin Neurosci.

2012 Mar;14(1):65-75. PubMed PMID: 22577306; PubMed Central PMCID: PMC3341651.


Philippi CL, Duff MC, Denburg NL, Tranel D, Rudrauf D. (2012) Medial PFC damage

abolishes the self-reference effect. J Cogn Neurosci. 2012 Feb;24(2):475-81. doi:

10.1162/jocn_a_00138. Epub 2011 Sep 26. PubMed PMID: 21942762; PubMed Central

PMCID: PMC3297026.


Boes AD, Mehta S, Rudrauf D, Van Der Plas E, Grabowski T, Adolphs R, Nopoulos

P. (2012) Changes in cortical morphology resulting from long-term amygdala damage. Soc

Cogn Affect Neurosci. 2012 Jun;7(5):588-95. doi: 10.1093/scan/nsr047. Epub 2011

Sep 6. PubMed PMID: 21896493; PubMed Central PMCID: PMC3375891.


Kemmerer D, Rudrauf D, Manzel K, Tranel D. (2012) Behavioral patterns and lesion

sites associated with impaired processing of lexical and conceptual knowledge of

actions. Cortex. 2012 Jul;48(7):826-48. doi: 10.1016/j.cortex.2010.11.001. Epub

2010 Nov 18. PubMed PMID: 21159333; PubMed Central PMCID: PMC3965329.


Upadhyay J, Maleki N, Potter J, Elman I, Rudrauf D, Knudsen J, Wallin D,

Pendse G, McDonald L, Griffin M, Anderson J, Nutile L, Renshaw P, Weiss R,

Becerra L, Borsook D. (2010) Alterations in brain structure and functional connectivity

in prescription opioid-dependent patients. Brain. 2010 Jul;133(Pt 7):2098-114.

doi: 10.1093/brain/awq138. Epub 2010 Jun 16. PubMed PMID: 20558415; PubMed

Central PMCID: PMC2912691.


Gläscher J, Rudrauf D, Colom R, Paul LK, Tranel D, Damasio H, Adolphs R. (2010)

Distributed neural system for general intelligence revealed by lesion mapping.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4705-9. doi:

10.1073/pnas.0910397107. Epub 2010 Feb 22. PubMed PMID: 20176936; PubMed Central

PMCID: PMC2842050.


Philippi CL, Mehta S, Grabowski T, Adolphs R, Rudrauf D. (2009) Damage to

association fiber tracts impairs recognition of the facial expression of emotion.

J Neurosci. 2009 Dec 2;29(48):15089-99. doi: 10.1523/JNEUROSCI.0796-09.2009.

PubMed PMID: 19955360; PubMed Central PMCID: PMC2819193.


Khalsa SS, Rudrauf D, Feinstein JS, Tranel D. (2009) The pathways of interoceptive

awareness. Nat Neurosci. 2009 Dec;12(12):1494-6. doi: 10.1038/nn.2411. Epub 2009

Nov 1. PubMed PMID: 19881506; PubMed Central PMCID: PMC2787640.


Feinstein JS, Rudrauf D, Khalsa SS, Cassell MD, Bruss J, Grabowski TJ, Tranel

D. (2010) Bilateral limbic system destruction in man. J Clin Exp Neuropsychol. 2010

Jan;32(1):88-106. doi: 10.1080/13803390903066873. PubMed PMID: 19763994; PubMed

Central PMCID: PMC2888849.


Khalsa SS, Rudrauf D, Tranel D. (2009) Interoceptive awareness declines with age.

Psychophysiology. 2009 Nov;46(6):1130-6. doi: 10.1111/j.1469-8986.2009.00859.x.

Epub 2009 Jul 6. PubMed PMID: 19602175; PubMed Central PMCID: PMC2865139.


Gläscher J, Tranel D, Paul LK, Rudrauf D, Rorden C, Hornaday A, Grabowski T,

Damasio H, Adolphs R. (2009) Lesion mapping of cognitive abilities linked to

intelligence. Neuron. 2009 Mar 12;61(5):681-91. doi:

10.1016/j.neuron.2009.01.026. PubMed PMID: 19285465; PubMed Central PMCID:



Rudrauf D, Lachaux JP, Damasio A, Baillet S, Hugueville L, Martinerie J,

Damasio H, Renault B. (2009) Enter feelings: somatosensory responses following early

stages of visual induction of emotion. Int J Psychophysiol. 2009 Apr;72(1):13-23.

doi: 10.1016/j.ijpsycho.2008.03.015. Epub 2008 Oct 5. PubMed PMID: 18938199.


