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Our research focuses on molecular and supramolecular systems with interesting functions, supramolecular chemistry in action, at work, with emphasis on conceptual innovation, the integration of unorthodox interactions, and applications to significant challenges in science and society. Functions of current interest include catalysis (electric fields, electromicrofluidics; anion-π interactions; chalcogen, pnictogen bonds), cellular uptake (dynamic covalent exchange cascades; delivery; dynamers) and fluorescent probes to image forces in biology (flippers, commercialized). Click here for application information.

Latest Publications 

All publications 

Cognet, M.; Renno, G.; Rose, N.; Zhang, Y.; Josso, P.; Moreno, J.; Ren, X.; Bouffard, J.; Saidjalolov, S.; Sakai, N.; Matile, S. “Cell-Penetrating Poly(disulfide)s” Helv. Chim. Acta 2025, in press

Cognet, M.; Renno, G.; Coelho, F.; Sakai, N.; Matile, S. “Grafting Cell-Penetrating Poly(disulfide)s to Substrates of Interest:  Dynamic Covalent Bioconjugation for Traceless Delivery” Angew. Chem. Int. Ed. 2025, in press

Bouffard, J.; Bayard, F.; Sakai, N.; Matile, S. “Thiol-Mediated Uptake of Phosphorothioate Liposomes, Visualized with Fluorescent Flippers” Chem. Sci. 2025, 16, 18599-18606

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