Publications
2020
- Lehal, Rajwinder; Zaric, Jelena; Vigolo, Michele; Urech, Charlotte; Frismantas, Viktoras; Zangger, Nadine; Cao, Linlin; Berger, Adeline; Chicote, Irene; Loubéry, Sylvain; Choi, Sung Hee; Koch, Ute; Blacklow, Stephen C.; Palmer, Hector G.; Bornhauser, Beat; González-Gaitán, Marcos; Arsenijevic, Yvan; Zoete, Vincent; Aster, Jon C.; Bourquin, Jean-Pierre; Radtke, Freddy (2020) Pharmacological disruption of the Notch transcription factor complex. Proc. Natl. Acad. Sci. USA 117 (28) 16292-16301.
- Castanon, Irinka; Hannich, Joerg Thomas; Abrami, Laurence; Huber, Florian; Dubois, Marine; Müller, Markus; van der Goot, F. Gisou; Gonzalez-Gaitan, Marcos (2020) Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish. Nat. Commun. 11 art. num 3317.
- Bürgi, Jérôme; Abrami, Laurence; Castanon, Irinka; Abriata, Luciano Andres; Kunz, Beatrice; Yan, Shixu Emili; Lera, Manuel; Unger, Sheila; Superti-Furga, Andrea; Peraro, Matteo Dal; Gonzalez Gaitan, Marcos; van der Goot, Francoise Gisou (2020) Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis. Dev. Cell 53 (4) 418-430.e4.
2019
- Manenschijn, Hetty E.; Picco, Andrea; Mund, Markus; Rivier-Cordey, Anne-Sophie; Ries, Jonas; Kaksonen, Marko (2019) Type-I myosins promote actin polymerization to drive membrane bending in endocytosis. eLife 8 e44215.
2018
- Mund, Markus; van der Beek, Johannes Albertus; Deschamps, Joran; Dmitrieff, Serge; Hoess, Philipp; Monster, Jooske Louise; Picco, Andrea; Nédélec, François; Kaksonen, Marko; Ries, Jonas (2018) Systematic Nanoscale Analysis of Endocytosis Links Efficient Vesicle Formation to Patterned Actin Nucleation. Cell 174 (4) 884-896.e17.
- Picco, Andrea; Kaksonen, Marko (2018) Quantitative imaging of clathrin-?mediated endocytosis. Curr. Opin. Cell Biol. 53 105-110.
- Picco, Andrea; Kukulski, Wanda; Manenschijn, Hetty E.; Specht, Tanja; Briggs, John A. G.; Kaksonen, Marko (2018) The contributions of the actin machinery to endocytic membrane bending and vesicle formation. Mol. Biol. Cell 29 (11) 1346-1358.
- Picco, Andrea; Kukulski, Wanda; Manenschijn, Hetty E.; Specht, Tanja; Briggs, John A. G.; Kaksonen, Marko (2018) The contributions of the actin machinery to endocytic membrane bending and vesicle formation. Mol. Biol. Cell 29 (11) 1346-1358.
- Kaksonen, Marko; Roux, Aurélien (2018) Mechanisms of clathrin-mediated endocytosis. Nat. Rev. Mol. Cell Biol. 19 313-326.
- Garcia-Alai, Maria M.; Heidemann, Johannes; Skruzny, Michal; Gieras, Anna; Mertens, Haydyn D. T.; Svergun, Dmitri I.; Kaksonen, Marko; Uetrecht, Charlotte; Meijers, Rob (2018) Epsin and Sla2 form assemblies through phospholipid interfaces. Nat. Commun. 9 (1) 328.
2017
- Picco, Andrea; Irastorza-Azcarate, Ibai; Specht, Tanja; Böke, Dominik; Pazos, Irene; Rivier-Cordey, Anne-Sophie; Devos, Damien P.; Kaksonen, Marko; Gallego, Oriol (2017) The In Vivo Architecture of the Exocyst Provides Structural Basis for Exocytosis. Cell 168 (3) 400-412.e18.
- Picco, A. Kaksonen, Marko (2017) Precise tracking of the dynamics of multiple proteins in endocytic events. Cell Polarity and Morphogenesis Volume 139 (Chapter 3)Ed. Thomas, LecuitMethods in Cell Biology. Academic Press. 51-68.
2016
- Kukulski, Wanda; Picco, Andrea; Specht, Tanja; Briggs, John A. G.; Kaksonen, Marko (2016) Clathrin modulates vesicle scission, but not invagination shape, in yeast endocytosis. eLife 5 e16036.