Khalsa SS, Rudrauf D, Sandesara C, Olshansky B, Tranel D. (2008) Bolus isoproterenol

infusions provide a reliable method for assessing interoceptive awareness. Int J

Psychophysiol. 2009 Apr;72(1):34-45. doi: 10.1016/j.ijpsycho.2008.08.010. Epub

2008 Sep 27. PubMed PMID: 18854201; PubMed Central PMCID: PMC3085829.


Tranel D, Rudrauf D, Vianna EP, Damasio H. (2008) Does the Clock Drawing Test have

focal neuroanatomical correlates? Neuropsychology. 2008 Sep;22(5):553-62. doi:

10.1037/0894-4105.22.5.553. PubMed PMID: 18763875; PubMed Central PMCID:



Rudrauf D, Mehta S, Grabowski TJ. (2008) Disconnection's renaissance takes shape:

Formal incorporation in group-level lesion studies. Cortex. 2008

Sep;44(8):1084-96. doi: 10.1016/j.cortex.2008.05.005. Epub 2008 May 28. PubMed

PMID: 18625495.


Khalsa SS, Rudrauf D, Damasio AR, Davidson RJ, Lutz A, Tranel D. (2008)

Interoceptive awareness in experienced meditators. Psychophysiology. 2008

Jul;45(4):671-7. doi: 10.1111/j.1469-8986.2008.00666.x. Epub 2008 May 20. PubMed

PMID: 18503485; PubMed Central PMCID: PMC2637372.


Rudrauf D, Mehta S, Bruss J, Tranel D, Damasio H, Grabowski TJ. (2008) Thresholding

lesion overlap difference maps: application to category-related naming and

recognition deficits. Neuroimage. 2008 Jul 1;41(3):970-84. doi:

10.1016/j.neuroimage.2007.12.033. Epub 2007 Dec 27. PubMed PMID: 18442925; PubMed

Central PMCID: PMC2582202.


Rudrauf D, David O, Lachaux JP, Kovach CK, Martinerie J, Renault B, Damasio

A. (2008) Rapid interactions between the ventral visual stream and emotion-related

structures rely on a two-pathway architecture. J Neurosci. 2008 Mar

12;28(11):2793-803. doi: 10.1523/JNEUROSCI.3476-07.2008. PubMed PMID: 18337409.


Navarro V, Le Van Quyen M, Martinerie J, Rudrauf D, Baulac M, Menini C. (2007) Loss

of phase synchrony in an animal model of partial status epilepticus.

Neuroscience. 2007 Aug 10;148(1):304-13. Epub 2007 Jul 12. PubMed PMID: 17629413.


Le Van Quyen M, Amor F, Rudrauf D. (2007) Exploring the dynamics of collective

synchronizations in large ensembles of brain signals. J Physiol Paris. 2006

Oct;100(4):194-200. Epub 2007 Jan 17. Review. PubMed PMID: 17317119.


Naqvi NH, Rudrauf D, Damasio H, Bechara A. (2007) Damage to the insula disrupts

addiction to cigarette smoking. Science. 2007 Jan 26;315(5811):531-4. PubMed

PMID: 17255515; PubMed Central PMCID: PMC3698854.


Rudrauf D, Douiri A, Kovach C, Lachaux JP, Cosmelli D, Chavez M, Adam C,

Renault B, Martinerie J, Le Van Quyen M. (2006) Frequency flows and the time-frequency

dynamics of multivariate phase synchronization in brain signals. Neuroimage. 2006

May 15;31(1):209-27. Epub 2006 Jan 18. PubMed PMID: 16413209.


Rudrauf D, Venault P, Cohen-Salmon C, Berthoz A, Jouvent R, Chapouthier G. (2004) A

new method for the assessment of spatial orientation and spatial anxiety in mice.

Brain Res Brain Res Protoc. 2004 Aug;13(3):159-65. PubMed PMID: 15296853.


Le Van Quyen M, Chavez M, Rudrauf D, Martinerie J. (2003) Exploring the nonlinear

dynamics of the brain. J Physiol Paris. 2003 Jul-Nov;97(4-6):629-39. Review.

PubMed PMID: 15242671.


Lachaux JP, Rudrauf D, Kahane P. (2003) Intracranial EEG and human brain mapping. J

Physiol Paris. 2003 Jul-Nov;97(4-6):613-28. Review. PubMed PMID: 15242670.


Rudrauf D, Lutz A, Cosmelli D, Lachaux JP, Le Van Quyen M. (2003) From autopoiesis

to neurophenomenology: Francisco Varela's exploration of the biophysics of being.

Biol Res. 2003;36(1):27-65. Review. PubMed PMID: 12795206.


Lachaux JP, Lutz A, Rudrauf D, Cosmelli D, Le Van Quyen M, Martinerie J,

Varela F. (2002) Estimating the time-course of coherence between single-trial brain

signals: an introduction to wavelet coherence. Neurophysiol Clin. 2002

Jun;32(3):157-74. Review. PubMed PMID: 12162182.


Venault P, Rudrauf D, Lepicard EM, Berthoz A, Jouvent R, Chapouthier G. (2001)

Balance control and posture in anxious mice improved by SSRI treatment.

Neuroreport. 2001 Oct 8;12(14):3091-4. PubMed PMID: 11568643.