Howard Riezman

Publications

2020

2019

  • Haribowo, A. Galih; Hannich, J. Thomas; Michel, Agnès H.; Megyeri, Márton; Schuldiner, Maya; Kornmann, Benoît; Riezman, Howard; Parton, Robert G. (2019) Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae. Mol. Biol. Cell 30 (22) 2814-2826.
  • Chang, Dalu; Lindberg, Eric; Feng, Suihan; Angerani, Simona; Riezman, Howard; Winssinger, Nicolas (2019) Luciferase-Induced Photouncaging: Bioluminolysis. Angew. Chem. Int. Ed. 58 (45) 16033-16037.
  • Jiménez-Rojo, Noemi; Riezman, Howard (2019) On the road to unraveling the molecular functions of ether lipids. FEBS Lett. 593 (17) 2378-2389.
  • Megyeri, Márton; Prasad, Rupali; Volpert, Giora; Sliwa-Gonzalez, Andrzej; Galih, Augustinus; Aguilera-Romero, Auxiliadora; Riezman, Howard; Barral, Yves; Futerman, Anthony H.; Schuldiner, Maya (2019) Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity. J. Cell. Sci. 132 jcs228411.
  • Morstein, Johannes; Hill, Rose Z.; Novak, Alexander J. E.; Feng, Suihan; Norman, Derek D.; Donthamsetti, Prashant C.; Frank, James A.; Harayama, Takeshi; Williams, Benjamin M.; Parrill, Abby L.; Tigyi, Gabor J.; Riezman, Howard; Isacoff, Ehud Y.; Bautista, Diana M.; Trauner, Dirk (2019) Optical control of sphingosine-1-phosphate formation and function. Nat. Chem. Biol. 15 623-631.
  • Loewith, Robbie; Riezman, Howard; Winssinger, Nicolas (2019) Sphingolipids and membrane targets for therapeutics. Curr. Opin. Chem. Biol. 50 19-28.
  • Feng, Suihan; Harayama, Takeshi; Chang, Dalu; Hannich, J. Thomas; Winssinger, Nicolas; Riezman, Howard (2019) Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures. Chem. Sci. 10 (8) 2253-2258.
  • Sundukova, Mayya; Prifti, Efthymia; Bucci, Annalisa; Kirillova, Kseniia; Serrao, Joana; Reymond, Luc; Umebayashi, Miwa; Hovius, Ruud; Riezman, Howard; Johnsson, Kai; Heppenstall, Paul A. (2019) A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons. Angew. Chem. Int. Ed. 58 (8) 2341-2344.

2018

  • He, Cuiwen; Hu, Xuchen; Weston, Thomas A.; Jung, Rachel S.; Sandhu, Jaspreet; Huang, Song; Heizer, Patrick; Kim, Jason; Ellison, Rochelle; Xu, Jiake; Kilburn, Matthew; Bensinger, Steven J.; Riezman, Howard; Tontonoz, Peter; Fong, Loren G.; Jiang, Haibo; Young, Stephen G. (2018) Macrophages release plasma membrane-derived particles rich in accessible cholesterol. Proc. Natl. Acad. Sci. USA 115 (36) E8499-E8508.
  • Melero, Alejandro; Chiaruttini, Nicolas; Karashima, Takefumi; Riezman, Isabelle; Funato, Kouichi; Barlowe, Charles; Riezman, Howard; Roux, Aurélien (2018) Lysophospholipids Facilitate COPII Vesicle Formation. Curr. Biol. 28 (12) 1950-1958.e6.
  • Perrin, Laurent; Loizides-Mangold, Ursula; Chanon, Stéphanie; Gobet, Cédric; Hulo, Nicolas; Isenegger, Laura; Weger, Benjamin D.; Migliavacca, Eugenia; Charpagne, Aline; Betts, James A.; Walhin, Jean-Philippe; Templeman, Iain; Stokes, Keith; Thompson, Dylan; Tsintzas, Kostas; Robert, Maud; Howald, Cedric; Riezman, Howard; Feige, Jerome N.; Karagounis, Leonidas G.; Johnston, Jonathan D.; Dermitzakis, Emmanouil T.; Gachon, Frédéric; Lefai, Etienne; Dibner, Charna (2018) Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. eLife 7 e34114.
  • Harayama, Takeshi; Riezman, Howard (2018) Understanding the diversity of membrane lipid composition. Nat. Rev. Mol. Cell Biol. 19 281-296.
  • Feng, Suihan; Harayama, Takeshi; Montessuit, Sylvie; David, Fabrice P. A.; Winssinger, Nicolas; Martinou, Jean-Claude; Riezman, Howard (2018) Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function. eLife 7 e34555.
  • Kawano, Shin; Tamura, Yasushi; Kojima, Rieko; Bala, Siqin; Asai, Eri; Michel, Agnès H.; Kornmann, Benoît; Riezman, Isabelle; Riezman, Howard; Sakae, Yoshitake; Okamoto, Yuko; Endo, Toshiya (2018) Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMES. J. Cell Biol. 217 (3) 959-974.
  • Shinde, Abhijit Babaji; Baboota, Ritesh Kumar; Denis, Simone; Loizides-Mangold, Ursula; Peeters, Annelies; Espeel, Marc; Malheiro, Ana Rita; Riezman, Howard; Vinckier, Stefan; Vaz, Frédéric M.; Brites, Pedro; Ferdinandusse, Sacha; Van Veldhoven, Paul P.; Baes, Myriam (2018) Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites. Mitochondrion 39 51-59.

