Aurélien Roux Lab
Many biological systems are made of viscoelastic surfaces. For example, the lipid bilayer that delimitates cells from their environment is a 2D fluid interface/barrier that can be deformed easily and is resistant to stretch.
The plasma membrane is being constantly remodelled through processes such as endocytosis in membrane traffic. Another example, but at a different scale, is the epithelium, a cell monolayer that separates organs from the external environment. These epithelia grow and fold during development to form organs, being viscoelastic surfaces. We are interested in understanding how the unique physical properties of lipid membrane and epithelia respectively contribute to membrane traffic and organogenesis.
To study this, we use in vitro models to measure relevant physical parameters, such as forces, rigidity, tension, and diffusion constants.