172. “An expedient approach to the total synthesis of (+)-5-epi-eudesma-4(15)-ene-1β,6β-diol”
     G. Parthasarathy, C. Besnard, E.P. Kündig,
     Chem. Commun. 2012, 48, 11241-11243.

The first total synthesis of (+)-5-epi-eudesma-4(15)-ene-1β,6β-diol has been achieved in 12 steps by starting from the known (-)-cis-piperitol and using an Ireland-Claisen rearrangement of a glycolate ester and an intramolecular nitrile oxide dipolar cycloaddition as key steps.

DOI : 10.1039/C2CC36260K 

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