2017

  • Guri, Yakir; Colombi, Marco; Dazert, Eva; Hindupur, Sravanth K.; Roszik, Jason; Moes, Suzette; Jenoe, Paul; Heim, Markus H.; Riezman, Isabelle; Riezman, Howard; Hall, Michael N. (2017) mTORC2 Promotes Tumorigenesis via Lipid Synthesis. Cancer Cell 32 (6) 807-823.e12.
  • Loizides-Mangold, Ursula; Perrin, Laurent; Vandereycken, Bart; Betts, James A.; Walhin, Jean-Philippe; Templeman, Iain; Chanon, Stéphanie; Weger, Benjamin D.; Durand, Christine; Robert, Maud; Paz Montoya, Jonathan; Moniatte, Marc; Karagounis, Leonidas G.; Johnston, Jonathan D.; Gachon, Frédéric; Lefai, Etienne; Riezman, Howard; Dibner, Charna (2017) Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro. Proc. Natl. Acad. Sci. USA 114 (41) E8565-E8574.
  • Dewhurst-Maridor, Gisèle; Abegg, Daniel; David, Fabrice P.A.; Rougemont, Jacques; Scott, Cameron C.; Adibekian, Alexander; Riezman, Howard; Drubin, David G. (2017) The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinate the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae. Mol. Biol. Cell 28 (20) 2637-2649.
  • Guerreiro, Joana F.; Mira, Nuno P.; Santos, Aline X. S.; Riezman, Howard; Sá-Correia, Isabel (2017) Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular Sphingolipids. Front. Microbiol. 8 01302.
  • Dorsaz, Stéphane; Snäka, Tiia; Favre-Godal, Quentin; Maudens, Pierre; Boulens, Nathalie; Furrer, Pascal; Ebrahimi, Samad Nejad; Hamburger, Matthias; Allémann, Eric; Gindro, Katia; Queiroz, Emerson Ferreira; Riezman, Howard; Wolfender, Jean-Luc; Sanglard, Dominique (2017) Identification and mode of action of a plant natural product targeting human fungal pathogens. Antimicrob. Agents Chemother. 61 e00829-17.
  • Harayama, Takeshi; Riezman, Howard (2017) Detection of genome-edited mutant clones by a simple competition-based PCR method. PLoS ONE 12 (6) e0179165.
  • Capasso, Serena; Sticco, Lucia; Rizzo, Riccardo; Pirozzi, Marinella; Russo, Domenico; Dathan, Nina A; Campelo, Felix; van Galen, Josse; Hölttä-Vuori, Maarit; Turacchio, Gabriele; Hausser, Angelika; Malhotra, Vivek; Riezman, Isabelle; Riezman, Howard; Ikonen, Elina; Luberto, Chiara; Parashuraman, Seetharaman; Luini, Alberto; D'Angelo, Giovanni (2017) Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi network. EMBO J. 36 (12) 1736-1754.
  • Hannich, J. Thomas; Mellal, Denia; Feng, Suihan; Zumbuehl, Andreas; Riezman, Howard (2017) Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans. Chem. Sci. 8 (5) 3676-3686.
