Pierre Cosson



Lima, W.C., Gasteiger, E., Marcatili, P., Duek, P., Bairoch, A., Cosson, P. 2018. The ABCD database: a repository for chemically defined antibodies. Nucleic Acids Res. in press

Lima, W.C., Gasteiger, E., Marcatili, P., Duek, P., Bairoch, A., Cosson, P. 2019. LrrkA, a kinase with Leucine-Rich Repeats links folate sensing with Kil2 activity and intracellular killing. Cell Microbiol. e13129



Dhakshinamoorthy, R., Bitzhenner, M., Cosson, P., Soldati, T., Leippe, M. 2018. The saposin-like protein AplD displays pore-forming activity and participates in defence against bacterial infection during a multicellular stage of Dictyostelium discoideum. Front. Cell. Infect. Biol.8:73

Perrin, J., Bary, A., Vernay, A., Cosson, P. 2018. Role of the HIV-1 envelope transmembrane domain in intracellular sorting. BMC Cell Biol. 19:3

 Lima, W.C., Pillonel, T., Bertelli, C., Ifrid, E., Greub, G., Cosson, P. 2018. Genome sequencing and functional characterization of the non-pathogenic Klebsiella pneumoniae KpGe bacteria. Microbes and Infection. 20:293-301

 Sattler, N., Bosmani, C., Barisch, C., Ghého, A., Gopaldass, N., Dias, M., Leuba, F., Bruckert, F., Cosson, P., Soldati, T. 2018. Functions of the Dictyostelium LIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence. J. Cell Sci.131:jcs218040

 Vernay,A., Lamrabet, O., Perrin, J., Cosson, P. 2018. TM9SF4 levels determine sorting of transmembrane domains in the early secretory pathway. J. Cell Sci.131:jcs220830

 Hammel, P., Lima, W.C., Hartley, O., Cosson, P. 2018. RB250 and RB251 antibodies recognize the human MitoNEET/CISD1 protein by ELISA. Antibody Rep.1:e1



Leiba, J., Sabra, A., Bodinier, R., Marchetti, A., Lima, W.C., Melotti, A., Perrin, J., Burdet, F., Pagni, M., Soldati, T., Lelong, E., Cosson, P. 2017. Vps13F links bacterial recognition and intracellular killing in Dictyostelium. Cell. Microb.19:e12722

 Vernay, A., Marchetti, A., Sabra, A., Scherer, P., Orci, L., Cosson, P. 2017. MitoNEET-dependent formation of inter-mitochondrial junctions. Proc. Natl. Acad. Sci. USA. 114:8277-82

 Ouertatani-Sakouhi, H., Kicka, S., Gianpaolo, C., Harrison, C., Hilbi, H., Scapozza, L., Soldati, T., Cosson, P. 2017. Inhibitors of Mycobacterium marinum virulence. Plos One12:e0181121



Slepikas, L., Chiriano, G.,  Perozzo, R., Tardy, S., Kranjc-Pietrucci, A., Patthey-Vuadens, O., Ouertatani-Sakouhi, H., Kicka, S., Harrison, C., Scrignari, T., Perron, K., Hilbi, H., Soldati, T., Cosson, P., Tarasevicius, E., Scapozza, L. 2016. In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA. J. Medicinal Chem. 59 :10917-28.

 Sabra, A., Leiba, J., Mas, L., Louwagie, M., Couté, Y., Journet, A., Cosson, P., Aubry, L. 2016. Pycnosomes: condensed endosomal structures secreted by Dictyostelium amoebae. PLOS One11:e0154875.

 Delincé, M.J., Bureau, J.B., Lopez-Jimenez, A.T., Cosson, P., Soldati, T., McKinney, J.D. 2016. A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions. Lab on a Chip16:3276-85.

Dias, M., Brochetta, C., Marchetti, A., Bodinier, R., Brüchert, F., Cosson, P. 2016. Role of SpdA in cell spreading and phagocytosis in Dictyostelium. PLOS One11:e0160376



Saüc, S., Bulla, M., Nunes, P., Orci, L., Marchetti, A., Antigny, F., Bernheim, L., Cosson, P., Frieden, M., Demaurex, N. 2015. STIM1L traps and gates Oria1 channels without remodeling the cortical ER. J. Cell Sci. 128:1568-79.

 Perrin, J., Le Coadic, M., Vernay, A., Dias, M., Gopaldass, N., Ouertatani-Sakouhi, H., Cosson, P. 2015. TM9 proteins control surface targeting of glycine-rich transmembrane domains. J. Cell Sci. 128: 2269-77.



Cosson, P, Lima, WC. 2014. Intracellular killing of bacteria: is Dictyostelium a model macrophage or an alien? Cell. Microbiol. 16:816-23.

Blanc, C., Zufferey, M., Cosson, P. 2014. Use of in vivo biotinylated GST fusion proteins to select recombinant antibodies. ALTEX. 31:37-42.

Lima, W., Balestrino, D., Forestier, C., Cosson, P. 2014. Two distinct sensing pathways allow recognition of Klebsiella pneumoniae by Dictyostelium amoebae. Cell. Microb. 16:311-23. “Selected as Editor’s choice”.