- Bertipaglia, Chiara; Schneider, Sarah; Jakobi, Arjen J.; Tarafder, Abul K.; Bykov, Yury S.; Picco, Andrea; Kukulski, Wanda; Kosinski, Jan; Hagen, Wim J. H.; Ravichandran, Arvind C.; Wilmanns, Matthias; Kaksonen, Marko; Briggs, John A. G.; Sachse, Carsten (2016) Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle. EMBO Rep. 17 (7) 1044-1060.
2015
- Avinoam, Ori; Schorb, Martin; Beese, Carsten J.; Briggs, John A. G.; Kaksonen, Marko (2015) Endocytic sites mature by continuous bending and remodeling of the clathrin coat. Science 348 (6241) 1369-1372.
- Skruzny, Michal; Desfosses, Ambroise; Prinz, Simone; Dodonova, Svetlana O.; Gieras, Anna; Uetrecht, Charlotte; Jakobi, Arjen J.; Abella, Marc; Hagen, Wim J.H.; Schulz, Joachim; Meijers, Rob; Rybin, Vladimir; Briggs, John A.G.; Sachse, Carsten; Kaksonen, Marko (2015) An Organized Co-assembly of Clathrin Adaptors Is Essential for Endocytosis. Dev. Cell 33 (2) 150-162.
- Picco, Andrea; Mund, Markus; Ries, Jonas; Nédélec, François; Kaksonen, Marko (2015) Visualizing the functional architecture of the endocytic machinery. eLife 4 e04535.
2014
- Boeke, Dominik; Trautmann, Susanne; Meurer, Matthias; Wachsmuth, Malte; Godlee, Camilla; Knop, Michael; Kaksonen, Marko (2014) Quantification of cytosolic interactions identifies Ede1 oligomers as key organizers of endocytosis. Mol. Syst. Biol. 10 (11) 756-756.
- Merrifield, Christien J.; Kaksonen, Marko (2014) Endocytic Accessory Factors and Regulation of Clathrin-Mediated Endocytosis. Cold Spring Harbor Perspect. Biol. 6 (11) a016733.
- Xiol, Jordi; Spinelli, Pietro; Laussmann, Maike A.; Homolka, David; Yang, Zhaolin; Cora, Elisa; Couté, Yohann; Conn, Simon; Kadlec, Jan; Sachidanandam, Ravi; Kaksonen, Marko; Cusack, Stephen; Ephrussi, Anne; Pillai, Ramesh S. (2014) RNA Clamping by Vasa Assembles a piRNA Amplifier Complex on Transposon Transcripts. Cell 157 (7) 1698-1711.
- Brach, Thorsten; Godlee, Camilla; Moeller-Hansen, Iben; Boeke, Dominik; Kaksonen, Marko (2014) The Initiation of Clathrin-Mediated Endocytosis Is Mechanistically Highly Flexible. Curr. Biol. 24 (5) 548-554.
2013
- Godlee, Camilla; Kaksonen, Marko (2013) From uncertain beginnings: Initiation mechanisms of clathrin-mediated endocytosis. The Journal of Cell Biology 104 (10) 3793-725.
- Maeda, Kenji; Anand, Kanchan; Chiapparino, Antonella; Kumar, Arun; Poletto, Mattia; Kaksonen, Marko; Gavin, Anne-Claude (2013) Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins. Nature 501 (7466) 257-261.
- Gallego, Oriol; Specht, Tanja; Brach, Thorsten; Kumar, Arun; Gavin, Anne-Claude; Kaksonen, Marko; Keen, James (2013) Detection and Characterization of Protein Interactions In Vivo by a Simple Live-Cell Imaging Method. PLoS ONE 8 (5) e62195.
2012
- Skruzny, Michal; Brach, Thorsten; Ciuffa, Rodolfo; Rybina, Sofia; Wachsmuth, Malte; Kaksonen, Marko (2012) Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis. Proc. Natl. Acad. Sci. U. S. A. 109 (38) E2533-E2542.
- Kukulski, Wanda; Schorb, Martin; Kaksonen, Marko; Briggs, John A.G. (2012) Plasma Membrane Reshaping during Endocytosis Is Revealed by Time-Resolved Electron Tomography. Cell 150 (3) 508-520.
- Kukulski, Wanda Schorb, Martin Welsch, Sonja Picco, Andrea Kaksonen, Marko Briggs, John A.G. (2012) Precise, Correlated Fluorescence Microscopy and Electron Tomography of Lowicryl Sections Using Fluorescent Fiducial Markers. Correlative Light and Electron Microscopy Volume 111 (Chapter 13)Ed. Müller-Reichert, Thomas Verkade, PaulMethods in Cell Biology. Elsevier. 235-257.
