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  2. Chiaruttini N, Roux A. Dynamic and elastic shape transitions in curved ESCRT-III filaments. Curr Opin Cell Biol.2017 Aug;47:126-135.
  3. Shydlovskyi S, Zienert AY, Ince S, Dovengerds C, Hohendahl A, Dargazanli JM, Blum A, Günther SD, Kladt N, Stürzl M, Schauss AC, Kutsch M, Roux A, Praefcke GJK, Herrmann C. Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1. Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5559-E5568.
  4. Roux A, Loewith R. Tensing Up for Lipid Droplet Formation. Dev Cell. 2017 Jun 19;41(6):571-572.
  5. Mierzwa BE*, Chiaruttini N*, Redondo-Morata L*, von Filseck JM, König J, Larios J, Poser I, Müller-Reichert T, Scheuring S, Roux A*, Gerlich DW*. Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis. Nat Cell Biol. 2017 Jul;19(7):787-798. News&Views in NCB.
  6. Daumke O, Roux A. Mitochondrial Homeostasis: How Do Dimers of Mitofusins Mediate Mitochondrial Fusion? Curr Biol. 2017 May 8;27(9):R353-R356.
  7. Colom A, Redondo-Morata L, Chiaruttini N, Roux A*, Scheuring S*. Dynamic remodeling of the dynamin helix during membrane constriction. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5449-5454.
  8. Cardenal-Muñoz E, Arafah S, López-Jiménez AT, Kicka S, Falaise A, Bach F, Schaad O, King JS, Hagedorn M, Soldati T. (2017) Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner. PLoS Pathog. 13(4):e1006344.
  9. Barisch C, Soldati T. (2017) Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions. PLoS Pathog. 13(1):e1006095.
  10. Leiba J, Sabra A, Bodinier R, Marchetti A, Lima WC, Melotti A, Perrin J, Burdet F, Pagni M, Soldati T, Lelong E, Cosson P. (2017) Vps13F links bacterial recognition and intracellular killing in Dictyostelium. Cell Microbiol. doi: 10.1111/cmi.12722
  11. Mesquita, A., Cardenal-Muñoz, E., Dominguez, E., Muñoz-Braceras, S., Nuñez-Corcuera, B., Philips, B.A., Tábara, L.C., Xiong, Q., Coria, R., Eichinger, L., Golstein, P., King, J.S., Soldati, T., Vincent, O. and Escalante, R. (2017) Autophagy in Dictyostelium: mechanisms, regulation and disease in a simple biomedical model Autophagy. 13(1):24-40


  1. Soleimanpour S, Colom A, Derivery E, Gonzalez-Gaitan M, Roux A, Sakai N, Matile S. Headgroup engineering in mechanosensitive membrane probes. Chem Commun (Camb). 2016 Dec 13;52(100):14450-14453.
  2. Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, Merrifield C, Pollard TD, Robinson PJ, Roux A*, Schmid S. Membrane fission by dynamin: what we know and what we need to know. EMBO J. 2016 Nov 2;35(21):2270-2284.
  3. Hohendahl A, Roux A, Galli V. Structural insights into the centronuclear myopathy-associated functions of BIN1 and dynamin 2. J Struct Biol. 2016 Jun 22. pii: S1047-8477(16)30121-6.
  4. Alessandri K, Feyeux M, Gurchenkov B, Delgado C, Trushko A, Krause KH, Vignjević D, Nassoy P, Roux A. A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC). Lab Chip. 2016 Apr 26;16(9):1593-604.
  5. Buckley, C., Gopaldass, N., Johnston, S.A., Soldati, T., Insall, R.H, and King, J.S. (2016) WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors. Proc Natl Acad Sci USA 113(40): E5906-E5915
  6. Zhang, X., and Soldati, T (2016) Of amoebae and men: Extracellular DNA traps as an ancient cell-intrinsic defence mechanism Frontiers in Immunology 7:269
  7. Van Voorhis, W.C., … Soldati, T., et al (2016) Open-source drug discovery with the Malaria Box compound collection for neglected diseases and beyond. PLoS Pathogens 12(7):e1005763
  8. Delincé, M., Bureau, J.-B., López Jiménez, A.T., Cosson, P., Soldati, T., and McKinney J. (2016) A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions. Lab on a Chip 16(17):3276-85
  9. Guého, A., Bosmani, C., Molle, V., Gopaldass, N., Soldati, T., and Letourneur, F. (2016) Dictyostelium EHD associates with Dynamin and participate in phagosome maturation. J. Cell Sci 129(12):2354-6
  10. Zhang, X., Zhuchenko, O., Kuspa, A., and Soldati, T. (2016) Social amoebae trap and kill bacteria by casting DNA nets. Nat. Commun. 7:10938
  11. Slepikas, L., Chiriano, G., Perozzo, R., Tardy, S., Kranjc-Pietrucci, A., Patthey-Vuadens, O., Ouertatani-Sakouhi, H., Kicka, S., Harrison, C., Scrignari, T., Perron, K., Hilbi, H., Soldati, T., Cosson, P., Tarasevicius, E., Scapozza, L. (2016) In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA J. Med. Chem Jan 5
  12. Kicka, S., Arafah, S., and Soldati, T. (2015) Dictyostelium as a model to study the biology of mycobacteria. Chapter in: “Free-living amoebae: an evolutionary crib for emerging pathogens” in press
  13. Holtzer, L., Oleinich, I., Anzola, M., Lindberg, E, Sadhu, K., González-Gaitán, M., Winssinger, N. (2016) Nucleic acid templated chemical reaction in a live vertebrate. ACS Central Science 2 (6), 394-400.
