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Our research focuses on molecular and supramolecular systems with interesting functions, supramolecular chemistry in action, at work, with emphasis on conceptual innovation, the integration of unorthodox interactions, and applications to challenges in nature. Functions of current interest include catalysis (anion-π interactions, chalcogen bonds), fluorescent probes (mechanochemistry) and cellular uptake (extreme sulfur and selenium chemistry). Click here for application information.

Latest Publications


Martinent, R.; López-Andarias, J.; Moreau, D.; Cheng, Y.; Sakai, N.; Matile, S. “Automated High-Content Imaging for Cellular Uptake, from the Schmuck Cation to the Latest Cyclic Oligochalcogenides”, Beilstein J. Org. Chem. 2020, in press.

Straková, K.; López-Andarias, J.; Jiménez-Rojo, N.; Chambers, J. E.; Marciniak, S. J.; Riezman, H.; Sakai, N.; Matile, S. “HaloFlippers:  A General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells”, ACS Cent. Sci. 2020, in press.

Kato, T.; Strakova, K.; García-Calvo, J.; Sakai, N.; Matile, S. “Mechanosensitive Fluorescent Probes, Changing Color Like Lobsters During Cooking:  Cascade Switching Variations”, Bull. Chem. Soc. Jpn. 2020, in press.

What's New more on twitter

March 20: Press release on access to forbidden rings.

Aug: Karolina Strakova and Anh-Tuan Pham won poster awards at ISHC27 in Kyoto and ICNI2019 in Lisbon, respectively. Congratulations!

Feb 19: Outside its easy, inside its tough: Press release on chemistry tools to image physical forces inside living cells, otherwise undetectable.

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