2011
- Brach, Thorsten; Specht, Tanja; Kaksonen, Marko (2011) Reassessment of the role of plasma membrane domains in the regulation of vesicular traffic in yeast. J. Cell Sci. 124 (3) 328-337.
- Kukulski, Wanda; Schorb, Martin; Welsch, Sonja; Picco, Andrea; Kaksonen, Marko; Briggs, John A.G. (2011) Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision. J. Cell Biol. 208 (1) 3-119.
2010
- Gallego, Oriol; Betts, Matthew J.; Gvozdenovic-Jeremic, Jelena; Maeda, Kenji; Matetzki, Christian; Aguilar-Gurrieri, Carmen; Beltran-Alvarez, Pedro; Bonn, Stefan; Fernández-Tornero, Carlos; Jensen, Lars Juhl; Kuhn, Michael; Trott, Jamie; Rybin, Vladimir; Müller, Christoph W.; Bork, Peer; Kaksonen, Marko; Russell, Robert B.; Gavin, Anne-Claude (2010) A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae. Mol. Syst. Biol. 6 (1) 430.
2008
- Kaksonen, Marko (2008) Taking apart the endocytic machinery. J. Cell Biol. 180 (6) 1059-1060.
2007
- Sun, Yidi; Carroll, Susheela; Kaksonen, Marko; Toshima, Junko Y.; Drubin, David G. (2007) PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization. J. Cell Biol. 177 (2) 355-367.
2006
- Kaksonen, Marko; Drubin, David G. (2006) PALM Reading: Seeing the Future of Cell Biology at Higher Resolution. Dev. Cell 11 (4) 438-439.
- Liu, Jian; Kaksonen, Marko; Drubin, David G.; Oster, George (2006) Endocytic vesicle scission by lipid phase boundary forces. Proc. Natl. Acad. Sci. USA 103 (27) 10277-10282.
- Kaksonen, Marko; Toret, Christopher P.; Drubin, David G. (2006) Harnessing actin dynamics for clathrin-mediated endocytosis. Nat. Rev. Mol. Cell Biol. 7 (6) 404-414.
- Toshima, Junko Y.; Toshima, Jiro; Kaksonen, Marko; Martin, Adam C.; King, David S.; Drubin, David G. (2006) Spatial dynamics of receptor-mediated endocytic trafficking in budding yeast revealed by using fluorescent α-factor derivatives. Proc. Natl. Acad. Sci. USA 103 (15) 5793-5798.
2005
- Kaksonen, Marko; Toret, Christopher P.; Drubin, David G. (2005) A Modular Design for the Clathrin- and Actin-Mediated Endocytosis Machinery. Cell 123 (2) 305-320.
- Drubin, David G. Kaksonen, Marko Toret, Christopher Sun, Yidi (2005) Cytoskeletal Networks and Pathways Involved in Endocytosis. Signalling Networks in Cell Shape and Motility 269Ed. Bock, Gregory Goode, JamieNovartis Foundation Symposium. John Wiley & Sons, Ltd. (Chichester, UK.). 35-46.
- Martin, Adam C.; Xu, Xiao-Ping; Rouiller, Isabelle; Kaksonen, Marko; Sun, Yidi; Belmont, Lisa; Volkmann, Niels; Hanein, Dorit; Welch, Matthew; Drubin, David G. (2005) Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function. J. Cell Biol. 168 (2) 315-328.
- Sun, Yidi; Kaksonen, Marko; Madden, David T.; Schekman, Randy; Drubin, David G. (2005) Interaction of Sla2p's ANTH Domain with PtdIns(4,5)P2 Is Important for Actin-dependent Endocytic Internalization. Mol. Biol. Cell 16 (2) 717-730.
2003
- Kaksonen, Marko; Sun, Yidi; Drubin, David G. (2003) A Pathway for Association of Receptors, Adaptors, and Actin during Endocytic Internalization. Cell 115 (4) 475-487.
- Sekiya-Kawasaki, Mariko; Groen, Aaron Chris; Cope, M. Jamie T. V.; Kaksonen, Marko; Watson, Hadiya A.; Zhang, Chao; Shokat, Kevan M.; Wendland, Beverly; McDonald, Kent L.; McCaffery, J. Michael; Drubin, David G. (2003) Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis. J. Cell Biol. 162 (5) 765-772.
2002
- Kaksonen, Marko; Pavlov, Ivan; Võikar, Vootele; Lauri, Sari E.; Hienola, Anni; Riekki, Ruusu; Lakso, Merja; Taira, Tomi; Rauvala, Heikki (2002) Syndecan-3-Deficient Mice Exhibit Enhanced LTP and Impaired Hippocampus-Dependent Memory. Mol. Cell. Neurosci. 21 (1) 158-172.
