Welcome to our web site

Our research focuses on molecular and supramolecular systems with interesting functions, supramolecular chemistry in action, at work, with emphasis on conceptual innovation, the integration of unorthodox interactions, and applications to challenges in nature. Functions of current interest include catalysis (anion-π interactions, chalcogen bonds), fluorescent probes (mechanochemistry) and cellular uptake (extreme sulfur and selenium chemistry). Click here for application information.

Latest Publications


Matile, S. “In My Element: Sulfur”, Chem. Eur. J. 2019, in press.

Pulcu, G. S.; Galenkamp, N. S.; Qing, Y.; Gasparini, G.; Mikhailova, E.; Matile, S.; Bayley, H. “Single-Molecule Kinetics of Growth and Degradation of Cell-Penetrating Poly(disulfide)s”, J. Am. Chem. Soc. 2019, in press.

Bartolami, E.; Basagiannis, D.; Zong, L.; Martinent, R.; Okamoto, Y.; Laurent, Q.; Ward, T. R.; Gonzalez-Gaitan, M.; Sakai, N.; Matile, S. “Diselenolane-Mediated Cellular Uptake:  Efficient Cytosolic Delivery of Probes, Peptides, Proteins, Artificial Metalloenzymes and Protein-Coated Quantum Dots”, Chem. Eur. J. 2019, 25, 4047-4051.

What's New

Feb 19: Outside its easy, inside its tough: Press release on chemistry tools to image physical forces inside living cells, otherwise undetectable.

Dec: Our flipper probes, made to image membrane tension in live cells, are now commercially available.

Oct: Former group member Javier Montenegro won Real Sociedad Española de Química prize. Congratulations!

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