1. Flipper Probes for the Community
    Assies, L.; García-Calvo, J.; Piazzolla, F.; Sanchez, S.; Kato, T.; Reymond, L.; Goujon, A.; Colom, A.; López-Andarias, J.; Straková, K.; Mahecic, D.; Mercier, V.; Riggi, M.; Jiménez-Rojo, N.; Roffay, C.; Licari, G.; Tsemperouli, M.; Neuhaus, F.; Fürstenberg, A.; Vauthey, E.; Hoogendoorn, S.; Gonzalez-Gaitan, M.; Zumbuehl, A.; Sugihara, K.; Gruenberg, J.; Riezman, H.; Loewith, R.; Manley, S.; Roux, A.; Winssinger, N.; Sakai, N.; Pitsch, S.; Matile, S.
    CHIMIA 2021, 75, 1004-1011
  1. Nickel-Catalyzed Kumada Vinylation of Enol Phosphates: A Comparative Mechanistic Study
    Poisson, P.-A.; Tran, G.; Besnard, C.; Mazet, C.
    ACS Catal. 2021, 11, 15041-15050
  1. Passive Coupling of Membrane Tension and Cell Volume During Active Response of Cells to Osmosis
    Roffay, C.; Molinard, G.; Kim, K.; Urbanska, M.; Andrade, V.; Barbarasa, V.; Nowak, P.; Mercier, V.; García-Calvo, J.; Matile, S.; Loewith, R.; Echard, A.; Guck, J.; Lenz, M.; Roux, A.
    Proc. Natl. Acad. Sci. USA 2021, 118, e2103228118
  1. Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries
    Sabale, P. M.; Imiołek, M.; Raia, P.; Barluenga, S.; Winssinger, N.
    J. Am. Chem. Soc. 2021, 143, 18932-18940
  1. Compensatory Ion Transport Buffers Daily Protein Rhythms to Regulate Osmotic Balance and Cellular Physiology
    Stangherlin, A.; Watson, J. L.; Wong, D. C. S.; Barbiero, S.; Zeng, A.; Seinkmane, E.; Chew, S. P.; Beale, A. D.; Hayter, E. A.; Guna, A.; Inglis, A. J.; Putker, M.; Bartolami, E.; Matile, S.; Lequeux, N.; Pons, T.; Day, J.; van Ooijen, G.; Voorhees, R. M.; Bechtold, D. A.; Derivery, E.; Edgar, R. S.; Newham, P.; O’Neill, J. S.
    Nat. Commun. 2021, 12, 1107
  1. Photocatalysis in Chemical Biology: Extending the Scope of Optochemical Control and Towards New Frontiers in Semisynthetic Bioconjugates and Biocatalysis
    Liu, W.; Watson, E. E.; Winssinger, N.
    Helv. Chim. Acta 2021, 104, e2100179
  1. Dithiolane Quartets: Thiol-Mediated Uptake Enables Cytosolic Delivery in Deep Tissue
    Martinent, R.; Tawffik, S.; López-Andarias, J.; Moreau, D.; Laurent, Q.; Matile, S.
    Chem. Sci. 2021, 12, 13922-13929
  1. Growth dynamics and electron reflectivity in ultrathin films of chiral heptahelicene on metal (100) surfaces studied by spin-polarized low energy electron microscopy
    Baljozović, M.; Fernandes Cauduro, A. L.; Seibel, J.; Mairena, A.; Grass, S.; Lacour, J.; Schmid, A. K.; Ernst, K.-H.
    Phys. Status Solidi B 2021, 258, 2170054
  1. Pnictogen-Bonding Catalysis and Transport Combined: Polyether Transporters Made In Situ
    Humeniuk, H. V.; Gini, A.; Hao, X.; Coelho, F.; Sakai, N.; Matile, S.
    JACS Au 2021, 1, 1588-1593
  1. Regioselective Short Synthesis of Epi-Isoborneol Neopentyl Ether as Chiral Auxiliary An Absolute Configuration Reset
    Piatek, A.; Chapuis, C.
    Helv. Chim. Acta 2021, 104, e2100142
  1. La formation des vésicules intraluminales de l’endosome est contrôlée par la tension membranaire
    [The Biogenesis of Intra-lumenal Vesicles is Regulated by Endosomal Membrane Tension]
    Mercier, V.; Larios, J.; Molinard, G.; Goujon, A.; Matile, S.; Roux, A.; Gruenberg, J.