  • Zimmermann, Christine; Santos, Aline; Gable, Kenneth; Epstein, Sharon; Gururaj, Charulatha; Chymkowitch, Pierre; Pultz, Dennis; Rødkær, Steven V.; Clay, Lorena; Bjørås, Magnar; Barral, Yves; Chang, Amy; Færgeman, Nils J.; Dunn, Teresa M.; Riezman, Howard; Enserink, Jorrit M. (2017) Correction: TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy. Cell Rep. 18 (8) 2073-2074.
  • Lovric, Svjetlana; Goncalves, Sara; Gee, Heon Yung; Oskouian, Babak; Srinivas, Honnappa; Choi, Won-Il; Shril, Shirlee; Ashraf, Shazia; Tan, Weizhen; Rao, Jia; Airik, Merlin; Schapiro, David; Braun, Daniela A.; Sadowski, Carolin E.; Widmeier, Eugen; Jobst-Schwan, Tilman; Schmidt, Johanna Magdalena; Girik, Vladimir; Capitani, Guido; Suh, Jung H.; Lachaussée, Noëlle; Arrondel, Christelle; Patat, Julie; Gribouval, Olivier; Furlano, Monica; Boyer, Olivia; Schmitt, Alain; Vuiblet, Vincent; Hashmi, Seema; Wilcken, Rainer; Bernier, Francois P.; Innes, A. Micheil; Parboosingh, Jillian S.; Lamont, Ryan E.; Midgley, Julian P.; Wright, Nicola; Majewski, Jacek; Zenker, Martin; Schaefer, Franz; Kuss, Navina; Greil, Johann; Giese, Thomas; Schwarz, Klaus; Catheline, Vilain; Schanze, Denny; Franke, Ingolf; Sznajer, Yves; Truant, Anne S.; Adams, Brigitte; Désir, Julie; Biemann, Ronald; Pei, York; Ars, Elisabet; Lloberas, Nuria; Madrid, Alvaro; Dharnidharka, Vikas R.; Connolly, Anne M.; Willing, Marcia C.; Cooper, Megan A.; Lifton, Richard P.; Simons, Matias; Riezman, Howard; Antignac, Corinne; Saba, Julie D.; Hildebrandt, Friedhelm (2017) Mutations in sphingosine-1-phosphase lyase cause nephrosis with ichthyosis and adrenal insufficiency. J. Clin. Invest. 127 (3) 912-928.

2016

  • Megyeri, Márton; Riezman, Howard; Schuldiner, Maya; Futerman, Anthony H. (2016) Making Sense of the Yeast Sphingolipid Pathway. J. Mol. Biol. 428 (24 Part A) 4765-4775.
  • Sikorska, Natalia; Lemus, Leticia; Aguilera-Romero, Auxiliadora; Manzano-Lopez, Javier; Riezman, Howard; Muñiz, Manuel; Goder, Veit (2016) Limited ER quality control for GPI-anchored proteins. J. Cell Biol. 269 (6) 19695-704.
  • Savoglidis, Georgios; da Silveira dos Santos, Aline Xavier; Riezman, Isabelle; Angelino, Paolo; Riezman, Howard; Hatzimanikatis, Vassily (2016) A method for analysis and design of metabolism using metabolomics data and kinetic models: application on lipidomics using a novel kinetic model of sphingolipid metabolism. Metab. Eng. 37 46-62.
  • Garcia, Alba Alfonso; Pfisterer, Simon G.; Riezman, Howard; Ikonen, Elina; Potma, Eric O. (2016) D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage. J. Biomed. Opt. 21 (6) 061003.
  • Muñiz, Manuel; Riezman, Howard (2016) Trafficking of glycosylphosphatidyl inositol anchored proteins from the endoplasmic reticulum to the cell surface. J. Lipid Res. 57 352-360.

