Mary VORE GROUP SITE

  • J Pharmacol Exp Ther. 2019;371:713-717. Hepatic bile formation: Canalicular osmolarity and paracellular and transcellular water flow. Marinelli RA, Vore M, Javitt NB. PubMed
  • Curr Med Chem. 2019;26:1155-1184. ABC transporters in extrahepatic tissues: Pharmacological regulation in heart and intestine. Villanueva S, Zhang W, Zecchinati F, Mottino A, Vore M. PubMed
  • J Pharmacol Exp Ther. 2015;355:272-9. Elevated glutathione is not sufficient to protect against doxorubicin-induced nuclear damage in heart in multidrug resistance-associated protein 1 (Mrp1/Abcc1) null mice. Deng J, Coy D, Zhang W, Sunkara M, Morris AJ, Wang C, Chaiswing L, St Clair D1, Vore M, Jungsuwadee P. PubMed
  • Toxicology. 2014;320:46-55. Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity. Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, Vore M, Catania VA, Mottino AD. PubMed
  • Compr Physiol. 2013;3:1721-40. Hormonal regulation of hepatic drug biotransformation and transport systems. Ruiz ML, Mottino AD, Catania VA, Vore M. PubMed
  • Biochem Pharmacol. 2013;86:401-9. Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17α-ethynylestradiol. Role of activator protein-1. Ruiz ML, Rigalli JP, Arias A, Villanueva SS, Banchio C, Vore M, Mottino AD, Catania VA. PubMed
  • Drug Metab Dispos. 2013;41:275-80. Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor. Ruiz ML, Rigalli JP, Arias A, Villanueva S, Banchio C, Vore M, Mottino AD, Catania VA. PubMed
  • J Biol Chem. 2012;287:24784-94. Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice. Zhang Y, Li F, Patterson AD, Wang Y, Krausz KW, Neale G, Thomas S, Nachagari D, Vogel P, Vore M, Gonzalez FJ, Schuetz JD. PubMed
  • Drug Metab Dispos. 2012;40:1252-8. Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene. Villanueva SS, Perdomo VG, Ruiz ML, Rigalli JP, Arias A, Luquita MG, Vore M, Catania VA, Mottino AD. PubMed
  • Pharmacogenet Genomics. 2012;22:273-84. The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. Jungsuwadee P, Zhao T, Stolarczyk EI, Paumi CM, Butterfield DA, St Clair DK, Vore M. PubMed
  • Pharmacogenet Genomics. 2011;21:506-15. Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2). Megaraj V, Zhao T, Paumi CM, Gerk PM, Kim RB, Vore M. PubMed
  • BMC Genomics. 2011;12:95. Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes. Athippozhy A, Huang L, Wooton-Kee CR, Zhao T, Jungsuwadee P, Stromberg AJ, Vore M. PubMed
  • Hepatology. 2010;52:1465-76. Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17β-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C. Boaglio AC, Zucchetti AE, Sánchez Pozzi EJ, Pellegrino JM, Ochoa JE, Mottino AD, Vore M, Crocenzi FA, Roma MG. PubMed
  • J Pharmacol Exp Ther. 2010;335:332-41. Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat. Villanueva SS, Arias A, Ruiz ML, Rigalli JP, Pellegrino JM, Vore M, Catania VA, Mottino AD. PubMed
  • Drug Metab Dispos. 2010;38:1723-30. Hepatobiliary disposition of 3alpha,6alpha,7alpha,12alpha-tetrahydroxy-cholanoyl taurine: a substrate for multiple canalicular transporters. Megaraj V, Iida T, Jungsuwadee P, Hofmann AF, Vore M. PubMed
  • Am J Physiol Gastrointest Liver Physiol. 2010;299:G228-35. ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats. Coy DJ, Wooton-Kee CR, Yan B, Sabeva N, Su K, Graf G, Vore M. PubMed
  • Mol Pharmacol. 2010;77:237-46. The 5'-untranslated region of multidrug resistance associated protein 2 (MRP2; ABCC2) regulates downstream open reading frame expression through translational regulation. Zhang Y, Zhao T, Li W, Vore M. PubMed
  • Drug Metab Dispos. 2009;37:1277-85. Regulation of expression and activity of rat intestinal multidrug resistance-associated protein 2 by cholestatic estrogens. Arias A, Villanueva SS, Ruiz ML, Luquita MG, Veggi LM, Pellegrino JM, Vore M, Catania VA, Mottino AD. PubMed