    Med. Sci. 2021, 37, 697-700
  1. Computational Study of Benzosultam Formation through Gold(I)-Catalyzed Ammoniumation/Nucleophilic Substitution Reaction
    Pertschi, R.; de Aguirre, A.; Pale, P.; Blanc, A.; Poblador Bahamonde, A. I.
    Helv. Chim. Acta 2021, 104, e2100133
  1. Teflon Magnetic Stirring Capsules (TMSC) as a Practical and Reusable Delivery System for Sensitive Reagents and Catalysts
    Taillemaud, S.; Rosset, S.; Mazet, C.
    Helv. Chim. Acta 2021, 104, e2100110
  1. Spirocyclic Amide Acetal Synthesis by [CpRu]-Catalyzed Condensations of α-Diazo-β-Ketoesters with γ-Lactams
    Pertschi, R.; Brun, E.; De Aguirre Fondevila, A.; Guénée, L.; Poblador-Bahamonde, A. I.; Lacour, J.
    Helv. Chim. Acta 2021, 104, e2100122
  1. Access to Highly Stereodefined 1,4-cis-Polydienes by a [Ni/Mg] Orthogonal Tandem Catalytic Polymerization
    Fiorito, D.; Simon, M.; Thomas, C. M.; Mazet, C.
    J. Am. Chem. Soc. 2021, 143, 13401-13407
  1. Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis
    Liu, W.; Winssinger, N.
    Synthesis 2021, 53, 3977-3990
  1. SARS-COV2- infection as a trigger of humoral response against apolipoprotein A-1
    Pagano, S.; Yerly, S.; Meyer, B.; Juillard, C.; Suh, N.; Le Terrier, C.; Daguer, J.-P.; Farrera-Soler, L.; Barluenga, S.; Piumatti, G.; Hartley, O.; Lemaitre, B.; Eberhardt, C. S.; Siegrist, C.-A.; Eckerle, I.; Stringhini, S.; Guessous, I.; Kaiser, L.; Pugin, J.; Winssinger, N.; Vuilleumier, N.
    Atherosclerosis 2021, 331, e78
  1. SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1
    Pagano, S.; Yerly, S.; Meyer, B.; Juillard, C.; Suh, N.; Le Terrier, C.; Daguer, J.-P.; Farrera-Soler, L.; Barluenga, S.; Piumatti, G.; Hartley, O.; Lemaitre, B.; Eberhardt, C. S.; Siegrist, C.-A.; Eckerle, I.; Stringhini, S.; Guessous, I.; Kaiser, L.; Pugin, J.; Winssinger, N.; Vuilleumier, N.
    Eur. J. Clin. Invest. 2021, 51, e13661
  1. Diastereoselective Amplification of a Mechanically Chiral [2]Catenane
    Caprice, K.; Pál, D.; Besnard, C.; Galmés, B.; Frontera, A.; Cougnon, F. B. L.
    J. Am. Chem. Soc. 2021, 143, 11957-11962
  1. Inhibition of Thiol-Mediated Uptake with Irreversible Covalent Inhibitors
    Lim, B.; Cheng, Y.; Kato, T.; Pham, A.-T.; Le Du, E.; Mishra, A. K.; Grinhagena, E.; Moreau, D.; Sakai, N.; Waser, J.; Matile, S.
    Helv. Chim. Acta 2021, 104, e2100085
  1. Oligonucleotide Phosphorothioates Enter Cells by Thiol-Mediated Uptake
    Laurent, Q.; Martinent, R.; Moreau, D.; Winssinger, N.; Sakai, N.; Matile, S.
    Angew. Chem. Int. Ed. 2021, 60, 19102-19106
  1. Dual Bcl-XL /Bcl-2 inhibitors discovered from DNA-encoded libraries using a fragment pairing strategy
    Daguer, J.-P.; Gonse, A.; Shchukin, Y.; Farrera-Soler, L.; Barluenga, S.; Winssinger, N.
    Bioorg. Med. Chem. 2021, 44, 116282
  1. Kinetically Controlled Stereoselective Access to Branched 1,3-Dienes by Ru-Catalyzed Remote Conjugative Isomerization
    Scaringi, S.; Mazet, C.
    ACS Catal. 2021, 11, 7970-7977
  1. Bioinspired Ether Cyclizations within a π-Basic Capsule Compared to Autocatalysis on π-Acidic Surfaces and Pnictogen-Bonding Catalysts
    Hao, X.; Li, T.-R.; Chen, H.; Gini, A.; Zhang, X.; Rosset, S.; Mazet, C.; Tiefenbacher, K.; Matile, S.
