85. An Enantioselective CpRu Catalyzed Carroll Rearrangement
    Samuel Constant, Simone Tortoioli, Jessica Müller, Jérôme Lacour
    Angew. Chem. Int. Ed. 2007, 46, 2082-2085
    [ This study was highlighted in Synfacts. ]

Simple ligands, catalyst, and conditions: The combination of readily prepared unsymmetrical pyridine–imine ligands and [CpRu(CH₃CN)₃][PF₆] (Cp=C₅H₅) affords regio- and enantioselective Carroll rearrangements (see scheme; b/l= branched-to-linear ratio). This reaction represents the first example of Ru-catalyzed enantioselective CC bond-forming allylic substitution.

DOI: 10.1002/anie.200604573 

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