IMAGING

Sara EYAL

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Mol Pharm. 2021;18:2263-2273. Abundance of P-glycoprotein and Breast Cancer Resistance Protein measured by targeted proteomics in human epileptogenic brain tissue. Brukner AM, Billington S, Benifla M, Nguyen TB, Han H, Bennett O, Gilboa T, Blatch D, Fellig Y, Volkov O, Unadkat JD, Ekstein D, Eyal S. PubMed

Front Pharmacol. 2018;9:1054.  Effects of Valproic Acid on cerebral nutrient carriers' expression in the rat. Mann Brukner A, Ben-Hur T, Honig A, Ekstein D, Eyal S. PubMed

Epilepsia. 2018;59:993-1003. Adverse placental effects of valproic acid: Studies in perfused human placentas. Rubinchik-Stern M, Shmuel M, Bar J, Kovo M, Eyal S. PubMed

Pharm Res. 2018;35:71. The placental barrier: the gate and the fate in drug distribution. Tetro N, Moushaev S, Rubinchik-Stern M, Eyal S. PubMed

J Control Release. 2017;257:2-9. Therapeutic efficacy of combined PEGylated liposomal doxorubicin and radiofrequency ablation: Comparing single and combined therapy in young and old mice. Andriyanov AV, Portnoy E, Koren E, Inesa S, Eyal S, Goldberg SN, Barenholz Y. PubMed

Surg Innov. 2017;24:139-144. Intraoperative localization of rectal tumors using liposomal Indocyanine Green. Magdassi S, Bar-David S, Friedman-Levi Y, Zigmond E, Varol C, Lahat G, Klausner J, Eyal S, Nizri E. PubMed

Front Pharmacol. 2016;7:426. Evaluation of Near Infrared dyes as markers of P-Glycoprotein activity in tumors. Semenenko I, Portnoy E, Aboukaoud M, Guzy S, Shmuel M, Itzhak G, Eyal S. PubMed

Clin Pharmacol Ther. 2016;100:479-488. Imaging transporters: Transforming diagnostic and therapeutic development. Mann A, Han H, Eyal S. PubMed

Mol Pharm. 2015;12:3351-7. Near infrared imaging of Indocyanine Green distribution in pregnant mice and effects of concomitant dedications. Bishara A, Meir M, Portnoy E, Shmuel M, Eyal S. PubMed

Epilepsia. 2015;56:1023-32. Antiepileptic drugs alter the expression of placental carriers: An in vitro study in a human placental cell line. Rubinchik-Stern M, Shmuel M, Eyal S. PubMed

AAPS J. 2015;17:788-801. Molecular imaging of membrane transporters' activity in cancer: a picture is worth a thousand tubes.Mann A, Semenenko I, Meir M, Eyal S. PubMed

J Nucl Med. 2014;55:1106-11. Activity of P-Glycoprotein, a β-Amyloid transporter at the Blood-Brain Barrier, is compromised in patients with mild Alzheimer disease. Deo AK, Borson S, Link JM, Domino K, Eary JF, Ke B, Richards TL, Mankoff DA, Minoshima S, O'Sullivan F, Eyal S, Hsiao P, Maravilla K, Unadkat JD. PubMed

Med Hypotheses. 2013;81:1059-62. The role of aquaporin-1 in idiopathic and drug-induced intracranial hypertension. Stiebel-Kalish H, Eyal S, Steiner I. PubMed

J Nucl Med. 2013;54:437-46. Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition. Ke AB, Eyal S, Chung FS, Link JM, Mankoff DA, Muzi M, Unadkat JD. PubMed

Mol Pharm. 2012;9:3595-601. Evaluation of the near infrared compound indocyanine green as a probe substrate of p-glycoprotein. Portnoy E, Gurina M, Magdassi S, Eyal S. PubMed

Front Pharmacol. 2012;3:126. Drug interactions at the human placenta: What is the evidence? Rubinchik-Stern M, Eyal S. PubMed

Clin Pharmacol Ther. 2010;87:579-85. Regional P-glycoprotein activity and inhibition at the human blood-brain barrier as imaged by positron emission tomography. Eyal S, Ke B, Muzi M, Link JM, Mankoff DA, Collier AC, Unadkat JD. PubMed

Drug Metab Dispos. 2010;38:833-40. Pharmacokinetics of metformin during pregnancy. Eyal S, Easterling TR, Carr D, Umans JG, Miodovnik M, Hankins GD, Clark SM, Risler L, Wang J, Kelly EJ, Shen DD, Hebert MF. PubMed

Br J Pharmacol. 2010;159:394-404. Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primate. Chung FS, Eyal S, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hsiao P, Unadkat JD. PubMed

Mol Pharm. 2009;6:1883-90. The role of P-glycoprotein in intestinal transport versus the BBB transport of tetraphenylphosphonium. Swed A, Eyal S, Madar I, Zohar-Kontante H, Weiss L, Hoffman A. PubMed

J Nucl Med. 2009;50:798-806. Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant nonhuman primate. Eyal S, Chung FS, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hebert MF, Unadkat JD. PubMed

Pharmacol Ther. 2009;123:80-104. Drug interactions at the blood-brain barrier: fact or fantasy? Eyal S, Hsiao P, Unadkat JD. PubMed

Br J Pharmacol. 2006;149:250-60. The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver. Eyal S, Lamb JG, Smith-Yockman M, Yagen B, Fibach E, Altschuler Y, White HS, Bialer M. PubMed