Dr Devashish Dwivedi
Devashish is Junior Lecturer (Maître Assistant) in Meraldi Lab at the University of Geneva. He is a cell-biologist interested in understanding how the centrosome duplication is synchronised with the cell cycle.
He did his PhD at the Indian Institute of Science Education and Research, Mohali, India. During his PhD studies, Devashish worked on the role of Hook2, a cytoplasmic dynein activating adaptor in regulating mitosis and cytokinesis, where he learned molecular biology, advanced microscopy and biochemical assays. In 2019, Devashish joined the Meraldi lab as a postdoctoral fellow. Devashish focuses on the molecular mechanisms governing the progression of the cell and centrosome cycle.
He is inspiring to begin his scientific career studying how different events during the centriole duplication cycle are synchronised with the cell cycle as both processes share multiple regulatory proteins. Since both the systems are dysregulated in tumours and cancers, his work also carries implications for public health.
In addition to scientific experiments, Devashish likes watching movies, travelling, hiking, and photography when not in the lab.
Le Roux-Bourdieu M.§, Dwivedi D.§, Harry D. and Meraldi P. (2022) “PLK1 controls centriole distal appendage formation and centrobin removal via independent pathways.” Journal of Cell Science, 135(8), DOI: 10.1242/jcs.259120. (§ equal contribution).
Dwivedi D.*,Kumari A., Rathi S., Mylavarapu S.V.S. and Sharma M.* (2019) “The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis.” The Journal of Cell Biology, 218(3) 871. (*Corresponding author). This research article was featured on the cover of Journal of Cell Biology; March-2019 issue.
Sharma M., and Dwivedi D.(2019) “A CRACker of an adaptor connects dynein-mediated transport to calcium signalling.” The Journal of Cell Biology, 218(5) 1429.
Dwivedi D.§, Chawla P.§, and Sharma M., (2019) “Incorporating motility in motor: Role of Hook protein family in regulating dynein motility.” Biochemistry, 58(8): 1026. (§ equal contribution).
Marwaha R., Dwivedi D. and Sharma M., (2019) “Emerging roles of Arf-like GTP-binding proteins: from membrane trafficking to cytoskeleton dynamics and beyond.” Proceedings of Indian National Science Academy, DOI: 10.16943/ptinsa/2019/49574.
Dwivedi, D.* and Sharma, M.* (2018). “Multiple roles, multiple adaptors: Dynein during cell cycle.” Book Chapter published in Biochemical and Biophysical Roles of Cell Surface Molecules, Springer Advances in Experimental Medicine and Biology, published by Springer, Singapore. 1112: 13. (*Corresponding author)
Khatter D., Raina V. B., Dwivedi D., Sindhwani A., Bahl S. and Sharma M., (2015) "The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes." Journal of Cell Science 128(9): 1746.