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  15. Viktoria Wollrab, Raghavan Thiagarajan, Anne Wald, Karsten Kruse and Daniel Riveline (2016) Still and rotating myosin clusters determine cytokinetic ring constriction. Nat commun 7, 11860
  16. D. Johann, D. Goswami and K.Kruse (2016) Assembly of bipolar microtube structures by passive cross-linkers and molecular motors. Phys. Rev. E 93, 062415
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  1. Chiaruttini N, Redondo-Morata L, Colom A, Humbert F, Lenz M, Scheuring S, Roux A. Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation. Cell. 2015 Nov 5;163(4):866-79. Highlighted in Dev Cell.
  2. Gonzalez-Gaitan M, Roux A. When cell biology meets theory. J Cell Biol. 2015 Sep 28;210(7):1041-5. Opinion article.
  3. Saleem M, Morlot S, Hohendahl A, Manzi J, Lenz M, Roux A. A balance between membrane elasticity and polymerization energy sets the shape of spherical clathrin coats. Nat Commun. 2015 Feb 19;6:6249. Highlighted in La Recherche.
  4. Dal Molin M, Verolet Q, Colom A, Letrun R, Derivery E, Gonzalez-Gaitan M, Vauthey E, Roux A, Sakai N, Matile S. Fluorescent flippers for mechanosensitive membrane probes. J Am Chem Soc. 2015 Jan 21;137(2):568-71.
  5. Dan Dunn J., Alvarez L.A., Zhang X., Soldati T. (2015) Reactive oxygen species and mitochondria: A nexus of cellular homeostasis. Redox Biol. 6:472-85
  6. Xie X., Gutiérrez A., Trofimov V., Szilagyi I., Soldati T., Bakker E. (2015) Charged Solvatochromic Dyes as Signal Transducers in pH Independent Fluorescent and Colorimetric Ion Selective Nanosensors. Anal Chem. 87(19):9954-9
  7. Harrison, C.F., Chiriano, G., Hoffmann, C., Petermann, O., Kranjc-Pietrucci, A., Patthey Vuadens, O., Kicka, S., Trovimov, V., Ouertatani-Sakouhi, H., Cosson, P., Soldati, T., Scapozza, L., and Hilbi, H. (2015) Amoebae-based screening reveals a novel family of compounds restricting intracellular Legionella. ACS Infectious Diseases 1 (7), pp 327–338
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  9. Barisch, C., López-Jiménez, A.T., and Soldati, T. (2015) Live Imaging of Mycobacterium marinum Infection in Dictyostelium discoideum. Methods Mol Biol 1285:369-85.
  10. Xie, X., Gutiérrez, A., Trofimov, T., Szilagyi, I., Soldati, T., and Bakker E. (2015) Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive Dyes, Chimia 69, No. 4 1-3
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  20. Gehin, C., J. Montenegro, E.K. Bang, A. Cajaraville, S. Takayama, H. Hirose, S. Futaki, S. Matile and H. Riezman (2013) Dynamic amphiphile libraries to screen for the “fragrant” delivery of siRNA into HeLa cells and human primary fibroblasts. J. Am. Chem. Soc., 135, 9295-9298.
  21. Lindberg, L. A.X. Santos, H. Riezman, L. Olsson and M. Bettiga (2013) Lipidomic profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii reveals critical changes in lipid composition in response to acetic acid stress. PLoS One 8, e 73936, doi 10.1371/journal.pone.0073936
  22. Ding, J. U. Loizides-Mangold, G. Rando, V. Zoete, C. Moret, O. Michielin, J. K. Reddy, W. Wahli, H. Riezman* and B. Thorens* (2013) The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium chain fatty acids. Cell Reports, 5, 248-258. doi: 10.1016/j.celrep.2013.08.03 * co-senior authors.
