Group Giacobino Ariane (genetics)
-Exploration of the epigenetic modifications subsequent to different types of environmental exposures, such as exposure to toxic compounds (among which endocrine disruptors).
Different period of exposures during pregnancy are the target of our explorations. We focus on methylation changes, as epigenetic modifications.
-Exploration of specific phenotypes, such as male infertility or uro-genital malformations, as possibly subsequent to specific environmental exposures. -Several collaborations on methylation changes suspected to be involved in human diseases.