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Our research focuses on molecular and supramolecular systems with interesting functions, supramolecular chemistry in action, at work, with emphasis on conceptual innovation, the integration of unorthodox interactions, and applications to challenges in nature. Functions of current interest include catalysis (anion-π interactions, chalcogen bonds), fluorescent probes (mechanochemistry) and cellular uptake (extreme sulfur and selenium chemistry). Click here for application information.

Latest Publications

Oberhauser, L.; Granziera, S.; Colom, A.; Goujon, A.; Lavallard, V.; Matile, S.; Roux, A.; Brun, T.; Maechler, P. “Palmitate and Oleate Modify Membrane Fluidity and Kinase Activities of INS-1E ß-Cells Alongside Altered Metabolism-Secretion Coupling”, Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 2020, 1867, 118619.

Humeniuk, H. V.; Licari, G.; Vauthey, E.; Sakai, N.; Matile, S. “Mechanosensitive Membrane Probes:  Push-Pull Papillons”, Supramol. Chem. 2020, in press.

Zhang, X.; Sakai, N.; Matile, S. “Methyl Scanning for Mechanochemical Chalcogen-Bonding Cascade Switches”, ChemistryOpen 2020, 9, 18-22.

What's New more on twitter

Aug: Karolina Strakova and Anh-Tuan Pham won poster awards at ISHC27 in Kyoto and ICNI2019 in Lisbon, respectively. Congratulations!

Feb 19: Outside its easy, inside its tough: Press release on chemistry tools to image physical forces inside living cells, otherwise undetectable.

Dec: Our flipper probes, made to image membrane tension in live cells, are now commercially available.

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