  23. Kajiwara, K. A. Ikeda, A. Aguilera-Romero, G.A. Castillon, S. Kagiwada, K. Hanada, H. Riezman, M. Muñiz, K. Funato (2013) Osh proteins regulate COPII- mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast. J. Cell Sci. in press. doi: 10.1242/jcs.132001
  24. Zimmermann, C., A.X.S. Santos, K. Gable, S. Epstein, C. Gururaj, P. Chymkowitch, D. Pultz, S. V. Rødkær, L. Clay, M. Bjørås, Y. Barral, A. Chang, N. J. Færgeman, T. M. Dunn, H. Riezman, and J. M. Enserink (2013) GSK3- mediated Elo2 phosphorylation regulates very long chain fatty acid synthesis and autophagy. Cell Reports, 5, 1036-1046. doi: 10.1016/j.celrep.2013.10.024
  25. Aguilera-Romero, A., C. Gehin and H. Riezman (2013) Sphingolipid homeostasis in the web of metabolic routes. Biochim, Biophys. Acta. Pii: doi: 10.1016/j.bbalip.2013.10.014
  26. Cohen, Y., M. Megyeri, O.C.Chen, G. Condomitti, I. Riezman, U. Loizides-Mangold, A. Abdul-Sada, N. Rimon, H. Riezman, F.M. Platt, A.H. Futerman, and M. Schuldiner (2013) The yeast P5 type ATPase, Spf1, regulates manganese transport into the endoplasmic reticulum. PLoS One, Dec 31, 8(12) e85519, doi: 10.1371/journal.pone.0085519


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  2. Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Böhm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J. Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome. Eur J Hum Genet. 2012 Oct 24.
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  5. Berchtold D, Piccolis M, Chiaruttini N, Riezman I, Riezman H, Roux A, Walther TC, Loewith R. (2012) Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. Nat Cell Biol, 14:542-547.
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  7. Soldati. T., and Neyrolles, O. (2012) Mycobacteria and the Intraphagosomal Environment: Take It With a Pinch of Salt(s)! Traffic 13(8):1042-52.
  8. Dieckmann, R., Monroy, R., Bloomfield, G., Ruppert, T., and Soldati, T. (2012) A balance in the delivery of ER components and the vacuolar proton pump to the phagosome depends on Myosin IK in Dictyostelium. Mol. Cell Proteomics 11(10):886-900.
  9. Friedrich, N., Hagedorn, M., Soldati, T., and Soldati-Favre, D. (2012) Prison break: Pathogen strategies for host cell egress. Microbiology and Molecular Biology Reviews 76(4):707-20.
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  12. Lima, W.C., Leuba, F., Soldati , T., and Cosson, P. (2012) Mucolipin controls lysosome exocytosis in Dictyostelium. J Cell Sci. 125(Pt 9):2315-22.
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  14. Jaiswal, P., Soldati, T., Thewes, S., and Baskar, R. (2012) Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds BMC Dev Biol. 12(1):5.
  15. Gopaldass, N., Patel, D., Kratzke, R., Dieckmann, R., Hausherr, S., Hagedorn, M., Neuhaus, E.M., Hoffman, E., Hille, K., Kuznetsov, S., and Soldati, T. (2012) Dynamin A, Myosin IB and Abp1 couple phagosome maturation to F-actin binding. Traffic 13(1):120-30.
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  21. Kicheva, A., Bollenbach, T., Wartlick, O., Jülicher, F., and González-Gaitán, M. (2012) Investigating the principles of morphogen gradient formation: from tissues to cells. Curr Opin Genet Dev 22:1-6
  22. Kobayashi, T., Komatsu, T., Kamiya, M., Campos, C., González-Gaitán, M., Terai, T., Hanaoka, K., Nagano, T., Urano, Y. (2012) Highly Activatable and Environment-insensitive Optical Highlighters for Selective Spatiotemporal Imaging of Target Proteins. Journal of the American Chemical Society, 134, 11153-11160
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  30. Loizides-Mangold, U, F.P. David, V.J. Nesatyy, T. Kinoshita and H. Riezman (2012) GPI anchors regulate glycosphingolipid levels. J. Lipid. Res. 53, 1522—34. doi: 10.1194/jlr.M025692
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  25. González-Gaitán, M., J. Gruenberg, T. Halazonetis, U.K. Laemmli, J.M. Matter, H. Riezman, O. Schaad, T. Soldati, and R. Watanabe (2009) The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis of Intracellular Organization. Chimia 63, 830-834.


  1. Frost, A., Perera, R., Roux, A., Spasov, K., Destaing, O., Egelman, E.H., De Camilli, P., and Unger, V.M. (2008). Structural basis of membrane invagination by F-BAR domains. Cell 132, 807-817. highlighted in Cell Preview.
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  20. Pichler, H. and H. Riezman (2004) Where sterols are required for endocytosis. Biochem. Biophys. Acta 1666, 51-61.
  21. Rodal. A.A., O. Sokolova, D.B. Robins, K.M. Daugherty, S. Hippenmeyer, H. Riezman, N. Grigorieff and B.L. Goode (2004) Conformational changes in the Arp2/3 complex leading to actin nucleation. Nature Struct. Mol. Biol. 12, 26 – 31.


  1. Abaza, A., Soleilhac, J.M., Westendorf, J., Piel, M., Crevel, I., Roux, A., and Pirollet, F. (2003). M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis. J Biol Chem 278, 27844-27852.
