- Vargas Jentzsch, A.; Emery, D.; Mareda, J.; Metrangolo, P.; Resnati, G.; Matile, S. “Ditopic Ion Transport Systems: Anion-π Interactions and Halogen Bonds at Work” Angew. Chem. Int. Ed. 2011, 50, 11675-11678
Single-atom exchange series are introduced to extract the individual contributions of halogen bonds and anion-π interactions to the transport of anions across lipid bilayer membranes (see picture). Known cation binding sites are used for counterion activation of the neutral calixarene transporters. The experimental evidence for anion transport with halogen bonds is unprecedented.