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Publication 69  

  1. Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action
    J. Garcia, S. Barluenga, K. Beebe, L. Neckers, N. Winssinger
    Chem. Eur. J. 2010, 16, 9767-9771

The concise nature and modularity of the synthesis described for deguelin and tephrosin (retrosynthetic analysis depicted) should facilitate access to labeled analogues to dissect the mechanism of action of this important pharmacophore.

DOI: 10.1002/chem.201001080 

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