2015

  • Höglinger, Doris; Haberkant, Per; Aguilera-Romero, Auxiliadora; Riezman, Howard; Porter, Forbes D.; Platt, Frances M.; Galione, Antony; Schultz, Carsten (2015) Intracellular sphingosine releases calcium from lysosomes. eLife 4 e10616.
  • Blom, Tomas; Li, Shiqian; Dichlberger, Andrea; Bäck, Nils; Kim, Young Ah; Loizides-Mangold, Ursula; Riezman, Howard; Bittman, Robert; Ikonen, Elina (2015) LAPTM4B facilitates late endosomal ceramide export to control cell death pathways. Nat. Chem. Biol. 11 (10) 799-806.
  • Frechin, Mathieu; Stoeger, Thomas; Daetwyler, Stephan; Gehin, Charlotte; Battich, Nico; Damm, Eva-Maria; Stergiou, Lilli; Riezman, Howard; Pelkmans, Lucas (2015) Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour. Nature 523 (7558) 88-91.
  • Aimo, Lucila; Liechti, Robin; Nouspikel, Nevila; Niknejad, Anne; Gleizes, Anne; Gotz, Lou; Kuznetsov, Dmitry; David, Fabrice P. A.; van der Gout, Gisou; Riezman, Howard; Bougueleret, Lydie; Xenarios, Ioannis; Bridge, Alan (2015) The SwissLipids knowledgebase for lipid biology. Bioinformatics 31 (17) 2860-2866.
  • Suresh, Harsha Garadi; da Silveira dos Santos, Aline Xavier; Kukulski, Wanda; Tyedmers, Jens; Riezman, Howard; Bukau, Bernd; Mogk, Axel (2015) Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae. Mol. Biol. Cell 26 (9) 1601-1615.
  • Manzano-Lopez, Javier; Perez-Linero, Ana M.; Aguilera-Romero, Auxiliadora; Martin, Maria E.; Okano, Tatsuki; Silva, Daniel Varon; Seeberger, Peter H.; Riezman, Howard; Funato, Kouichi; Goder, Veit; Wellinger, Ralf E.; Muñiz, Manuel (2015) COPII Coat Composition Is Actively Regulated by Luminal Cargo Maturation. Curr. Biol. 25 (2) 152-162.
  • Wilson-Zbinden, Caroline; dos Santos, Aline Xavier da Silveira; Stoffel-Studer, Ingrid; van der Vaart, Aniek; Hofmann, Kay; Reggiori, Fulvio; Riezman, Howard; Kraft, Claudine; Peter, Matthias (2015) Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiae. Genetics 199 (2) 475-485.

2014

  • Loizides-Mangold, Ursula; Clément, Sophie; Alfonso-Garcia, Alba; Branche, Emilie; Conzelmann, Stéphanie; Parisot, Clotilde; Potma, Eric O.; Riezman, Howard; Negro, Francesco; Jhaveri, Ravi (2014) HCV 3a Core Protein Increases Lipid Droplet Cholesteryl Ester Content via a Mechanism Dependent on Sphingolipid Biosynthesis. PLoS ONE 9 (12) e115309.
  • da Silveira dos Santos, Aline Xavier; Riezman, Isabelle; Aguilera-Romero, Maria-Auxiliadora; David, Fabrice; Piccolis, Manuele; Loewith, Robbie; Schaad, Olivier; Riezman, Howard (2014) Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis. Mol. Biol. Cell 25 (20) 3234-3246.
  • Lakshminarayanan, Rajamani; Liu, Shouping; Li, Jianguo; Nandhakumar, Muruganantham; Aung, Thet Tun; Goh, Eunice; Chang, Jamie Ya Ting; Saraswathi, Padhmanaban; Tang, Charles; Safie, Siti Radiah Binte; Lin, Lim Yih; Riezman, Howard; Lei, Zhou; Verma, Chandra S.; Beuerman, Roger W.; Khan, Rizwan H. (2014) Synthetic Multivalent Antifungal Peptides Effective against Fungi. PLoS ONE 9 (2) e87730.
  • Prifti, Efthymia; Reymond, Luc; Umebayashi, Miwa; Hovius, Ruud; Riezman, Howard; Johnsson, Kai (2014) A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red. ACS Chem. Biol. 9 (3) 606-612.
  • Kajiwara, Kentaro; Ikeda, Atsuko; Aguilera-Romero, Auxiliadora; Castillon, Guillaume A.; Kagiwada, Satoshi; Hanada, Kentaro; Riezman, Howard; Muniz, Manuel; Funato, Kouichi (2014) Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast. J. Cell Sci. 127 (2) 376-387.
  • Aguilera-Romero, Auxiliadora; Gehin, Charlotte; Riezman, Howard (2014) Sphingolipid homeostasis in the web of metabolic routes. Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 1841 (5) 647-656.