  2. Nizak, C., Martin-Lluesma, S., Moutel, S., Roux, A., Kreis, T.E., Goud, B., and Perez, F. (2003). Recombinant antibodies against subcellular fractions used to track endogenous Golgi protein dynamics in vivo. Traffic 4, 739-753.
  3. Soldati, T. (2003) Unconventional myosins, actin dynamics and endocytosis: A ménage à trois? Traffic, 4, 358-366.
  4. Gruenberg, J. (2003). "Lipids in endocytic membrane transport and sorting." Curr Opin Cell Biol 15(4): 382-8.
  5. Mayran, N., R. G. Parton and J. Gruenberg (2003). "Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells." Embo J 22(13): 3242-53.
  6. Petiot, A., J. Faure, H. Stenmark and J. Gruenberg (2003). "PI3P signaling regulates receptor sorting but not transport in the endosomal pathway." J Cell Biol 162(6): 971-9.
  7. Vieira, O. V., C. Bucci, R. E. Harrison, W. S. Trimble, L. Lanzetti, J. Gruenberg, A. D. Schreiber, P. D. Stahl and S. Grinstein (2003). "Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase." Mol Cell Biol 23(7): 2501-14.
  8. Wucherpfennig, T., Wilsch-Brauninger, M., and González-Gaitán, M. (2003). Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol 161, 609-624
  9. González-Gaitán, M., and Stenmark, H. (2003). Endocytosis and signaling: a relationship under development. Cell 115, 513-521
  10. González-Gaitán, M. (2003). Signal dispersal and transduction through the endocytic pathway. Nat Rev Mol Cell Biol 4, 213-224
  11. González-Gaitán, M. (2003). From disease to development to cell biology and back. Development 130, 5053-5057
  12. González-Gaitán, M. (2003). Endocytic trafficking during Drosophila development. Mech Dev 120, 1265-1282
  13. Kaksonen M, Sun Y, Drubin DG. (2003) A pathway for association of receptors, adaptors and actin during endocytic internalization. Cell 115: 475-487.
  14. Sekiya-Kawasaki M, Groen AC, Cope MJ, Kaksonen M, Watson HA, Zhang C, Shokat KM, Wendland B, McDonald KL, McCaffery JM, Drubin DG. (2003) Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis. J. Cell Biol. 162: 765-772.
  15. Pomorski T, R. Lombardi, H. Riezman, P.F. Devaux, G. Van Meer and J.C. Holthuis (2003) Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis. Mol. Biol. Cell. 14, 1240-54.
  16. Schaerer-Brodbeck, C. and H. Riezman (2003) Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast. FEMS Yeast Res., 4, 37-49.
  17. Morsomme, P. C. Prescianotto-Baschong and H. Riezman (2003) The ER v-SNAREs are required for GPI-anchored protein sorting from other secretory proteins upon exit from the ER. J. Cell Biol., 162, 403-412.
  18. Friant, S., K.D. Meier and H. Riezman (2003) Increased ubiquitin- dependent degradation can replace the essential requirement for heat shock protein induction. EMBO J., 22, 3783-3791.


  1. Roux, A., Cappello, G., Cartaud, J., Prost, J., Goud, B., and Bassereau, P. (2002). A minimal system allowing tubulation with molecular motors pulling on giant liposomes. Proc Natl Acad Sci USA 99, 5394-5399.
  2. Gotthardt, D., Warnatz, H.J., Henschel, O., Brückert, F., Schleicher, M., and Soldati, T. (2002) High resolution dissection of phagosome maturation reveals distinct membrane trafficking phases. Mol. Biol. Cell 13, 3508-3520.
  3. Herm-Götz, A., Weiss, S., Stratmann, R., Fujita-Becker, S., Ruff, C., Meyhöfer, E., Soldati, T, Manstein, D.J., Geeves, M.A., and Soldati, D. (2002) Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end directed motor. EMBO J. 21, 2149-2158.
  4. Neuhaus, E.M., Almers, W., and Soldati, T. (2002) Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum. Mol. Biol. Cell 13, 1390-1407.
  5. Kobayashi, T., M. H. Beuchat, J. Chevallier, A. Makino, N. Mayran, J. M. Escola, C. Lebrand, P. Cosson, T. Kobayashi and J. Gruenberg (2002). "Separation and characterization of late endosomal membrane domains." J Biol Chem 277(35): 32157-64.
  6. Lebrand, C., M. Corti, H. Goodson, P. Cosson, V. Cavalli, N. Mayran, J. Faure and J. Gruenberg (2002). "Late endosome motility depends on lipids via the small GTPase Rab7." Embo J 21(6): 1289-300.
  7. Sorice, M., D. Ferro, R. Misasi, V. Pittoni, A. Longo, A. Circella, T. Garofalo, R. Gradini, F. Violi, J. Gruenberg and G. Valesini (2002). "Evidence for anticoagulant activity and beta2-GPI accumulation in late endosomes of endothelial cells induced by anti-LBPA antibodies." Thromb Haemost 87(4): 735-41.
