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Our research focuses on molecular and supramolecular systems with interesting functions, supramolecular chemistry in action, at work, with emphasis on conceptual innovation, the integration of unorthodox interactions, and applications to significant challenges in science and society. Functions of current interest include catalysis (anion-π interactions, chalcogen, pnictogen bonds), fluorescent probes (mechanochemistry) and cellular uptake (dynamic covalent exchange cascades, antivirals). Our research is supported by a CH-ERC Advanced Grant, an SNSF Excellence Grant, and a National Centre of Competence in Research (NCCR). Click here for application information.

Latest Publications 

All publications 

Chen, H.; Frontera, A.; Gutiérrez López, M. Á.; Sakai, N.; Matile, S. “Pnictogen-Bonding Catalysts, Compared to Tetrel-Bonding Catalysts:  More Than Just Weak Lewis Acids” Helv. Chim. Acta 2022, in press

Shybeka, I.; Maynard, J. R. J.; Saidjalolov, S.; Moreau, D.; Sakai, N.; Matile, S. “Dynamic Covalent Michael Acceptors to Penetrate Cells:  Thiol-Mediated Uptake with Tetrel-Centered Exchange Cascades, Assisted by Halogen-Bonding Switches” Angew. Chem. Int. Ed. 2022, in press

Declas, N.; Maynard, J.; Menin, L.; Gasilova, N.; Götze, S.; Sprague, J.; Stallforth, P.; Matile, S.; Waser, J. “Tyrosine Bioconjugation with Hypervalent Iodine” Chem. Sci. 2022, 13, 12808-12817

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