2013

  • Cohen, Yifat; Megyeri, Márton; Chen, Oscar C. W.; Condomitti, Giuseppe; Riezman, Isabelle; Loizides-Mangold, Ursula; Abdul-Sada, Alaa; Rimon, Nitzan; Riezman, Howard; Platt, Frances M.; Futerman, Anthony H.; Schuldiner, Maya; Michnick, Stephen W. (2013) The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic Reticulum. PLoS ONE 8 (12) e85519.
  • Zimmermann, Christine; Santos, Aline; Gable, Kenneth; Epstein, Sharon; Gururaj, Charulatha; Chymkowitch, Pierre; Pultz, Dennis; Rødkær, Steven V.; Clay, Lorena; Bjørås, Magnar; Barral, Yves; Chang, Amy; Færgeman, Nils J.; Dunn, Teresa M.; Riezman, Howard; Enserink, Jorrit M. (2013) TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy. Cell Rep. 5 (4) 1036-1046.
  • Ding, Jun; Loizides-Mangold, Ursula; Rando, Gianpaolo; Zoete, Vincent; Michielin, Olivier; Reddy, Janardan K.; Wahli, Walter; Riezman, Howard; Thorens, Bernard (2013) The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids. Cell Rep. 5 (1) 248-258.
  • Lindberg, Lina; Santos, Aline XS.; Riezman, Howard; Olsson, Lisbeth; Bettiga, Maurizio; Oresic, Matej (2013) Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid Stress. PLoS ONE 8 (9) e73936.
  • Gehin, Charlotte; Montenegro, Javier; Bang, Eun-Kyoung; Cajaraville, Ana; Takayama, Shota; Hirose, Hisaaki; Futaki, Shiroh; Matile, Stefan; Riezman, Howard (2013) Dynamic Amphiphile Libraries to Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts. J. Am. Chem. Soc. 135 (25) 9295-9298.
  • Epstein, Sharon; Riezman, Howard (2013) Sphingolipid signaling in yeast: potential implications for understanding disease. Front. Biosci., Elite Ed. 5 97-108.

