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Despite its obvious function in nutrient digestion and absorption, little is known about the role of gut in the regulation of our energy balance. In recent years, gut microbiota has emerged as an important factor that determines efficiency of energy uptake and influences susceptibility of an individual to obesity. I am interested in the interactions between microbiota and gut function. The project will explore the potential of the gut as a novel target for treatment of obesity, the molecular mechanisms involved in shaping of gut and interactions with other key metabolic organs.