    Chem. Eur. J. 2021, 27, 12215-12223
  1. Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides
    Liu, W.; Patouret, R.; Barluenga, S.; Plank, M.; Loewith, R.; Winssinger, N.
    ACS Cent. Sci. 2021, 7, 954-962
  1. Structural analysis of water in ionic liquid domains – A low pressure study
    Dziubinska-Kühn, K.; Croese, J.; Pupier, M.; Matysik, J.; Viger-Gravel, J.; Karg, B.; Kowalska, M.
    J. Mol. Liq. 2021, 334, 116447
  1. A minimal hybridization chain reaction (HCR) system using peptide nucleic acids
    Kim, K. T.; Angerani, S.; Winssinger, N.
    Chem. Sci. 2021, 12, 8218-8223
  1. Enabling Cyclization Strategies through Carbonyl-Ylide-Mediated Synthesis of Malonate Enol Ethers
    Viñas-Lóbez, J.; Levitre, G.; de Aguirre, A.; Besnard, C.; Poblador-Bahamonde, A. I.; Lacour, J.
    ACS Org. Inorg. Au 2021, 1, 11-17
  1. Thiol-Mediated Uptake
    Laurent, Q.; Martinent, R.; Lim, B.; Pham, A.-T.; Kato, T.; López-Andarias, J.; Sakai, N.; Matile, S.
    JACS Au 2021, 1, 710-728
  1. The Nuclear Transport Protein Importin-5: A Promising Target in Oncology and Virology
    Patouret, R.
    CHIMIA 2021, 75, 319-322
  1. Experimental Identification of Immunodominant B-cell Epitopes from SARS-CoV-2
    Farrera Soler, L.; Daguer, J.-P.; Barluenga, S.; Winssinger, N.
    CHIMIA 2021, 75, 276-284
  1. Combined spectroscopic studies on post-functionalized Au25 cluster as an ATR-FTIR sensor for cations
    Baghdasaryan, A.; Brun, E.; Wang, Y.; Salassa, G.; Lacour, J.; Bürgi, T.
    Chem. Sci. 2021, 12, 7419-7427
  1. Mitochondrial Membrane Tension Governs Fission
    Mahecic, D.; Carlini, L.; Kleele, T.; Colom, A.; Goujon, A.; Matile, S.; Roux, A.; Manley, S.
    Cell Rep. 2021, 35, 108947
  1. Rh(II)-Catalyzed Condensations of N-Sulfonyl-1,2,3-triazoles with Aminals
    Saleh, N.; Lacour, J.
    SynOpen 2021, 5, 134-137
  1. The Primary Dipole of Flipper Probes
    García-Calvo, J.; López-Andarias, J.; Sakai, N.; Matile, S.
    Chem. Commun. 2021, 57, 3913-3916
  1. Two-step immobilization of metronidazole prodrug on TEMPO cellulose nanofibrils through thiol-yne click chemistry for in situ controlled release
    Durand, H.; Baussanne, I.; Demeunynck, M.; Vigier-Gravel, J.; Emsley, L.; Bardet, M.; Zeno, E.; Belgacem, N.; Bras, J.
    Carbohydr. Polym. 2021, 262, 117952
  1. Hybrids of Cationic [4]Helicene and N-Heterocyclic Carbene as Ligands for Complexes Exhibiting (Chir)Optical Properties in the Far Red Spectral Window
    Tarrieu, R.; Hernandez Delgado, I.; Zinna, F.; Dorcet, V.; Colombel-Rouen, S.; Crévisy, C.; Baslé, O.; Bosson, J.; Lacour, J.
    Chem. Commun. 2021, 57, 3793-3796
  1. Bright Long-Lived Circularly Polarized Luminescence in Chiral Chromium(III) Complexes
    Jiménez, J.-R.; Poncet, M.; Míguez-Lago, S.; Grass, S.; Lacour, J.; Besnard, C.; Cuerva, J. M.; Campaña, A. G.; Piguet, C.
    Angew. Chem. Int. Ed. 2021, 60, 10095-10102
  1. Luciferase Controlled Protein Interactions
    Chang, D.; Feng, S.; Girik, V.; Riezman, H.; Winssinger, N.
    J. Am. Chem. Soc. 2021, 143, 3665-3670
  1. Kinesin-1 activity recorded in living cells with a precipitating dye
    Angerani, S.; Lindberg, E.; Klena, N.; Bleck, C. K. E.; Aumeier, C.; Winssinger, N.
    Nat. Commun. 2021, 12, 1463
  1. Organic Chemistry for First Year Medical Students: Addressing the Grand Public
    Matile, S.