2012

  • Santos, Aline X. S.; Riezman, Howard (2012) Yeast as a model system for studying lipid homeostasis and function. FEBS Lett. 586 (18) 2858-2867.
  • Jarmoszewicz, Katarzyna; Łukasiak, Katarzyna; Riezman, Howard; Kaminska, Joanna; Polymenis, Michael (2012) Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI Mutants. PLoS ONE 7 (6) e39582.
  • Loizides-Mangold, Ursula; David, Fabrice P. A.; Nesatyy, Victor J.; Kinoshita, Taroh; Riezman, Howard (2012) Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels. J. Lipid Res. 53 (8) 1522-1534.
  • Epstein, Sharon; Castillon, Guillaume A.; Qin, Yongmei; Riezman, Howard (2012) An essential function of sphingolipids in yeast cell division. Mol. Microbiol. 84 (6) 1018-1032.
  • Berchtold, Doris; Piccolis, Manuele; Chiaruttini, Nicolas; Riezman, Isabelle; Riezman, Howard; Roux, Aurélien; Walther, Tobias C.; Loewith, Robbie (2012) Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. Nat. Cell Biol. 14 (5) 542-547.
  • Alonso Doval, David; Fin, Andrea; Takahashi-Umebayashi, Miwa; Riezman, Howard; Roux, Aurelien; Sakai, Naomi; Matile, Stefan (2012) Amphiphilic Dynamic NDI and PDI Probes:  Imaging Microdomains in Giant Unilamellar Vesicles. Org. Biomol. Chem. 10 (30) 6087-6093.
  • Epstein, Sharon; Kirkpatrick, Clare L.; Castillon, Guillaume A.; Muniz, Manuel; Riezman, Isabelle; David, Fabrice P. A.; Wollheim, Claes B.; Riezman, Howard (2012) Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells. J. Lipid Res. 53 (3) 412-420.
  • Jennemann, Richard; Rabionet, Mariona; Gorgas, Karin; Epstein, Sharon; Dalpke, Alexander; Rothermel, Ulrike; Bayerle, Aline; van der Hoeven, Franciscus; Imgrund, Silke; Kirsch, Joachim; Nickel, Walter; Willecke, Klaus; Riezman, Howard; Grone, Hermann-Josef; Sandhoff, Roger (2012) Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum. Mol. Genet. 21 (3) 586-608.

2011

  • Alvarez-Vasquez, Fernando; Riezman, Howard; Hannun, Yusuf A.; Voit, Eberhard O.; Zhang, Zhengguang (2011) Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiae. PLoS ONE 6 (12) e28344.
  • Takahashi-Umebayashi, Miwa; Pineau, Ludovic; Hannich, Thomas; Zumbuehl, Andreas; Alonso Doval, David; Matile, Stefan; Heinis, Christian; Turcatti, Gerardo; Loewith, Robbie; Roux, Aurelien; Reymond, Luc; Johnsson, Kai; Riezman, Howard (2011) Chemical Biology Approaches to Membrane Homeostasis and Function. CHIMIA 65 (11) 849-852.
  • Montenegro, Javier; Gehin, Charlotte; Bang, Eun-Kyoung; Fin, Andrea; Alonso Doval, David; Riezman, Howard; Sakai, Naomi; Matile, Stefan (2011) Conceptually New Entries into Cells. CHIMIA 65 (11) 853-858.
  • Sturzenegger, Susi; Johnsson, Kai; Riezman, Howard (2011) NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland. CHIMIA 65 (11) 832-834.
  • Lissina, Elena; Young, Brian; Urbanus, Malene L.; Guan, Xue Li; Lowenson, Jonathan; Hoon, Shawn; Baryshnikova, Anastasia; Riezman, Isabelle; Michaut, Magali; Riezman, Howard; Cowen, Leah E.; Wenk, Markus R.; Clarke, Steven G.; Giaever, Guri; Nislow, Corey; Cooper, Sara J. (2011) A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis. PLoS Genet. 7 (10) e1002332.
  • Ternes, Philipp; Feussner, Kirstin; Werner, Stephanie; Lerche, Jennifer; Iven, Tim; Heilmann, Ingo; Riezman, Howard; Feussner, Ivo (2011) Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana. New Phytol. 192 (4) 841-854.
  • Fujita, Morihisa; Watanabe, Reika; Jaensch, Nina; Romanova-Michaelides, Maria; Satoh, Tadashi; Kato, Masaki; Riezman, Howard; Yamaguchi, Yoshiki; Maeda, Yusuke; Kinoshita, Taroh (2011) Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI. J. Cell Biol. 194 (1) 61-75.
  • Souza, Cleiton M.; Schwabe, Tatjana M.E.; Pichler, Harald; Ploier, Birgit; Leitner, Erich; Guan, Xue Li; Wenk, Markus R.; Riezman, Isabelle; Riezman, Howard (2011) A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance. Metab. Eng. 13 (5) 555-569.
  • Castillon, Guillaume A.; Aguilera-Romero, Auxiliadora; Manzano-Lopez, Javier; Epstein, Sharon; Kajiwara, Kentaro; Funato, Kouichi; Watanabe, Reika; Riezman, Howard; Muniz, Manuel (2011) The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling. Mol. Biol. Cell 22 (16) 2924-2936.
  • Hannich, J. Thomas; Umebayashi, Kyohei; Riezman, Howard (2011) Distribution and Functions of Sterols and Sphingolipids. Cold Spring Harbor Perspect. Biol. 3 (5) a004762.
  • Shivapurkar, Rupali; Souza, Cleiton M.; Jeannerat, Damien; Riezman, Howard (2011) An Efficient Method for the Production of Isotopically Enriched Cholesterol for NMR. J. Lipid Res. 52 (5) 1062-1065.
  • Ternes, Philipp; Wobbe, Tobias; Schwarz, Marnie; Albrecht, Sandra; Feussner, Kirstin; Riezman, Isabelle; Cregg, James M.; Heinz, Ernst; Riezman, Howard; Feussner, Ivo; Warnecke, Dirk (2011) Two Pathways of Sphingolipid Biosynthesis Are Separated in the Yeast Pichia pastoris. J. Biol. Chem. 286 (13) 11401-11414.