  8. van der Goot, F. G. and J. Gruenberg (2002). "Oiling the wheels of the endocytic pathway." Trends Cell Biol 12(7): 296-9.
  9. Felberbaum-Corti, M., F. G. Van Der Goot and J. Gruenberg (2003). "Sliding doors: clathrin-coated pits or caveolae?" Nat Cell Biol 5(5): 382-4.
  10. Guichet, A., Wucherpfennig, T., Dudu, V., Etter, S., Wilsch-Brauniger, M., Hellwig, A., González-Gaitán, M., Huttner, W.B., and Schmidt, A.A. (2002). Essential role of endophilin A in synaptic vesicle budding at the Drosophila neuromuscular junction. EMBO J 21, 1661-1672
  11. Entchev, E.V., and González-Gaitán, M.A. (2002). Morphogen gradient formation and vesicular trafficking. Traffic 3, 98-109
  12. Berdnik, D., Torok, T., González-Gaitán, M., and Knoblich, J.A. (2002). The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell 3, 221-231
  13. Kaksonen M, Pavlov I, Voikar V, Lauri SE, Hienola A, Riekki R , Lakso M, Taira T, Rauvala H. (2002) Syndecan-3 Deficient Mice Exhibit Enhanced LTP and Impaired Hippocampus-Dependent Learning. Mol. Cell. Neurosci. 21: 158-172.
  14. Pavlov I, Voikar V, Kaksonen M, Lauri SE, Hienola A, Taira T, Rauvala H. (2002) Role of Heparin-Binding Growth-Associated Molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice. Mol. Cell Neurosci. 20: 330-342.
  15. Prescianotto-Baschong, C. and H. Riezman (2002) Ordering of compartments in the yeast endocytic pathway. Traffic 3, 37-49.
  16. Morsomme, P. and H. Riezman (2002) The Rab GTPase Ypt1p and tethering factors couple protein sorting at the ER to vesicle targeting to the Golgi apparatus. Dev. Cell 2, 307-317.
  17. Roh, D.-H., B. Bowers, H. Riezman, and E. Cabib (2002) Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wall. Mol. Microbiol., 44, 1167-1184.
  18. Riezman, H. (2002) The ubiquitin connection. Nature 416, 381-382.
  19. Henry, K.R., K. D'Hondt, J. Chang, T. Newpher, K. Huang, R.T. Hudson, H. Riezman, and S.K. Lemmon (2002) Scd5p and clathrin function are important for cortical actin organization, endocytosis and localization of Sla2p in yeast. Mol. Biol. Cell, 13, 2607-2625.
  20. Heese-Peck, A., H. Pichler, B. Zanolari, R. Watanabe, G. Daum, and H. Riezman (2002) Multiple functions of sterols in yeast endocytosis. Mol. Biol. Cell, 13, 2664-2680.
  21. Venkataraman, K., C. Riebeling, J. Bodennec, H. Riezman, J.C. Allegood, M.C. Sullards, A.H. Merrill and A.H. Futerman (2002) Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18- (dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J. Biol. Chem. 377, 35642-35649.
  22. Funato, K., B. Vallée and H. Riezman (2002) Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae. Biochemistry, 41, 15105-15114.
  23. Watanabe, R., K. Funato, K. Venkataraman, A.H. Futerman and H. Riezman (2002) Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast. J. Biol. Chem., 277, 49538-49544. (IF = 6.4)
  24. Funato, K., R. Lombardi, B. Vallée and H. Riezman (2002) Lcb4p is a Key Regulator of Ceramide Synthesis from Exogenous Long Chain Sphingoid Base in Saccharomyces cerevisiae. J. Biol. Chem., 278, 7325-7534.


  1. Matter-Sadzinski, L., Matter, J.-M., Ong, M.T., Hernandez, J. and Ballivet, M. (2001). Specification of neurotransmitter receptor identity in developing retina: the chick ATH5 promoter integrates the positive and negative effects of several bHLH proteins. Development, 128, 217-231.
  2. Delbac, F., Sänger A., Neuhaus, E.M., Stratmann, R., Ajioka, J.W., Toursel, C., Herm-Götz, A., Tomavo S., Soldati, T., and Soldati, D. (2001) Toxoplasma gondii myosins B/C: One gene, two tails, two localizations and a role in parasite division. J. Cell Biol., 155, 613-623.
  3. Gillespie, P.G., Soldati, T., et al. (2001) Myosin-I nomenclature. J. Cell Biol. 155, 704-704.
  4. Cavalli, V., F. Vilbois, M. Corti, M. J. Marcote, K. Tamura, M. Karin, S. Arkinstall and J. Gruenberg (2001). "The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex." Mol Cell 7(2): 421-32.
  5. Cavalli, V., M. Corti and J. Gruenberg (2001). "Endocytosis and signaling cascades: a close encounter." FEBS Lett 498(2-3): 190-6.
  6. Dunoyer-Geindre, S., E. K. Kruithof, B. Galve-de Rochemonteix, C. Rosnoblet, J. Gruenberg, G. Reber and P. de Moerloose (2001). "Localization of beta2-glycoprotein 1 in late endosomes of human endothelial cells." Thromb Haemost 85(5): 903-7.