    CHIMIA 2021, 75, 27-32
  1. Long-Lived Triplet Charge-Separated State in Naphthalenediimide Based Donor–Acceptor Systems
    Aster, A.; Rumble, C.; Bornhof, A.-B.; Huang, H.-H.; Sakai, N.; Solomek, T.; Matile, S.; Vauthey, E.
    Chem. Sci. 2021, 12, 4908-4915
  1. Biosupramolecular Systems: Integrating Cues into Responses
    Watson, E. E.; Angerani, S.; Sabale, P. M.; Winssinger, N.
    J. Am. Chem. Soc. 2021, 143, 4467-4482
  1. Fluorescent Membrane Tension Probes for Early Endosomes
    Piazzolla, F.; Mercier, V.; Assies, L.; Sakai, N.; Roux, A.; Matile, S.
    Angew. Chem. Int. Ed. 2021, 60, 12258-12263
  1. Singlet Fission in a Flexible Bichromophore with Structural and Dynamic Control
    Aster, A.; Zinna, F.; Rumble, C.; Lacour, J.; Vauthey, E.
    J. Am. Chem. Soc. 2021, 143, 2361-2371
  1. Total Syntheses of Paraconic Acids and 1,10-seco -Guaianolides via a Barbier Allylation/Translactonization Cascade of 3-(Bromomethyl)-2(5H )-furanone
    Liu, W.; Yu, Z.; Winssinger, N.
    Org. Lett. 2021, 23, 969-973
  1. Chiral Near-Infrared Fluorophores by Self-Promoted Oxidative Coupling of Cationic Helicenes with Amines/Enamines
    Bosson, J.; Labrador, G. M.; Besnard, C.; Jacquemin, D.; Lacour, J.
    Angew. Chem. Int. Ed. 2021, 60, 8733-8738
  1. Lifetime Broadening and Impulsive Generation of Vibrational Coherence Triggered by Ultrafast Electron Transfer
    Aster, A.; Bornhof, A.-B.; Sakai, N.; Matile, S.; Vauthey, E.
    J. Phys. Chem. Lett. 2021, 12, 1052-1057
  1. Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells:  Precisely Localized Controlled Release by External Chemical Stimulation
    López-Andarias, J.; Straková, K.; Martinent, R.; Jiménez-Rojo, N.; Riezman, H.; Sakai, N.; Matile, S.
    JACS Au 2021, 1, 221-232
  1. Anion Transport in Lipid Bilayer Membranes Using Halogen Bonds
    Vargas Jentzsch, A.; Matile, S.
    in Halogen Bonding in Solution; Huber, S. (Ed.) Wiley, 2021; Chapter 6; p. 195-231
  1. High Sensitivity Detection of a Solubility Limiting Surface Transformation of Drug Particles by DNP SENS
    Viger-Gravel, J.; Pinon, A. C.; Björgvinsdóttir, S.; Skantze, U.; Svensk Ankarberg, A.; Von corswant, C.; Schantz, S.; Emsley, L.
    J. Pharm. Sci. 2021, 110, 2452-2456
  1. Role of Intercluster and Interligand Dynamics of [Ag25(DMBT)18] Nanoclusters by Multinuclear Magnetic Resonance Spectroscopy
    Salassa, G.; Krishnadas, K. R.; Pupier, M.; Viger-Gravel, J.; Bürgi, T.
    J. Phys. Chem. C 2021, 125, 2524-2530
  1. Transition metal-catalyzed alkene isomerization as an enabling technology in tandem, sequential and domino processes
    Fiorito, D.; Scaringi, S.; Mazet, C.
    Chem. Soc. Rev. 2021, 50, 1391-1406
  1. Regiodivergent synthesis of pyrazino-indolines vs. triazocines via α-imino carbenes addition to imidazolidines
    Guarnieri-Ibáñez, A.; de Aguirre Fondevila, A.; Besnard, C.; Poblador Bahamonde, A. I.; Lacour, J.
    Chem. Sci. 2021, 12, 1479-1485
  1. Inhibitors of Thiol-Mediated Uptake
    Cheng, Y.; Pham, A.-T.; Kato, T.; Lim, B.; Moreau, D.; López-Andarias, J.; Zong, L.; Sakai, N.; Matile, S.
    Chem. Sci. 2021, 12, 626-631
  1. Oligomers of Cyclic Oligochalcogenides for Enhanced Cellular Uptake
    Martinent, R.; Du, D.; López-Andarias, J.; Sakai, N.; Matile, S.
    ChemBioChem 2021, 22, 253-259