1. A Bis(oxazolinyl)pyrrole as a New Monoanionic Tridentate Supporting Ligand: Synthesis of a Highly Active Palladium Catalyst for Suzuki-Type C-C Coupling
   Clément Mazet, Lutz H. Gade*
   Organometallics 2001, 20, 4144-4146

Reaction of pyrrole-2,5-biscarbonitrile with 2-amino-2-methyl-1-propanol gave the bis{2-(4,4’-dimethyl-4,5-dihydrooxazolyl)}pyrrole (dmoxpH) (1), which was deprotonated and reacted with [PdCl₂(COD] to give [Pd₂(dmoxp)₂Cl₂] (2) and [Pd₃(dmoxp)₂Cl₄] (3). The former is an active catalyst in the Suzuki cross coupling of phenylboronic acid with activated and nonactivated aryl bromides at 70 °C and catalyst/substrate ratios of 10^-4 to 10^-5.

archive ouverte unige:6940

DOI de la version éditeur : 10.1021/om010586d