2010

2009

  • González-Gaitán, Marcos; Gruenberg, Jean; Halazonetis, Thanos; Laemmli, Ulrich K.; Matter, Jean-Marc; Riezman, Howard; Schaad, Olivier; Soldati, Thierry; Watanabe, Reika (2009) The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization. CHIMIA 63 (12) 830-834.
  • Deshusses, Jacques; Riezman, Howard (2009) History of Biochemistry at the University of Geneva: From the Boulevard des Philosophes to Quai Ernest-Ansermet. CHIMIA 63 (12) 826-829.
  • Castillon, Guillaume A. Riezman, Howard (2009) Transport of GPI-Anchored Proteins: Connections to Sphingolipid and Sterol Transport. Glycosylphosphatidylinositol (GPI) Anchoring of Proteins Vol. 26 (Chapter 13)Ed. Menon, Anant Kumar Kinoshita, Taroh Orlean, Peter Tamanoi, FuyuhikoThe Enzymes. Elsevier. 269-288.
  • Hannich, J. Thomas; Entchev, Eugeni V.; Mende, Fanny; Boytchev, Hristio; Martin, René; Zagoriy, Vyacheslav; Theumer, Gabriele; Riezman, Isabelle; Riezman, Howard; Knölker, Hans-Joachim; Kurzchalia, Teymuras V. (2009) Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans. Dev. Cell 16 (6) 833-843.
  • Menuz, Vincent; Howell, Kate S.; Gentina, Sébastien; Epstein, Sharon; Riezman, Isabelle; Fornallaz-Mulhauser, Monique; Hengartner, Michael O.; Gomez, Marie; Riezman, Howard; Martinou, Jean-Claude (2009) Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase. Science 324 (5925) 381-384.
  • Guan, Xue Li; Souza, Cleiton M.; Pichler, Harald; Dewhurst, Gisèle; Schaad, Olivier; Kajiwara, Kentaro; Wakabayashi, Hirotomo; Ivanova, Tania; Castillon, Guillaume A.; Piccolis, Manuele; Abe, Fumiyoshi; Loewith, Robbie; Funato, Kouichi; Wenk, Markus R.; Riezman, Howard (2009) Functional Interactions between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology. Mol. Biol. Cell 20 (7) 2083-2095.
  • Castillon, Guillaume A.; Watanabe, Reika; Taylor, Marcia; Schwabe, Tatjana M. E.; Riezman, Howard (2009) Concentration of GPI-Anchored Proteins upon ER Exit in Yeast. Traffic 10 (2) 186-200.

