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Publication 6  

  1. Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library
    K. C. Nicolaou, J. Pastor, N. Winssinger, F. Murphy
    J. Am. Chem. Soc. 1998, 120, 5132-5133

The authors describe the construction of a muscone library using the powerful intramol. ketophosphonate-aldehyde condensation reaction. This adds another chem. to the solid-phase reaction library and demonstrates its power in the synthesis of natural products.

DOI: 10.1021/ja980675q 

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