  7. Fratti, R. A., J. M. Backer, J. Gruenberg, S. Corvera and V. Deretic (2001). "Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest." J Cell Biol 154(3): 631-44.
  8. Gruenberg, J. (2001). "The endocytic pathway: a mosaic of domains." Nat Rev Mol Cell Biol 2(10): 721-30.
  9. Felberbaum-Corti, M. and J. Gruenberg (2002). "Signaling from the far side." Mol Cell 10(6): 1259-60.
  10. Reizes O, Lincecum J, Wang Z, Goldberger O, Huang L, Kaksonen M, Ahima R, Hinkes MT, Barsh GS, Rauvala H, Bernfield M. (2001) Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3. Cell 106: 105-116.
  11. Muñiz, M., P. Morsomme, and H. Riezman (2001) Protein sorting upon exit from the endoplasmic reticulum. Cell, 104, 313-320. (IF = 28.4)
  12. Lombardi, R. and H. Riezman (2001) Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivo. J. Biol. Chem., 276, 6016- 6022. (IF = 6.4)
  13. Lombardi, R., S. Friant, and H. Riezman (2001) Endocytosis in Saccharomyces cerevisiae: involvement of actin, actin-associated protein complexes, lipids in the internalization step, in Frontiers in Molecular Biology, Oxford University Press, Ed. M. Marsh.
  14. Wiederkehr, A., K.D. Meier, and H. Riezman (2001) Identification and characterization of eleven S. cerevisiae mutants defective in fluid-phase endocytosis. Yeast, 18, 759-773. (IF, not available)
  15. Galan, J.M., A. Wiederkehr, J.H. Seol, R. Haguenauer-Tsapis, R.J. Deshaies, H. Riezman, and M. Peter (2001) Skp1p and the F-box protein Rcy1p form a non- SCF complex involved in recycling of the SNARE Snc1p in yeast. Mol. Cell. Biol., 21, 3105-3117.
  16. Zahn, R., B.J. Stevenson, S. Schröder-Köhne, B. Zanolari, H. Riezman, and A.L. Munn (2001) End13p/Vps4p Is required for efficient transport from early to late endosomes in Saccharomyces cerevisiae. J. Cell Sci., 114, 1935-1947.
  17. Schörling, S., B. Vallée, W.P. Barz, H. Riezman, and D. Oesterhelt (2001) Lag1p and Lac1p are essential for the acyl-CoA-dependent ceramides synthase reaction in Saccharomyces cerevisiae. Mol. Biol. Cell, 12, 3417-3427.
  18. Friant, S., R. Lombardi, T. Schmelzle, M.N. Hall, and H. Riezman (2001) Sphingosine signalling via PKH kinases is required for endocytosis in yeast. EMBO J., 20, 6783-6792.
  19. Funato, K. and H. Riezman (2001) Vesicular and non-vesicular transport of ceramide from ER to the Golgi apparatus in yeast. J. Cell. Biol., 155, 949-959.


  1. Matter, J.-M. and Ballivet, M. (2000). Gene structure and transcriptional regulation of the neuronal nicotinic acetylcholine receptors. In Handbook of Experimental Pharmacology, vol. 144, (Clementi, Fornasari, Gotti, eds) pp 33-55 (Springer-Verlag).
  2. Erkman, L., Matter, J.-M., Matter-Sadzinski, L. and Ballivet, M. (2000). Nicotinic acetylcholine receptor gene expression in developing chick autonomic ganglia. Eur. J. Pharmacol. 393, 97-104.
  3. Monnat, J., Neuhaus, E.M., Pop, M.S., Ferrari, D., Kramer, B., and Soldati, T. (2000) Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase. Mol. Biol. Cell 11, 3469-3484.
  4. Neuhaus, E.M., and Soldati, T. (2000) A myosin I is involved in membrane recycling from early endosomes. J. Cell Biol. 150, 1013-1026.
  5. Lang, T., Wacker, I., Wunderlich, I., Rohrbach, A., Giese, G., Soldati, T., and Almers, W. (2000) Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells. Biophys. J., 78, 2863-2877.
  6. Hettmann, C., Herm, A., Geiter, A., Frank, B., Schwarz, E., Soldati, T., and Soldati, D. (2000) A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization. Mol. Biol. Cell 11, 1385-1400.
  7. Geissler, H., Ullmann, R., and Soldati, T. (2000) The tail domain of myosin M catalyses nucleotide exchange on Rac1-GTPases and can induce actin-driven surface protrusions. Traffic 1, 399-410.
  8. Schwarz, E.C., Neuhaus, E.M., Kistler, C., Henkel, A.W., and Soldati, T. (2000) Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosis. J. Cell Sci., 113, 621-633.
  9. Bao, J., I. Alroy, H. Waterman, E. D. Schejter, C. Brodie, J. Gruenberg and Y. Yarden (2000). "Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome." J Biol Chem 275(34): 26178-86.