2008

  • Watanabe, Reika; Castillon, Guillaume A.; Meury, Anja; Riezman, Howard (2008) The presence of an ER exit signal determines the protein sorting upon ER exit in yeast. Biochem. J. 414 (2) 237-245.
  • Mukhopadhyay, Debdyuti; Howell, Kate S.; Riezman, Howard; Capitani, Guido (2008) Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in Vitro. J. Biol. Chem. 283 (29) 20159-20169.
  • Idrissi, Fatima-Zahra; Grötsch, Helga; Fernández-Golbano, Isabel M.; Presciatto-Baschong, Cristina; Riezman, Howard; Geli, María-Isabel (2008) Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane. J. Cell Biol. 180 (6) 1219-1232.
  • Kajiwara, Kentaro; Watanabe, Reika; Pichler, Harald; Ihara, Kensuke; Murakami, Suguru; Riezman, Howard; Funato, Kouichi (2008) Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum. Mol. Biol. Cell 19 (5) 2069-2082.
  • Aguilera-Romero, Auxiliadora; Kaminska, Joanna; Spang, Anne; Riezman, Howard; Muñiz, Manuel (2008) The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus. J. Cell Biol. 13 (4) 5539-720.
  • te Welscher, Yvonne M.; ten Napel, Hendrik H.; Balagué, Miriam Masià; Souza, Cleiton M.; Riezman, Howard; de Kruijff, Ben; Breukink, Eefjan (2008) Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the Membrane. J. Biol. Chem. 283 (10) 6393-6401.

2007

  • Riezman, Howard (2007) The Long and Short of Fatty Acid Synthesis. Cell 130 (4) 587-588.
  • Urban, Jörg; Soulard, Alexandre; Huber, Alexandre; Lippman, Soyeon; Mukhopadhyay, Debdyuti; Deloche, Olivier; Wanke, Valeria; Anrather, Dorothea; Ammerer, Gustav; Riezman, Howard; Broach, James R.; De Virgilio, Claudio; Hall, Michael N.; Loewith, Robbie (2007) Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae. Molecular Cell 26 (5) 663-674.
  • Mukhopadhyay, Debdyuti; Riezman, Howard (2007) Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling. Science 315 (5809) 201-205.

2006

  • Kageyama-Yahara, Natsuko; Riezman, Howard (2006) Transmembrane topology of ceramide synthase in yeast. Biochem. J. 398 (3) 585-593.
  • Riezman, Howard (2006) Organization and functions of sphingolipid biosynthesis in yeast. Biochem. Soc. Trans. 34 (3) 367-369.
  • Grosshans, Bianka L.; Grötsch, Helga; Mukhopadhyay, Debdyuti; Fernandez, Isabel M.; Pfannstiel, Jens; Idrissi, Fatima-Zahra; Lechner, Johannes; Riezman, Howard; Geli, M. Isabel (2006) TEDS Site Phosphorylation of the Yeast Myosins I Is Required for Ligand-induced but Not for Constitutive Endocytosis of the G Protein-coupled Receptor Ste2p. J. Biol. Chem. 281 (16) 11104-11114.
  • Meier, Karsten D.; Deloche, Olivier; Kajiwara, Kentaro; Funato, Kouichi; Riezman, Howard (2006) Sphingoid Base Is Required for Translation Initiation during Heat Stress in Saccharomyces cerevisiae. Mol. Biol. Cell 17 (3) 1164-1175.

2004

2003

  • Schaerer-Brodbeck, Claudia; Riezman, Howard (2003) Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast. FEMS Yeast Res. 4 (1) 37-49.
  • Pomorski, Thomas; Lombardi, Ruben; Riezman, Howard; Devaux, Philippe F.; van Meer, Gerrit; Holthuis, Joost C. M.; Bonifacino, Juan (2003) Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in Endocytosis. Mol. Biol. Cell 14 (3) 1240-1254.

2002

2001

  • Muñiz, Manuel; Morsomme, Pierre; Riezman, Howard (2001) Protein Sorting upon Exit from the Endoplasmic Reticulum. Cell 104 (2) 313-320.

2000

  • Schaerer-Brodbeck, Claudia; Riezman, Howard (2000) Interdependence of Filamentous Actin and Microtubules for Asymmetric Cell Division. Biol. Chem. 381 (9-10) 815-825.