181. S. Chappellet, P. Müller,
     “Ru-Catalyzed Enantioselective Dipolar Cycloadditions of Ethyl Diazopyruvate”
     Synlett 2004, 2573-2575.

The decomposition of ethyl diazopyruvate (1) with [RuCl₂(pybox)] catalysts in the presence of enol ethers affords ­dihydrofurans derived from formal 1,3-cycloaddition. Enantio­selectivities of up to 74% have been achieved.

DOI : 10.1055/s-2004-834796