Susanne KEIDING GROUP   SITE

Susan Keiding (MD, PhD) is Associate Professor at the Aarhus University (Denmark), Honorary Professor at the Copenhagen University and director of the Liver PET Research group at the University Hospital of Aarhus. She is also consultant physician at the Department of Hepatology and Gastroenterology and at the PET Centre (University Hospital of Aarhus, Denmark).

She obtained her specialisation in Medical Gastroenterology, Hepatology, and Internal Medicine and her PhD thesis on "Galactose elimination in intact pig liver". She is responsible for postdoctoral scientific training in Physiology, Biochemistry, Biophysics, Mathematics, Statistics, Experimental and Clinical Hepatology at the University of Copenhagen (Denmark). Along her carrier, she visited the Department of Mathematics at Queensland University (Brisbane, Australia), the department of Hepatology at Mayo Clinic (Minnesota, USA), Liver Transplantation Unit at Gröningen University Hospital (The Netherlands) and Liver Unit at University of California (San Francisco, USA). Visiting periods lasted between 1 to 12 months.

She published 150 original and review articles in peer-refereed scientific journals and 53 book chapters, editorials, letter-to-the Editor and articles in Danish. She is Editor of the e-book entitled  "Functional Molecular Imaging in Hepatology" (Bentham Science Publishers) published in 2012. She is a regular reviewer for Hepatology, Gastroenterology, Journal of Hepatology, Journal of Nuclear Molecular Imaging, Journal of Cerebral Blood Flow and Metabolism, European Journal of Nuclear Medicine and Molecular Imaging, Journal of Theoretical Biology, Scandinavian Journal of Gastroenterology. In total, she supervised more than 30 PhD students and young researchers.

  • J Hepatol. J Hepatol. 2021;74:58-65. Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis. Kjærgaard K, Frisch K, Sørensen M, Munk OL, Hofmann AF, Horsager J, Schacht AC, Erickson M, Shapiro D, Keiding S.  PubMed
  • Liver Int. 2020;40:447-455. [18 F]-Fluoro-2-deoxy-D-galactose positron emission tomography/computed tomography as complementary imaging tool in patients with hepatocellular carcinoma. Bak-Fredslund KP, Keiding S, Villadsen GE, Kramer S, Schlander S, Sørensen M. PubMed
  • Dig Dis Sci. 2018;63:3153-3157. β-blockers improve presinusoidal portal hypertension. Sørensen M, Larsen LP, Villadsen GE, Aagaard NK, Grønbæk H, Keiding S, Vilstrup H. PubMed
  • Eur J Radiol. 2019;113:101-109. Prognostic modeling for patients with colorectal liver metastases incorporating FDG PET radiomic features. Rahmim A, Bak-Fredslund KP, Ashrafinia S, Lu L, Schmidtlein CR, Subramaniam RM, Morsing A, Keiding S, Horsager J, Munk OL. PubMed
  • Nucl Med Biol. 2018;61:56-62. N-(4-[18F]fluorobenzyl)cholylglycine, a novel tracer for PET of enterohepatic circulation of bile acids: Radiosynthesis and proof-of-concept studies in rats. Frisch K, Stimson DHR, Venkatachalam T, Pierens GK, Keiding S, Reutens D, Bhalla R. PubMed
  • Am J Nucl Med Mol Imaging. 2018;8:73-85. Quantitative PET of liver functions. Keiding S, Sørensen M, Frisch K, Gormsen LC, Munk OL. PubMed
  • Biochim Biophys Acta. 2018;1864:1240-1244. Functional assessment of hepatobiliary secretion by 11C-cholylsarcosine positron emission tomography. Ørntoft N, Frisch K, Ott P1, Keiding S, Sørensen M. PubMed
  • Phys Med Biol. 2017;63:015032. A microvascular compartment model validated using 11C-methylglucose liver PET in pigs. Munk OL, Keiding S, Baker C, Bass L. PubMed
  • Am J Nucl Med Mol Imaging. 2017;7(4):167-173. Hepatic metabolism of 11C-methionine and secretion of 11C-protein measured by PET in pigs. Horsager J, Lausten SB, Bender D, Munk OL, Keiding S. PubMed
  • EJNMMI Res. 2017;7(1):71. Metabolic liver function in humans measured by 2-18F-fluoro-2-deoxy-D-galactose PET/CT-reproducibility and clinical potential. Bak-Fredslund KP, Lykke Eriksen P, Munk OL, Villadsen GE, Keiding S, Sørensen M. PubMed
  • J Hepatol. 2017; 67:321-327. Hepatobiliary transport kinetics of the conjugated bile acid tracer 11C-CSar quantified in healthy humans and patients by Positron Emission Tomography (PET). Ørntoft NW, Munk OL, Frisch K, Ott P, Keiding S, Sørensen M. PubMed
  • Nucl Med Biol. 2016;43:577-80. 2-[(18)F]fluoro-2-deoxy-D-galactose PET/CT of hepatocellular carcinoma is not improved by co-administration of galactose. Bak-Fredslund KP, Munk OL, Keiding S, Sørensen M. PubMed
  • J Nucl Med. 2016:961-6. Hepatobiliary secretion kinetics of conjugated bile acids measured in pigs by 11C-Cholylsarcosine PET. Sørensen M, Munk OL, Ørntoft NW, Frisch K, Andersen KJ, Mortensen FV, Alstrup AK, Ott P, Hofmann AF, Keiding S. PubMed
  • J Hepatol. 2013;58:1119-24. Regional metabolic liver function measured in patients with cirrhosis by 2-[¹⁸F]fluoro-2-deoxy-D-galactose PET/CT. Sørensen M, Mikkelsen KS, Frisch K, Villadsen GE, Keiding S. PubMed
  • Invest Radiol. 2012;47:588-95. Hepatic blood perfusion estimated by dynamic contrast-enhanced computed tomography in pigs: limitations of the slope method. Winterdahl M, Sørensen M, Keiding S, Mortensen FV, Alstrup AK, Hansen SB, Munk OL. PubMed
  • J Nucl Med. 2012;53:425-33. Bringing physiology into PET of the liver. Keiding S. PubMedJ Nucl Med. 2011;52:1119-24. Hepatic blood perfusion measured by 3-minute dynamic 18F-FDG PET in pigs. Winterdahl M, Munk OL, Sørensen M, Mortensen FV, Keiding S. PubMed

Informative image: metabolic clearance (Kmet) of 18F-FDGalactose

Healthy subject with Kmet = 0.27 mL blood/mL liver tissue/min and cirrhotic patient with Kmet =  0.16 mL blood/mL liver tissue/min. Publication

CLMET.jpg

PubMed

Aarhus, Denmark

KEIDING SUSANNE.jpg

Last update: August 2021