Clinical Pharmacology and Therapeutics (November 2016) SITE

  • Clin Pharmacol Ther. 2016;100:398-403. Drug transporters: advances and opportunities. Govindarajan R, Sparreboom A. Introduction to the issue. PubMed
  • Clin Pharmacol Ther. 2016;100:413-418. Transport vs. metabolism: what determines the pharmacokinetics and pharmacodynamics of drugs? Insights from the extended clearance model. Patilea-Vrana G, Unadkat JD. PubMed
  • Clin Pharmacol Ther. 2016;100:419-422. Highlights from the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on drug transporters in absorption, distribution, metabolism, and excretion: from the bench to the bedside - clinical pharmacology considerations. Ronaldson PT, Bauer B, El-Kattan AF, Shen H, Salphati L, Louie SW. PubMed
  • Clin Pharmacol Ther. 2016;100:524-536. Metabolomic and genome-wide association studies reveal potential endogenous biomarkers for OATP1B1. Yee SW, Giacomini MM, Hsueh CH, Weitz D, Liang X, Goswami S, Kinchen JM, Coelho A, Zur AA, Mertsch K, Brian W, Kroetz DL, Giacomini KM. PubMed
  • Clin Pharmacol Ther. 2016;100:423-426. Genomewide association studies in pharmacogenomics: meeting report of the NIH pharmacogenomics research network-RIKEN (PGRN-RIKEN) collaboration. Yee SW, Momozawa Y, Kamatani Y, Tyndale RF, Weinshilboum RM, Ratain MJ, Giacomini KM, Kubo M. Bissa B, Beedle AM. PubMed
  • Clin Pharmacol Ther. 2016;100:437-440. Transporters affecting biochemical test results: creatinine-drug interactions. Chu X, Bleasby K, Chan GH, Nunes I, Evers R. PubMed
  • Clin Pharmacol Ther. 2016;100:441-453. Transporters as drug targets in neurological diseases. Qosa H, Mohamed LA, Alqahtani S, Abuasal BS, Hill RA, Kaddoumi A. PubMed
  • Clin Pharmacol Ther. 2016;100:464-478. Liver and kidney on chips: microphysiological models to understand transporter function. Chang SY, Weber EJ, Ness KV, Eaton DL, Kelly EJ. PubMed
  • Clin Pharmacol Ther. 2016;100:479-488. Imaging transporters: transforming diagnostic and therapeutic development. Mann A, Han H, Eyal S. PubMed
  • Clin Pharmacol Ther. 2016;100:513-523. Quantitative analyses of hepatic OATP-mediated interactions between statins and inhibitors using PBPK modeling with a parameter optimization method. Yoshikado T, Yoshida K, Kotani N, Nakada T, Asaumi R, Toshimoto K, Maeda K, Kusuhara H, Sugiyama Y. PubMed