169. Optically pure, crystalline 'acetate'-aldols from N-acetylbornane-10,2-sultam
     Oppolzer, W.; Starkemann, C.
     Tetrahedron Lett. 1992, 33, 2439-2442

O-Silylation of N-acetylsultam 2 gives O-silyl-N,O-ketene acetal 3 which undergoes TiCl₄promoted addition to aromatic and aliphatic aldehydes to afford, after flash chromatography, diastereomerically pure, crystalline aldols 5 which are readily converted to enantiomerically pure β-hydroxy carboxylic acids or esters.

DOI : 10.1016/S0040-4039(00)92209-3 

archive ouverte unige:152219