  10. Chevallier, J., N. Sakai, F. Robert, T. Kobayashi, J. Gruenberg and S. Matile (2000). "Rapid access to synthetic lysobisphosphatidic acids using P(III) chemistry." Org Lett 2(13): 1859-61.
  11. Gagescu, R., J. Gruenberg and E. Smythe (2000). "Membrane dynamics in endocytosis: structure—function relationship." Traffic 1(1): 84-8.
  12. Gagescu, R., N. Demaurex, R. G. Parton, W. Hunziker, L. A. Huber and J. Gruenberg (2000). "The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components." Mol Biol Cell 11(8): 2775-91.
  13. Galve-de Rochemonteix, B., T. Kobayashi, C. Rosnoblet, M. Lindsay, R. G. Parton, G. Reber, E. de Maistre, D. Wahl, E. K. Kruithof, J. Gruenberg and P. de Moerloose (2000). "Interaction of anti-phospholipid antibodies with late endosomes of human endothelial cells." Arterioscler Thromb Vasc Biol 20(2): 563-74.
  14. Huber, L. A., I. Fialka, K. Paiha, W. Hunziker, D. B. Sacks, M. Bahler, M. Way, R. Gagescu and J. Gruenberg (2000). "Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cells." Traffic 1(6): 494-503.
  15. Juuti-Uusitalo, K., K. J. Airenne, A. Laukkanen, E. L. Punnonen, V. M. Olkkonen, J. Gruenberg, M. Kulomaa and V. Marjomaki (2000). "Selective targeting of avidin/mannose 6-phosphate receptor chimeras to early or late endosomes." Eur J Cell Biol 79(7): 458-68.
  16. Kobayashi, T., U. M. Vischer, C. Rosnoblet, C. Lebrand, M. Lindsay, R. G. Parton, E. K. Kruithof and J. Gruenberg (2000). "The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells." Mol Biol Cell 11(5): 1829-43.
  17. Simons, K. and J. Gruenberg (2000). "Jamming the endosomal system: lipid rafts and lysosomal storage diseases." Trends Cell Biol 10(11): 459-62.
  18. Alpy, F., M. E. Stoeckel, A. Dierich, J. M. Escola, C. Wendling, M. P. Chenard, M. T. Vanier, J. Gruenberg, C. Tomasetto and M. C. Rio (2001). "The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein." J Biol Chem 276(6): 4261-9.
  19. González-Gaitán, M., and Jackle, H. (2000). Tip cell-derived RTK signaling initiates cell movements in the Drosophila stomatogastric nervous system anlage. EMBO Rep 1, 366-371
  20. Entchev, E.V., Schwabedissen, A., and González-Gaitán, M. (2000). Gradient formation of the TGF-beta homolog Dpp. Cell 103, 981-991
  21. Kaksonen M, Peng HB and Rauvala H. (2000) Association of cortactin with dynamic actin in lamellipodia and on endosomal vesicles. J. Cell Sci. 113: 4421-4426.
  22. Kilpelainen I, Kaksonen M, Avikainen H, Fath M, Linhardt RJ, Raulo E and Rauvala H. (2000) Heparin-binding growth-associated molecule contains two heparin-binding beta-sheet domains that are homologous to the thrombospondin type I repeat. J. Biol. Chem. 275: 13564-13570.
  23. Rauvala H, Huttunen HJ, Fages C, Kaksonen M, Kinnunen T, Imai S, Raulo E, Kilpelainen I. (2000) Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility. Matrix Biol. 19: 377-387.
  24. Lewis, M.J., B. J. Nichols, C. Prescianotto-Baschong, H. Riezman and H.R.B. Pelham (2000) Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol. Biol. Cell, 11, 23-38.
  25. Muñiz, M. and H. Riezman (2000) Intracellular transport of GPI-anchored proteins. EMBO J., 19, 10-15.
  26. Schärer-Brodbeck, C. and H. Riezman (2000) Saccharomyces cerevisiae Arc35p works through two genetically separable calmodulin functions to regulate the actin and tubulin cytoskeletons. J. Cell Sci., 113, 521-532.
  27. Schärer-Brodbeck, C. and H. Riezman (2000) Functional interactions between the p35 subunit of the Arp2/3 complex and calmodulin in yeast. Mol. Biol. Cell, 11, 1113-1127.
  28. Muñiz, M., C. Nuoffer, H.P. Hauri and H. Riezman (2000) The Emp24p complex recruits a specific cargo molecule into ER-derived vesicles. J. Cell Biol., 148, 925-930.
  29. Ohishi, K., N. Inoue, Y. Maeda, J. Takeda, H. Riezman, and T. Kinoshita (2000) Gaa1p and Gpi8p are components of a GPI transamidase that mediates attachment of glycosylphosphatidylinositol to proteins. Mol. Biol. Cell, 11, 1523- 1533.