Vinet, A.F., Fiedler, T., Studer, V., Froquet, R., Dardel, A., Cosson, P., Pieters, J. 2014. Initiation of multicellular differentiation in Dictyostelium discoideum regulated by coronin A. Mol. Biol. Cell 25:688-701.

Köhler, T. Ouertatani, H., Cosson, P., van Delden, C. 2014. QsrO a novel regulator of quorum-sensing and virulence in Pseudomonas aeruginosa. PLOS One 9:e87814.

Kicka, S., Trofimov, V., Harrison, C., Ouertatani, H., McKinney, J., Scapozza, L., Hilbi, H., Cosson, P., Soldati, T. 2014. Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii - Mycobacterium marinum host-pathogen system. PLOS One 9:e87834.

Lima, W.C., Vinet, A., Pieters, J., Cosson, P. 2014. Role of PKD2 in rheotaxis in Dictyostelium. PLOS One9:e88682.

Baïlo, N., Cosson, P., Charette, S.J., Paquet, V.E., Doublet, P., Letourneur, F. 2014. Defective lysosome maturation and Legionella pneumophila replication in Dictyostelium ArfGAP ACAP-A mutant cells. J. Cell Sci. 127:4702-13.



 Lima, WC, Cosson, P. 2013. Secretory lysosomes in Dictyostelium: visualization, characterization, and dynamics. Methods Mol. Biol. 983:445-59.

 Cosson, P, Perrin, J, Bonifacino JS. 2013. Anchors aweigh: protein localization and transport mediated by transmembrane domains. Trends in Cell Biol. 23:511-7. “Top 10 Editorial Board Favorites for 2013”.

Dias, M., Blanc, C., Thazar-Poulot, N., Ben Larbi, L., Cosson, P., Letourneur, F. 2013. Dictyostelium ACAP-A is an ArfGAP involved in cytokinesis, cell migration and actin cytoskeleton dynamics. J. Cell Sci. 126;756-66.

Le Coadic, M., Froquet, R., De Lima, W., Dias, M., Marchetti, A., Cosson, P. 2013. Phg1/TM9 proteins control intracellular killing of bacteria by determining cellular levels of the Kil1 sulfotransferase in Dictyostelium. PLOS One, 8:e53259.

Vernay, A., Cosson, P. 2013. Immunofluorescence labeling of cell surface antigens in Dictyostelium. BMC Res. Notes 6:317.

Harrison, C., Kicka, S., Trofimov, V., Berschl, K., Ouertatani-Sakouhi, H., Ackermann, N., Hedberg, C., Cosson, P., Soldati, T., Hilbi, H. 2013. Exploring anti-bacterial compounds against intracellular Legionella. PLOS One. 8:e74813.



Le Coadic, M., Simon, M., Marchetti, A., Ebert, D., Cosson, P. 2012. Daphnia magna, a host to evaluate bacterial virulence. Appl. Environ. Microbiol. 78:593-5.

Froquet, R., le Coadic, M., Perrin, J., Cherix, N., Cornillon, S., Cosson, P. 2012. TM9/Phg1 and SadA proteins control surface expression and stability of SibA adhesion molecules in Dictyostelium. Mol. Biol. Cell 23:679-86.

Lima, W.C., Leuba, F., Soldati, T., Cosson, P. 2012. Mucolipin controls lysosome exocytosis in Dictyostelium. J. Cell Sci. 125:2315-22.

Cosson, P., Marchetti, A., Ravazzola, M., Orci, L. 2012. Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria : an ultrastructural study. PLOS One 7: e46293.



Lima, WC, Lelong, E, Cosson, P. 2011. What can Dictyostelium bring to the study of Pseudomonas infections? Seminars-Cell. Dev. Biol. 22:77-81.

Lelong, E., Marchetti, A., Guého, A., Lima, W.C., Sattler, N., Molmeret, M., Hagedorn, M., Soldati, T., Cosson, P. 2011. Role of magnesium and a phagosomal P-type ATPase in intracellular bacterial killing. Cell. Microb. 13:246-58.

Lelong, E., Marchetti, A., Simon, M., Burns, J.L., van Delden, C., Köhler, T., Cosson, P. 2011. Evolution of Pseudomonas aeruginosa virulence in infected patients revealed in a Dictyostelium discoideum host model. Clin. Microb. Infect. 17:1415-20.



Smith, E.W., Lima, W.C., Charette, S.J., Cosson, P. 2010. Effect of starvation on the endocytic pathway of Dictyostelium cells. Euk. Cell. 9:387-92.

Lavieu, G., Orci, L.,Shi, L., Geiling, M., Ravazzola, M., Wieland, F., Cosson, P., Rothman, J.E. 2010. Induction of cortical endoplasmic reticulum by dimerization of a coatomer-binding peptide anchored to endoplasmic reticulum membranes. Proc. Natl. Acad. Sci. USA. 107:6876-81 

Mercanti, V., Cosson, P. 2010. Resistance of Dictyostelium discoideum membranes to saponin permeabilization. BMC Res. Notes 3:120.

Mercanti, V., Marchetti, A., Lelong, E., Perez, F., Orci, L., Cosson, P. 2010. Transmembrane domains control exclusion of membrane proteins from clathrin-coated pits. J. Cell Sci. 123:3329-35.