  • Mol Pharmacol. 2009;75:1117-26. Mrp1 localization and function in cardiac mitochondria after doxorubicin. Jungsuwadee P, Nithipongvanitch R, Chen Y, Oberley TD, Butterfield DA, St Clair DK, Vore M. PubMed
  • Hepatology. 2008;48:1885-95. Ca(2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat. Crocenzi FA, Sánchez Pozzi EJ, Ruiz ML, Zucchetti AE, Roma MG, Mottino AD, Vore M. PubMed
  • Mol Pharmacol. 2008;73:613-5. Progesterone acts via progesterone receptors A and B to regulate breast cancer resistance protein expression. Vore M, Leggas M. PubMed
  • Am J Physiol Gastrointest Liver Physiol. 2007;293:G391-402. Disruption of function and localization of tight junctional structures and Mrp2 in sustained estradiol-17beta-D-glucuronide-induced cholestasis. Mottino AD, Hoffman T, Crocenzi FA, Sánchez Pozzi EJ, Roma MG, Vore M. PubMed
  • Mol Cancer Ther. 2006;5:2851-60. Increase in Mrp1 expression and 4-hydroxy-2-nonenal adduction in heart tissue of Adriamycin-treated C57BL/6 mice. Jungsuwadee P, Cole MP, Sultana R, Joshi G, Tangpong J, Butterfield DA, St Clair DK, Vore M. PubMed
  • J Pharmacol Exp Ther. 2007;320:893-9. Human multidrug resistance protein 2 transports the therapeutic bile salt tauroursodeoxycholate. Gerk PM, Li W, Megaraj V, Vore M. PubMed
  • Mol Pharmacol. 2007;71:377-83. Translational regulation of rat multidrug resistance-associated protein 2 expression is mediated by upstream open reading frames in the 5' untranslated region. Zhang Y, Li W, Vore M. PubMed
  • Drug Metab Dispos. 2006;34:1030-4. Ethynylestradiol increases expression and activity of rat liver MRP3. Ruiz ML, Villanueva SS, Luquita MG, Vore M, Mottino AD, Catania VA. PubMed
  • J Hepatol. 2006;44:232-3. Canalicular membrane localization of hepatocyte aquaporin-8 is preserved in estradiol-17beta-D-glucuronide-induced cholestasis. Mottino AD, Carreras FI, Gradilone SA, Marinelli RA, Vore M. PubMed
  • Mol Pharmacol. 2005;68:701-10. The role of protein synthesis and degradation in the post-transcriptional regulation of rat multidrug resistance-associated protein 2 (Mrp2, Abcc2). Jones BR, Li W, Cao J, Hoffman TA, Gerk PM, Vore M. PubMed
  • Mol Pharmacol. 2005;68:218-25. Hormonal regulation of hepatic organic anion transporting polypeptides. Wood M, Ananthanarayanan M, Jones B, Wooton-Kee R, Hoffman T, Suchy FJ, Vore M. PubMed
  • Biochem Pharmacol. 2005;69:531-9. Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2. Ruiz ML, Villanueva SS, Luquita MG, Sánchez-Pozzi EJ, Crocenzi FA, Pellegrino JM, Ochoa JE, Vore M, Mottino AD, Catania VA. PubMed
  • Am J Physiol Gastrointest Liver Physiol. 2005;288:G327-36. Role of microtubules in estradiol-17beta-D-glucuronide-induced alteration of canalicular Mrp2 localization and activity. Mottino AD, Crocenzi FA, Pozzi EJ, Veggi LM, Roma MG, Vore M. PubMed
  • Drug Metab Dispos. 2004;32:1139-45. Estradiol 3-glucuronide is transported by the multidrug resistance-associated protein 2 but does not activate the allosteric site bound by estradiol 17-glucuronide. Gerk PM, Li W, Vore M. PubMed
  • Endocrinology. 2004;145:1739-49. Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in liver cells through estrogen receptor-alpha and signal transducers and activators of transcription 5a. Cao J, Wood M, Liu Y, Hoffman T, Hyde J, Park-Sarge OK, Vore M. PubMed
  • J Pharmacol Exp Ther. 2003;307:306-13. Biliary secretion of glutathione in estradiol 17beta-D-glucuronide-induced cholestasis. Mottino AD, Veggi LM, Wood M, Román JM, Vore M. PubMed

PubMed

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Last update: June 2021