Dubochet Center for Imaging Geneva (DCI Geneva)
DCI Geneva offer access to electron microscopy (EM) techniques, equipment and expertise.
The facility offers users access to cutting-edge cryo-electron microscopy (cryoEM), covering both single-particle analysis (SPA) and cryo-electron tomography (cryoET) techniques, in addition to a range of room temperature EM methods.
We also offer structure determination of protein and small molecule microcrystals by electron diffraction (microED). The facility provides full training on all instruments and aims for users to be able to operate equipment independently.
Facility staff are available to consult at all stages of experimental design and sample optimisation, through to data collection strategies and data processing. Access to techniques may also be available as a full service from facility staff.
Equipment
Microscopes & sample preparation equipment
- TFS Talos Arctica 200kV cryo-TEM
Equiped with Falcon4i detector & SelectrisX energy filter - TFS Talos L120C 120kV TEM
- FEI Tecnai G2 Sphera 200kV TEM
Equiped with ASI CheeTah hybrid pixel detector for microED - Leica EM-GP2 cryo-plunger
- TFS Vitrobot Mk.IV cryo-plunger
- Leica ICE High Pressure Freezer
- Leica AFS/FSP Freeze Substitution
- Leica UC7 Ultramicrotome
- Leica Thunder Cryo-CLEM
- GPU workstation for cryoEM data pre-processing
Services
- Consulting on techniques, instrument choice and experimental design for electron microscopy experiments.
- Training and assistance in operation of microscopes and sample preparation equipment.
- Support for data processing
- Data collection as a service
- Basic EM courses, including image processing
Keywords
Address
Sciences II/III
30 quai Ernest-Ansermet
1211 Genève 4