[880] Developmental neurobiology and cerebral plasticity
Our lab is interested in the understanding of the molecular/genetic programs that control cortical neuronal circuit formation. More specifically, we investigate how distinct subtypes of forebrain neurons are programmed during development to establish their unique connectivity, and how these programs can be manipulated to promote re-wiring and functional recovery in neurodegenerative diseases or after injury.
The approaches we use to address these questions include in vivo genetic gain-and-loss of function approaches, including in utero electroporation; structural and functional analysis of transgenic mice, and electrophysiology.