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Publication 191  

  1. Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores
    Christoph Ruediger Bauer, Romain Duwald, Geraldine Labrador, Simon Pascal, Pau Moneva Lorente, Johann Bosson, Jérôme Lacour, Jean-David Rochaix
    Org. Biomol. Chem. 2018, 16, 919-923

Thirteen cationic helicenes and triangulene were tested for the specific labeling of mitochondria from algal cells. Octyl ester derivative 5 readily penetrates algal cells and gives rise to clear fluorescence patterns when it is used at concentrations in the mM range. Under these conditions, cell structures are well preserved and cell survival is not compromised. Cationic helicene compounds such as 5 provide new useful tools for examining the mitochondrial network and its dynamics including fission and fusion events

DOI: 10.1039/C7OB02906C 

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