  30. Wiederkehr, A., S. Avaro, C. Prescianotto-Baschong, R. Haguenauer-Tsapis and H. Riezman (2000) The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in S. cerevisiae. J. Cell Biol., 149, 397-410.
  31. Zanolari, B., S. Friant, K. Funato, C. Sütterlin, B. J. Stevenson and H. Riezman (2000) Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. EMBO J., 19, 2824-2833.
  32. Friant, S., B. Zanolari and H. Riezman (2000) Increased protein kinase or decreased PP2A activity bypass sphingoid base requirement in endocytosis. EMBO J., 19, 2834-2844.
  33. Nagamune, K., T. Nozaki, Y. Maeda, K. Ohishi, T. Fukuma, T. Hara, R.T. Schwarz, C. Sütterlin, R. Brun, H. Riezman and T. Kinoshita (2000) Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei. Proc. Nat. Acad. Sci. USA, 97, 10336-10341.
  34. D’Hondt, K., A. Heese-Peck and H. Riezman (2000) requirements for endocytosis Ann. Rev. Genet., 34, 255-295. Protein and lipid
  35. Geli, M.I., R. Lombardi, B. Schmelzl and H. Riezman (2000) An Intact SH3 Domain Is Required for Myosin I-Induced Actin Polymerization. EMBO J., 19, 4281-4291.
  36. Gagny B., A. Wiederkehr, P. Dumoulin, B. Winsor, H. Riezman, and R. Haguenauer-Tsapis (2000) A novel EH domain protein of Saccharomyces cerevisiae, Ede1p, involved in endocytosis. J. Cell Sci. 113, 3309-3319.
  37. Schärer-Brodbeck, C. and H. Riezman (2000) Interdependence of filamentous actin and microtubules for asymmetric cell division. Biol. Chem., 381, 815-825.

Before 2000

  1. Schwarz, E.C., Geissler, H., and Soldati, T. (1999) A potentially exhaustive screening strategy reveals two novel divergent myosins in Dictyostelium. Cell Biochem. Biophys. 30, 413-435.
  2. Ulbricht, B., and Soldati, T. (1999) Production of reagents and optimization of methods for studying calmodulin-binding proteins. Prot. Expr. Purif. 15, 24-33.
  3. Neuhaus, E.M., and Soldati, T. (1999) Molecular mechanisms of membrane trafficking - What do we learn from Dictyostelium discoideum ? Protist 150, 235-243.
  4. Soldati, T., Schwarz, E., and Geissler, H. (1999) Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling. Protoplasma 209, 28-37.
  5. Soldati, T., Geissler, H., and Schwarz, E. (1999) How many is enough ? Exploring the myosin repertoire in the model eukaryote Dictyostelium discoideum. Cell Biochem. Biophys. 30, 389-411.
  6. Neuhaus, E., Horstmann, H., Almers, W., Maniak, M., and Soldati, T. (1998) Ethane-freezing/methanol-fixation of cell monolayers. A procedure for improved preservation of structure and antigenicity for light and electron microscopies. J. Struct. Biol. 121, 326-342.
  7. Monnat, J., Hacker, U., Geissler, H., Rauchenberger, R., Neuhaus, E., Maniak, M., and Soldati, T. (1997) Dictyostelium discoideum Protein Disulfide Isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signal. FEBS Lett., 418, 357-362.
  8. Lang, T., Wacker, I., Steyer, J., Kaether, C., Wunderlich, I., Soldati, T., Gerdes, H. and Almers, W. (1997) Ca2+ -triggered peptide secretion in single cells imaged with green fluorescent protein and evanescent-wave microscopy. Neuron 18, 857-863.
  9. Komiyama, M., Soldati, T., von Arx, P. and Perriard, J.-C. (1996) The sorting specificity of myosin alkali light chain isoproteins reflects the sequence of developmental expression as determined by double epitope-tagging competition. J. Cell Sci. 109, 2089-2099.
  10. Von Arx, P., Bantle, S., Soldati. T. and Perriard, J.-C. (1995) Dominant Negative Effect of Cytoplasmic Actin Isoproteins on Cardiomyocyte Cytoarchitecture and Function. J. Cell Biol. 131(6), 1759-1773.
  11. Riederer, M.A., Soldati, T., Dirac-Svejstrup, A.B., and Pfeffer, S.R. (1995) Expression of Rab9 protein in Escherichia coli, Purification and isoprenylation in vitro. Meth. Enzym. 257, 15-21.
  12. Soldati, T., Rancaño, C., Geissler, H. and Pfeffer, S.R. (1995) Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes. J. Biol. Chem. 270(43), 25541-25548.
  13. Soldati, T., Shapiro, A.D. and Pfeffer, S.R. (1995) Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP Dissociation Inhibitor complexes and endosome-enriched membranes. Meth. Enzym. 257, 253-259.
  14. Pfeffer, S.R., Dirac-Svejstrup, A.B. and Soldati, T. (1995) Rab GDP Dissociation Inhibitor: putting Rab GTPases in the right place. J. Biol. Chem. 270(29), 17057-17059.
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