Success stories

New coordination project with UNIGE lead

UNIGE coordinates 6 H2020 projects. VANGUARD is the only one in the section Health.

European framework programme H2020, Societal Challenges (3rd pillar) « Health, Demographic Change and Wellbeing »

VANGUARD – Bioartificial Pancreas to Cure Type 1 Diabetes (Project ID : 874 700)

Duration : 5 years
Budget : € 6 844 625
Start date : 01.01.2020

Kick-off meeting et press release : see Commission website and consortium website

Consortium : 6 research institutions, 2 SMEs and 1 NGO

University of Geneva (Switzerland) (Coordonator : E. Berishvili)

Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (Italy)
Lyon Claude Bernard University (France)
IRCCS Ospedale San Raffaele (Italy)
Ludwig-Maximilians-Universität München (Germany)
Erasmus University Medical Center Rotterdam (The Netherlands)
2 SMEs : Kugelmeiers AG and accelopment AG
1 NGO : European Society for Organ Transplantation

Project aim and scope : (extract of

Type 1 diabetes is managed by insulin therapy in a vast majority of patients because of the limited accessibility of beta cell replacement therapies (pancreas or islet of Langerhans transplantation). There is an urgent need for the development of a beta cell replacement therapy that will be available to larger numbers of type 1 diabetic patients.

The VANGUARD project aims to deliver an Advanced Therapeutic Medicinal Product (ATMP) of high translational potential, with properties of increased functionality and implantability and protection from immune destruction.

The ATMP delivered upon completion of the project will provide a model for rapid development of a bioartificial pancreas, utilizing “infinite” sources of insulin-producing cells (stem cell-derived, xenogeneic), and available to all type 1 diabetic patients before they develop the devastating chronic complications of the disease.

Funder website :
Project website



Published on the 2nd of March 2020 / hg