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- Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis
C. Serba, N. Winssinger
Eur. J. Org. Chem. 2013, 4195-4214
This microreview discusses recent efforts in chemical synthesis to design divergent pathways either to access diverse natural products from a common intermediate or to produce diverse libraries of compounds reminiscent of natural products. These efforts are generally based on the development and use of powerful complexity-generating reactions and cascade reactions. A panel of eighteen examples is used to illustrate different strategies.
DOI : 10.1002/ejoc.201300201
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