UNIVERSITÉ DE GENÈVE

FACULTÉ DE MÉDECINE

Section de Médecine Dentaire
Département de Thérapeutique buccale et Orthodontie
Division de Physiopathologie buccale et Parodontie

Nouveau système résorbable pour la libération locale d'agents antimicrobiens dans les poches parodontales

Thèse
présentée à la Faculté de Médecine de l'Université de Genève
pour obtenir le grade de Docteur en Médecine Dentaire,

par

Pierre-Jean LOUP

(de Môtiers / Suisse)

sous la direction du
Pr Andrea Mombelli

Thèse n° Méd. dent. 622

Genève, 2002

      This study was performed in collaboration with the Department of Pharmaceutics and Biopharmaceutics, School of Pharmacy, University of Geneva, and the Division of Preventive Dentistry, School of Dental Medicine, University of Geneva.

      Sincere thanks are due to Doctor Khadija Schwach-Abdellaoui and Professor Robert Gurny, Department of Pharmaceutics and Biopharmaceutics, for the development, preparation and preliminary in vitro testing of the product.

      Doctor Nathalie Vivien-Castioni and Professor Pierre Baehni, Division of Preventive Dentistry, are gratefully acknowledged for their contribution to the clinical part of the study, including clinical assistance and logistic support.

      This study was supported in part by grant #32-46795 Swiss National Science Foundation and Advanced Polymer Systems, CA, USA.