81. Cu-Catalyzed Enantioselective Protoboration of 2,3-Disubstituted 1,3-Dienes
    Sensheng Liu, Yangbin Liu, Arthur Flaget, Cheng Zhang, Clément Mazet*
    Org. Lett. 2023, 25, 6897-6901

A Cu-catalyzed regio- and enantioselective protoboration of 2,3-disubstituted 1,3-dienes is described. The protocol operates under mild conditions and is applicable to symmetrically and unsymmetrically substituted dienes, providing access to homoallylic boronates in consistently high yield, regioselectivity, and enantiomeric ratio. Preliminary investigations point to a complex mechanism.

archive ouverte unige:173868

DOI de la version éditeur : 10.1021/acs.orglett.3c02627 (open access)

DOI du Dataset : 10.26037/yareta:nxnz5ur3wjenlcqfwru4jdyycu