211. Towards the Asymmetric Synthesis of Ascochlorin
     Dogan, Ö.; Oppolzer, W.
     Turk. J. Chem. 2001, 25, 273-281

A synthetic approach is described to the asymmetric synthesis of ascochlorin (1), an antiviral antibiotic, based on the construction of a sesquiterpene unit via asymmetric Diels-Alder reaction of tigloyl sultam 4 & butadiene, and the introduction of the aromatic side chain (C9-C12 unit) by employing cuprate chemistry.

Lien : http://journals.tubitak.gov.tr/chem/abstract.htm?id=4676