- Pavlov, Ivan; Võikar, Vootele; Kaksonen, Marko; Lauri, Sari E.; Hienola, Anni; Taira, Tomi; Rauvala, Heikki (2002) Role of Heparin-Binding Growth-Associated Molecule (HB-GAM) in Hippocampal LTP and Spatial Learning Revealed by Studies on Overexpressing and Knockout Mice. Mol. Cell. Neurosci. 20 (2) 330-342.
2001
- Reizes, Ofer; Lincecum, John; Wang, Zihua; Goldberger, Olga; Huang, Li; Kaksonen, Marko; Ahima, Rexford; Hinkes, Michael T.; Barsh, Gregory S.; Rauvala, Heikki; Bernfield, Merton (2001) Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3. Cell 106 (1) 105-116.
2000
- Kaksonen, Marko; Peng, H. Benjamin; Rauvala, Heikki (2000) Association of cortactin with dynamic actin in lamellipodia and on endosomal vesicles. J. Cell Sci. 113 (24) 4421-4426.
- Rauvala, Heikki; Huttunen, Henri J.; Fages, Carole; Kaksonen, Marko; Kinnunen, Tarja; Imai, Shinji; Raulo, Erkki; Kilpeläinen, Ilkka (2000) Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility. Matrix Biol. 19 (5) 377-387.
- Kilpelainen, Ilkka; Kaksonen, Marko; Kinnunen, Tarja; Avikainen, Hanna; Fath, Melissa; Linhardt, Robert J.; Raulo, Erkki; Rauvala, Heikki (2000) Heparin-binding Growth-associated Molecule Contains Two Heparin-binding beta -Sheet Domains That Are Homologous to the Thrombospondin Type I Repeat. J. Biol. Chem. 275 (18) 13564-13570.
1999
- Kinnunen, Anu; Niemi, Maria; Kinnunen, Tarja; Kaksonen, Marko; Nolo, Riitta; Rauvala, Heikki (1999) Heparan sulphate and HB-GAM (heparin-binding rowth-associated molecule) in the development of the thalamocortical pathway of rat brain. Eur. J. Neurosci. 11 (2) 491-502.
1998
- Imai, Shinji; Kaksonen, Marko; Raulo, Erkki; Kinnunen, Tarja; Fages, Carole; Meng, Xiaojuan; Lakso, Merja; Rauvala, Heikki (1998) Osteoblast Recruitment and Bone Formation Enhanced by Cell Matrix-associated Heparin-binding Growth-associated Molecule (HB-GAM). J. Cell Biol. 143 (4) 1113-1128.
- Fages, Carole; Kaksonen, Marko; Kinnunen, Tarja; Punnonen, Eeva-Liisa; Rauvala, Heikki (1998) Regulation of mRNA localization by transmembrane signalling: local interaction of HB-GAM (heparin-binding growth-associated molecule) with the cell surface localizes beta-actin mRNA. J. Cell Sci. 111 (20) 3073-3080.
- Kinnunen, Tarja; Kaksonen, Marko; Saarinen, Juhani; Kalkkinen, Nisse; Peng, H. Benjamin; Rauvala, H. Benjamin (1998) Cortactin-Src Kinase Signaling Pathway Is Involved in N-syndecan-dependent Neurite Outgrowth. J. Biol. Chem. 273 (17) 10702-10708.
- Kinnunen, Anu; Kinnunen, Tarja; Kaksonen, Marko; Nolo, Riitta; Panula, Pertti; Rauvala, Heikki (1998) N-Syndecan and HB-GAM (Heparin-Binding Growth-Associated Molecule) associate with early axonal tracts in the rat brain. Eur. J. Neurosci. 10 (2) 635-648.
1996
- Nolo, Riitta; Kaksonen, Marko; Rauvala, Heikki (1996) Developmentally Regulated Neurite Outgrowth Response from Dorsal Root Ganglion Neurons to Heparin-binding Growth-associated Molecule (HB-GAM) and the Expression of HB-GAM in the Targets of the Developing Dorsal Root Ganglion Neurites. Eur. J. Neurosci. 8 (8) 1658-1665.
1995
- Nolo, Riitta; Kaksonen, Marko; Raulo, Erkki; Rauvala, Heikki (1995) Co-expression of heparin-binding growth-associated molecule (HB-GAM) and N-syndecan (syndecan-3) in developing rat brain. Neurosci. Lett. 191 (1-2) 39-42.