SPECIAL ISSUES

ITC2 2013

Clin Pharmacol Ther. 2013;94:3-9. Transporters in drug development and clinical pharmacology. Giacomini KM, Huang SM. PubMed

Clin Pharmacol Ther. 2013;94:23-6. International Transporter Consortium commentary on clinically important transporter polymorphisms. Giacomini KM, Balimane PV, Cho SK, Eadon M, Edeki T, Hillgren KM, Huang SM, Sugiyama Y, Weitz D, Wen Y, Xia CQ, Yee SW, Zimdahl H, Niemi M; International Transporter Consortium. PubMed

Clin Pharmacol Ther. 2013;94:52-63. Emerging transporters of clinical importance: an update from the International Transporter Consortium. Hillgren KM, Keppler D, Zur AA, Giacomini KM, Stieger B, Cass CE, Zhang L; International Transporter Consortium. PubMed

Clin Pharmacol Ther. 2013;94:95-112. In vitro methods to support transporter evaluation in drug discovery and development. Brouwer KL, Keppler D, Hoffmaster KA, Bow DA, Cheng Y, Lai Y, Palm JE, Stieger B, Evers R; International Transporter Consortium. PubMed

Clin Pharmacol Ther. 2013;94:113-25.Transporter studies in drug development: experience to date and follow-up on decision trees from the International Transporter Consortium. Tweedie D, Polli JW, Berglund EG, Huang SM, Zhang L, Poirier A, Chu X, Feng B; International Transporter Consortium. PubMed

Clin Pharmacol Ther. 2013;94:126-41. Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver. Chu X, Korzekwa K, Elsby R, Fenner K, Galetin A, Lai Y, Matsson P, Moss A, Nagar S, Rosania GR, Bai JP, Polli JW, Sugiyama Y, Brouwer KL; International Transporter Consortium. PubMed